Page last updated: 2024-11-06

mitomycin and Cancer of Pancreas

mitomycin has been researched along with Cancer of Pancreas in 199 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"Gemcitabine-based chemotherapy is a commonly used first-line treatment for patients with pancreatic and biliary tract cancer."9.14Second-line treatment with a combination of continuous 5-fluorouracil, doxorubicin, and mitomycin-C (conti-FAM) in gemcitabine-pretreated pancreatic and biliary tract cancer. ( Jeong, JS; Kim, BG; Kim, HJ; Kim, SH; Kim, YH; Kwon, HC; Lee, S; Oh, SY; Rho, MH; Rho, MS, 2009)
"This study evaluates the maximum tolerated dose (MTD) and activity of mitomycin, docetaxel, and irinotecan (MDI) regimen on metastatic pancreatic adenocarcinoma, previously treated with gemcitabine-containing chemotherapy."9.11Salvage chemotherapy with mitomycin, docetaxel, and irinotecan (MDI regimen) in metastatic pancreatic adenocarcinoma: a phase I and II trial. ( Bonetto, E; Di Carlo, V; Nicoletti, R; Panucci, MG; Passoni, P; Reni, M; Ronzoni, M; Staudacher, C; Villa, E; Zerbi, A, 2004)
" The dose-limiting toxicities at the 160 mg/m2 gemcitabine level were myelosuppression, specifically neutropenia +/- thrombocytopenia, and gastrointestinal symptoms, including stomatitis, vomiting, and diarrhea."9.09Combined radiochemotherapy of locally advanced unresectable pancreatic adenocarcinoma with mitomycin C plus 24-hour continuous infusional gemcitabine. ( Kornek, GV; Kraus, G; Pötter, R; Rogy, M; Scheithauer, W; Schratter, A; Selzer, E; Ulrich-Pur, H, 2001)
"In a randomized trial we compared single-agent epirubicin with the FEM (5-fluorouracil/epirubicin/mitomycin) combination in patients with locally advanced and/or metastatic adenocarcinoma of the pancreas."9.07Comparison of single-agent epirubicin and 5-fluorouracil/epirubicin/mitomycin in patients with advanced adenocarcinoma of the pancreas. ( Coombes, RC; Glees, J; Topham, C, 1993)
"Twenty-two patients with inoperable adenocarcinoma of the pancreas were treated with 5-fluorouracil (5-FU), mitomycin C (Mito-C), and 1(-2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (MeCCNU)."9.06Activity of 5-fluorouracil, mitomycin C, and methyl CCNU in inoperable adenocarcinoma of pancreas. ( Chapman, J; Chinn, B; Groshko, G; Maniscalco, B; Piper, D; Reznik, S; Vaughn, C; Ward, D, 1989)
"Twenty-nine patients with advanced adenocarcinoma of the pancreas were treated with a combination of mitomycin-C, 5-fluorouracil, and adriamycin (MIFA III)."9.05MIFA III (mitomycin-C, 5-fluorouracil, and adriamycin) chemotherapy for advanced adenocarcinoma of the pancreas. ( Cheng, EW; Magill, GB; Sordillo, PP; Sternberg, CN, 1984)
"To report the effect of regional combination chemotherapy in a cohort of patients with inoperable pancreatic carcinoma treated with or without low-dose warfarin."7.73Effects of low-dose warfarin and regional chemotherapy on survival in patients with pancreatic carcinoma. ( Löhr, M; Müller, H; Nakchbandi, IA; Nakchbandi, W; Singer, MV, 2006)
"Dipyridamole 75 mg was administered orally three times daily during the FU administration."6.73Phase II trial of infusional fluorouracil, leucovorin, mitomycin, and dipyridamole in locally advanced unresectable pancreatic adenocarcinoma: SWOG S9700. ( Barstis, JJ; Bendetti, JK; Isacoff, WH; Jazieh, AR; Macdonald, JS; Philip, PA, 2007)
"Gemcitabine-based chemotherapy is a commonly used first-line treatment for patients with pancreatic and biliary tract cancer."5.14Second-line treatment with a combination of continuous 5-fluorouracil, doxorubicin, and mitomycin-C (conti-FAM) in gemcitabine-pretreated pancreatic and biliary tract cancer. ( Jeong, JS; Kim, BG; Kim, HJ; Kim, SH; Kim, YH; Kwon, HC; Lee, S; Oh, SY; Rho, MH; Rho, MS, 2009)
"In contrast to earlier reports HAP and CAI with MMC and Melphalan did not demonstrate any benefit in terms of tumour response, median survival and pain reduction, compared to less invasive treatment options."5.11Balloon catheter hypoxic abdominal perfusion with Mitomycin C and Melphalan for locally advanced pancreatic cancer: a phase I-II trial. ( de Bruijn, EA; Eggermont, AM; Guetens, G; Jeekel, J; ten Hagen, TL; van Eijck, CH; van Etten, B; van IJken, MG, 2004)
"This study evaluates the maximum tolerated dose (MTD) and activity of mitomycin, docetaxel, and irinotecan (MDI) regimen on metastatic pancreatic adenocarcinoma, previously treated with gemcitabine-containing chemotherapy."5.11Salvage chemotherapy with mitomycin, docetaxel, and irinotecan (MDI regimen) in metastatic pancreatic adenocarcinoma: a phase I and II trial. ( Bonetto, E; Di Carlo, V; Nicoletti, R; Panucci, MG; Passoni, P; Reni, M; Ronzoni, M; Staudacher, C; Villa, E; Zerbi, A, 2004)
" The dose-limiting toxicities at the 160 mg/m2 gemcitabine level were myelosuppression, specifically neutropenia +/- thrombocytopenia, and gastrointestinal symptoms, including stomatitis, vomiting, and diarrhea."5.09Combined radiochemotherapy of locally advanced unresectable pancreatic adenocarcinoma with mitomycin C plus 24-hour continuous infusional gemcitabine. ( Kornek, GV; Kraus, G; Pötter, R; Rogy, M; Scheithauer, W; Schratter, A; Selzer, E; Ulrich-Pur, H, 2001)
"In a randomized trial we compared single-agent epirubicin with the FEM (5-fluorouracil/epirubicin/mitomycin) combination in patients with locally advanced and/or metastatic adenocarcinoma of the pancreas."5.07Comparison of single-agent epirubicin and 5-fluorouracil/epirubicin/mitomycin in patients with advanced adenocarcinoma of the pancreas. ( Coombes, RC; Glees, J; Topham, C, 1993)
"One hundred thirty-three patients with advanced pancreatic adenocarcinoma and measurable disease were treated with 5-fluorouracil (5-FU) plus doxorubicin plus mitomycin C (FAM), streptozotocin plus mitomycin C plus 5-FU (SMF) in the regimen originally reported, and streptozotocin plus mitomycin C plus 5-FU with 5-FU and streptozotocin administered in five-day courses."5.06Phase II studies of drug combinations in advanced pancreatic carcinoma: fluorouracil plus doxorubicin plus mitomycin C and two regimens of streptozotocin plus mitomycin C plus fluorouracil. The Gastrointestinal Tumor Study Group. ( , 1986)
"One hundred eighty-seven patients with histologically proven advanced pancreatic adenocarcinoma were randomly assigned to therapy with 5-fluorouracil (5-FU) alone, to the Mallinson regimen (combined and sequential 5-FU, cyclophosphamide, methotrexate, vincristine, and mitomycin C), or to combined 5-FU, doxorubicin, and cisplatin (FAP)."5.06A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin. ( Barlow, JF; Cullinan, S; Foley, JF; Kardinal, CG; Krook, JE; Moertel, CG; Norris, BD; Schutt, AJ; Tschetter, LK; Wieand, HS, 1990)
"Twenty-two patients with inoperable adenocarcinoma of the pancreas were treated with 5-fluorouracil (5-FU), mitomycin C (Mito-C), and 1(-2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (MeCCNU)."5.06Activity of 5-fluorouracil, mitomycin C, and methyl CCNU in inoperable adenocarcinoma of pancreas. ( Chapman, J; Chinn, B; Groshko, G; Maniscalco, B; Piper, D; Reznik, S; Vaughn, C; Ward, D, 1989)
"Twenty-nine patients with advanced adenocarcinoma of the pancreas were treated with a combination of mitomycin-C, 5-fluorouracil, and adriamycin (MIFA III)."5.05MIFA III (mitomycin-C, 5-fluorouracil, and adriamycin) chemotherapy for advanced adenocarcinoma of the pancreas. ( Cheng, EW; Magill, GB; Sordillo, PP; Sternberg, CN, 1984)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"We aimed to evaluate the efficacy and safety of 5-fluorouracil-based neoadjuvant chemoradiotherapy (NACRT) in patients with resectable/borderline resectable pancreatic ductal adenocarcinoma (PDAC)."3.91Efficacy and safety of preoperative 5-fluorouracil, cisplatin, and mitomycin C in combination with radiotherapy in patients with resectable and borderline resectable pancreatic cancer: a long-term follow-up study. ( Abe, Y; Aiura, K; Endo, Y; Fukada, J; Hori, S; Itano, O; Kitagawa, Y; Kitago, M; Masugi, Y; Nakano, Y; Oshima, G; Shinoda, M; Yagi, H, 2019)
"In patients with known BRCA 1 or 2 mutation-associated pancreatic adenocarcinoma, the addition of a DNA cross-linking agent such as cisplatin, oxaliplatin, or mitomycin to a standard gemcitabine chemotherapy backbone should be considered."3.77A 67-year-old woman with BRCA 1 mutation associated with pancreatic adenocarcinoma. ( Drukker, L; Epstein, A; Gabizon, A; Isacson, R; Keinan, A; Kelsen, D; Lowery, M; O'Reilly, EM; Rachkiman, M; Reissman, P; Rosengarten, O; Segal, A; Shah, MA; Smyth, E, 2011)
"For patients with locally advanced gastric cancer, combined-modality therapy has resulted in long-term survival for approximately 15% of cases."3.75The role of chemotherapy in the management of gastric and pancreatic carcinomas. ( Schein, PS, 1985)
"To report the effect of regional combination chemotherapy in a cohort of patients with inoperable pancreatic carcinoma treated with or without low-dose warfarin."3.73Effects of low-dose warfarin and regional chemotherapy on survival in patients with pancreatic carcinoma. ( Löhr, M; Müller, H; Nakchbandi, IA; Nakchbandi, W; Singer, MV, 2006)
"(1) To determine the toxicity of an intensified postoperative adjuvant regimen for periampullary adenocarcinoma (pancreatic and nonpancreatic) utilizing concurrent 5-fluorouracil (5-FU), leucovorin (LV), dipyridamole (DPM), and mitomycin-C (MMC) combined with split-course locoregional external beam radiotherapy (EBRT) to 50 Gy."3.70Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival. ( Abrams, RA; Cameron, JL; Chakravarthy, A; Donehower, RC; Grochow, LB; Hruban, RH; Hurwitz, H; Jaffee, EM; Korman, LT; Lillemoe, KD; O'Reilly, S; Yeo, CJ; Zahurek, ML, 2000)
"From November 1983 to January 1993, 30 patients with pancreatic adenocarcinoma including 9 with carcinoma of the body and tail were treated by a multimodal approach consisting of extended pancreatectomy, intraoperative radiotherapy (IORT), and hepatic artery or portal vein infusion of mitomycin C (MMC) followed by systemic bolus injection."3.70Long-term survival after multimodality treatment for resectable pancreatic cancer. ( Fukushima, N; Kinoshita, T; Kosuge, T; Mukai, K; Ozaki, H; Shimada, K; Tokuuye, K; Yamamoto, J, 2000)
"In order to determine whether preresectional chemoradiotherapy (CTRT) would influence resectability, local control, and survival of patients with localized pancreatic adenocarcinoma, a 5 1/2-year prospective study of 39 patients treated with preoperative radiation therapy, 5-Fluorouracil (5-FU), and Mitomycin C has been performed."3.68A single institutional experience with preoperative chemoradiotherapy for stage I-III pancreatic adenocarcinoma. ( Agarwal, P; Eisenberg, BL; Engstrom, P; Hoffman, JP; Litwin, S; Paul, AR; Scher, R; Solin, LJ; Watts, P; Weese, JL, 1993)
"We investigated the antitumor effects of intratumoral (IT) injection of mitomycin-C (MMC), 5-fluorouracil (5FU), adriamycin (ADR), cisplatin (CDDP), streptozotocin (STZ), and interleukin-2 (IL-2) on well-differentiated pancreatic ductal adenocarcinoma (WD PaCa), a solid tumor model in the Syrian golden hamster."3.68Experimental study on multidisciplinary treatment of pancreatic cancer. ( Makino, I; Moriai, T; Takeba, T, 1990)
" In our previous studies with human gastrointestinal and breast cancers xenografted into nude mice, combination therapy with mitomycin C (MMC) and 5'-deoxy-5-fluorouridine (5'-DFUR) [I] or cisplatin (CDDP), vindesine (VDS) and 5'-DFUR [II] produced higher response rates than single-agent therapy with any one of these drugs."3.67[Effects of alternating chemotherapy with 2 non-cross-resistant drug combinations on human alimentary and breast cancer xenografts in nude mice]. ( Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T; Yamauchi, T, 1987)
"Hexamethylmelamine, mitomycin C and 5-fluorouracil infusion (HexMF) achieved a median survival of 9 months for the 45 patients with either metastatic stage III or unresectable stage II carcinoma of the pancreas."3.67Primary treatment of regional and disseminated pancreatic cancer with hexamethylmelamine, mitomycin C and 5-fluorouracil infusion. ( Bruckner, HW; Butwell, N; Gorbaty, MI; Kalman, J; McKenna, A; Spigelman, M; Storch, J, 1989)
"A 55-year-old female, in which an unresectable Borrmann II-type gastric cancer (moderately differentiated adenocarcinoma) extending from vicinity of the cardia to the lower portion of the corpus, with direct invasion into the pancreas and extensive lymph node metastases, confirmed by laparotomy, was treated postoperatively by 3 courses of chemotherapy with cisplatinum in combination with mitomycin C and 5-fluorouracil."3.67Cure of advanced gastric cancer by combined chemotherapy with cisplatinum, mitomycin C, and 5-fluorouracil. ( Azuma, S; Furuta, T; Kawata, R; Ohashi, H; Saji, S; Sakata, K; Shimokawa, K; Suzuki, M; Tanemura, H, 1988)
"Nineteen patients with unresectable and metastatic adenocarcinoma of the pancreas and ampulla of Vater were treated with intermittent regional infusion of the celiac axis (CAI) with the combination of 5-fluorouracil, adriamycin, mitomycin-C, and streptozotocin (FAM-S)."3.66Intermittent regional infusion of chemotherapy for pancreatic adenocarcinoma. Phase I and II pilot study. ( Bukowski, RM; Hewlett, JS; Livingston, RB; Theodors, A; Weick, JK, 1982)
"In gemcitabine-pretreated pancreatic cancer, salvage chemotherapy has not been established, and the prognostic factors are not completely known."2.76Efficacy of infusional 5-fluorouracil, doxorubicin, and mitomycin-C (iFAM) in the treatment of patients with gemcitabine-pretreated pancreatic cancer and analysis of prognostic factors in a salvage setting. ( Bang, YJ; Han, SW; Im, SA; Kim, TY; Lee, KH; Lim, KH; Oh, DY, 2011)
