Page last updated: 2024-11-06

mitomycin and Cancer of Sigmoid

mitomycin has been researched along with Cancer of Sigmoid in 17 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"From January 1980 to December 1986, 20 patients with adenocarcinoma of the sigmoid colon were treated with a 6 hours preoperative intra-arterial infusion of mitomycin-C followed by potentially curative surgery (Group A)."9.07Preoperative intra-arterial mitomycin-C in the management of sigmoid adenocarcinoma: long-term results of a pilot study. ( Campora, E; Cariati, A; De Caro, G; Fardelli, R; Gianquinto, D; Secco, GB; Sertoli, MR; Zoli, S, 1994)
"From January 1980 to December 1986, 20 patients with adenocarcinoma of the sigmoid colon were treated with a 6 hours preoperative intra-arterial infusion of mitomycin-C followed by potentially curative surgery (Group A)."5.07Preoperative intra-arterial mitomycin-C in the management of sigmoid adenocarcinoma: long-term results of a pilot study. ( Campora, E; Cariati, A; De Caro, G; Fardelli, R; Gianquinto, D; Secco, GB; Sertoli, MR; Zoli, S, 1994)
"Hemoptysis was negligible until he died 8 months later."1.32[Clinical benefit of bronchial arterial infusion chemotherapy to pulmonary metastasis from colorectal cancer--report of two cases]. ( Ishigaki, T; Kitai, T; Kojima, N; Miki, A; Nishikawa, S; Nomura, A; Todo, G; Ukikusa, M, 2003)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's5 (29.41)18.2507
2000's8 (47.06)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ochiai, T1
Maruyama, M1
Ebuchi, M1
Nagahama, T1
Takashima, I1
Hasegawa, K1
Natsui, S1
Sakoma, T1
Zeller, G1
Wandel, E1
Schwarting, A1
Kashiwazaki, M1
Mishima, H1
Takeda, Y1
Hasuike, Y1
Nishisyo, I1
Tsujinaka, T1
Kitai, T1
Nomura, A1
Miki, A1
Ukikusa, M1
Kojima, N1
Nishikawa, S1
Ishigaki, T1
Todo, G1
Burton, S1
Brown, G1
Daniels, I1
Norman, A1
Swift, I1
Abulafi, M1
Wotherspoon, A1
Tait, D1
Smolianskaia, AZ1
Spasibina, TV1
Takeda, S1
Hisatomi, K1
Nakano, S1
Okamoto, K1
Nagafuchi, Y1
Itoh, H1
Ohsato, K1
Secco, GB1
Fardelli, R1
Campora, E1
Sertoli, MR1
De Caro, G1
Cariati, A1
Zoli, S1
Gianquinto, D1
Masutani, S1
Kawasaki, T1
Ishida, H1
Kimura, F1
Okuyama, M1
Yamada, M1
Ishikawa, K1
Tatsuta, M1
Satomi, T1
Miura, M1
Terashima, Y1
Yamazaki, S1
Ikeyama, S1
Sasaki, K1
Taki, S1
Fukuda, Y1
Ishikawa, M1
Yogita, S1
Tashiro, S1
Musha, N1
Nihei, T1
Watanabe, N1
Sunami, E1
Sasaki, M1
Saito, H1
Sando, N1
Oka, K1
Nakagawa, K1
Suzuki, Y1
Toshima, T1
Momono, S1
Sasaki, Y1
Teshima, T1
Watanabe, O1
Haga, S1
Kato, H1
Ooishi, T1
Kobayashi, S1
Okabe, T1
Yoshimatsu, K1
Yokomizo, H1
Kumazawa, K1
Murayama, M1
Kajiwara, T1
Akaza, K1
Nonami, T1
Yasui, M1
Hashimoto, S1
Kurokawa, T1
Harada, A1
Nakao, A1
Takagi, H1
Smith, DE1
Muff, NS1
Shetabi, H1
Stutz, FH1
Eiesland, H1
Watase, M1
Iijima, S1
Umeshita, K1
Kanai, T1
Sakon, M1
Shimano, T1
Monden, M1
Okuda, H1
Okamura, J1
Mori, T1
Yasunaga, C1
Komota, T1
Mimura, K1
Kinjyo, M1
Sueishi, K1
Hirose, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neoadjuvant Chemoradiotherapy Versus Neoadjuvant Chemotherapy For Unresectable Locally Advanced Colon Cancer: An Open, Multi-centered, Randomize Controlled Phase 3 Trial.[NCT03970694]Phase 349 participants (Actual)Interventional2019-05-11Terminated (stopped due to Significant differences in conversion rate as well as R0 resection rate between the two groups.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for mitomycin and Cancer of Sigmoid

