mitomycin has been researched along with Cancer of Ovary in 141 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twenty-one patients with PC (12 gastric cancer, 5 colorectal cancer, 2 ovarian cancer, 1 pseudomyxoma peritonei, 1 malignant mesothelioma) were treated with CRS + HIPEC with hydroxycamptothecin 20 mg and mitomycin C 30 mg in 12,000 mL of normal saline at 43 +/- ." | 5.14 | Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies: results of 21 cases. ( al-shammaa Hassan, AH; Li, Y; Liu, SY; Lu, YL; Yang, GL; Yang, XJ; Yonemura, Y; Zhang, JW, 2009) |
| " More than 50% of centers administer oxaliplatin (74%), or mitomycin-C (65%) in colorectal cancer; cisplatin in gastric cancer (73%) and mesothelioma (74%)." | 3.88 | Current practice in cytoreductive surgery and HIPEC for metastatic peritoneal disease: Spanish multicentric survey. ( Barrios, P; Cascales-Campos, P; Esteve-Pérez, N; Morales-Soriano, R; Segura-Sampedro, JJ, 2018) |
| " In chromosomal breakage assays, all control cells were mitomycin C (MMC) resistant, but eight samples (five of the six high-risk and three of the eight ovarian cancer) were hypersensitive." | 3.73 | Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer. ( Akkari, Y; Ameziane, N; Bagby, GC; Bale, AE; Cain, JM; Cappuccini, F; Errami, A; Hays, LE; Keeble, W; Liu, HY; Olson, SB; Pejovic, T; Rathbun, RK; Rodgers, WH; Thuillier, P; Torimaru, Y; Yates, JE; Zwaan, CM, 2006) |
| "Twenty-nine women, ages 30-58 years, with advanced ovarian carcinoma were treated with a developmental combination chemotherapy regimen consisting of mitomycin C, etoposide, cisplatin, and carboplatin (MECCA)." | 3.69 | "MECCA": a developmental, dose-intensive, non-cross-resistant platinum-based chemotherapy for advanced ovarian cancer. ( Hoskins, PJ; Lee, N; McMurtrie, EM; Pike, JA; Swenerton, KD, 1996) |
| "The authors report the first results using intraperitoneal hyperthermic chemotherapy with mitomycin C or cisplatinum with protective hypothermia up to 32 degrees C in four cases of peritoneal carcinomatosis secondary to cancer of the ovary which was resistant to conventional treatment." | 3.68 | [Intraperitoneal chemo-hyperthermia in the treatment of peritoneal carcinomatosis of ovarian origin. Initial cases, physiopathologic data]. ( Brachet, A; Braillon, G; Carry, PY; Gilly, FN; Salle, B; Sayag, A, 1993) |
| "35 ovarian cancer patients with ascites have been treated intraperitoneally with mitomycin C or mitoxantrone or interferon beta or tumor necrosis factor (TNF)." | 3.68 | [Locoregional ascites therapy with cytostatic drugs and immune modulators in gynecologic neoplasms]. ( Chronides, A; Diedrich, K; Krebs, D; Mallmann, P; Wagner, U; Werner, A, 1991) |
| "Fourteen cases of adenocarcinoma with pleuritis carcinomatosa (lung cancer 10 cases, ovarian cancer 2 cases, colon cancer 2 cases) were treated with intra-pleural instillation of 7-N-(p-hydroxyphenyl)-mitomycin C (KW-2083), a derivative of mitomycin C." | 3.67 | [Effect of 7-N-(P-hydroxyphenyl)-mitomycin C (KW-2083) against pleuritis carcinomatosa]. ( Eguchi, K; Garcia-Herreros, P; Hoshi, A; Nomori, H; Saijo, N; Sasaki, Y; Shimizu, E; Shinkai, T; Tominaga, K, 1984) |
| "To evaluate the tolerance of peritonectomy procedures (PP) combined with intraperitoneal chemohyperthermia (IPCH) in patients with peritoneal carcinomatosis (PC), a phase II study was carried out from January 1998 to September 2001." | 2.71 | Surgery combined with peritonectomy procedures and intraperitoneal chemohyperthermia in abdominal cancers with peritoneal carcinomatosis: a phase II study. ( Beaujard, AC; Francois, Y; Freyer, G; Gilly, FN; Glehen, O; Guertsch, P; Mithieux, F; Osinsky, D; Panteix, G; Peyrat, P; Vignal, J, 2003) |
| " Pharmacokinetic data from these patients showed very low plasma levels both for KW-2149, as for both known metabolites M-16 and M-18." | 2.68 | Phase I and pharmacokinetic study of KW-2149 given by 24 hours continuous infusion. ( Ardiet, C; Catimel, G; De Bruijn, E; Dirix, L; Tranchand, B; Van Oosterom, A; Verdonk, R, 1995) |
| "Among advanced ovarian cancer, OCCA has worse prognosis compared with serous cystadenocarcinoma because of its poor sensitivity to CDDP-based chemotherapy (CTX)." | 2.68 | [Successful treatment of clear cell adenocarcinoma of the ovary (OCCA) with a combination of CPT-11 and mitomycin C]. ( Hasumi, K; Shimizu, Y; Umezawa, S, 1996) |
| "Among gynecologic cancers, ovarian cancer is treated with chemotherapy as a routine practice." | 2.41 | [Gynecologic cancer-evidenced based chemotherapy]. ( Ochiai, K, 2000) |
| "Occasional advanced cervical cancer patients do not meet the eligibility criteria because of renal dysfunction due to involvement of ureter." | 2.40 | [Consecutive low-dose cisplatin-based chemotherapy for gynecologic malignancies]. ( Shimizu, Y, 1997) |
| "Mitomycin-C (MMC) was used in 20% and oxaliplatin in 10%." | 1.56 | Toxicity profile of chemotherapy agents used in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies. ( Ashwin, KR; Kumar C, R; Rauthan, A; Somashekhar, SP; Yethadka, R; Zaveri, S, 2020) |