"Once developed, the progression of pancreatic cancer metastasis is virtually unstoppable with current therapies."2.76Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer. ( De Jesus-Acosta, A; Donehower, R; Eshleman, JR; Garrido-Laguna, I; Hidalgo, M; Hruban, RH; Jones, S; Klein, A; Laheru, D; Maitra, A; Rajeshkumar, NV; Villarroel, MC, 2011)
" Main adverse events grades 2/3/4 were (n): leukocytopenia 3/2/2, anemia 13/4/0, thrombocytopenia 3/1/0, nausea/vomiting 2/1/0, diarrhea 5/1/0, hand-foot-skin reaction 7/0/0."2.75Efficacy and safety of capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated pancreatic, gallbladder, and bile duct carcinoma. ( Ernst, T; Hochhaus, A; Hofheinz, RD; Hofmann, WK; Kripp, M; Kruth, J; Lukan, N; Merx, K; Nissen, J, 2010)
"The incidence of liver metastasis in group A was 34% which was lower than 50% in group B."2.74Effect of multiple-phase regional intra-arterial infusion chemotherapy on patients with resectable pancreatic head adenocarcinoma. ( Fu, DL; Jin, C; Long, J; Ni, QX; Xu, J; Yang, F; Yao, L; Yu, XJ, 2009)
"Dipyridamole 75 mg was administered orally three times daily during the FU administration."2.73Phase II trial of infusional fluorouracil, leucovorin, mitomycin, and dipyridamole in locally advanced unresectable pancreatic adenocarcinoma: SWOG S9700. ( Barstis, JJ; Bendetti, JK; Isacoff, WH; Jazieh, AR; Macdonald, JS; Philip, PA, 2007)
"Mitomycin C (MMC) in combination with infusional 5-fluorouracil (FU) plus folinic acid (FA) is an effective treatment for metastatic gastrointestinal cancer."2.71Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer. ( Gnad, U; Hartmann, JT; Hehlmann, R; Hochhaus, A; Hofheinz, RD; Kreil, S; Saussele, S; Weisser, A; Willer, A, 2004)
"Because of the poor response of pancreatic cancer to conventional therapy, the authors performed a phase II pilot study to evaluate whether beta-interferon and retinoids, added to active chemotherapeutic agents, could increase response rate and survival in a group of patients who had metastatic disease."2.69Advanced carcinoma of the pancreas: phase II study of combined chemotherapy, beta-interferon, and retinoids. ( Casucci, D; Frati, L; Gulino, A; Rea, S; Recchia, F; Sica, G, 1998)
"Patterns of failure reveal that pancreatic cancer involves three compartments: the pancreatic bed and regional lymph nodes, the liver and the peritoneal surfaces."2.68Regional chemotherapy for inoperable pancreatic carcinoma. ( George, WJ; Muchmore, JH; Preslan, JE, 1996)
"Most pancreatic cancers cannot be resected at the time of diagnosis."2.67[Chemotherapy of cancer of the exocrine pancreas]. ( Bonneterre, J, 1990)
"Preoperative chemoradiation for cancer of the pancreas and duodenal region was relatively well-tolerated and enhanced resectability and downstaging of nodal metastases were suggested."2.67Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum. ( Coia, L; Eisenberg, B; Hanks, G; Hoffman, J; Paul, A; Scher, R; Solin, L; Weese, J; Weiner, L, 1994)
" Despite its pharmacokinetic advantages, the aortic stop flow technique is currently not recommendable for routine use."2.43Pharmacokinetics of the antineoplastic drug mitomycin C in regional chemotherapy using the aortic stop flow technique in advanced pancreatic carcinoma. ( Gebauer, T; Grote, R; Lippert, H; Martens-Lobenhoffer, J; Meyer, F; Ridwelski, K, 2005)
"Patients with pancreatic cancer are treated with combined treatment modalities."2.42[The update on pancreatic cancer chemotherapy]. ( Brasiūnas, V; Brasiūniene, B; Inciūra, A; Juozaityte, E, 2003)
"It is well-known that the patients with pancreatic cancer are vulnerable for recurrence such as local relapse and liver metastasis after surgical resection."2.40[Therapeutic strategy for the recurrence of pancreatic cancer following pancreatectomy]. ( Egawa, S; Kobari, M; Matsuno, S; Shibuya, K; Shimamura, H; Sunamura, M; Takeda, K, 1999)
"For Dukes' C colon cancer, postoperative adjuvant chemotherapy with a combination of fluorouracil and levamisole is now recommended as standard therapy."2.39Adjuvant postoperative therapy of gastrointestinal malignancies. ( Ilson, DH; Kelsen, DP, 1994)
"In advanced pancreatic cancer, chemotherapy has no curative potential, and the goal is to palliate symptoms or delay their onset so as to improve the quality of life of patients."2.38[Chemotherapy for advanced pancreatic carcinoma]. ( Shimada, Y; Yokoyama, T, 1992)
"The effectiveness of MMC against human stomach cancers xenografted to nude mice clearly correlated to the clinical effect of MMC against gastric cancer."2.37[Recent advanced studies on mitomycins, antitumor activity and mode of action]. ( Morimoto, M; Taguchi, T, 1987)
"Gemcitabine and cisplatin were each capable of activating MK2, and we did not observe differences in the intracellular localization of MK2 upon treatment."1.48Inhibition of MAPKAPK2/MK2 facilitates DNA replication upon cancer cell treatment with gemcitabine but not cisplatin. ( Dobbelstein, M; Köpper, F; Li, Y, 2018)
"Olaparib had substantial toxicity when combined with IC or ICM in patients with PDAC, and this treatment combination did not have an acceptable risk/benefit profile for further study."1.46Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer. ( Azad, NS; De Jesus-Acosta, A; Donehower, RC; Fine, RL; Goggins, M; Jaffee, EM; Johnson, BA; Laheru, DA; Le, DT; Myzak, MC; Oberstein, PE; Yarchoan, M; Zheng, L, 2017)
"Thrombocytopenia was the most frequently observed grade 4 toxicity in both groups (11% after FM versus 12% after GC)."1.37Gemcitabine/cisplatin versus 5-fluorouracil/mitomycin C chemoradiotherapy in locally advanced pancreatic cancer: a retrospective analysis of 93 patients. ( Brunner, TB; Fietkau, R; Sauer, R, 2011)
"We retrospectively assessed the benefits of 5-fluorouracil (5-FU)- and heparin-based portal infusion chemotherapy combined with systemic administration of mitomycin C (MMC) and cisplatin (CDDP) for 4 weeks following surgery (PI4W)."1.36Beneficial effects of 5-Fluorouracil and heparin-based portal infusion chemotherapy combined with mitomycin C and cisplatin after curative resection of pancreatic cancer. ( Aiura, K; Kitagawa, Y; Matsui, J; Takahashi, S; Ueda, M, 2010)
"Nonfunctioning islet cell tumor of the pancreas is frequently found in young female."1.34[Management of nonfunctioning islet cell tumors of the pancreas]. ( Ding, XW; Hao, XS; Liang, H; Pan, Y; Wang, BG; Wang, XN, 2007)
"Two retrovirally complemented pancreatic cancer cell lines having defects in the Fanconi anemia pathway, PL11 (FANCC-mutated) and Hs766T (FANCG-mutated), as well as several parental pancreatic cancer cell lines with or without mutations in the Fanconi anemia/BRCA2 pathway, were assayed for in vitro and in vivo sensitivities to various chemotherapeutic agents."1.33In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor. ( Brody, JR; Cunningham, SC; DeMarzo, AM; Dezentje, DA; Gallmeier, E; Hruban, RH; Isacoff, WH; Kern, SE; Offerhaus, GJ; Swartz, MJ; van der Heijden, MS, 2005)
"A patient with liver metastasis of pancreatic cancer received chemotherapy using mitomycin C and degradable starch microspheres."1.32Liver metastasis of pancreatic cancer managed by intra-arterial infusion chemotherapy combined with degradable starch microspheres. ( Aoki, T; Kato, F; Katsumata, K; Koyanagi, Y; Sumi, T; Suzuki, Y; Takagi, M; Tomioka, H; Yamasaki, T, 2003)
"The use of neoadjuvant chemotherapy for pancreatic cancer has been advocated for its potential ability to optimize patient selection for surgical resection and to downstage locally advanced tumors, especially for patients with Stage IV b (Japan criteria)."1.32[Adjuvant chemotherapy for unresectable locally advanced pancreatic cancer in light of its characteristics]. ( Hirano, H; Ikuma, H; Imai, T; Kadowaki, S; Mitsui, Y; Miyashita, K; Murata, T; Nakamura, T; Nobuoka, Y; Tanigawa, K; Taoka, H; Umino, W; Yamashita, M; Yoshimine, S, 2004)
"In patients with pancreatic cancer, the overall response rate was 42% with a median survival of 8 months."1.31Irinotecan, cisplatin and mitomycin in inoperable gastro-oesophageal and pancreatic cancers - a new active regimen. ( Gallagher, CJ; Shamash, J; Slater, S; Slevin, ML; Wilson, P, 2002)
"Our experience of arterial infusion chemotherapy combined with regional hyperthermia in the treatment of non-resectable pancreatic cancer was presented."1.31[Intra-arterial infusion chemotherapy in combination with microwave hyperthermia for cancer of head of pancreas and liver metastasis--a case of 16 years survival]. ( Endo, Y; Ikeda, H; Matumoto, Y; Miura, T, 2000)
"With gastric cancer, however, there was no significant difference."1.31[Hepatic arterial infusion chemotherapy for unresectable liver metastasis of gastrointestinal cancers]. ( Hirakawa, K; Nishino, H; Ohira, M; Shimizu, S; Tamamori, Y; Tanaka, H; Yamada, N, 2000)
"Gemcitabine treatment appeared most effective."1.31[Experience with chemotherapy for advanced pancreatic carcinoma]. ( Gershanovich, ML; Ignashov, AM; Ivanova, NE; Kokhanenko, NIu; Osipenko, SK; Rybakov, GV, 2000)
"We treated a case of unresectable gastric cancer in which peritoneal lavage cytology and the primary tumor responded to combined chemotherapy by intravenous, intraarterial and intraperitoneal injection."1.31[A case of stage IV gastric cancer responding to combined chemotherapy by intravenous, intraarterial and intraperitoneal injection]. ( Hattori, T; Hirano, K; Kase, H; Kobayashi, K; Ogawa, M; Teramoto, T; Tokura, N; Washizawa, N, 2000)
" Compared with the cell necrosis, the dosage of drugs was less and the time was shorter for inducing apoptosis."1.30[Apoptosis of human pancreatic carcinoma cell lines induced by combinations of chemotherapeutic drugs]. ( Cai, L; Liao, Q; Wu, Y; Zhao, Y; Zhu, Y, 1999)
"In a patient with advanced pancreatic cancer, with a hypercoagulable state, a complete clinical response was obtained with a mitomycin-based regimen plus adjunctive heparin."1.30Complete clinical remission in a patient with advanced pancreatic cancer using mitomycin C-based chemotherapy: the role of adjunctive heparin. ( Latino, F; Sadoff, L, 1999)
"Chemotherapy for pancreatic cancer does not satisfactorily improve prognosis."1.29In vitro chemosensitivity of human pancreatic cancer cell lines. ( Oka, T; Sawabe, Y; Yamagishi, H; Yamaguchi, N; Yamamura, Y, 1996)
"A case of unresectable pancreatic cancer in a 76-year-old female was reported, in which a tumor had liver involvement."1.29[A case of pancreatic cancer surviving for 7 years 11 months following intra-arterial and portal infusion chemotherapy]. ( Endo, T; Ichikawa, J; Ishii, H; Kenmotsu, M; Tsunemitsu, K, 1995)
"Pancreatic cancer is a disease with essentially no effective treatment."1.29A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice. ( Furukawa, T; Hoffman, RM; Kitajima, M; Kubota, T; Watanabe, M, 1993)
"The current treatment of pancreatic cancer with resection and/or radiation is considered unsatisfactory because of a high incidence of failure and a moderate incidence of complications."1.28Isolated perfusion of pancreas with mitomycin C. ( Arredondo, MA; Chaudhuri, B; Chaudhuri, PK; Crist, KA; Kar, R; Thomford, NR, 1990)
"Nineteen patients with resectable pancreatic cancer have been treated by a multidisciplinary approach at the National Cancer Center Hospital."1.28Evidence of effective multidisciplinary treatment for resectable pancreatic cancer from the viewpoint of the CA19-9 level. ( Egawa, S; Kinoshita, T; Kosuge, T; Ozaki, H; Shimada, K; Yamamoto, J, 1991)
"These consisted of four gastric cancers (H-55, H-111, H-81 and H-154), one breast cancer (H-31) and one pancreatic cancer (H-48)."1.28[Combination chemotherapy of HO-221, a derivative of benzoylphenylurea with various anticancer agents against human cancer xenografts in nude mice]. ( Fujita, F; Fujita, M; Inaba, H; Okuyama, Y; Sugimoto, T; Taguchi, T, 1991)
"Four patients with unresectable pancreatic cancer and one with metastatic liver tumor after curative pancreatic resection for carcinoma of the pancreas had undergone intra-arterial infusion chemotherapy using an implantable drug delivery system."1.28[Long-term arterial infusion chemotherapy in unresectable pancreatic cancer]. ( Asamura, M; Kakizaki, K; Kikuti, H; Takahashi, N; Yamauchi, H, 1989)
" The portal concentration of MMC increased rapidly to the maximum concentration of 826 +/- 364 ng/ml at 5 minutes after administration, when the dosage was 20 mg (four cases)."1.28[Portal blood levels of mitomycin C after intraperitoneal administration]. ( Kakizaki, K; Yamada, Y; Yamauchi, H, 1992)
"Fourty eight patients with cancer of head of pancreas have been treated by the intra-arterial infusion of 5-FU and Mitomycin C alone or in combination with regional hyperthermia, employing microwave machine operating at a frequency of 2450 MHz."1.27[Hyperthermia: microwave hyperthermia in combination with intra-arterial infusion chemotherapy of cancer of the pancreas]. ( Endo, Y; Funatomi, H; Hatta, Y; Hirose, N; Miura, T; Sassa, T; Taguchi, S; Yoshikawa, N, 1985)
"A woman with pancreatic cancer developed acute interstitial infiltrates while receiving modest doses of two potential pulmonary toxins, mitomycin-C and chlorozotocin."1.27Combination chemotherapy pneumonitis: a case report of possible synergistic toxicity. ( Goedert, JJ; Smith, FP; Tsou, E; Weiss, RB, 1983)
"The sensitivity of two human pancreatic adenocarcinomas (Capan-1 and Capan-2) to heat and heat combined with chemotherapy was studied using xenografts of the tumors in the foot of athymic nude mice."1.27Sensitivity of xenografts of human pancreatic adenocarcinoma in nude mice to heat and heat combined with chemotherapy. ( Cahan, A; Fogh, J; Fortner, JG; Shiu, MH, 1983)
"The incidence of pancreatic cancer has been increasing in recent years."1.27[Chemotherapy of pancreatic cancer]. ( Nakamura, K; Ozaki, H; Tajiri, H; Yoshimori, M, 1985)

