Page last updated: 2024-11-06

mitomycin and Cancer of the Urinary Tract

mitomycin has been researched along with Cancer of the Urinary Tract in 20 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
" Patient demographics, the timing of MMC instillation, adverse events (surgical and potentially MMC-related) and length of stay (LOS) were assessed according to the Clavien-Dindo classification."1.56Safety and feasibility of early single-dose mitomycin C bladder instillation after robot-assisted radical nephroureterectomy. ( Barod, R; Bex, A; Cullen, D; Gulamhusein, A; Mumtaz, F; Patki, P; Silva, P; Tran, M, 2020)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's3 (15.00)18.2507
2000's4 (20.00)29.6817
2010's5 (25.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Dreicer, R1
Gulamhusein, A1
Silva, P1
Cullen, D1
Tran, M1
Mumtaz, F1
Patki, P1
Barod, R1
Bex, A1
Porta, C1
Giannatempo, P1
Rizzo, M1
Lucarelli, G1
Ditonno, P1
Battaglia, M1
Somani, BK1
Chen, SK1
Chung, CA1
Cheng, YC1
Huang, CJ1
Ruaan, RC1
Chen, WY1
Li, C1
Tsao, CW1
Hu, WW1
Chien, CC1
Seisen, T1
Colin, P1
Rouprêt, M1
Bhattacharyya, M1
Powles, T1
Mutsvangwa, K1
Wilson, P1
Oliver, T1
Shamash, J1
Cutress, ML1
Stewart, GD1
Zakikhani, P1
Phipps, S1
Thomas, BG1
Tolley, DA1
Palou, J1
Piovesan, LF1
Huguet, J1
Salvador, J1
Vicente, J1
Villavicencio, H1
Di Stasi, SM1
Giannantoni, A1
Stephen, RL1
Storti, L1
Attisani, F1
Sansalone, S1
Virgili, G1
Fujihiro, S1
Takeuchi, T1
Fujimoto, Y1
Okano, M1
Horie, M1
Kanematsu, M1
Kuriyama, M1
Ban, Y1
Nishiura, T1
Tannock, IF1
Gaboardi, F1
Bozzola, A1
Dotti, E1
Galli, L1
Hayes, MC1
Birch, BR1
Cooper, AJ1
Primrose, JN1
Mitsumori, K1
Sato, K1
Kato, T1
Sahashi, M2
Ono, Y2
Matsuura, O1
Ohshima, S2
Fukushima, M1
Gelabert Mas, A1
Arango, O1
Rosales, A1
Coronado, J1
Moreno, A1
Fujita, T1
Aso, Y1
Aota, Y1
Murase, T1
Takashi, M1
Ito, H1
Shimoji, T1
Miyake, K1
Mitsuya, H1
Tari, K1
Satake, I1
Kojima, S1
Negishi, T1
Yoshida, K1
Nakame, Y1
Kanaoya, F1
Horiuchi, S1
Saito, T1
Owada, F1

Reviews

4 reviews available for mitomycin and Cancer of the Urinary Tract

ArticleYear
An evaluation of UGN-101, a sustained-release hydrogel polymer-based formulation containing mitomycin-C, for the treatment of upper urothelial carcinomas.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:18

    Topics: Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Clinical Trials as Topic; Delayed-Action

2020
Risk-adapted strategy for the kidney-sparing management of upper tract tumours.
    Nature reviews. Urology, 2015, Volume: 12, Issue:3

    Topics: Administration, Intravesical; Algorithms; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell;

2015
Ureteroscopic and percutaneous management of upper tract urothelial carcinoma (UTUC): systematic review.
    BJU international, 2012, Volume: 110, Issue:5

    Topics: Antibiotics, Antineoplastic; BCG Vaccine; Biopsy; Carcinoma, Transitional Cell; Chemotherapy, Adjuva

2012
[Intra-arterial chemotherapy in urological cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capsules; Carcinoma, Re