| "Pseudomyxoma peritonei is rare, almost always of appendiceal origin, and presents in various ways relevant to abdominal surgeons." | 1.56 | Mode of Presentation in 1070 Patients With Perforated Epithelial Appendiceal Tumors, Predominantly with Pseudomyxoma Peritonei. ( Cecil, TD; Chandrakumaran, K; Dayal, S; Mohamed, F; Moran, BJ; Shariff, US, 2020) |
| "VEGF111b mRNA was detected in ovarian cancer cell lines SKOV3 and OVCAR3 by RT-PCR." | 1.42 | VEGF111b, a C-terminal splice variant of VEGF-A and induced by mitomycin C, inhibits ovarian cancer growth. ( Gu, F; He, D; Kong, J; Li, N; Li, X; Liu, Z; Niu, C; Pan, B; Wang, X; Wang, Y; Yao, Y; Zhang, S; Zheng, L, 2015) |
| "Ovarian cancer was transplanted i." | 1.42 | [Intraperitoneal chemotherapy--a method of improving treatment effectiveness in ovarian cancer]. ( Alexandrov, VA; Belyaev, AM; Belyaeva, OA; Bespalov, VG; Kireeva, GS; Kopteva, OS; Krasilnikova, LA; Maidin, MA; Semenov, AL; Stukov, AN; Vasilieva, IN; Vyshinskaya, EA, 2015) |
| "Mitomycin C (88." | 1.40 | Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: outcomes from a single tertiary institution. ( Hiotis, S; Jibara, G; Labow, DM; Romanoff, A; Sarpel, U; Shrager, B; Tabrizian, P; Yang, MJ, 2014) |
| "and compound 7c exhibit good anticancer activity against ovary (IGR-OV-1), breast (MCF-7) and CNS(SF-295) human cancer cell lines." | 1.36 | Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives. ( Agrawal, SK; Rani, R; Roy, P; Saxena, AK; Singh, J; Sondhi, SM, 2010) |
| "Finally, the growth and metastasis of KGN cells injected subcutaneously (s." | 1.35 | Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line. ( Imai, M; Muraki, M; Saito, H; Seiki, M; Takahashi, Y; Takamatsu, K, 2008) |
| "Hereditary cases of breast and ovarian cancer are often attributed to germ-line mutations of the BRCA1 tumor suppressor gene." | 1.35 | E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. ( Baer, R; Cheng, JT; Jasin, M; Lokshin, M; Ludwig, T; Modi, AP; Reid, LJ; Shakya, R, 2008) |
| "Eligible patients with ovarian cancer in whom pre-operative evaluation indicated that there was a good possibility that disease could be resected to < or = 5 mm underwent surgery followed by intraperitoneal perfusion of cisplatin (100 mg/m2) or mitomycin C (30-40 mg total dose) heated to 41-43 degrees C (105." | 1.34 | Hyperthermic intraperitoneal chemotherapy in conjunction with surgery for the treatment of recurrent ovarian carcinoma. ( Edwards, RP; Gordinier, ME; Helm, CW; Martin, RS; Metzinger, DS; Parker, LP; Randall-Whitis, L, 2007) |
| "A 59-year-old woman with advanced ovarian cancer complained of massive refractory ascites after 2 years' history of chemotherapy." | 1.32 | [A patient with stage IIIc ovarian cancer with massive ascites who was chemotherapy resistant showed complete response with intraperitoneal hyperthermic chemoperfusion]. ( Fujimoto, S; Kobayashi, K; Mutou, T; Ogasawara, T; Ohtsuka, Y; Takahashi, M; Toyosawa, T, 2003) |
| "Expanded gammadeltaTILs from colorectal tumors demonstrated marked cytotoxicities to allogeneic human colon adenocarcinoma HR8348 and lymphoma Daudi cells, as well as xenogeneic murine thymoma EL-4 cell lines." | 1.31 | Antitumor activity of expanded human tumor-infiltrating gammadelta T lymphocytes. ( Ba, D; Chen, J; He, W; Niu, H, 2001) |
| " To explain this tumor selectivity, the distribution of FK317 was investigated after dosing tumor-bearing mice with the 14C-labelled compound." | 1.30 | FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice. ( Fujiwara, T; Inami, M; Kawamura, I; Manda, T; Matsumoto, S; Naoe, Y; Nishigaki, F; Shimomura, K; Takagaki, S; Tsujimoto, S; Yamazaki, S, 1998) |
| " Dose-response curves (DRCs) were calculated by non-linear (sigmoid model: SigmaPlot) and linear curve fitting (median-effect analysis: CalcuSyn)." | 1.30 | Sigmoid model versus median-effect analysis for obtaining dose-response curves for in vitro chemosensitivity testing. ( Petru, E; Pöch, G; Vychodil-Kahr, S, 1999) |
| "Long-term results of epithelial ovarian cancer were not favorable even in mucinous and endometrioid cell types." | 1.29 | Long-term follow-up of patients with epithelial carcinoma of the ovary. ( Arii, Y; Hattori, S; Kawai, M; Kikkawa, F; Ohta, M; Tomoda, Y, 1994) |
| "Fourteen patients with relapsing ovarian cancer were treated with Mitomycin C (Mit C) and 5 Fluorouracil (5-FU)." | 1.28 | Phase II study of mitomycin C and 5 fluorouracil in platinum resistant ovarian cancer. ( Covens, A; Mazurka, J; O'Connell, G; Rusthoven, J, 1992) |
| "This regimen is active in advanced ovarian cancer that has not responded to prior treatment and warrants further study combination with other active drugs as a first-line regimen for ovarian cancer." | 1.28 | Phase II study of combination 4'-epidoxorubicin and mitomycin C in recurrent epithelial ovarian cancer. ( Buxton, J; Chetiyawardana, A; Crawford, M; Lawton, F; Mould, J; O'Brien, M; Patterson, M; Redman, C; Stuart, N; Sykes, V, 1989) |
| "Intracarotid CDDP infusion in combination with angiotensin II was performed in two patients with metastatic brain tumor, lung carcinoma (LC) and ovarian carcinoma (OC)." | 1.27 | [Intracarotid arterial infusion with CDDP in combination with angiotensin II]. ( Hino, N; Mitsuhata, N; Nishigaki, S; Suga, K; Tagusagawa, Y, 1984) |
