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mitomycin and Cancer of the Vulva

mitomycin has been researched along with Cancer of the Vulva in 25 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"Thirty-one patients with squamous cell carcinoma of the vulva were treated with two courses of combination chemotherapy mitomycin C, 15 mg/m2 intravenously (i."2.68Combined preoperative chemoradiotherapy followed by radical surgery in locally advanced vulvar carcinoma. A pilot study. ( di Re, F; Fontanelli, R; Kenda, R; Lupi, G; Paladini, D; Raspagliesi, F; Zucali, R, 1996)
"A clinical trial was performed to investigate the efficacy of hyperthermia in combination with chemotherapy for gynecological malignancies."2.66Therapeutic effect of hyperthermia combined with chemotherapy on vulvar and vaginal carcinoma. ( Fujiwara, K; Kohno, I; Sekiba, K, 1987)
"The subject was a patient who had squamous cell carcinoma in the pudendum and the inguinal region (12."1.30[A case of FIGO stage IV A vulvar cancer successfully treated by neoadjuvant chemotherapy with continuous intra-arterial infusion (cisplatin, 5-fluorouracil)]. ( Narimatsu, A; Okada, O, 1997)
"No effective chemotherapy for advanced extramammary Paget's disease has yet been established."1.28Metastatic vulvar Paget's disease responding to combination chemotherapy: case report. ( Kawabata, I; Mabuchi, M; Niwa, K; Shimokawa, K; Tamaya, T; Yokoyama, Y, 1990)
"Twenty-one patients with squamous carcinoma of the genital tract were treated with bleomycin, Oncovin, mitomycin-C, and cisplatin (BOMP)."1.27Bleomycin, vincristine, mitomycin-C, and cisplatin in the management of gynecological squamous cell carcinomas. ( Belinson, JL; McClure, M; Richards, AL; Stewart, JA, 1985)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19908 (32.00)18.7374
1990's10 (40.00)18.2507
2000's4 (16.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Linz, VC1
Schwanbeck, C1
Krajnak, S1
Anic, K1
Jäkel, J1
Schwab, R1
Schmidt, M1
Schmidberger, H1
Hasenburg, A1
Battista, MJ1
Oashi, K1
Tsutsumida, A1
Namikawa, K1
Tanaka, R1
Omata, W1
Yamamoto, Y1
Yamazaki, N1
Rogers, LJ1
Howard, B1
Van Wijk, L1
Wei, W1
Dehaeck, K1
Soeters, R1
Denny, LA1
Tans, L1
Ansink, AC1
van Rooij, PH1
Kleijnen, C1
Mens, JW1
Mulayim, N1
Foster Silver, D1
Schwartz, PE1
Higgins, S1
Satoh, S1
Suzuki, A1
Okamura, H1
Nishimura, T1
Zhao, LR1
Zhao, WX1
Shao, MH1
Wahlen, SA1
Slater, JD1
Wagner, RJ1
Wang, WA1
Keeney, ED1
Hocko, JM1
King, A1
Slater, JM1
Tamada, T1
Hayase, R1
Seki, A1
Yamamoto, J1
Kodama, J1
Yoshinouchi, M1
Kobashi, Y1
Okuda, H1
Kudo, T1
Koh, WJ1
Wallace, HJ1
Greer, BE1
Cain, J1
Stelzer, KJ1
Russell, KJ1
Tamimi, HK1
Figge, DC1
Russell, AH1
Griffin, TW1
Lupi, G1
Raspagliesi, F1
Zucali, R1
Fontanelli, R1
Paladini, D1
Kenda, R1
di Re, F1
Landoni, F1
Maneo, A1
Zanetta, G1
Colombo, A1
Nava, S1
Placa, F1
Tancini, G1
Mangioni, C1
Narimatsu, A1
Okada, O1
Han, SC1
Kim, DH1
Higgins, SA1
Carcangiu, ML1
Kacinski, BM1
Akl, A1
Akl, M1
Boike, G1
Hebert, J1
Graham, J1
Shimizu, Y2
Hasumi, K2
Masubuchi, K2
Whitaker, SJ1
Kirkbride, P1
Arnott, SJ1
Hudson, CN1
Shepherd, JH1
Yokoyama, Y1
Mabuchi, M1
Kawabata, I1
Niwa, K1
Shimokawa, K1
Tamaya, T1
Yasui, Y1
Suzumori, K1
Asai, H1
Yagami, Y1
Fujiwara, K1
Kohno, I1
Sekiba, K1
Yakabe, A1
Yamashita, S1
Kinashi, N1
Ito, T1
Yagi, H1
Nakayama, K1
Chen, JT1
Hirai, Y1
Hamada, T1
Fujimoto, I1
Yamauchi, K1
Thomas, G1
Dembo, A1
DePetrillo, A1
Pringle, J1
Ackerman, I1
Bryson, P1
Balogh, J1
Osborne, R1
Rosen, B1
Fyles, A1
Belinson, JL1
Stewart, JA1
Richards, AL1
McClure, M1
Evans, LS1
Kersh, CR1
Constable, WC1
Taylor, PT1

