mitomycin has been researched along with Cancer of Oropharnyx in 21 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Bußmann, L | 1 |
| Laban, S | 1 |
| Wittekindt, C | 1 |
| Stromberger, C | 2 |
| Tribius, S | 1 |
| Möckelmann, N | 1 |
| Böttcher, A | 1 |
| Betz, CS | 1 |
| Klussmann, JP | 1 |
| Budach, V | 3 |
| Muenscher, A | 1 |
| Busch, CJ | 1 |
| Hess, AK | 1 |
| Müer, A | 1 |
| Mairinger, FD | 1 |
| Weichert, W | 1 |
| Stenzinger, A | 1 |
| Hummel, M | 1 |
| Tinhofer, I | 1 |
| Patterson, JM | 1 |
| McColl, E | 1 |
| Carding, PN | 1 |
| Hildreth, AJ | 1 |
| Kelly, C | 1 |
| Wilson, JA | 1 |
| Poettgen, C | 1 |
| Baumann, M | 1 |
| Budach, W | 1 |
| Grabenbauer, G | 1 |
| Marnitz, S | 1 |
| Olze, H | 1 |
| Wernecke, KD | 1 |
| Ghadjar, P | 1 |
| Klug, C | 4 |
| Berzaczy, D | 1 |
| Voracek, M | 3 |
| Nell, C | 1 |
| Ploder, O | 2 |
| Millesi, W | 5 |
| Ewers, R | 4 |
| Perisanidis, C | 1 |
| Sulzbacher, I | 2 |
| Mittlböck, M | 1 |
| Mitchell, D | 1 |
| Czembirek, C | 1 |
| Seemann, R | 1 |
| Schopper, C | 1 |
| Selzer, E | 4 |
| Neuburg, J | 1 |
| Glaser, C | 2 |
| Schwarz, B | 1 |
| Kermer, C | 3 |
| Schmidberger, H | 1 |
| Rave-Fränk, M | 1 |
| Kim, S | 1 |
| Hille, A | 1 |
| Pradier, O | 1 |
| Hess, CF | 1 |
| Wutzl, A | 2 |
| Kornek, G | 1 |
| Poeschl, PW | 1 |
| Oeckher, M | 1 |
| Budihna, M | 2 |
| Soba, E | 2 |
| Smid, L | 2 |
| Zakotnik, B | 2 |
| Strojan, P | 1 |
| Cemazar, M | 1 |
| Fajdiga, I | 1 |
| Zargi, M | 2 |
| Zupevc, A | 1 |
| Lesnicar, H | 2 |
| Koshkareva, Y | 1 |
| Gaughan, JP | 1 |
| Soliman, AM | 1 |
| Berger, C | 2 |
| Chapet, S | 2 |
| Calais, G | 2 |
| Reynaud-Bougnoux, A | 2 |
| Garand, G | 2 |
| le Floch, O | 2 |
| Furlan, L | 1 |
| Fujieda, S | 1 |
| Tanaka, N | 1 |
| Sunaga, H | 1 |
| Noda, I | 1 |
| Sugimoto, C | 1 |
| Tsuzuki, H | 1 |
| Saito, H | 1 |
| Glaser, CM | 1 |
| Kornek, GV | 1 |
| Lang, S | 1 |
| Schüll, B | 1 |
| Watzinger, F | 1 |
| Lavey, RS | 1 |
| Dobrowsky, W | 4 |
| Dobrowsky, E | 3 |
| Strassl, H | 4 |
| Braun, O | 3 |
| Gritzmann, N | 1 |
| Scheiber, V | 2 |
| Schratter-Sehn, AU | 1 |
| Handl-Zeller, L | 1 |
| Braun, OM | 1 |
| Rausch, EM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal Cancer[NCT03691441] | Phase 4 | 280 participants (Anticipated) | Interventional | 2018-01-05 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitomycin and Cancer of Oropharnyx
| Article | Year |
|---|---|
[Concomitant radiochemotherapy with cisplatin (CDDP), 5-fluorouracil (5-FU) and mitomycin C (MMC) in locally advanced carcinoma of the oropharynx. Results of a phase II trial].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 1995 |
6 trials available for mitomycin and Cancer of Oropharnyx
| Article | Year |
|---|---|
Comparative effectiveness trial of transoral head and neck surgery followed by adjuvant radio(chemo)therapy versus primary radiochemotherapy for oropharyngeal cancer (TopROC).
Topics: Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Cause of Death; Chemoradiotherapy, Adjuvant; | 2020 |
MiR-200b and miR-155 as predictive biomarkers for the efficacy of chemoradiation in locally advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemoradiotherapy; C | 2017 |
Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiothe | 2015 |
Inoperable oropharyngeal carcinoma treated with concomitant irradiation, mitomycin C and bleomycin - long term results.
Topics: Adult; Aged; Bleomycin; Carcinoma; Combined Modality Therapy; Disease-Free Survival; Dose-Response R | 2005 |
[Concomitant radiochemotherapy with cisplatin (CDDP), 5-fluorouracil (5-FU) and mitomycin C (MMC) in locally advanced carcinoma of the oropharynx. Results of a phase II trial].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 1995 |
Concomitant radiotherapy with mitomycin C and bleomycin compared with radiotherapy alone in inoperable head and neck cancer: final report.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Co | 1998 |
15 other studies available for mitomycin and Cancer of Oropharnyx
| Article | Year |
|---|---|
Swallowing in the first year after chemoradiotherapy for head and neck cancer: clinician- and patient-reported outcomes.
Topics: Adult; Aged; Antineoplastic Agents; Chemoradiotherapy; Cisplatin; Deglutition; Deglutition Disorders | 2014 |
Preoperative radiochemotherapy in the treatment of advanced oral cancer: outcome of 276 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cohort Studie | 2009 |
Survival of patients with pathologic T0N+ oral and oropharyngeal cancer after neoadjuvant therapy and surgery: the minority report.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C | 2013 |
Quality of life 2-10 years after combined treatment for advanced oral and oropharyngeal cancer.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2002 |
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy | 2003 |
Preoperative radiochemotherapy and radical resection for stages II-IV oral and oropharyngeal cancer: outcome of 222 patients.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2005 |
Preoperative radiochemotherapy and radical resection for stages II to IV oral and oropharyngeal cancer: grade of regression as crucial prognostic factor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Fe | 2005 |
Risk factors for adult laryngotracheal stenosis: a review of 74 cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Dilatation; Female; Humans; Intuba | 2007 |
Enhanced acute toxicity in oropharynx carcinoma treated with radiotherapy and concomitant cisplatin, 5-fluorouracil and mitomycin C.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 1996 |
Expression of hMSH2 correlates with in vitro chemosensitivity to CDDP cytotoxicity in oral and oropharyngeal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; DNA-Bind | 1998 |
Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Erythropoietin; Female; Fl | 2001 |
Combined modality treatment of advanced cancers of the oral cavity and oropharynx.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1991 |
[Incidence of osteoradionecrosis after combined radiotherapy-chemotherapy of head and neck tumors].
Topics: Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; | 1991 |
Response to preoperative concomitant radiochemotherapy with mitomycin C and 5-fluorouracil in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1989 |
[Preoperative radiochemotherapy in advanced oral and oropharyngeal carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1987 |