| "Individual ovarian cancers showed different sensitivities to the drugs." | 1.27 | [A new in vitro chemosensitivity test. Individualized chemotherapy against ovarian cancer and its clinical effect]. ( Ishige, H; Iwasawa, H; Sekiya, S; Takamizawa, H; Tanaka, N; Tokita, H, 1985) |
| "A case of an amylase-producing ovarian cancer in 69-year-old woman has been investigated by light and electron microscopy, as well as by amylase isozyme analysis." | 1.27 | [Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report]. ( Chiba, T; Hiura, M; Kaneko, H; Kawamurra, S; Moriwaki, S; Tanaka, M; Yokoyama, T, 1988) |
| "The effect of mitomycin C on two human ovarian cancer cell lines was measured during several exposure times and concentrations using the Human Tumour Colony-forming Assay (HTCA)." | 1.27 | Variations in exposure to mitomycin C in an in vitro colony-forming assay. ( de Bruijn, EA; Kuppen, PJ; Leeflang, P; Slee, PH; van den Berg, L; van Oosterom, AT, 1986) |
| "A case of brain metastasis in ovarian cancer is reported." | 1.27 | [Metastatic brain tumor after chemotherapy of ovarian cancer]. ( Chen, JT; Fujimoto, I; Fukuda, K; Hasumi, K; Masubuchi, K; Sakamoto, A; Yamauchi, K, 1987) |
| " The clinical course of this case had decided for us which route would be the most effective and would have the least side effect, also, how much of a dosage can be administered as a maximum adoptive dose of an anti-cancer agent, and what kind of a second-line chemotherapy is effective against resistant cancer cells." | 1.27 | [A case report of an advanced ovarian cancer (stage T4) treated with a total amount of 1815 mg of CDDP]. ( Hino, K; Ibaraki, T; Katou, Y; Kiyozuka, Y; Maruyama, M; Nabuchi, K; Ninomiya, Y; Noda, T; Okamura, Y; Oku, M, 1987) |
| " Drug dose-response and time-response curves were plotted, and the IC50 ratio was calculated, for each test compound in order to investigate the mechanism of anticancer action." | 1.27 | [In vitro sensitivity test of a cultured human ovarian cancer cell line to anticancer agents]. ( Fujiya, S; Hatiya, S; Nakabayashi, Y; Tahira, K; Terashima, Y; Yasuda, M; Yoshioka, M, 1985) |
| "Out of 15 evaluable cases, a case of ovarian cancer showed a partial response." | 1.27 | [A clinical trial of a new mitomycin C derivative, KW-2083 (7-N-(p-hydroxyphenyl)-mitomycin C)]. ( Takahashi, H; Takahashi, K; Wakui, A; Yokoyama, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (29.79) | 18.7374 |
| 1990's | 40 (28.37) | 18.2507 |
| 2000's | 29 (20.57) | 29.6817 |
| 2010's | 26 (18.44) | 24.3611 |
| 2020's | 4 (2.84) | 2.80 |
| Authors | Studies |
|---|---|
| Kunz, KR | 1 |
| Iyengar, BS | 1 |
| Dorr, RT | 2 |
| Alberts, DS | 4 |
| Remers, WA | 1 |
| Islam, I | 1 |
| Skibo, EB | 1 |
| Iwasa, K | 1 |
| Moriyasu, M | 1 |
| Yamori, T | 1 |
| Turuo, T | 1 |
| Lee, DU | 1 |
| Wiegrebe, W | 1 |
| Sondhi, SM | 1 |
| Rani, R | 1 |
| Singh, J | 1 |
| Roy, P | 1 |
| Agrawal, SK | 1 |
| Saxena, AK | 1 |
| Mendoza-Sánchez, F | 1 |
| Ángeles-Bueno, WG | 1 |
| Montes-López, GA | 1 |
| Mendoza-Medina, DF | 1 |
| Díaz-Sifuentes, JM | 1 |
| Pérez-Landeros, JE | 1 |
| Somashekhar, SP | 1 |
| Yethadka, R | 1 |
| Kumar C, R | 1 |
| Ashwin, KR | 1 |
| Zaveri, S | 1 |
| Rauthan, A | 1 |
| Codilupi, T | 1 |
| Taube, D | 1 |
| Naegeli, H | 1 |
| Costales, AB | 1 |
| Chambers, L | 1 |
| Chichura, A | 1 |
| Rose, PG | 1 |
| Mahdi, H | 1 |
| Michener, CM | 1 |
| Yao, M | 1 |
| Debernardo, R | 1 |
| Shariff, US | 1 |
| Chandrakumaran, K | 1 |
| Dayal, S | 1 |
| Mohamed, F | 1 |
| Cecil, TD | 1 |
| Moran, BJ | 1 |
| Arjona-Sanchez, A | 1 |
| Aziz, O | 1 |
| Passot, G | 2 |
| Salti, G | 2 |
| Esquivel, J | 1 |
| Van der Speeten, K | 1 |
| Piso, P | 1 |
| Nedelcut, DS | 1 |
| Sommariva, A | 1 |
| Yonemura, Y | 2 |
| Turaga, K | 1 |
| Selvasekar, CR | 1 |
| Rodriguez-Ortiz, L | 1 |
| Sanchez-Hidalgo, JM | 1 |
| Casado-Adam, A | 1 |
| Rufian-Peña, S | 1 |
| Briceño, J | 1 |
| Glehen, O | 3 |
| Gayarre, J | 1 |
| Martín-Gimeno, P | 1 |
| Osorio, A | 1 |
| Paumard, B | 1 |
| Barroso, A | 1 |
| Fernández, V | 1 |
| de la Hoya, M | 1 |
| Rojo, A | 1 |
| Caldés, T | 1 |
| Palacios, J | 1 |
| Urioste, M | 1 |
| Benítez, J | 1 |
| García, MJ | 1 |
| Morales-Soriano, R | 1 |
| Esteve-Pérez, N | 1 |
| Segura-Sampedro, JJ | 1 |
| Cascales-Campos, P | 1 |
| Barrios, P | 1 |
| Gorodnova, TV | 2 |
| Kotiv, KB | 1 |
| Ivantsov, AO | 1 |
| Mikheyeva, ON | 1 |
| Mikhailiuk, GI | 1 |
| Lisyanskaya, AS | 1 |
| Mikaya, NA | 1 |
| Guseynov, KD | 1 |
| Bondarev, NE | 1 |
| Matveyeva, NS | 1 |
| Nekrasova, EA | 1 |
| Sidoruk, AA | 1 |
| Roman, LD | 1 |
| Manikhas, GM | 1 |
| Belyaev, AM | 2 |
| Sokolenko, AP | 2 |
| Berlev, IV | 1 |
| Imyanitov, EN | 2 |
| Burgazli, KM | 1 |
| Mericliler, M | 1 |
| Kavukcu, E | 1 |
| Erdogan, A | 1 |
| Ertan, AK | 1 |
| Takata, K | 1 |
| Reh, S | 1 |
| Tomida, J | 1 |
| Person, MD | 1 |
| Wood, RD | 1 |
| Bakrin, N | 1 |
| Roux, AS | 1 |
| Vaudoyer, D | 1 |
| Gilly, FN | 4 |
| Cotte, E | 1 |
| Tabrizian, P | 1 |
| Shrager, B | 1 |
| Jibara, G | 1 |
| Yang, MJ | 1 |
| Romanoff, A | 1 |
| Hiotis, S | 1 |
| Sarpel, U | 1 |
| Labow, DM | 1 |
| Moiseyenko, VM | 1 |
| Chubenko, VA | 1 |
| Moiseyenko, FV | 1 |