Reviews

2 reviews available for mitomycin and Cancer of the Vulva

ArticleYear
Combined radiotherapy and chemotherapy in the management of local-regionally advanced vulvar cancer.
    International journal of radiation oncology, biology, physics, 1993, Aug-01, Volume: 26, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1993
Preliminary results of chemoradiation as a primary treatment for vulvar carcinoma.
    International journal of radiation oncology, biology, physics, 2000, Sep-01, Volume: 48, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; C

2000

Trials

5 trials available for mitomycin and Cancer of the Vulva

ArticleYear
The role of chemo-radiotherapy in the management of locally advanced carcinoma of the vulva: single institutional experience and review of literature.
    American journal of clinical oncology, 2011, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2011
[Combination chemotherapy of peplomycin, vincristine, mitomycin C, and cisplatin in gynecologic carcinomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Genital Neoplasms, F

1994
Combined radiotherapy and chemotherapy in the management of local-regionally advanced vulvar cancer.
    International journal of radiation oncology, biology, physics, 1993, Aug-01, Volume: 26, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1993
Combined preoperative chemoradiotherapy followed by radical surgery in locally advanced vulvar carcinoma. A pilot study.
    Cancer, 1996, Apr-15, Volume: 77, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

1996
Therapeutic effect of hyperthermia combined with chemotherapy on vulvar and vaginal carcinoma.
    Acta medica Okayama, 1987, Volume: 41, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; F

1987

Other Studies

19 other studies available for mitomycin and Cancer of the Vulva

ArticleYear
Comparison of cisplatin and mitomycin C/5-FU as radiosensitisers in the treatment of locally advanced vulvar cancer: results of a retrospective, observational, single-institutional cohort study.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cohort Studies; Female; Fluorouracil; Hum

2023
Combination chemotherapy for metastatic extramammary Paget disease.
    The British journal of dermatology, 2014, Volume: 170, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Neopla

2014
Chemoradiation in advanced vulval carcinoma.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2009, Volume: 19, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

2009
Chemoradiation with 5-fluorouracil and mitomycin C in the treatment of vulvar squamous cell carcinoma.
    Gynecologic oncology, 2004, Volume: 93, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuva

2004
[Case of malignant melanoma of the external genitalia responding satisfactorily to a combination of local injection of OK-432 and chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:1

    Topics: Adjuvants, Immunologic; Antineoplastic Agents; Biological Products; Cyclophosphamide; Drug Administr

1982
[Treatment of advanced and recurrent gynecologic cancer with chemotherapy by cannula perfusion into both internal iliac arteries].
    Zhonghua fu chan ke za zhi, 1994, Volume: 29, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci

1994
Concurrent radiation therapy and chemotherapy in the treatment of primary squamous cell carcinoma of the vulva.
    Cancer, 1995, May-01, Volume: 75, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carci

1995
Concurrent preoperative chemotherapy with 5-fluorouracil and mitomycin C and radiotherapy (FUMIR) followed by limited surgery in locally advanced and recurrent vulvar carcinoma.
    Gynecologic oncology, 1996, Volume: 61, Issue:3

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

1996
[A case of FIGO stage IV A vulvar cancer successfully treated by neoadjuvant chemotherapy with continuous intra-arterial infusion (cisplatin, 5-fluorouracil)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemother

1997
Chemoradiation as primary or adjuvant treatment for locally advanced carcinoma of the vulva.
    International journal of radiation oncology, biology, physics, 2000, Jul-15, Volume: 47, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

2000
Effective chemotherapy consisting of bleomycin, vincristine, mitomycin C, and cisplatin (BOMP) for a patient with inoperable vulvar cancer.
    Gynecologic oncology, 1990, Volume: 36, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Comb

1990
A pilot study of chemo-radiotherapy in advanced carcinoma of the vulva.
    British journal of obstetrics and gynaecology, 1990, Volume: 97, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouraci

1990
Metastatic vulvar Paget's disease responding to combination chemotherapy: case report.
    Japanese journal of clinical oncology, 1990, Volume: 20, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Cisplatin; Female; H

1990
[Combination chemotherapy with peplomycin, cis-platinum and mitomycin C in gynecologic cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:11

    Topics: Adenocarcinoma; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols;

1985
[Local injection of OK-432 and mitomycin C into vulvar cancer responding poorly to bleomycin and linac irradiation].
    Nihon Gan Chiryo Gakkai shi, 1987, May-20, Volume: 22, Issue:4

    Topics: Aged; Biological Products; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; H

1987
[Chemotherapy of a patient with FIGO stage IV vulvar cancer with bleomycin, vincristine, mitomycin C, and cisplatin].
    Nihon Sanka Fujinka Gakkai zasshi, 1989, Volume: 41, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fema

1989
Concurrent radiation and chemotherapy in vulvar carcinoma.
    Gynecologic oncology, 1989, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone

1989
Bleomycin, vincristine, mitomycin-C, and cisplatin in the management of gynecological squamous cell carcinomas.
    Gynecologic oncology, 1985, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, S

1985
Concomitant 5-fluorouracil, mitomycin-C, and radiotherapy for advanced gynecologic malignancies.
    International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

1988