ArticleYear
Preoperative intra-arterial mitomycin-C in the management of sigmoid adenocarcinoma: long-term results of a pilot study.
    Tumori, 1994, Oct-31, Volume: 80, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Chemotherapy, Adjuvant; Female; Humans; Incidence; Infusions, Intra-Art

1994

Other Studies

16 other studies available for mitomycin and Cancer of Sigmoid

ArticleYear
[A case report of intra-hepatic arterial infusion of mitomycin C with degradable starch microspheres for liver metastases of sigmoid colon carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:12

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Biodegradation, Enviro

2002
[Mitomycin-induced hemolytic-uremic syndrome].
    Deutsche medizinische Wochenschrift (1946), 2003, Jun-20, Volume: 128, Issue:25-26

    Topics: Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Hemolytic-Uremic Syndrome; Hemorrhage; Humans;

2003
[A case of unresectable liver metastases from rectosigmoid colon cancer with survival for over 3 years after multidisciplinary treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Admini

2003
[Clinical benefit of bronchial arterial infusion chemotherapy to pulmonary metastasis from colorectal cancer--report of two cases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bronchial Arteries; Cisplatin; Colorectal Neoplasms;

2003
MRI identified prognostic features of tumors in distal sigmoid, rectosigmoid, and upper rectum: treatment with radiotherapy and chemotherapy.
    International journal of radiation oncology, biology, physics, 2006, Jun-01, Volume: 65, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2006
[Pharmacokinetics of mitomycin C in cancer patients during prolonged administration of the preparation].
    Antibiotiki, 1984, Volume: 29, Issue:5

    Topics: Breast Neoplasms; Female; Humans; Infusions, Parenteral; Kinetics; Mitomycin; Mitomycins; Neoplasms;

1984
A 10-year survivor with unresectable hepatic metastases from sigmoid colon carcinoma treated with regional chemotherapy.
    Surgery today, 1995, Volume: 25, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Hepatic Artery; Humans

1995
[A long-survival case of unresectable liver metastasis of colon cancer by hepatic arterial intermittent multidrug infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:13

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Doxoru

1994
[Secondary hepatic resections in a case of sigmoid colon cancer with multiple liver metastasis (H3) after successful continuous hepatic artery infusion chemotherapy oriented by in vitro chemosensitivity test].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:8

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug

1997
[Complete remission in a case of sigmoid colon cancer with multiple liver metastases-treatment with arterial chemotherapy and percutaneous microwave coagulation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Admi

2000
[A case of colonic cancer with multiple liver metastases effectively treated by intra-arterial chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:10

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Femal

2000
Case of liver metastasis from colon cancer successfully treated by regional chemotherapy with mitomycin C alone.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:2

    Topics: Antibiotics, Antineoplastic; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Mal

2002
[Two cases of esophageal varices complication after hepatic arterial infusion chemotherapy (HAI) for metastatic liver tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Esophageal and Gastric Varices; Female;

1992
Postoperative adjuvant chemotherapy and radiotherapy for cancer of the large bowel and rectum.
    American journal of surgery, 1989, Volume: 157, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cecal Neoplasms; Colonic Neop

1989
[A case of multiple liver metastases from sigmoid carcinoma treated successfully with arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:7

    Topics: Adenocarcinoma; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Dru

1986
[Microangiopathic hemolytic anemia (MAHA) observed after administration of mitomycin C (MMC)].
    Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:7

    Topics: Adenocarcinoma; Anemia, Hemolytic; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Postoperative C

1987