| Zhabina, AS | 1 |
| Komarov, YI | 1 |
| Bogdanov, AA | 1 |
| Bhagwandin, S | 1 |
| Naffouje, S | 1 |
| Delhorme, JB | 1 |
| Triki, E | 1 |
| Romain, B | 1 |
| Meyer, N | 1 |
| Rohr, S | 1 |
| Brigand, C | 1 |
| Li, X | 1 |
| Gu, F | 1 |
| Niu, C | 1 |
| Wang, Y | 1 |
| Liu, Z | 1 |
| Li, N | 1 |
| Pan, B | 1 |
| He, D | 1 |
| Kong, J | 1 |
| Zhang, S | 1 |
| Wang, X | 1 |
| Yao, Y | 1 |
| Zheng, L | 1 |
| Bouhadjari, N | 1 |
| Gabato, W | 1 |
| Calabrese, D | 1 |
| Msika, S | 1 |
| Keita, H | 1 |
| Bespalov, VG | 2 |
| Vyshinskaya, EA | 2 |
| Vasilieva, IN | 1 |
| Maidin, MA | 2 |
| Semenov, AL | 2 |
| Stukov, AN | 2 |
| Kireeva, GS | 1 |
| Belyaeva, OA | 1 |
| Kopteva, OS | 1 |
| Krasilnikova, LA | 1 |
| Alexandrov, VA | 1 |
| Vasil'eva, IN | 1 |
| Barakova, NV | 1 |
| Imai, M | 1 |
| Muraki, M | 1 |
| Takamatsu, K | 1 |
| Saito, H | 1 |
| Seiki, M | 1 |
| Takahashi, Y | 1 |
| Yang, XJ | 1 |
| Li, Y | 1 |
| al-shammaa Hassan, AH | 1 |
| Yang, GL | 1 |
| Liu, SY | 1 |
| Lu, YL | 1 |
| Zhang, JW | 1 |
| Reid, LJ | 1 |
| Shakya, R | 1 |
| Modi, AP | 1 |
| Lokshin, M | 1 |
| Cheng, JT | 1 |
| Jasin, M | 1 |
| Baer, R | 1 |
| Ludwig, T | 1 |
| Kanagavel, D | 1 |
| Pokataev, IA | 1 |
| Fedyanin, MY | 1 |
| Tryakin, AA | 1 |
| Bazin, IS | 1 |
| Narimanov, MN | 1 |
| Yakovleva, ES | 1 |
| Garin, AM | 1 |
| Tjulandin, SA | 1 |
| Hayakawa, T | 1 |
| Zhang, F | 1 |
| Hayakawa, N | 1 |
| Ohtani, Y | 1 |
| Shinmyozu, K | 1 |
| Nakayama, J | 1 |
| Andreassen, PR | 1 |
| Parson, EN | 1 |
| Lentz, S | 1 |
| Russell, G | 1 |
| Shen, P | 1 |
| Levine, EA | 1 |
| Stewart, JH | 1 |
| Vogl, TJ | 1 |
| Naguib, NN | 1 |
| Lehnert, T | 1 |
| Nour-Eldin, NE | 1 |
| Eichler, K | 1 |
| Zangos, S | 1 |
| Gruber-Rouh, T | 1 |
| Kim, KK | 1 |
| Lange, TS | 1 |
| Singh, RK | 1 |
| Brard, L | 1 |
| Moore, RG | 1 |
| Deraco, M | 2 |
| Virzì, S | 1 |
| Iusco, DR | 1 |
| Puccio, F | 1 |
| Macrì, A | 1 |
| Famulari, C | 1 |
| Solazzo, M | 1 |
| Bonomi, S | 1 |
| Grassi, A | 1 |
| Baratti, D | 2 |
| Kusamura, S | 2 |
| Cui, S | 1 |
| Ba, M | 1 |
| Tang, Y | 1 |
| Liu, J | 1 |
| Wu, Y | 1 |
| Wang, B | 1 |
| Zhang, X | 1 |
| Tang, H | 1 |
| Zhong, S | 1 |
| Eveno, C | 1 |
| Goéré, D | 1 |
| Dartigues, P | 1 |
| Honoré, C | 1 |
| Dumont, F | 1 |
| Tzanis, D | 1 |
| Benhaim, L | 1 |
| Malka, D | 1 |
| Elias, D | 1 |
| Li, L | 1 |
| Chen, DB | 1 |
| Lin, C | 1 |
| Cao, K | 1 |
| Wan, Y | 1 |
| Zhao, XY | 1 |
| Nie, CL | 1 |
| Yuan, Z | 1 |
| Wei, YQ | 1 |
| Mithieux, F | 1 |
| Osinsky, D | 1 |
| Beaujard, AC | 1 |
| Freyer, G | 1 |
| Guertsch, P | 1 |
| Francois, Y | 1 |
| Peyrat, P | 1 |
| Panteix, G | 2 |
| Vignal, J | 1 |
| Tanaka, H | 2 |
| Umekawa, T | 1 |
| Nagao, K | 1 |
| Ishihara, A | 2 |
| Toyoda, N | 1 |
| Wang, C | 1 |
| Gu, M | 1 |
| Wang, S | 1 |
| Ma, D | 1 |
| ISHIBASHI, Y | 1 |
| MYHRE, K | 1 |
| FJAERLI, J | 1 |
| OGIER, E | 1 |
| MAIJNELLI, M | 1 |
| PERITI, P | 1 |
| Kobayashi, K | 1 |
| Fujimoto, S | 1 |
| Takahashi, M | 1 |
| Mutou, T | 1 |
| Toyosawa, T | 1 |
| Ohtsuka, Y | 1 |
| Ogasawara, T | 1 |
| Ivanov, S | 2 |
| Zervoudis, S | 1 |
| Huang, X | 1 |
| Cai, SM | 2 |
| Tang, J | 1 |
| Li, ZT | 2 |
| Zang, RY | 2 |
| Aoki, Y | 2 |
| Kurata, H | 1 |
| Watanabe, M | 2 |
| Fujita, K | 2 |
| Tanaka, K | 2 |
| Izzo, L | 1 |
| Pierannunzi, F | 1 |
| Vari, A | 1 |
| Riccardi, S | 1 |
| Tarquini, S | 1 |
| Fermariello, A | 1 |
| Di Giorgio, A | 1 |
| Casullo, A | 1 |
| Caputo, M | 1 |
| Costi, U | 1 |
| Al Radhi, H | 1 |
| Kharrub, Z | 1 |
| Gazzanelli, S | 1 |
| Nishino, K | 1 |
| Amikura, T | 1 |
| Obata, H | 1 |
| Sekine, M | 1 |
| Yahata, T | 1 |
| Raspagliesi, F | 1 |
| Campos Torres, JC | 1 |
| de Souza, GA | 1 |
| Ditto, A | 1 |
| Zanaboni, F | 1 |
| Younan, R | 1 |
| Mariani, L | 1 |
| Laterza, B | 1 |
| Kihira, T | 1 |
| Nomura, Y | 1 |
| Pejovic, T | 1 |
| Yates, JE | 1 |
| Liu, HY | 1 |
| Hays, LE | 1 |
| Akkari, Y | 1 |
| Torimaru, Y | 1 |
| Keeble, W | 1 |
| Rathbun, RK | 1 |
| Rodgers, WH | 1 |
| Bale, AE | 1 |
| Ameziane, N | 1 |
| Zwaan, CM | 1 |
| Errami, A | 1 |
| Thuillier, P | 1 |
| Cappuccini, F | 1 |
| Olson, SB | 1 |
| Cain, JM | 1 |
| Bagby, GC | 1 |
| Helm, CW | 1 |
| Randall-Whitis, L | 1 |
| Martin, RS | 1 |
| Metzinger, DS | 1 |
| Gordinier, ME | 1 |
| Parker, LP | 1 |
| Edwards, RP | 1 |
| Edwards, SL | 1 |
| Brough, R | 1 |
| Lord, CJ | 1 |
| Natrajan, R | 1 |
| Vatcheva, R | 1 |
| Levine, DA | 1 |
| Boyd, J | 1 |
| Reis-Filho, JS | 1 |
| Ashworth, A | 1 |
| Takada, M | 2 |
| Ratanatharathorn, V | 1 |
| Samson, MK | 1 |
| Baker, LH | 1 |
| Pollard, R | 1 |
| Cummings, G | 1 |
| Fraile, RJ | 1 |
| Noda, T | 2 |
| Kosakai, H | 1 |
| Tsujimura, K | 1 |
| Nakanishi, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cytoreductive Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy for the Treatment of Peritoneal Carcinomatosis From Gastrointestinal Cancer: an Open Label, Randomized, Prospective, Phase 2 Clinical Trial[NCT00454519] | Phase 2 | 60 participants (Anticipated) | Interventional | 2007-03-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for mitomycin and Cancer of Ovary
| Article | Year |
|---|---|
Use of synthetic stomata in abdominal carcinomatosis. Case report and literature review.