Research

Studies (199)

TimeframeStudies, this research(%)All Research%
pre-199063 (31.66)18.7374
1990's61 (30.65)18.2507
2000's54 (27.14)29.6817
2010's20 (10.05)24.3611
2020's1 (0.50)2.80

Authors

AuthorsStudies
Endo, Y3
Kitago, M1
Aiura, K2
Shinoda, M1
Yagi, H1
Abe, Y1
Oshima, G1
Hori, S1
Nakano, Y1
Itano, O1
Fukada, J1
Masugi, Y1
Kitagawa, Y2
Yarchoan, M1
Myzak, MC1
Johnson, BA1
De Jesus-Acosta, A2
Le, DT1
Jaffee, EM2
Azad, NS1
Donehower, RC2
Zheng, L1
Oberstein, PE1
Fine, RL1
Laheru, DA1
Goggins, M1
Li, Y1
Köpper, F1
Dobbelstein, M1
Farshid, P1
Darvishi, A1
Naguib, N1
Bazrafshan, B1
Paul, J1
Mbalisike, E1
Vogl, TJ3
Mezencev, R1
Wang, L1
Xu, W1
Kim, B1
Sulchek, TA1
Daneker, GW1
McDonald, JF1
Drudi, F1
Tassinari, D1
Giuliani, J1
Ridolfi, C1
Gianni, L1
Tamburini, E1
Fantini, M1
Santelmo, C1
Barzotti, E1
Lotti, N1
Ravaioli, A1
Heinrich, S4
Kraft, D1
Staib-Sebler, E4
Schwarz, W2
Gog, C4
Vogl, T1
Lorenz, M4
Vyas, O1
Leung, K1
Ledbetter, L1
Kaley, K1
Rodriguez, T1
Garcon, MC1
Saif, MW2
Yoshioka, M1
Shibata, S1
Uchinami, H1
Watanabe, G3
Miyazawa, H1
Iida, M1
Yoshida, M1
Yoshioka, T1
Nanjo, H1
Yamamoto, Y1
Lal, S1
Zarei, M1
Chand, SN1
Dylgjeri, E1
Mambelli-Lisboa, NC1
Pishvaian, MJ1
Yeo, CJ2
Winter, JM1
Brody, JR4
Nakchbandi, W2
Müller, H2
Singer, MV2
Lohr, JM1
Nakchbandi, IA2
Jin, C1
Yao, L1
Long, J1
Fu, DL1
Yu, XJ1
Xu, J1
Yang, F1
Ni, QX1
Dezentje, DA3
Arking, DE1
Kortenhorst, MS1
West, K1
Chakravarti, A1
Kern, SE4
Yoshizawa, J1
Takizawa, A1
Takeuchi, O1
Hiraku, O1
Sasaki, K1
Morimoto, Y1
Atsuda, K1
Inoue, G1
Suzuki, Y2
Asanuma, F1
Yamada, Y4
Lee, S1
Oh, SY1
Kim, BG1
Kwon, HC1
Kim, SH1
Rho, MH1
Kim, YH1
Rho, MS1
Jeong, JS1
Kim, HJ1
Kruth, J1
Nissen, J1
Ernst, T1
Kripp, M1
Lukan, N1
Merx, K1
Hofmann, WK1
Hochhaus, A2
Hofheinz, RD2
Dai, T1
Takahashi, S1
Matsui, J1
Ueda, M1
Lowery, M1
Shah, MA1
Smyth, E1
Epstein, A1
Segal, A1
Rosengarten, O1
Isacson, R1
Drukker, L1
Keinan, A1
Rachkiman, M1
Reissman, P1
Gabizon, A2
Kelsen, D1
O'Reilly, EM1
Villarroel, MC1
Rajeshkumar, NV1
Garrido-Laguna, I1
Jones, S1
Maitra, A1
Hruban, RH4
Eshleman, JR1
Klein, A1
Laheru, D1
Donehower, R1
Hidalgo, M1
Lim, KH1
Kim, TY2
Lee, KH1
Han, SW1
Oh, DY1
Im, SA1
Bang, YJ1
Cereda, S1
Reni, M2
Rognone, A1
Fugazza, C1
Ghidini, M1
Ceraulo, D1
Brioschi, M1
Nicoletti, R2
Villa, E2
Brunner, TB1
Sauer, R2
Fietkau, R2
Amitay, Y1
Tzemach, D1
Gorin, J1
Shmeeda, H1
Zalipsky, S1
Cui, S1
Ba, M1
Tang, Y1
Liu, J1
Wu, Y2
Wang, B1
Zhang, X1
Tang, H1
Zhong, S1
Maisey, N1
Chau, I1
Cunningham, D2
Norman, A2
Seymour, M1
Hickish, T1
Iveson, T1
O'Brien, M1
Tebbutt, N1
Harrington, A1
Hill, M2
Slater, S1
Shamash, J1
Wilson, P1
Gallagher, CJ1
Slevin, ML1
Liao, Q2
Zhao, Y2
Cai, L1
Zhu, Y1
Ji, Z1
Wang, Y1
Chen, X1
Wu, T1
Katsumata, K1
Tomioka, H1
Sumi, T1
Yamasaki, T1
Takagi, M1
Kato, F1
Aoki, T2
Koyanagi, Y1
Heller, M2
Zangos, S2
Eichler, K1
Mack, MG1
Berger, D1
Balzer, JO1
Kelleher, M1
Tebbutt, NC1
Andreyev, J1
Allen, M1
LANGDON, EA1
OTTOMAN, RE1
ROCHLIN, DB1
SMART, CR1
MYHRE, K1
FJAERLI, J1
SULLIVAN, RD1
ZUREK, WZ1
Brasiūniene, B1
Juozaityte, E1
Brasiūnas, V1
Inciūra, A1
Varrassi, G1
Guadagni, S3
Ciccozzi, A1
Marinangeli, F1
Pozone, T1
Piroli, A1
Marsili, I1
Paladini, A1
Van Der Heijden, MS3
Willer, A1
Weisser, A1
Gnad, U1
Saussele, S1
Kreil, S1
Hartmann, JT1
Hehlmann, R1
Tuinmann, G1
Hegewisch-Becker, S1
Zschaber, R1
Kehr, A1
Schulz, J1
Hossfeld, DK1
van IJken, MG2
van Etten, B1
Guetens, G1
ten Hagen, TL1
Jeekel, J2
de Bruijn, EA1
Eggermont, AM2
van Eijck, CH2
Gallmeier, E2
Cunningham, SC2
Shen, D1
Sasson, AR1
Wetherington, RW1
Hoffman, JP3
Ross, EA1
Cooper, H1
Meropol, NJ1
Freedman, G1
Pingpank, JF1
Eisenberg, BL3
Taoka, H1
Hirano, H1
Mitsui, Y1
Umino, W1
Nobuoka, Y1
Yamashita, M1
Tanigawa, K1
Yoshimine, S1
Imai, T1
Kadowaki, S1
Miyashita, K1
Ikuma, H1
Nakamura, T1
Murata, T1
Panucci, MG1
Passoni, P1
Bonetto, E1
Ronzoni, M1
Zerbi, A1
Staudacher, C1
Di Carlo, V1
Meyer, F1
Ridwelski, K1
Gebauer, T1
Grote, R1
Martens-Lobenhoffer, J1
Lippert, H1
Mizuta, Y1
Akazawa, Y1
Shiozawa, K1
Ohara, H1
Ohba, K1
Ohnita, K1
Isomoto, H1
Takeshima, F1
Omagari, K1
Tanaka, K1
Yasutake, T1
Nakagoe, T1
Shirono, K1
Kohno, S1
Cohen, SJ1
Dobelbower, R1
Lipsitz, S1
Catalano, PJ1
Sischy, B1
Smith, TJ1
Haller, DG1
Bosch, X1
Swartz, MJ1
DeMarzo, AM1
Offerhaus, GJ1
Isacoff, WH2
Han, GH1
Yin, ZX1
Meng, XJ1
He, CY1
Zhang, HB1
Sun, AH1
Wu, KC1
Ding, J1
Fan, DM1
Miyazaki, S1
Izukura, M1
Nisijima, J1
Mitchell, J1
Keung, YK1
Löhr, M1
Suga, H1
Okabe, Y1
Ono, N1
Saito, F1
Nagaoka, S1
Tsuruta, O1
Toyonaga, A1
Sata, M1
Clementi, M1
Valenti, M1
Fiorentini, G1
Cantore, M1
Kanavos, E1
Caterino, GP1
Di Giuro, G1
Amicucci, G1
Bendetti, JK1
Barstis, JJ1
Jazieh, AR1
Macdonald, JS2
Philip, PA1
Kolb-van Harten, P1
Rosien, U1
Klöppel, G1
Layer, P1
Hammerstingl, RM1
Böcher, E1
Jacob, U1
Bauer, RW1
Liang, H1
Wang, XN1
Wang, BG1
Pan, Y1
Ding, XW1
Hao, XS1
Edwards, SL1
Brough, R1
Lord, CJ1
Natrajan, R1
Vatcheva, R1
Levine, DA1
Boyd, J1
Reis-Filho, JS1
Ashworth, A1
Chalasani, P1
Kurtin, S1
Dragovich, T1
Steffensrud, S1
Erichsen, H1
Røysland, P1
Halvorsen, TB1
Klepp, R1
Klepp, O1
Wünsch, E1
Petersen, H1
Miura, T3
Haida, K1
Haida, S1
Wada, T2
Bukowski, RM5
Schacter, LP1
Groppe, CW1
Hewlett, JS2
Weick, JK2
Livingston, RB2
Gahbauer, R1
Rodriquez-Antunez, A1
Hermann, R1
Theodors, A1
Goedert, JJ1
Smith, FP2
Tsou, E1
Weiss, RB1
Manabe, T2
Suzuki, T2
Balcerzak, SP1
O'Bryan, RM1
Bonnet, JD1
Chen, TT1
Sternberg, CN1
Magill, GB1
Sordillo, PP1
Cheng, EW1
Bruckner, HW2
Storch, JA1
Brown, JC1
Goldberg, J1
Chamberlin, K1
Shiu, MH1
Cahan, A1
Fogh, J1
Fortner, JG1
Wakui, A1
Taguchi, T5
Tajiri, H2
Kitahara, T1
Yoshimori, M2
Nakamura, K2
Hijikata, A1
Ozaki, H6
Sato, M2
Ishidoya, T1
Joko, Y1
Kiyasu, Y1
Sakai, K1
Kimura, S1
Harvey, JH1
Schein, PS3
Meguro, S1
Nagata, T1
Yokoyama, K1
Chinen, T1
Yamazaki, H1
Kobayashi, T1
Isogai, Y1
Ogawa, M2
Stablein, D1
Korsmeyer, S1
Neefe, J1
Chun, BK1
Woolley, PV1
Agnelli, G1
Gresele, P1
Nenci, GG1
Reich, SD1
Chang, BK1
Gutman, R1
Kinami, Y2
Konishi, K1
Shinmura, K1
Takada, M1
Sakuma, H1
Nagakawa, T2
Miyazaki, I2
Kenmotsu, M1
Endo, T1
Ishii, H1
Ichikawa, J1
Tsunemitsu, K1
Nishiyama, M3
Saeki, S2
Aogi, K2
Hirabayashi, N3
Toge, T3
Weese, JL2
Solin, LJ2
Agarwal, P1
Engstrom, P1
Scher, R2
Paul, AR3
Litwin, S2
Watts, P1
Ilson, DH1
Kelsen, DP1
Palmer, KR1
Kerr, M1
Knowles, G1
Cull, A1
Carter, DC1
Leonard, RC1
Kato, H4
Wakasugi, H1
Yokota, M1
Furukawa, M1
Mukuta, T1
Funakoshi, A1
Coia, L1
Hoffman, J1
Weese, J1
Solin, L1
Weiner, L1
Eisenberg, B1
Paul, A1
Hanks, G1
Gotoh, M2
Monden, M2
Sakon, M2
Kanai, T1
Umeshita, K2
Ikeda, H2
Mori, T1
Furukawa, T1
Kubota, T1
Watanabe, M1
Kitajima, M1
Hoffman, RM1
Satou, T1