2002

Trials

3 trials available for mitomycin and Cancer of the Urinary Tract

ArticleYear
A phase II study of mitomycin, fluorouracil, folinic acid, and irinotecan (MFI) for the treatment of transitional cell carcinoma of the bladder.
    Urologic oncology, 2013, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoma, Transitional

2013
Combination chemotherapy for advanced urothelial-tract carcinoma.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30 Suppl

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin

1992
Three-drug combination chemotherapy for advanced urothelial tract carcinoma.
    Cancer chemotherapy and pharmacology, 1987, Volume: 20 Suppl

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Transitional Cell

1987

Other Studies

13 other studies available for mitomycin and Cancer of the Urinary Tract

ArticleYear
New mitomycin formulation for low-grade upper tract urothelial cancer.
    The Lancet. Oncology, 2020, Volume: 21, Issue:6

    Topics: Carcinoma, Transitional Cell; Humans; Mitomycin; Urologic Neoplasms; Urothelium

2020
Safety and feasibility of early single-dose mitomycin C bladder instillation after robot-assisted radical nephroureterectomy.
    BJU international, 2020, Volume: 126, Issue:6

    Topics: Administration, Intravesical; Aged; Antibiotics, Antineoplastic; Female; Humans; Male; Middle Aged;

2020
Editorial Comment on: Induction and Maintenance Adjuvant Mitomycin C Topical Therapy for Upper Tract Urothelial Carcinoma: Tolerability and Intermediate Term Outcomes by Metcalfe et al.
    Journal of endourology, 2017, Volume: 31, Issue:9

    Topics: Adjuvants, Immunologic; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Humans; Kidney Neoplas

2017
Hydrostatic pressure enhances mitomycin C induced apoptosis in urothelial carcinoma cells.
    Urologic oncology, 2014, Volume: 32, Issue:1

    Topics: Antibiotics, Antineoplastic; Apoptosis; Bioreactors; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Pr

2014
Percutaneous nephroscopic management of upper urinary tract transitional cell carcinoma: recurrence and long-term followup.
    The Journal of urology, 2004, Volume: 172, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Endo

2004
Percutaneous sequential bacillus Calmette-Guèrin and mitomycin C for panurothelial carcinomatosis.
    The Canadian journal of urology, 2005, Volume: 12, Issue:6

    Topics: Adjuvants, Immunologic; Antibiotics, Antineoplastic; BCG Vaccine; Carcinoma; Drug Therapy, Combinati

2005
[Chemotherapy of urothelial cancer with vincristine, mitomycin C, bleomycin, tegafur and OK-432].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Female;

1984
Methotrexate and mitomycin for patients with metastatic transitional cell carcinoma of the urinary tract.
    Cancer treatment reports, 1983, Volume: 67, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Drug Evaluation; Drug Therapy, Combination; Hum

1983
Conservative treatment of upper urinary tract tumors with Nd:YAG laser.
    Journal of endourology, 1994, Volume: 8, Issue:1

    Topics: Adult; Combined Modality Therapy; Endoscopy; Hematuria; Humans; Laser Therapy; Male; Mitomycin; Neop

1994
Cellular resistance to mitomycin C is associated with overexpression of MDR-1 in a urothelial cancer cell line (MGH-U1).
    BJU international, 2001, Volume: 87, Issue:3

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistanc

2001
Eosinophilic cystitis and allergy to mitomycin-C.
    Acta urologica Belgica, 1990, Volume: 58, Issue:3

    Topics: Aged; Antineoplastic Agents; Carcinoma, Transitional Cell; Cystitis; Eosinophilia; Female; Humans; M

1990
[A study of postoperative adjuvant chemotherapy of advanced urinary epithelial cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Transitional Cell; Cispl

1988
[Prophylactic intravesical chemotherapy in bladder tumors after surgery of upper tract urothelial carcinoma].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:6

    Topics: Administration, Intravesical; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilq

1987