Topics: Adenocarcinoma, Papillary; Adult; Antineoplastic Combined Chemotherapy Protocols; Argon Plasma Coagu | 2019 |
Discovery of asymptomatic Krukenberg tumors diagnosed during caesarean section: therapy with hyperthermic intraperitoneal chemotherapy.
Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherap | 2013 |
[Consecutive low-dose cisplatin-based chemotherapy for gynecologic malignancies].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; | 1997 |
Individualized chemotherapeutic regimen for each histological subtype of ovarian carcinoma.
Topics: Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; C | 1997 |
[Gynecologic cancer-evidenced based chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Evidence-Based Medicine; Femal | 2000 |
20 trials available for mitomycin and Cancer of Ovary
| Article | Year |
|---|---|
Routine second-look after surgical treatment of colonic peritoneal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemo | 2015 |
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies: results of 21 cases.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma | 2009 |
A prognostic model in patients treated for metastatic gastric cancer with second-line chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring | 2010 |
B ultrasound-guided hyperthermic intraperitoneal perfusion chemotherapy for the treatment of malignant ascites.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Chemotherapy, Cancer, Regional Perfus | 2012 |
Surgery combined with peritonectomy procedures and intraperitoneal chemohyperthermia in abdominal cancers with peritoneal carcinomatosis: a phase II study.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy | 2003 |
Combination chemotherapy with irinotecan hydrochloride (CPT-11) and mitomycin C in platinum-refractory ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Cisplatin; D | 2004 |
Irinotecan hydrochloride (CPT-11) and mitomycin C as the first line chemotherapy for ovarian clear cell adenocarcinoma.
Topics: Adenocarcinoma, Clear Cell; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptotheci | 2005 |
Salvage chemotherapy with a combination of irinotecan hydrochloride and mitomycin C in elderly Japanese patients with gynecological malignancies: a pilot study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Human | 2006 |
[Clinical trial of carmofur (HCFU) in the treatment of malignant ovarian cancer--The first report: combination therapy with endoxan, mitomycin C, and toyomycin].
Topics: Adult; Aged; Antineoplastic Agents; Chromomycin A3; Clinical Trials as Topic; Cyclophosphamide; Drug | 1983 |
Phase II study of mitomycin C plus 5-fluorouracil in patients with refractory ovarian cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Middle Aged; Mit | 1994 |
Lack of activity of 5-fluorouracil plus mitomycin-C as salvage therapy in cisplatin-resistant epithelial ovarian cancer: results of a phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; CA-125 Antigen; Cisp | 1994 |
Phase I and pharmacokinetic study of KW-2149 given by 24 hours continuous infusion.
Topics: Antineoplastic Agents; Carcinoma; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drugs, Inv | 1995 |
[Successful treatment of clear cell adenocarcinoma of the ovary (OCCA) with a combination of CPT-11 and mitomycin C].
Topics: Adenocarcinoma, Clear Cell; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptotheci | 1996 |
[Clinical evaluation of intra-arterial infusion chemotherapy for advanced or recurrent pelvic tumors with or without radiotherapy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplati | 1996 |
[Treatment of postoperative nausea and vomiting with ondansetron in patients administered anti-neoplastic agents].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; | 1996 |
A phase II study of combined CPT-11 and mitomycin-C in platinum refractory clear cell and mucinous ovarian carcinoma.
Topics: Adenocarcinoma, Clear Cell; Adenocarcinoma, Mucinous; Antineoplastic Agents, Phytogenic; Antineoplas | 1998 |
[Clinical usefulness of ondansetron injection in patients receiving cancer chemotherapy].
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cis | 2002 |
Treatment of malignant peritoneal effusion in digestive and ovarian cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplati | 1992 |
Mitomycin C and 5-fluorouracil salvage chemotherapy in platinum-resistant ovarian carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Resistance; Female; Flu | 1992 |
Intermittent intensive combination chemotherapy with cisplatin, doxorubicin, and cyclophosphamide (cyclic PAC chemotherapy) for ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Admin | 1992 |
116 other studies available for mitomycin and Cancer of Ovary
| Article | Year |
|---|---|
Structure-activity relationships for mitomycin C and mitomycin A analogues.
Topics: Animals; Breast Neoplasms; Chemical Phenomena; Chemistry; Colonic Neoplasms; Female; Humans; Leukemi | 1991 |
Structure-activity studies of antitumor agents based on pyrrolo[1,2-a]benzimidazoles: new reductive alkylating DNA cleaving agents.
Topics: Alkylation; Antineoplastic Agents; Aziridines; Benzimidazoles; Colonic Neoplasms; DNA; Female; Free | 1991 |
In vitro cytotoxicity of the protoberberine-type alkaloids.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast | 2001 |
Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; | 2010 |
Toxicity profile of chemotherapy agents used in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neop | 2020 |
CRL4 ubiquitin ligase stimulates Fanconi anemia pathway-induced single-stranded DNA-RPA signaling.
Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Line, Tumor; Cell Su | 2019 |
Effect of platinum sensitivity on the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) in recurrent epithelial ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ovarian Epithelial; Cisplatin; Combined M | 2021 |
Mode of Presentation in 1070 Patients With Perforated Epithelial Appendiceal Tumors, Predominantly with Pseudomyxoma Peritonei.
Topics: Adenocarcinoma, Mucinous; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Appendicitis; Bi | 2020 |
Laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for limited peritoneal metastasis. The PSOGI international collaborative registry.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Colonic Neoplasms; Cy | 2021 |
Characterisation of the novel deleterious RAD51C p.Arg312Trp variant and prioritisation criteria for functional analysis of RAD51C missense changes.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Breast Neoplasms; Carcinoma; Case-Control Studies; Cell | 2017 |
Current practice in cytoreductive surgery and HIPEC for metastatic peritoneal disease: Spanish multicentric survey.
Topics: Antineoplastic Agents; Carcinoma; Cardiac Output; Cisplatin; Colorectal Neoplasms; Cytoreduction Sur | 2018 |
Efficacy of Neoadjuvant Therapy With Cisplatin Plus Mitomycin C in BRCA1-Mutated Ovarian Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Cisplatin; Cytoreduction | 2018 |
Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs.
Topics: Ataxia Telangiectasia Mutated Proteins; Base Sequence; Cell Line; Checkpoint Kinase 1; Cross-Linking | 2013 |
Quality of life after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy: a prospective study of 216 patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Cisplatin; Cohort Stu | 2014 |
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: outcomes from a single tertiary institution.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Blood Transfusio | 2014 |
Evidence for clinical efficacy of mitomycin C in heavily pretreated ovarian cancer patients carrying germ-line BRCA1 mutation.
Topics: Adult; Aged; Alkylating Agents; BRCA1 Protein; Female; Genetic Predisposition to Disease; Germ-Line | 2014 |
Utility of Chemoresponse Assay in Patients Undergoing Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytoreductio | 2015 |
VEGF111b, a C-terminal splice variant of VEGF-A and induced by mitomycin C, inhibits ovarian cancer growth.
Topics: Alternative Splicing; Animals; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Su | 2015 |
Hyperthermic intraperitoneal chemotherapy with cisplatin: Amifostine prevents acute severe renal impairment.
Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy P | 2016 |
[Intraperitoneal chemotherapy--a method of improving treatment effectiveness in ovarian cancer].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophos | 2015 |
Comparative Study of Antitumor Efficiency of Intraperitoneal and Intravenous Cytostatics in Experimental Rats with Disseminated Ovarian Cancer.
Topics: Adenocarcinoma, Papillary; Animals; Antineoplastic Agents; Ascites; Cisplatin; Female; Injections, I | 2017 |
Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line.
Topics: Animals; Biomarkers, Tumor; Cell Growth Processes; Cell Line, Tumor; Disease Progression; Female; Gr | 2008 |
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks.
Topics: Animals; BRCA1 Protein; Breast Neoplasms; Cell Line; Chromosome Aberrations; Cross-Linking Reagents; | 2008 |
MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.
Topics: Breast Neoplasms; Chromatin; Chromosome Breakage; Comet Assay; Cross-Linking Reagents; DNA; DNA Repa | 2010 |
Outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface dissemination from ovarian neoplasms.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Cancer, Regi | 2011 |
Initial experience with repetitive transarterial chemoembolization (TACE) as a third line treatment of ovarian cancer metastasis to the liver: indications, outcomes and role in patient's management.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Cisplatin; Deoxycyti | 2012 |
Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bl | 2012 |
Secondary cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent epithelial ovarian cancer: a multi-institutional study.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ovari | 2012 |
Ovarian metastasis is associated with retroperitoneal lymph node relapses in women treated for colorectal peritoneal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality | 2013 |
hPNAS-4 inhibits proliferation through S phase arrest and apoptosis: underlying action mechanism in ovarian cancer cells.
Topics: Apoptosis; Apoptosis Inducing Factor; Apoptosis Regulatory Proteins; Carbon-Nitrogen Lyases; Caspase | 2013 |
Salvage chemotherapy with a combination of irinotecan hydrochloride and mitomycin C in platinum- and paclitaxel-resistant epithelial ovarian cancer: case reports.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Camptothecin; Carcinoma; Cispl | 2003 |
Comparative study on three chemotherapeutic regimens for the treatment of advanced epithelial ovarian cancer.
Topics: Adult; Aged; Aged, 80 and over; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplat | 2000 |
CANCER CHEMOTHERAPY (MITOMYCIN-C) FOLLOWED BY BONE MARROW TRANSPLANTATION.
Topics: Bone Marrow Transplantation; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Bronchogenic; Choriocarci | 1964 |
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
Topics: Biomedical Research; Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Esophageal Neoplasms; Female | 1964 |
[CHEMOTHERAPY IN TREATMENT OF CARCINOMA OF THE OVARY].
Topics: Antineoplastic Agents; Aziridines; Cyclophosphamide; Drug Therapy; Female; Fluorouracil; Humans; Mit | 1964 |
[A patient with stage IIIc ovarian cancer with massive ascites who was chemotherapy resistant showed complete response with intraperitoneal hyperthermic chemoperfusion].
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Cystadenocarcinoma, Serous | 2003 |
[Metastatic cancer in transposed ovaries after radical Wertheim-Meigs hysterectomy for a stage I B and II A cervical cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Cisplatin; Etoposide; Fema | 2003 |
[Multidisciplinary treatment of recurrent epithelial ovarian carcinoma and prognostic analysis].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Cisplatin; Comb | 2004 |
[Anaesthesiologic problems about hyperthermic intraoperative intraperitoneal chemotherapy].
Topics: Adult; Anesthesia; Antibiotics, Antineoplastic; Antineoplastic Agents; Cisplatin; Female; Hemodynami | 2004 |
Cytoreduction combined with intraperitoneal hyperthermic perfusion chemotherapy in advanced/recurrent ovarian cancer patients: The experience of National Cancer Institute of Milan.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; D | 2006 |
Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer.
Topics: Adult; Aged; Chromosome Breakage; DNA Methylation; DNA, Complementary; Epithelial Cells; Fanconi Ane | 2006 |
Hyperthermic intraperitoneal chemotherapy in conjunction with surgery for the treatment of recurrent ovarian carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Fem | 2007 |
Resistance to therapy caused by intragenic deletion in BRCA2.
Topics: Aged; Alleles; Amino Acid Sequence; Base Sequence; BRCA2 Protein; Carboplatin; Cell Line, Tumor; Chr | 2008 |
[Nonspecific cell-mediated immunity of gynecologic cancer patients and related effects of chemotherapy and immunotherapy].