Yeung, RS1
Engstrom, PF2
Kowalyshyn, MJ1
Fleming, TR2
Oishi, N1
Taylor, SA1
Baker, LH1
Bakkevold, KE1
Arnesjø, B1
Dahl, O1
Kambestad, B1
Topham, C2
Glees, J2
Coombes, RC2
Lai, DT1
Chu, KM1
Thompson, JF1
Gallagher, JP1
Waugh, R1
Storey, DW1
Stephen, MS1
Kinoshita, T4
Kosuge, T4
Yamamoto, J3
Shimada, K3
Inoue, K1
Koyama, Y1
Mukai, K2
Takada, T2
Matsushiro, T2
Nimura, Y2
Nakayama, T1
Yamauchi, H6
Ogata, Y1
Shimada, H1
Miyakawa, S1
Yamaguchi, A1
Sakoda, K1
Yasuda, H1
Tsukada, K1
Yoshida, K2
Ashida, H1
Ishikawa, Y1
Kotoura, Y1
Kinoshita, H1
Kajiwara, T1
Uchimura, M1
Funabiki, T1
Ikeda, S1
Okada, S2
Muchmore, JH1
Preslan, JE1
George, WJ1
Weckbecker, G1
Raulf, F1
Tolcsvai, L1
Bruns, C1
Osato, H1
Kishimoto, S1
Yamada, T1
Higaki, N1
Taniguchi, K1
Sugimoto, K1
Dohno, K1
Sawabe, Y1
Yamagishi, H1
Yamaguchi, N1
Yamamura, Y1
Oka, T1
Yamaguchi, T2
Yamaoka, N1
Kitamura, K2
Otsuji, E2
Okamoto, K2
Tsuruta, H1
Yata, Y1
Takahashi, T2
Recchia, F1
Sica, G1
Casucci, D1
Rea, S1
Gulino, A1
Frati, L1
Blaszkowsky, L1
Petrowsky, H3
Janshon, G3
Poloczek, Y2
Oremek, G2
Encke, A1
Patiutko, IuI1
Kotel'nikov, AG1
Badalian, KhV1
Sagaĭdak, IV1
Sadoff, L1
Latino, F1
Sunamura, M1
Egawa, S3
Shibuya, K1
Shimamura, H1
Takeda, K1
Kobari, M2
Matsuno, S2
Xue, C1
Minari, Y1
Nio, Y2
Endo, S1
Yano, S1
Itakura, M1
Yamasawa, K1
Tamura, K1
Tokuuye, K1
Fukushima, N2
Kastl, S1
Brunner, T1
Herrmann, O1
Riepl, M1
Grabenbauer, G1
Hohenberger, W1
Klein, P1
Burch, PA1
Ghosh, C1
Schroeder, G1
Allmer, C1
Woodhouse, CL1
Goldberg, RM1
Addo, F1
Bernath, AM1
Tschetter, LK2
Windschitl, HE2
Cobau, CD1
Chakravarthy, A1
Abrams, RA1
Korman, LT1
Zahurek, ML1
Grochow, LB1
O'Reilly, S1
Hurwitz, H1
Lillemoe, KD1
Cameron, JL1
Matumoto, Y1
Tamamori, Y1
Nishino, H1
Yamada, N1
Shimizu, S1
Tanaka, H1
Ohira, M1
Hirakawa, K1
Washizawa, N1
Tokura, N1
Kase, H1
Hattori, T1
Teramoto, T1
Kobayashi, K1
Hirano, K1
Kornek, GV1
Pötter, R1
Selzer, E1
Schratter, A1
Ulrich-Pur, H1
Rogy, M1
Kraus, G1
Scheithauer, W1
Kokhanenko, NIu1
Gershanovich, ML1
Ignashov, AM1
Osipenko, SK1
Rybakov, GV1
Ivanova, NE1
Tanada, M1
Takashima, S2
Endoh, H1
Hyoudou, I1
Jinno, K1
Kataoka, M1
Ni, Q1
Zhang, Q1
Cao, G1
Hofland, J1
Tenbrinck, R1
Erdmann, W1
Homma, H1
Niitsu, Y1
Yachida, S1
Sakamoto, M1
Matsuno, Y1
Hirohashi, S1
Kakizaki, K4
Yokoyama, T1
Shimada, Y1
Sasaki, M1
Kajihara, T1
Hanaue, H1
Shimizu, T1
Arinaga, S2
Karimine, N1
Takamuku, K1
Nanbara, S1
Inoue, H1
Abe, R1
Watanabe, D1
Matsuoka, H1
Ueo, H1
Akiyoshi, T2
Sugiyama, Y1
Saji, S2
Furuta, T2
Azuma, S2
Miya, K1
Umemoto, T1
Takao, H1
Kato, M1
Kanno, A1
Kunimura, T1
Morohoshi, T1
Kikuchi, H1
Kanda, M1
Taguchi, S2
Hatta, Y2
Miura, K1
Mohiuddin, M2
Rosato, F1
Barbot, D2
Schuricht, A1
Biermann, W2
Cantor, R1
Verhees, S1
Flechtner, H1
Queisser, W1
Heim, ME1
Fritz, M1
Trux, F1
Edler, L1
Arredondo, MA1
Chaudhuri, B1
Kar, R1
Crist, KA1
Thomford, NR1
Chaudhuri, PK1
Sato, Y1
Tohma, H1
Shikama, T1
Sakata, Y1
Chiba, Y1
Sato, T1
Kimura, M1
Fukushi, G1
Matsukawa, M1
Wada, K1
Aoyama, H1
Sawada, Y1
Fukushi, M1
Rawson, NS1
Woods, EM1
Fujita, F3
Fujita, M3
Inaba, H2
Sugimoto, T1
Okuyama, Y1
Abad, A1
Rosell, R1
Barnadas, A1
Carles, J1
Ribelles, N1
Solano, V1
Imai, S1
Shiraishi, T1
Tsubono, M1
Morimoto, H1
Tseng, CC1
Tobe, T2
Yamada, H1
Moriai, T3
Takeba, T1
Makino, I1
Jinushi, K1
Kirihara, Y1
Takagami, S1
Ryuji, K1
Yorishima, T1
Noso, Y1
Hisano, H1
Akaishi, S1
Seydel, HG1
Stablein, DM1
Leichman, LP1
Kinzie, JJ1
Thomas, PR1
Bonneterre, J1
Noguchi, A1
Honda, M1
Cullinan, S1
Moertel, CG2
Wieand, HS1
Schutt, AJ1
Krook, JE2
Foley, JF2
Norris, BD1
Kardinal, CG1
Barlow, JF1
Lipton, A1
Harvey, HA1
Santen, RJ1
Stryker, JA1
Barnes, SG1
Walker, BK1
Dixon, RH1
Givant, EM1
Bartholomew, MJ1
Nadjafi, C1
Sassa, T1
Yoshikawa, N1
Hirose, N1
Funatomi, H1
Hasegawa, H1
Hayakawa, N1
Kamiya, J1
Maeda, S1
Shionoya, S1
Kunitomo, K1
Kawahito, M1
Miura, M1
Komi, N1
Vaughn, C1
Chapman, J1
Chinn, B1
Ward, D1
Groshko, G1
Maniscalco, B1
Reznik, S1
Piper, D1
Klapdor, R2
Schwarzenberg, O1
Kühl, JS1
Franke, N2
Bahlo, M2
Takahashi, N1
Kikuti, H1
Asamura, M1
Yasuda, T1
Ishikawa, O1
Ohigashi, H1
Shibata, T1
Sasaki, Y1
Hiratsuka, M1
Kabuto, T1
Furukawa, H1
Imaoka, S1
Iwanaga, T1
Kalman, J1
Spigelman, M1
Gorbaty, MI1
Butwell, N1
Storch, J1
McKenna, A1
Maruyama, T1
Koura, Y1
Kurisu, Y1
Kuroi, K1
Kai, Y1
Cullinan, SA1
Rubin, JR1
Everson, LK1
Twito, DI1
Marschke, RF1
Splinter, TA1
Obertop, H1
Kok, TC1
Oster, MW1
Gray, R1
Panasci, L1
Perry, MC1
Yamauchi, T1
Sakamoto, Y1
Shimozuma, K2
Kimoto, Y1
Takebe, T1
Ohyama, K1
Koba, F1
Tsuji, H1
Takahashi, Y1
Ohta, T1
Mai, M1
Morimoto, M1
Follezou, JY1
Baumelou, A1
Audebert, A1
Beaufils, H1
Karkouche, B1
Kusuyama, T1
Origasa, H1
Uchida, Y1
Yamaoka, K1
Kisu, T1
Mori, H1
Muto, Y1
Cantor, RJ1
Weiss, SM1
Rosato, FE1
Tanemura, H1
Kawata, R1
Suzuki, M1
Shimokawa, K1
Ohashi, H1
Sakata, K1
Hojo, K1
Kishi, K1
Omote, Y1
Stachura, J1
Popiela, T1
Pietroń, M1
Tomaszewska, R1
Kulig, J1
Nowak, K1
Okawa, T1
Kita, M1
Weiner, LM1
Steplewski, Z1
Koprowski, H1
Tanaka, T1
Arizuka, S1
Ashida, Y1
Naitoh, A1
Miyashita, T1
Takahashi, M1
Abe, M1
Hanyu, F1
Nakamura, M1
Suda, Y1
Sekine, T1
Eckhardt, S1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Multi-center Phase I/II Trial of ICM (Irinotecan, Cisplatin, Mitomycin C) With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer[NCT01296763]Phase 118 participants (Actual)Interventional2011-01-31Completed
A Feasibility Study for Individualized Treatment of Patients With Advanced Pancreatic Cancer[NCT00276744]Phase 2249 participants (Actual)Interventional2005-10-31Terminated (stopped due to Because there was no longer an active laboratory component to this study.)
A Pilot Study Using Neoadjuvant Proton Beam Radiation Therapy and Chemotherapy for Marginally Resectable Carcinoma of the Pancreas[NCT00763516]8 participants (Actual)Interventional2009-02-28Completed
A Prospective Randomized Trial of Regional Versus Systemic Continuous Gemcitabine Chemotherapy in the Treatment of Unresectable Pancreatic Cancer[NCT01665625]90 participants (Anticipated)Interventional2012-08-31Not yet recruiting
A Phase II Trial of Infusional 5-Fluorouracil (5-FU), Calcium Leucovorin (LV), Mitomycin-C (Mito-C), and Dipyridamole (D) in Patients With Locally Advanced Unresected Pancreatic Adenocarcinoma[NCT00003018]Phase 254 participants (Actual)Interventional1997-09-30Completed
A Study Using Photon/Proton Beam Radiation Therapy and Chemotherapy for Unresectable Carcinoma of the Pancreas[NCT00685763]13 participants (Actual)Interventional2008-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Who Experienced a Dose Limiting Toxicity to Determine the Maximum Tolerated Dose (MTD)

