mitomycin has been researched along with Cancer of the Urethra in 12 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From January 1991 to December 2006, 18 patients with invasive carcinoma of the male urethra referred to our institution were treated with a chemoradiation therapy protocol, consisting of 2 cycles of 5-fluorouracil (1,000 mg/m(2)) on days 1 to 4 and days 29 to 32, and mitomycin-C (10 mg/m(2)) on days 1 and 29 with concurrent external beam radiation therapy (45 to 55 Gy in 25 fractions during 5 weeks) to the genitalia, perineum, and inguinal and external iliac lymph nodes." | 3.74 | Coordinated chemoradiation therapy with genital preservation for the treatment of primary invasive carcinoma of the male urethra. ( Billmeyer, B; Cohen, MS; Girshovich, L; Hanley, RS; Oberfield, RA; Shuster, T; Triaca, V; Zinman, L, 2008) |
| "Patients with locally advanced squamous cell carcinoma of the bulbomembranous urethra fare poorly whether they undergo surgery or primary radiotherapy." | 1.29 | Combined chemoradiotherapy for locally advanced squamous cell carcinoma of the bulbomembranous urethra: a case report. ( Huang, DT; Lutz, ST, 1995) |
| "Mitomycin C has proved to be useful as prophylaxis against superficial bladder tumor recurrences." | 1.27 | Prostatic recurrences in the management of superficial bladder tumors. ( Bondhus, MJ; Chaikin, L; Lockhart, JL; Politano, VA, 1983) |
| "In case 1, a 73-year-old female with squamous cell carcinoma was successfully treated with irradiation of 4,000 rad and peplomycin of 60 mg intravenously given." | 1.27 | [Female urethral carcinoma: results of irradiation in 2 patients]. ( Kanai, S; Kondo, A; Miyake, K; Okamura, K; Otani, T; Sahashi, M; Saitoh, M; Sakakibara, T; Shimozi, T; Takashi, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gakis, G | 1 |
| Morgan, TM | 1 |
| Daneshmand, S | 1 |
| Keegan, KA | 1 |
| Todenhöfer, T | 1 |
| Mischinger, J | 1 |
| Schubert, T | 1 |
| Zaid, HB | 1 |
| Hrbacek, J | 1 |
| Ali-El-Dein, B | 1 |
| Clayman, RH | 1 |
| Galland, S | 1 |
| Olugbade, K | 1 |
| Rink, M | 1 |
| Fritsche, HM | 1 |
| Burger, M | 1 |
| Chang, SS | 1 |
| Babjuk, M | 1 |
| Thalmann, GN | 1 |
| Stenzl, A | 1 |
| Efstathiou, JA | 1 |
| Quinlan, JF | 1 |
| North, J | 1 |
| Clarke, DA | 1 |
| Gwynne-Jones, DP | 1 |
| Cohen, MS | 1 |
| Triaca, V | 1 |
| Billmeyer, B | 1 |
| Hanley, RS | 1 |
| Girshovich, L | 2 |
| Shuster, T | 1 |
| Oberfield, RA | 2 |
| Zinman, L | 1 |
| Lockhart, JL | 1 |
| Chaikin, L | 1 |
| Bondhus, MJ | 1 |
| Politano, VA | 1 |
| Lutz, ST | 1 |
| Huang, DT | 1 |
| Licht, MR | 1 |
| Klein, EA | 1 |
| Bukowski, R | 1 |
| Montie, JE | 1 |
| Saxton, JP | 1 |
| Zinman, LN | 1 |
| Leibenhaut, M | 1 |
| Silverman, ML | 1 |
| Solsona, E | 1 |
| Iborra, I | 1 |
| Ricós, JV | 1 |
| Monrós, JL | 1 |
| Dumont, R | 1 |
| Casanova, J | 1 |
| Calabuig, C | 1 |
| Saitoh, M | 1 |
| Kondo, A | 1 |
| Sakakibara, T | 1 |
| Takashi, M | 1 |
| Sahashi, M | 1 |
| Kanai, S | 1 |
| Okamura, K | 1 |
| Shimozi, T | 1 |
| Miyake, K | 1 |
| Otani, T | 1 |
| Johnson, DW | 1 |
| Kessler, JF | 1 |
| Ferrigni, RG | 1 |
| Anderson, JD | 1 |
| van Helsdingen, PJ | 1 |
| Rikken, CH | 1 |
| Shah, AB | 1 |
| Kalra, JK | 1 |
| Silber, L | 1 |
| Molho, L | 1 |
1 trial available for mitomycin and Cancer of the Urethra
| Article | Year |
|---|---|
Recurrence of superficial bladder tumors in prostatic urethra.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma in Si | 1991 |
11 other studies available for mitomycin and Cancer of the Urethra
| Article | Year |
|---|---|
Impact of perioperative chemotherapy on survival in patients with advanced primary urethral cancer: results of the international collaboration on primary urethral carcinoma.
Topics: Adenocarcinoma; Aged; Albumin-Bound Paclitaxel; Antineoplastic Combined Chemotherapy Protocols; Carb | 2015 |
Radiation-induced osteonecrosis of the hips following genital-preserving surgery and chemoradiotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arthroplasty, Replacement, Hip; Carcinoma, Squ | 2009 |
Coordinated chemoradiation therapy with genital preservation for the treatment of primary invasive carcinoma of the male urethra.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma; Cohort Studies; Combined Modality | 2008 |
Prostatic recurrences in the management of superficial bladder tumors.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Humans; Male; Middle Aged; M | 1983 |
Combined chemoradiotherapy for locally advanced squamous cell carcinoma of the bulbomembranous urethra: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; | 1995 |
Combination radiation and chemotherapy for the treatment of squamous cell carcinoma of the male and female urethra.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1995 |
Management of invasive squamous cell carcinoma of the bulbomembranous male urethra with co-ordinated chemo-radiotherapy and genital preservation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Squamous Cell; Comb | 1996 |
[Female urethral carcinoma: results of irradiation in 2 patients].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin | 1988 |
Low dose combined chemotherapy/radiotherapy in the management of locally advanced urethral squamous cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Comb | 1989 |
Treatment of urothelial carcinoma of the upper urinary tract following prostatocystectomy with mitomycin C instillation in the ileal loop.
Topics: Aged; Carcinoma, Transitional Cell; Combined Modality Therapy; Humans; Ileum; Kidney Neoplasms; Male | 1986 |
Squamous cell cancer of female urethra. Successful treatment with chemoradiotherapy.
Topics: Aged; Biopsy; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Female; Flu | 1985 |