Topics: Female; Fluorouracil; Humans; Immunity, Cellular; Leukocyte Count; Mitomycin; Mitomycins; Ovarian Ne | 1983 |
Combination chemotherapy with mitomycin C, adriamycin, and cyclophosphamide (MAC) in stage III and IV ovarian cancer.
Topics: Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Middle Aged; Mitomycin; Mi | 1983 |
Effects of radiotherapy and chemotherapy on sister chromatid exchanges in peripheral lymphocytes of the patients with gynecologic cancer.
Topics: Choriocarcinoma; Crossing Over, Genetic; Female; Genital Neoplasms, Female; Humans; Lymphocytes; Mit | 1983 |
[Serum levels of mitomycin C following a high-dose continuous hyperthermic peritoneal perfusion].
Topics: Female; Hot Temperature; Humans; Lung Neoplasms; Mitomycin; Mitomycins; Ovarian Neoplasms; Perfusion | 1984 |
[Intraabdominal administration of MMC adsorbed on activated carbon for management of carcinomatous peritonitis].
Topics: Abdomen; Carbon; Colonic Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Middle Aged; Mitomyc | 1984 |
Scintigraphic peritoneography in advanced ovarian malignancies: its value for chemotherapeutic distribution studies.
Topics: Adult; Aged; Catheterization; Female; Humans; Infusions, Parenteral; Middle Aged; Mitomycin; Mitomyc | 1984 |
[Intracarotid arterial infusion with CDDP in combination with angiotensin II].
Topics: Adenocarcinoma, Papillary; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Bra | 1984 |
[Effect of 7-N-(P-hydroxyphenyl)-mitomycin C (KW-2083) against pleuritis carcinomatosa].
Topics: Adenocarcinoma; Adult; Aged; Anorexia; Antineoplastic Agents; Colonic Neoplasms; Female; Fever; Huma | 1984 |
Sister-chromatid exchanges, chromosomal aberrations and cytotoxicity produced by topoisomerase II-targeted drugs in sensitive (A2780) and resistant (A2780-DX3) human ovarian cancer cells: correlations with the formation of DNA double-strand breaks.
Topics: Antineoplastic Agents; Cell Survival; Chromosome Aberrations; DNA Damage; DNA, Neoplasm; Doxorubicin | 1994 |
[Treatment of advanced and recurrent gynecologic cancer with chemotherapy by cannula perfusion into both internal iliac arteries].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci | 1994 |
Long-term follow-up of patients with epithelial carcinoma of the ovary.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Cyclophosphamide; Cytarabine; | 1994 |
Cytotoxic activity of 7-N-(2-((2-(-gamma-L-glutamylamino)- ethyl)dithio)ethyl)-mitomycin C and metabolites in cell lines with different resistance patterns.
Topics: Animals; Colonic Neoplasms; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Kinet | 1994 |
Mitomycin-C plus a 3-day continuous intravenous infusion of 5-fluorouracil: an inactive salvage regimen for platinum-resistant ovarian carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Resistance | 1993 |
[Intraperitoneal chemo-hyperthermia in the treatment of peritoneal carcinomatosis of ovarian origin. Initial cases, physiopathologic data].
Topics: Aged; Carcinoma; Cisplatin; Combined Modality Therapy; Female; Humans; Hyperthermia, Induced; Inject | 1993 |
Combined antiproliferative activity of 5-fluorouracil and mitomycin-C against primary human ovarian tumors and cell lines in a clonogenic assay.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Administratio | 1993 |
[The results of chemosensitivity test for clear cell adenocarcinoma of the ovary].
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; | 1996 |
Increased DT-diaphorase expression and cross-resistance to mitomycin C in a series of cisplatin-resistant human ovarian cancer cell lines.
Topics: Antineoplastic Agents; Cell Hypoxia; Cisplatin; Drug Resistance, Neoplasm; Female; Glutamate-Cystein | 1996 |
"MECCA": a developmental, dose-intensive, non-cross-resistant platinum-based chemotherapy for advanced ovarian cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Cisplatin; Disease-Fr | 1996 |
Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines.
Topics: Antineoplastic Agents; Cisplatin; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Doxorubi | 1997 |
Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2.
Topics: Antibodies, Monoclonal; Antigens, CD; Apoptosis; Ascitic Fluid; CD28 Antigens; Cells, Cultured; Chro | 1998 |
Combination of cisplatin-procaine complex DPR with anticancer drugs increases cytotoxicity against ovarian cancer cell lines.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 1998 |
FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biotransformation; Body Weight; Carcinoma, Large Cel | 1998 |
Sigmoid model versus median-effect analysis for obtaining dose-response curves for in vitro chemosensitivity testing.
Topics: Antibiotics, Antineoplastic; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Humans; Lin | 1999 |
Growth suppression of human ovarian carcinoma OV-MZ-2a and OV-MZ-32 cells mediated by gene transfer of wild-type p53 enhanced by chemotherapy in vitro.
Topics: Adenocarcinoma; Adenoviridae; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cis | 2000 |
Treatment of peritoneal carcinomatosis with intent to cure.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Colorectal Neoplasms; Combined | 2000 |
Effect of cytoreductive surgery on survival of patients with recurrent epithelial ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; | 2000 |
Camptothecin and mitomycin combination chemotherapy on ovarian clear cell carcinoma with multiple systemic metastases.
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Admin | 2000 |
Metastatic carcinoma in a transposed ovary after radical hysterectomy for a stage 1B cervical adenosquamous cell carcinoma. Case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Cisplatin; Etoposid | 2000 |
Reversal of multidrug resistance and increase in plasma membrane fluidity in CHO cells with R-verapamil and bile salts.
Topics: Animals; Antineoplastic Agents; Cell Division; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Doxorub | 2001 |
Antitumor activity of expanded human tumor-infiltrating gammadelta T lymphocytes.
Topics: Adenocarcinoma; Adult; Aged; Animals; Cytokines; Cytotoxicity Tests, Immunologic; Female; Humans; Im | 2001 |
[Apoptosis as a measure of chemosensitivity to anti-cancer drugs in gynecological cancer].
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cisplatin; Drug Screening Assays, Antitumor | 2002 |
Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary.
Topics: Adenocarcinoma, Clear Cell; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent | 2002 |
Potentiation of topoisomerase I and II inhibitors cell killing by tumor necrosis factor: relationship to DNA strand breakage formation.
Topics: Camptothecin; Cell Death; Cisplatin; DNA Damage; DNA, Neoplasm; Drug Synergism; Epirubicin; Etoposid | 1992 |
[Sensitivity test for anti-tumor agents-3. MTT assay and its clinical effect].
Topics: Antineoplastic Agents; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; F | 1992 |
Phase II study of mitomycin C and 5 fluorouracil in platinum resistant ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Drug Resistance | 1992 |
Doxorubicin and cyclophosphamide, alternated with bleomycin and mitomycin C as a second-line regimen in advanced ovarian carcinoma resistant to cisplatin-based chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 1990 |
[Locoregional ascites therapy with cytostatic drugs and immune modulators in gynecologic neoplasms].