"1.Phase I - Assess the safety and toxicities of IC with Olaparib escalating to ICM with Olaparib in patients with locally advanced and metastatic pancreatic cancer and determine the phase 2 dose. The number of subjects who experienced a dose limiting toxicity was assessed.Dose-limiting toxicity (DLT) is defined as any of the following study drug-related events experienced during Cycle 1:~Thrombocytopenia with platelets <25,000 x106/l > 7 days. Grade 4 neutropenia lasting ≥7 days. Grade 3 or 4 febrile neutropenia. Grade 3 or greater non-haematological toxicities; excluding grade 3 diarrhoea, nausea or vomiting despite adequate treatment and grade 3 fatigue, lethargy and GGT elevation.~Delay of >2 weeks for next scheduled IC/ICM for reasons of toxicity." (NCT01296763)
Timeframe: 2 years

Interventionparticipants (Number)
Dose Level 10
Dose Level 22
Dose Level 52

Number of Years From Cycle 1, Day 1 On-Study to Date of Death

The overall survival of subjects with locally advanced and/or metastatic pancreatic cancer treated with Irinotecan, Cisplatin, Olaparib, with escalation to the addition of Mitomycin-C. Survival from cycle 1, day 1 on-study to date of death was assessed. (NCT01296763)
Timeframe: 5 years

Interventionyears (survival) from C1D1 to death (Mean)
Dose Level 11.43
Dose Level 20.44
Dose Level 50.60

6-month Overall Survival

Percentage of patients survived at 6 months for patients whose tumors were xenografted and treated in the mouse when treated with the most active agent identified in that model (NCT00276744)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Arm 153

Cumulative Incidence of grade3+ Bowel Perforation, Grade 3+ Bleeding (Ocurring Withing 1 Years) and grade4+ Nonhematologic Acute Adverse Events (Limited to Within 90 Days of Treatment Start)

(NCT00685763)
Timeframe: 1 year following the completion of radiation therapy

Interventionparticipants (Number)
Proton Radiation and Chemotherapy0

Reviews

17 reviews available for mitomycin and Cancer of Pancreas

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
[Radically resected pancreatic cancer and adjuvant treatment. A review of the literature].
    Recenti progressi in medicina, 2013, Volume: 104, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy;

2013
[The update on pancreatic cancer chemotherapy].
    Medicina (Kaunas, Lithuania), 2003, Volume: 39, Issue:10

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic

2003
Pharmacokinetics of the antineoplastic drug mitomycin C in regional chemotherapy using the aortic stop flow technique in advanced pancreatic carcinoma.
    Chemotherapy, 2005, Volume: 51, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Area Under Curve; Biological Availability; Chemotherapy, C

2005
Pseudomyxoma peritonei accompanied by intraductal papillary mucinous neoplasm of the pancreas.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2005, Volume: 5, Issue:4-5

    Topics: Adenocarcinoma, Mucinous; Adenocarcinoma, Papillary; Antineoplastic Combined Chemotherapy Protocols;

2005
[Significance of thermo-chemotherapy for the patients with unresectable pancreas cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Deoxycytidine;

2006
[Arterial infusion chemotherapy for patients with advanced pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Celiac Artery; Deoxycytidine; Drug

2006
Adjuvant postoperative therapy of gastrointestinal malignancies.
    Oncology (Williston Park, N.Y.), 1994, Volume: 8, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined

1994
Treatment of advanced and metastatic pancreatic cancer.
    Frontiers in bioscience : a journal and virtual library, 1998, Nov-01, Volume: 3

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cis

1998
[Ways of improving long-term results of treatment in resectable pancreatic cancer].
    Voprosy onkologii, 1998, Volume: 44, Issue:5

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy; Evaluation

1998
[Therapeutic strategy for the recurrence of pancreatic cancer following pancreatectomy].
    Nihon Geka Gakkai zasshi, 1999, Volume: 100, Issue:2

    Topics: Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin; Neoplasm Recurrence, Local; Pancreatectomy; P

1999
[Radiotherapy and chemotherapy for unresectable pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined

2002
[A new regional arterial infusion chemotherapy for patients with advanced pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Embolization, Therapeutic; Fluorouracil;

2002
[Chemotherapy for advanced pancreatic carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:14

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cyclo

1992
[Recent advanced studies on mitomycins, antitumor activity and mode of action].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:7

    Topics: Animals; Cell Line; Colonic Neoplasms; Humans; Leukemia P388; Mitomycin; Mitomycins; Neoplasms; Panc

1987
The role of chemotherapy in the management of gastric and pancreatic carcinomas.
    Seminars in oncology, 1985, Volume: 12, Issue:4 Suppl 6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy;

1985
Potentiation of antimetabolite action by alkylating agents.
    Advances in enzyme regulation, 1985, Volume: 24

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brea

1985

Trials

57 trials available for mitomycin and Cancer of Pancreas

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Repetitive chemoembolization of hypovascular liver metastases from the most common primary sites.
    Future oncology (London, England), 2013, Volume: 9, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Chemoembolization, Therapeutic; Colorect

2013
Phase II study on combined intravenous and intra-arterial chemotherapy with gemcitabine and mitomycin C in patients with advanced pancreatic cancer.
    Hepato-gastroenterology, 2013, Volume: 60, Issue:126

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Female; Gemcitabine; Humans; In

2013
Effect of multiple-phase regional intra-arterial infusion chemotherapy on patients with resectable pancreatic head adenocarcinoma.
    Chinese medical journal, 2009, Feb-05, Volume: 122, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Gemcitabine

2009
Second-line treatment with a combination of continuous 5-fluorouracil, doxorubicin, and mitomycin-C (conti-FAM) in gemcitabine-pretreated pancreatic and biliary tract cancer.
    American journal of clinical oncology, 2009, Volume: 32, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms

2009
Efficacy and safety of capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated pancreatic, gallbladder, and bile duct carcinoma.
    Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Ne

2010
Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:1

    Topics: Animals; Deoxycytidine; Disease Progression; DNA Breaks, Double-Stranded; Drug Resistance, Neoplasm;

2011
Efficacy of infusional 5-fluorouracil, doxorubicin, and mitomycin-C (iFAM) in the treatment of patients with gemcitabine-pretreated pancreatic cancer and analysis of prognostic factors in a salvage setting.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Chemotherapy, Adjuvant

2011
Salvage therapy with mitomycin and ifosfamide in patients with gemcitabine-resistant metastatic pancreatic cancer: a phase II trial.
    Chemotherapy, 2011, Volume: 57, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease Progression; Dis