Topics: Ascites; Breast Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Interferon- | 1991 |
[A case of granulosa cell tumor with unusual histologic features].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Combined Modality Therapy; Cy | 1991 |
Mitomycin C cross-resistance induced by adriamycin in human ovarian cancer cells in vitro.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Cystadenocarcinoma; DNA, Neop | 1990 |
Comparative study of combination chemotherapy of ovarian cancer: cyclophosphamide, adriamycin and cisplatin versus 5-fluorouracil, cyclophosphamide and mitomycin C.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; | 1990 |
[Human LAK cell induction and its biological characteristics].
Topics: Antibodies, Monoclonal; Antigens, CD; Cytotoxicity Tests, Immunologic; Esophageal Neoplasms; Female; | 1990 |
[Cumulative survival rate of chemotherapy with CDDP for malignant ovarian tumors].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit | 1990 |
[Intermittent administration of the combination chemotherapy with cis-platin, adriamycin and cyclophosphamide (cyclic-PAC chemotherapy) for the ovarian cancers].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined | 1990 |
[Transformation of ovarian yolk sac tumor to immature teratoma following chemotherapy].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; | 1985 |
[Chemotherapy of ovarian cancer based on in vitro (HTCA) and in vivo (nude mice) chemosensitivity testing].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cisplatin; Colony-Forming Units Assay; Combined Modality | 1985 |
[A new in vitro chemosensitivity test. Individualized chemotherapy against ovarian cancer and its clinical effect].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colony-Forming Units Assay; Cycloph | 1985 |
[A case of amylase-producing ovarian tumor].
Topics: Amylases; Antineoplastic Combined Chemotherapy Protocols; Cystadenocarcinoma; Cytarabine; Female; Fl | 1986 |
[Anti-tumor activity of an anti-human alpha-fetoprotein antibody-human serum albumin-mitomycin C conjugate against human yolk sac tumor maintained in vitro and in nude mice in vivo].
Topics: alpha-Fetoproteins; Animals; Antibodies; Antibody Specificity; Cytotoxicity, Immunologic; Female; Hu | 1986 |
Selective in vitro and in vivo growth inhibition against human yolk sac tumor cell lines by purified antibody against human alpha-fetoprotein conjugated with mitomycin C via human serum albumin.
Topics: Adolescent; alpha-Fetoproteins; Animals; Antibodies; Cell Line; Female; Humans; Mesonephroma; Mice; | 1986 |
[Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report].
Topics: Amylases; Antineoplastic Combined Chemotherapy Protocols; Cystadenocarcinoma; Female; Humans; Middle | 1988 |
[Changes in CA125 concentration in ovarian cancer patients during the remission state--mean attenuating curve and the effectiveness of surgery and chemotherapy].
Topics: Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Combined Chemotherapy Protocols; Biomarkers | 1989 |
Phase II study of combination 4'-epidoxorubicin and mitomycin C in recurrent epithelial ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Epirubicin; Female; Hu | 1989 |
Mitomycin C adsorbed on activated carbon particles: is intraperitoneal chemotherapy effective for synchronous pleuritis carcinomatosa?
Topics: Adult; Female; Humans; Injections, Intraperitoneal; Krukenberg Tumor; Mitomycin; Mitomycins; Ovarian | 1989 |
[An analysis of factors influential in improving the survival rate of patients with ovarian cancer].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclopho | 1989 |
[Reductive effect on ascites, of neocarzinostatin in patients with ovarian cancer].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Ascitic Fluid; Cisplatin; Female; Humans; Infusions, Intra | 1988 |
Enhanced chemosensitivity of cells from malignant effusions under condition of exposure to high temperature.
Topics: Ascitic Fluid; Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; Colony-Forming Units Assay; Dox | 1986 |
Variations in exposure to mitomycin C in an in vitro colony-forming assay.
Topics: Cell Line; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Female; Huma | 1986 |
[Metastatic brain tumor after chemotherapy of ovarian cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cisplatin; Cyclop | 1987 |
[Application of cytopathology in a sensitivity test for anti-tumor agents. I. An experimental study].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Colony-Forming Units Assay; Cytologica | 1987 |
[The effect of thermochemotherapy on ovarian cancer using human ovarian cancer xenograft transplanted to nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Fem | 1986 |
[Side effects and anti-cancer effects following intraperitoneal (ip) administration of mitomycin C (MMC)].
Topics: Female; Humans; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Ovarian Neoplasms; Peritoneum; Ut | 1987 |
[Clinical study of intraperitoneal chemotherapeutic perfusion (IPCP) of mitomycin C (MMC) and intraperitoneal administration of cisplatin].
Topics: Ascites; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Drug Therapy, Combination; Evaluation | 1987 |
Automated analysis of mitomycin C in body fluids by high-performance liquid chromatography with on-line sample pre-treatment.
Topics: Ascitic Fluid; Chromatography, High Pressure Liquid; Dialysis; Female; Humans; Microchemistry; Mitom | 1987 |
[A case report of an advanced ovarian cancer (stage T4) treated with a total amount of 1815 mg of CDDP].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cycloph | 1987 |
[Cisplatin, adriamycin and cyclophosphamide combination chemotherapy of epithelial ovarian cancer].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplati | 1987 |
Enhancement of lymphocytic SCE frequencies in patients with ovarian cancer.
Topics: Adult; Aged; Carcinoma; Cell Division; Female; Humans; In Vitro Techniques; Lymphocytes; Middle Aged | 1988 |
Phase II trial of mitomycin C plus 5-FU in the treatment of drug-refractory ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Fluorouracil; | 1988 |
[Tolerance of intraoperative, intraperitoneal chemotherapy in advanced gynecologic malignancies].
Topics: Adolescent; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Female | 1988 |
[In vitro sensitivity test of a cultured human ovarian cancer cell line to anticancer agents].
Topics: Animals; Antineoplastic Agents; Carbazilquinone; Cell Division; Cell Line; Cell Survival; Cells, Cul | 1985 |
In vitro evaluation of anticancer drugs against ovarian cancer at concentrations achievable by intraperitoneal administration.
Topics: Anthraquinones; Antineoplastic Agents; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubici | 1985 |
Chemotherapy for gynecologic malignancies at Siriraj Hospital, Bangkok.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamid | 1985 |
[A clinical trial of a new mitomycin C derivative, KW-2083 (7-N-(p-hydroxyphenyl)-mitomycin C)].
Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Biliary Tract Neoplasms; Colonic Neoplasms; Colon | 1985 |
[Effects of chemotherapy of advanced malignant ovarian tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Fluorouracil; Human | 1985 |