2011
B ultrasound-guided hyperthermic intraperitoneal perfusion chemotherapy for the treatment of malignant ascites.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Chemotherapy, Cancer, Regional Perfus

2012
Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jul-15, Volume: 20, Issue:14

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antine

2002
Peripancreatic artery ligation and artery infusion chemotherapy for advanced pancreatic carcinoma.
    Chinese medical journal, 2003, Volume: 116, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arteries; Female; Fluorouracil; Humans; Infusions, I

2003
[Transarterial chemoperfusion of inoperable pancreas carcinoma and local recurrence].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2003, Volume: 175, Issue:5

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Pro

2003
Mitomycin C, carboplatin and protracted venous infusion 5-fluorouracil in advanced oesophago-gastric and pancreatic cancer: results of two phase II studies.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Esophageal Neoplasms; Fema

2003
Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer.
    British journal of cancer, 2004, May-17, Volume: 90, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cholangiocarcinoma; Dox

2004
Gemcitabine and mitomycin C in advanced pancreatic cancer: a single-institution experience.
    Anti-cancer drugs, 2004, Volume: 15, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Deoxycyti

2004
Balloon catheter hypoxic abdominal perfusion with Mitomycin C and Melphalan for locally advanced pancreatic cancer: a phase I-II trial.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2004, Volume: 30, Issue:6

    Topics: Aged; Antineoplastic Agents; Balloon Occlusion; Chemotherapy, Cancer, Regional Perfusion; Female; Hu

2004
Salvage chemotherapy with mitomycin, docetaxel, and irinotecan (MDI regimen) in metastatic pancreatic adenocarcinoma: a phase I and II trial.
    Cancer investigation, 2004, Volume: 22, Issue:5

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytoge

2004
A randomized phase III study of radiotherapy alone or with 5-fluorouracil and mitomycin-C in patients with locally advanced adenocarcinoma of the pancreas: Eastern Cooperative Oncology Group study E8282.
    International journal of radiation oncology, biology, physics, 2005, Aug-01, Volume: 62, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2005
Prospective randomized clinical trial of two drug delivery pathway in the treatment of inoperable advanced pancreatic carcinoma.
    Chinese journal of digestive diseases, 2006, Volume: 7, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C

2006
Hypoxic abdominal stop-flow perfusion in the treatment of advanced pancreatic cancer: a phase II evaluation/trial.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2007, Volume: 33, Issue:1

    Topics: Aged; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Drug Therapy, Comb

2007
Phase II trial of infusional fluorouracil, leucovorin, mitomycin, and dipyridamole in locally advanced unresectable pancreatic adenocarcinoma: SWOG S9700.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, May-01, Volume: 25, Issue:13

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dipy

2007
Treatment with secretin and a cholecystokinin-like peptide in patients with pancreatic cancer. A pilot study.
    Scandinavian journal of gastroenterology, 1984, Volume: 19, Issue:7

    Topics: Adenocarcinoma; Aged; Alanine Transaminase; Alkaline Phosphatase; Amylases; Antineoplastic Combined

1984
Randomized trial of 5-fluorouracil and mitomycin C with or without streptozotocin for advanced pancreatic cancer. A Southwest Oncology Group study.
    Cancer, 1983, Nov-01, Volume: 52, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Therapy,

1983
MIFA III (mitomycin-C, 5-fluorouracil, and adriamycin) chemotherapy for advanced adenocarcinoma of the pancreas.
    American journal of clinical oncology, 1984, Volume: 7, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Doxo

1984
Pharmaceutics: mitomycin C: a brief review.
    Cancer nursing, 1982, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Clinical Trials as Topic; Humans; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stoma

1982
Chemotherapy prolongs survival in inoperable pancreatic carcinoma.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Depression;

1994
Effectiveness of chemotherapy for advanced adenocarcinoma of the pancreas in combined modality therapy.
    Internal medicine (Tokyo, Japan), 1994, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Autonomic Nerve Block; Celiac Plexus; Combined Modal

1994
Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum.
    International journal of radiation oncology, biology, physics, 1994, Aug-30, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

1994
Neoadjuvant chemoradiation in pancreatic and duodenal carcinoma. A Phase II Study.
    Cancer, 1993, Oct-01, Volume: 72, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Chemotherapy, Adjuvant; Combined Modality Therapy; Duodenal Neoplasms;

1993
Evaluation of combination chemotherapy and phase II agents in pancreatic adenocarcinoma. A Southwest Oncology Group study.
    Cancer, 1993, Jan-15, Volume: 71, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorourac

1993
Adjuvant combination chemotherapy (AMF) following radical resection of carcinoma of the pancreas and papilla of Vater--results of a controlled, prospective, randomised multicentre study.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:5

    Topics: Adult; Aged; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvan

1993
Comparison of single-agent epirubicin and 5-fluorouracil/epirubicin/mitomycin in patients with advanced adenocarcinoma of the pancreas.
    Oncology, 1993, Volume: 50 Suppl 1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Epirubicin; Female; Flu

1993
[Prospective randomized trial comparing 1/2 FAM (5-fluorouracil (5-FU) + adriamycin + mitomycin C) versus palliative therapy for the treatment of unresectable pancreatic and biliary tract carcinomas (the 2nd trial in non-resectable patients). Japanese Stu
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Doxorubicin; F

1996
Regional chemotherapy for inoperable pancreatic carcinoma.
    Cancer, 1996, Aug-01, Volume: 78, Issue:3 Suppl

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Infusi

1996
Advanced carcinoma of the pancreas: phase II study of combined chemotherapy, beta-interferon, and retinoids.
    American journal of clinical oncology, 1998, Volume: 21, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Diterpenes; Epirubicin;

1998
Isolated hypoxic perfusion with mitomycin C in patients with advanced pancreatic cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1998, Volume: 24, Issue:6

    Topics: Aged; Antibiotics, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Female; Humans; Hypoxia

1998
Isolated hypoxic perfusion with mitomycin C in patients with advanced pancreatic cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1999, Volume: 25, Issue:3

    Topics: Antibiotics, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Humans; Hypoxia; Mitomycin; N

1999
Neoadjuvant radio-chemotherapy in advanced primarilynon-resectable carcinomas of the pancreas.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2000, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Dose Fractionation, Radiation; Fluor

2000
Phase II evaluation of continuous-infusion 5-fluorouracil, leucovorin, mitomycin-C, and oral dipyridamole in advanced measurable pancreatic cancer: a North Central Cancer Treatment Group Trial.
    American journal of clinical oncology, 2000, Volume: 23, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Female

2000
Combined radiochemotherapy of locally advanced unresectable pancreatic adenocarcinoma with mitomycin C plus 24-hour continuous infusional gemcitabine.
    International journal of radiation oncology, biology, physics, 2001, Mar-01, Volume: 49, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deo

2001
Cardiovascular effects of simultaneous occlusion of the inferior vena cava and aorta in patients treated with hypoxic abdominal perfusion for chemotherapy.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Aged; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Aorta, Thoracic; Chem

2002
[Prospective randomized trial comparing modified FAM (5-fluorouracil (5-FU) + adriamycin + mitomycin C) versus 5-FU alone for the treatment of non-resectable pancreatic and biliary tract carcinomas (the 1st trial in non-resectable patients). Study Group o
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Chemotherapy,

1992
[Treatment of advanced pancreatic cancer with 5-fluorouracil, 4-epidoxorubicin and mitomycin C (FEM II). From the Chemotherapy of Gastrointestinal Tumors Group].
    Onkologie, 1990, Volume: 13, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Epirubicin; F

1990
[Chemotherapy for advanced and recurrent cancer patients--the effect of combination chemotherapy using cisplatin, peplomycin, mitomycin C, adriamycin, and 5-fluorouracil].
    Nihon Gan Chiryo Gakkai shi, 1990, Aug-20, Volume: 25, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Colorectal Neopla

1990
[Comparative study of UFT plus mitomycin C and UFT plus doxorubicin in adenocarcinoma. Hirosaki Cooperative Group of Cancer Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Proto

1992
Randomised trial of epirubicin alone versus 5-fluorouracil, epirubicin and mitomycin C in locally advanced and metastatic carcinoma of the pancreas.
    British journal of cancer, 1991, Volume: 64, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Epirubicin; Fluorouracil; Fol

1991
[Chemotherapy of cancer of the exocrine pancreas].
    Bulletin du cancer, 1990, Volume: 77, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Infusions, Intra-

1990
A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin.
    Cancer, 1990, May-15, Volume: 65, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Proto

1990
FAM chemotherapy +/- aminoglutethimide in the treatment of pancreatic carcinoma.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1990, Volume: 16, Issue:1

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxoru

1990
Activity of 5-fluorouracil, mitomycin C, and methyl CCNU in inoperable adenocarcinoma of pancreas.
    American journal of clinical oncology, 1989, Volume: 12, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alkylating Agents; Antineoplastic Combined Chemother

1989
A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma. Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin.
    JAMA, 1985, Apr-12, Volume: 253, Issue:14

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Costs and

1985
Chemotherapy for advanced pancreatic cancer. A comparison of 5-fluorouracil, adriamycin, and mitomycin (FAM) with 5-fluorouracil, streptozotocin, and mitomycin (FSM).
    Cancer, 1986, Jan-01, Volume: 57, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fl

1986
Phase II studies of drug combinations in advanced pancreatic carcinoma: fluorouracil plus doxorubicin plus mitomycin C and two regimens of streptozotocin plus mitomycin C plus fluorouracil. The Gastrointestinal Tumor Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Admin

1986
Combined modality treatment of localized unresectable adenocarcinoma of the pancreas.
    International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Clinical Trials as To

1988
Treatment of advanced measurable or evaluable pancreatic carcinoma with 17-1A murine monoclonal antibody alone or in combination with 5-fluorouracil, adriamycin and mitomycin (FAM).
    Hybridoma, 1986, Volume: 5 Suppl 1

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials

1986
The role of chemotherapy in the management of gastric and pancreatic carcinomas.
    Seminars in oncology, 1985, Volume: 12, Issue:4 Suppl 6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy;

1985

Other Studies

127 other studies available for mitomycin and Cancer of Pancreas

ArticleYear
Efficacy and safety of preoperative 5-fluorouracil, cisplatin, and mitomycin C in combination with radiotherapy in patients with resectable and borderline resectable pancreatic cancer: a long-term follow-up study.
    World journal of surgical oncology, 2019, Aug-16, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc

2019
Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer.
    Oncotarget, 2017, Jul-04, Volume: 8, Issue:27

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cispla

2017
Inhibition of MAPKAPK2/MK2 facilitates DNA replication upon cancer cell treatment with gemcitabine but not cisplatin.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin; Deoxycytidine; DNA Repl

2018
Molecular analysis of the inhibitory effect of N-acetyl-L-cysteine on the proliferation and invasiveness of pancreatic cancer cells.
    Anti-cancer drugs, 2013, Volume: 24, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cellular Sen

2013
Clinical outcomes in pancreatic adenocarcinoma associated with BRCA-2 mutation.
    Anti-cancer drugs, 2015, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; BRCA2 Protein; Enzyme Inhibitors; Female; Humans; Jews; Male;

2015
The transformation of a nonfunctioning islet cell tumor of the pancreas into a proinsulinoma under conditions of lung metastasis.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:7

    Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Is

2015
WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner.
    Scientific reports, 2016, 09-12, Volume: 6

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle Proteins; Cell Line, Tumo

2016
Prospective study on warfarin and regional chemotherapy in patients with pancreatic carcinoma.
    Journal of gastrointestinal and liver diseases : JGLD, 2008, Volume: 17, Issue:3

    Topics: Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional

2008
Hybrids of aneuploid human cancer cells permit complementation of simple and complex cancer defects.
    Cancer biology & therapy, 2009, Volume: 8, Issue:4

    Topics: Aneuploidy; Cell Line, Tumor; Dose-Response Relationship, Drug; Fanconi Anemia Complementation Group

2009
Experimental study of combination therapy with S-1 against pancreatic cancer.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Prolifer

2009
Mitomycin-induced interstitial pneumonitis in a patient with BRCA2 associated metastatic pancreatic carcinoma.
    JOP : Journal of the pancreas, 2010, May-05, Volume: 11, Issue:3

    Topics: Aged; Antibiotics, Antineoplastic; Genes, BRCA2; Humans; Lung Diseases, Interstitial; Male; Mitomyci

2010
Beneficial effects of 5-Fluorouracil and heparin-based portal infusion chemotherapy combined with mitomycin C and cisplatin after curative resection of pancreatic cancer.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2010, Volume: 10, Issue:2-3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cis

2010
A 67-year-old woman with BRCA 1 mutation associated with pancreatic adenocarcinoma.
    Journal of gastrointestinal cancer, 2011, Volume: 42, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Cisplatin; Deox

2011
Gemcitabine/cisplatin versus 5-fluorouracil/mitomycin C chemoradiotherapy in locally advanced pancreatic cancer: a retrospective analysis of 93 patients.
    Radiation oncology (London, England), 2011, Jul-27, Volume: 6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Female; Fluor

2011
Therapeutic efficacy of a lipid-based prodrug of mitomycin C in pegylated liposomes: studies with human gastro-entero-pancreatic ectopic tumor models.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Jun-10, Volume: 160, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Cholesterol; Colonic Neoplasms; Drug Carriers; Drug Stability;

2012
Irinotecan, cisplatin and mitomycin in inoperable gastro-oesophageal and pancreatic cancers - a new active regimen.
    British journal of cancer, 2002, Oct-07, Volume: 87, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma

2002
[Apoptosis of human pancreatic carcinoma cell lines induced by combinations of chemotherapeutic drugs].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1999, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carboplatin; Doxorubicin; Epirubicin; Flu

1999
Liver metastasis of pancreatic cancer managed by intra-arterial infusion chemotherapy combined with degradable starch microspheres.
    International journal of clinical oncology, 2003, Volume: 8, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Diseases; Carcinoma, Hepatocellular; Chemo

2003
EARLY RESULTS OF COMBINED RADIATION AND CHEMOTHERAPY IN TREATMENT OF MALIGNANT TUMORS.
    Radiology, 1963, Volume: 81

    Topics: Antineoplastic Agents; Colonic Neoplasms; Dactinomycin; Fluorouracil; Humans; Lung Neoplasms; Mitomy

1963
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
    Acta radiologica: therapy, physics, biology, 1964, Volume: 2

    Topics: Biomedical Research; Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Esophageal Neoplasms; Female

1964
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
    Cancer chemotherapy reports, 1964, Volume: 37

    Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exf

1964
Hemodynamic variations during thoracic and abdominal stop-flow regional chemotherapy.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2004, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell L

2004
Functional screen of the fanconi anemia pathway in cancer cells by Fancd2 immunoblot.
    Cancer biology & therapy, 2004, Volume: 3, Issue:6

    Topics: Breast Neoplasms; Drug Resistance, Neoplasm; Fanconi Anemia; Fanconi Anemia Complementation Group D2

2004
Functional defects in the fanconi anemia pathway in pancreatic cancer cells.
    The American journal of pathology, 2004, Volume: 165, Issue:2

    Topics: Cell Cycle Proteins; Cisplatin; Cross-Linking Reagents; DNA Mutational Analysis; DNA-Binding Protein

2004
Neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreas: analysis of histopathology and outcome.
    International journal of gastrointestinal cancer, 2003, Volume: 34, Issue:2-3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Deox

2003
[Adjuvant chemotherapy for unresectable locally advanced pancreatic cancer in light of its characteristics].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Deoxyc

2004
Fluorouracil and mitomycin for pancreatic cancer.
    The Lancet. Oncology, 2005, Volume: 6, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Mit

2005
In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-15, Volume: 11, Issue:20

    Topics: Animals; Antineoplastic Agents; Apoptosis; BRCA2 Protein; Caspases; Cell Cycle; Cell Line, Tumor; Ce

2005
Acute myeloid leukemia following intraperitoneal hyperthermic mitomycin C.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:5

    Topics: Acute Disease; Adenocarcinoma; Adult; Chromosome Inversion; Chromosomes, Human, Pair 16; Female; Hum

2006
Effects of low-dose warfarin and regional chemotherapy on survival in patients with pancreatic carcinoma.
    Scandinavian journal of gastroenterology, 2006, Volume: 41, Issue:9

    Topics: Antibiotics, Antineoplastic; Anticoagulants; Carcinoma; Deoxycytidine; Dose-Response Relationship, D

2006
Pancreatic acinar cell carcinoma with excessive alpha-fetoprotein expression.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2007, Volume: 7, Issue:4

    Topics: Aged; alpha-Fetoproteins; Antineoplastic Agents; Carcinoma, Acinar Cell; Deoxycytidine; Gemcitabine;

2007
[Transarterial chemoperfusion with gemcitabine and mitomycin C in pancreatic carcinoma: results in locally recurrent tumors and advanced tumor stages].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2007, Volume: 179, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Administration Sche

2007
[Management of nonfunctioning islet cell tumors of the pancreas].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:6

    Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcin

2007
Resistance to therapy caused by intragenic deletion in BRCA2.
    Nature, 2008, Feb-28, Volume: 451, Issue:7182

    Topics: Aged; Alleles; Amino Acid Sequence; Base Sequence; BRCA2 Protein; Carboplatin; Cell Line, Tumor; Chr

2008
Response to a third-line mitomycin C (MMC)-based chemotherapy in a patient with metastatic pancreatic adenocarcinoma carrying germline BRCA2 mutation.
    JOP : Journal of the pancreas, 2008, May-08, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Female; Genes, BRCA

2008
Intraarterial infusion chemotherapy in combination with 2450-MHz microwave hyperthermia for cancer of the head of the pancreas.
    Progress in clinical and biological research, 1982, Volume: 107

    Topics: Antibiotics, Antineoplastic; Bleomycin; Drug Therapy, Combination; Female; Hot Temperature; Humans;

1982
Phase II trial of 5-fluorouracil, adriamycin, mitomycin C, and streptozotocin (FAM-S) in pancreatic carcinoma.
    Cancer, 1982, Jul-15, Volume: 50, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Doxorubicin; Drug Evaluation; Drug Therapy, Comb

1982
Mixed beam radiotherapy and combination chemotherapy in localized pancreatic adenocarcinoma-preliminary results.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Elementary Particles;

1982
Intermittent regional infusion of chemotherapy for pancreatic adenocarcinoma. Phase I and II pilot study.
    American journal of clinical oncology, 1982, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Aged; Ampulla of Vater; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineop

1982
Combination chemotherapy pneumonitis: a case report of possible synergistic toxicity.
    Medical and pediatric oncology, 1983, Volume: 11, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Drug Synergism; Drug Therapy, Combination; Female; Huma

1983
[Surgery and drug therapy of advanced pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:9

    Topics: Adult; Aged; Delayed-Action Preparations; Drug Therapy, Combination; Female; Fluorouracil; Humans; M

1982
Phase II trial of combination chemotherapy for pancreatic cancer with 5-fluorouracil, mitomycin C, and hexamethylmelamine.
    Oncology, 1983, Volume: 40, Issue:3

    Topics: Altretamine; Antibiotics, Antineoplastic; Drug Administration Schedule; Drug Evaluation; Drug Therap

1983
Sensitivity of xenografts of human pancreatic adenocarcinoma in nude mice to heat and heat combined with chemotherapy.
    Cancer research, 1983, Volume: 43, Issue:9

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Cisplatin; Fluorouracil; Hot Temperature;

1983
[Analysis of factors affecting clinical cancer chemotherapy].
    Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:10

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Female; Fluorouraci

1983
[An autopsy report of pancreatic carcinoma following the achievement of significant prolongation of survival, despite the lack of a definitive diagnosis].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lymphatic Metastasis

1984
[Constant intra-aortic infusion chemotherapy for advanced abdominal cancer--a technic and the effect in patients with peritoneal metastases].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:7

    Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Coloni

1984
Chemotherapy of pancreatic carcinoma.
    World journal of surgery, 1984, Volume: 8, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; M

1984
Phase I study of 7-N-(p-hydroxyphenyl)-mitomycin C.
    Investigational new drugs, 1984, Volume: 2, Issue:4

    Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Humans; L

1984
Combination chemotherapy for locally advanced pancreatic cancer: equivalence to external beam irradiation and implication for future management.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Huma

1983
Clotting activation after blood transfusion in patients receiving 5-fluorouracil and mitomycin-C treatment.
    Cancer chemotherapy and pharmacology, 1981, Volume: 5, Issue:3

    Topics: Blood Coagulation; Blood Transfusion; Fluorouracil; Humans; Mitomycin; Mitomycins; Pancreatic Neopla

1981
Chemotherapy of pancreatic adenocarcinoma: initial report on two transplantable models in the Syrian hamster.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cricetinae; Cyclophosphamide; Disease Models, Animal

1982
[Effect of cancer chemotherapy for unresectable cancer of the pancreas].
    Nihon Gan Chiryo Gakkai shi, 1982, Oct-20, Volume: 17, Issue:7

    Topics: Antineoplastic Agents; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Mal

1982
[A case of pancreatic cancer surviving for 7 years 11 months following intra-arterial and portal infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:13

    Topics: Adenocarcinoma; Aged; Disease-Free Survival; Female; Humans; Infusions, Intra-Arterial; Infusions, I

1995
[Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:8

    Topics: Carcinoma, Squamous Cell; Cell Division; Dicumarol; DNA Damage; Humans; Leukemia, Myeloid; Mitomycin

1993
A single institutional experience with preoperative chemoradiotherapy for stage I-III pancreatic adenocarcinoma.
    The American surgeon, 1993, Volume: 59, Issue:11

    Topics: Adenocarcinoma; Aged; Angiography; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Surgi

1993
[An appraisal of intraoperative radiotherapy for pancreas cancer].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:3

    Topics: Adult; Aged; Chemotherapy, Adjuvant; Female; Humans; Intraoperative Care; Male; Middle Aged; Mitomyc

1993
A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice.
    Cancer research, 1993, Jul-01, Volume: 53, Issue:13

    Topics: Animals; Disease Models, Animal; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neopl

1993
[Importance of systemic administration of pyrimidine after thermochemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Fluorouracil; Gas

1993
Islet cell carcinoma treated by induction regional chemotherapy and radical total pancreatectomy with liver revascularization and small bowel autotransplantation.
    Surgery, 1996, Volume: 119, Issue:1

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

1996
An aggressive therapeutic approach to carcinoma of the body and tail of the pancreas.
    Cancer, 1996, Jun-01, Volume: 77, Issue:11

    Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Combined Modality Therapy; Duod

1996
Potentiation of the anti-proliferative effects of anti-cancer drugs by octreotide in vitro and in vivo.
    Digestion, 1996, Volume: 57 Suppl 1

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antine

1996
[A patient with pancreatic acinar cell carcinoma, effectively treated by the infusion chemotherapy through hepatic artery using 5-FU, CDDP and MMC].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Acinar Cell; Cisplatin; Drug Administrati

1996
In vitro chemosensitivity of human pancreatic cancer cell lines.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1996, Volume: 20, Issue:3

    Topics: Aged; Antimetabolites; Antineoplastic Agents; Carcinoma, Ductal, Breast; Cisplatin; DNA Replication;

1996
Changes in expression of the antigen recognized by monoclonal antibody A7 in human pancreatic carcinoma cells following exposure to anticancer agents.
    Cancer letters, 1998, Apr-24, Volume: 126, Issue:2

    Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, Neoplasm; Carcinoma; Cell Count; Cell

1998
[Isolated hypoxic perfusion with mitomycin C confers no benefit for patients with advanced pancreatic carcinoma].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115

    Topics: Adenocarcinoma; Aged; Antibiotics, Antineoplastic; Cell Hypoxia; Disease Progression; Female; Humans

1998
Complete clinical remission in a patient with advanced pancreatic cancer using mitomycin C-based chemotherapy: the role of adjunctive heparin.
    American journal of clinical oncology, 1999, Volume: 22, Issue:2

    Topics: Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Drug Therapy,

1999
[The effect of blood-pancreatic juice barrier on antitumor drugs excretion].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1997, Volume: 35, Issue:5

    Topics: Ampulla of Vater; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Dogs; Fluor

1997
[Technique and pathophysiology of isolated hypoxic perfusion of the abdomen].
    Zentralblatt fur Chirurgie, 1999, Volume: 124, Issue:9

    Topics: Acid-Base Equilibrium; Aged; Antibiotics, Antineoplastic; Carbon Dioxide; Catheterization; Chemother

1999
[A case of recurrent pancreatic cancer brought into a complete response by a multimodal treatment with intraarterial chemotherapy and radiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy

2000
Long-term survival after multimodality treatment for resectable pancreatic cancer.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 2000, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Aged; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Mitomycin; Pancr

2000
Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival.
    International journal of radiation oncology, biology, physics, 2000, Nov-01, Volume: 48, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2000
[Intra-arterial infusion chemotherapy in combination with microwave hyperthermia for cancer of head of pancreas and liver metastasis--a case of 16 years survival].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil;

2000
[Hepatic arterial infusion chemotherapy for unresectable liver metastasis of gastrointestinal cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Fluorouracil; Hepati

2000
[A case of stage IV gastric cancer responding to combined chemotherapy by intravenous, intraarterial and intraperitoneal injection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouraci

2000
[Experience with chemotherapy for advanced pancreatic carcinoma].
    Voprosy onkologii, 2000, Volume: 46, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; D

2000
[Multimodal treatment including intraoperative irradiation for advanced pancreatic cancer with extended metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined

2001
["Three steps procedure" in the treatment of large pancreatic head cancer].
    Zhonghua yi xue za zhi, 2000, Volume: 80, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cholecystostomy;

2000
Implications of peritoneal washing cytology in patients with potentially resectable pancreatic cancer.
    The British journal of surgery, 2002, Volume: 89, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2002
[Portal blood levels of mitomycin C after intraperitoneal administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Humans; Infusions, Parenteral; Intraoperative Care; Liver Neoplasms; Mitomycin; Neoplastic Cells, Ci

1992
Correlation of eosinophilia with clinical response in patients with advanced carcinoma treated with low-dose recombinant interleukin-2 and mitomycin C.
    Cancer immunology, immunotherapy : CII, 1992, Volume: 35, Issue:4

    Topics: Aged; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eosinophilia;

1992
[Clinical studies on locoregional immunochemotherapy of peritonitis carcinomatosa].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Cisplatin; Humans; Immunotherapy; Infusions, Parenteral; Mitomycin; Pancreatic Neoplasms; Peritoniti

1992
[Histological evaluation of intra-arterial infusion and systemic chemotherapy of pancreatic carcinomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy

1992
Long-term results of combined modality treatment with I-125 implantation for carcinoma of the pancreas.
    International journal of radiation oncology, biology, physics, 1992, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined

1992
[Portal blood levels of mitomycin C after intraperitoneal administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6

    Topics: Humans; Infusions, Parenteral; Liver Neoplasms; Mitomycin; Pancreatic Neoplasms; Portal Vein

1992
Isolated perfusion of pancreas with mitomycin C.
    American journal of surgery, 1990, Volume: 159, Issue:6

    Topics: Amylases; Animals; Blood Glucose; Chemotherapy, Cancer, Regional Perfusion; Chromatography, High Pre

1990
Evidence of effective multidisciplinary treatment for resectable pancreatic cancer from the viewpoint of the CA19-9 level.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1991,Summer, Volume: 9

    Topics: Aged; Antigens, Tumor-Associated, Carbohydrate; Carcinoma; Combined Modality Therapy; Female; Humans

1991
[Long-term arterial infusion chemotherapy combined with external irradiation therapy for unresectable pancreatic cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Adenocarcinoma; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Combined Modal

1991
[Combination chemotherapy of HO-221, a derivative of benzoylphenylurea with various anticancer agents against human cancer xenografts in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:13

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Div

1991
[Combination of a biscoclaurine alkaloid, cepharanthine, and anticancer agents: effects and mechanism in human gastric and pancreatic carcinoma cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:14

    Topics: Alkaloids; Antineoplastic Agents; Benzylisoquinolines; Cell Division; Doxorubicin; Drug Synergism; F

1991
5-fluorouracil, ifosfamide and mitomycin (FIM) combination for pancreatic-biliary tumors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bili

1991
Chemosensitivity correlation between the primary tumors and simultaneous metastatic lymph nodes of patients evaluated by DNA synthesis inhibition assay.
    Cancer, 1990, Mar-15, Volume: 65, Issue:6

    Topics: Breast Neoplasms; Carbazilquinone; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Doxorubicin; Drug

1990
[Methodological aspects on the histological evaluation of subrenal capsule assay (SRCA)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 2

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyclophosphamide; Cyclosporins; Female; Fluoroura

1990
Experimental study on multidisciplinary treatment of pancreatic cancer.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1990, Volume: 6, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Combined Modality Therapy; Cricetinae; Disease Model

1990
[Clinical studies of in vitro chemosensitivity test evaluated by ATP assay of gastrointestinal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:11

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Scree

1990
Growth-inhibitory effect of combination chemotherapy for human pancreatic cancer cell lines.
    Cancer, 1990, Dec-01, Volume: 66, Issue:11

    Topics: Aclarubicin; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcino

1990
Hyperfractionated radiation and chemotherapy for unresectable localized adenocarcinoma of the pancreas. The Gastrointestinal Tumor Study Group experience.
    Cancer, 1990, Apr-01, Volume: 65, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1990
[Missile therapy of colorectal and pancreatic cancers--clinical trial of monoclonal antibody, A7-NCS, in 73 patients with colorectal and pancreatic cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:6

    Topics: Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Colorectal Neoplasms; Doxorubicin; Drug A

1990
[Hyperthermia: microwave hyperthermia in combination with intra-arterial infusion chemotherapy of cancer of the pancreas].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:6 Suppl

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Hepatocellular; Combined

1985
[Palliative treatment for unresectable cases of pancreatic carcinoma].
    Nihon Geka Gakkai zasshi, 1985, Volume: 86, Issue:12

    Topics: Adult; Aged; Gastroenterostomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Age

1985
[Combination therapy with lentinan, mitomycin c, 5-fluorouracil and radiation--a case of long-term survival of pancreas cancer after palliative surgery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Flu

1987
Effects of MAb BW 494/32 and rTNF-a/rIFN-g alone and in combination in nude mice bearing xenografts of human gastrointestinal/pancreatic carcinomas.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Gastrointestinal Neoplasms; Humans; Interfer

1989
Combined therapy of xenografts of human pancreatic carcinomas with rTNF-alpha and mitomycin C.
    Onkologie, 1989, Volume: 12, Issue:3

    Topics: Animals; Antigens, Tumor-Associated, Carbohydrate; Cell Division; Colorectal Neoplasms; Combined Mod

1989
[Long-term arterial infusion chemotherapy in unresectable pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality T

1989
[Preventive effects of intra-arterial infusion chemotherapy of liver metastasis in non-resectable pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Alprostadil; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Humans; Infusions, Intr

1989
Primary treatment of regional and disseminated pancreatic cancer with hexamethylmelamine, mitomycin C and 5-fluorouracil infusion.
    Oncology, 1989, Volume: 46, Issue:6

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Fluorouracil; Humans; Infusi

1989
[Intra-arterial infusion chemotherapy in non-resectable pancreatic cancer using angiotensin-II and implantable drug delivery system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Adenoma, Bile Duct; Adult; Aged; Aged, 80 and over; Angiotensin II; Antineoplastic Combined Chemothe

1989
Adjuvant chemotherapy after resection of adenocarcinoma of the periampullary region and the head of the pancreas. A non-randomized pilot study.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:2

    Topics: Activities of Daily Living; Adenocarcinoma; Aged; Ampulla of Vater; Antineoplastic Combined Chemothe

1989
[Effects of alternating chemotherapy with 2 non-cross-resistant drug combinations on human alimentary and breast cancer xenografts in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neopla

1987
[Antitumor effect of interferons with chemotherapeutic agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Cell Line; Cells, Cultured; Cisplatin; Drug Therapy, Combination; Fluorouraci

1986
[Effect of intratumor mitomycin-C injection on growth of homologously implanted pancreatic cancer in Syrian golden hamster].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1986, Volume: 83, Issue:8

    Topics: Adenocarcinoma; Animals; Cricetinae; Instillation, Drug; Mesocricetus; Mitomycin; Mitomycins; Neopla

1986
Enhanced chemosensitivity of cells from malignant effusions under condition of exposure to high temperature.
    The Japanese journal of surgery, 1986, Volume: 16, Issue:5

    Topics: Ascitic Fluid; Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; Colony-Forming Units Assay; Dox

1986
[Comparative study with reduction rate of tumor and decrease rate of tumor markers as an effect of MMC on human cancer producing CEA and CA19-9 xenotransplanted in nude mice].
    Nihon Geka Gakkai zasshi, 1987, Volume: 88, Issue:4

    Topics: Animals; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Carcinoembryonic Antigen; Dru

1987
[Anatomo-clinical conference. Hôpital de la Pitié-Salpêtrière. Case n. 2-1987. Anemia, thrombopenia and renal insufficiency in a patient treated for cancer of the pancreas].
    Annales de medecine interne, 1987, Volume: 138, Issue:4

    Topics: Hemolytic-Uremic Syndrome; Humans; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Pancre

1987
[Subrenal capsule assay as a chemosensitivity test (III)--Comparison of host reaction, experimental chemotherapy and use of nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:9

    Topics: Animals; Breast Neoplasms; Cell Line; Drug Evaluation, Preclinical; Fluorouracil; Humans; Mice; Mice

1987
[UFTM therapy in patients with unresectable pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:11

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Injections, In

1987
Cure of advanced gastric cancer by combined chemotherapy with cisplatinum, mitomycin C, and 5-fluorouracil.
    Journal of surgical oncology, 1988, Volume: 38, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorourac

1988
Multidisciplinary treatment for resectable pancreatic cancer.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1988, Volume: 3, Issue:4

    Topics: Aged; Combined Modality Therapy; Humans; Infusions, Intra-Arterial; Intraoperative Care; Middle Aged

1988
[An experimental attempt to potentiate therapeutic effects of combined use of pulsing magnetic fields and antitumor agents].
    Nihon Geka Gakkai zasshi, 1988, Volume: 89, Issue:8

    Topics: Adenocarcinoma; Animals; Cell Division; Combined Modality Therapy; Cricetinae; DNA, Neoplasm; Electr

1988
[Chemotherapy of pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Female

1985
Cytology of solid and papillary epithelial neoplasms of the pancreas: a case report.
    Diagnostic cytopathology, 1988, Volume: 4, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Papillary; Cytodia

1988
[Clinical evaluation of implantable drug delivery system (Port-A-Cath) in cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1988
Chemotherapy for advanced gastric carcinoma.
    JAMA, 1986, Jan-17, Volume: 255, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Mitomycin; Mitomy

1986
[Intra-arterial continuous infusion in patients with advanced and recurrent cancer of the digestive system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Co

1985
[Multidisciplinary treatment of cancer of the pancreas].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:9 Suppl

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Humans; Infusions, Intr

1985
[Present state of the multidisciplinary treatment of pancreatic carcinoma].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:9 Suppl

    Topics: Antibiotics, Antineoplastic; Combined Modality Therapy; Humans; Mitomycin; Mitomycins; Pancreas; Pan

1985
[Biliary and pancreatic excretion of mitomycin C, with special reference to the concomitant use of urokinase].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Bile; Duodenal Neoplasms; Humans; Mitomycin; Mitomycins; Pancreatic Juice; Pancreatic Neoplasms; Uro

1985
[Intratumoral injection therapy of mitomycin C adsorbed to activated carbon particles under ultrasound guidance for pancreatic cancer].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1985, Volume: 82, Issue:12

    Topics: Aged; Charcoal; Female; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Ultr

1985