mitomycin has been researched along with Cancer of Mouth in 26 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty one patients with resectable oral cancer received two courses of induction chemotherapy with peplomycin (PEP), vincristine (VCR), mitomycin C (MMC) and cisplatin (CDDP)." | 2.68 | [Clinical and histological effect of induction chemotherapy with peplomycin, vincristine, mitomycin C and cis-platinum on oral squamous cell carcinomas]. ( Hayashido, Y; Hiranuma, T; Matsuya, T; Mima, T; Ogura, T; Sakai, T; Shirasuna, K; Usui, M, 1995) |
| "Ninety-seven patients with oral squamous cell carcinoma, treated preoperatively with radiotherapy in combination with chemotherapy or cetuximab, were included in this retrospective analysis." | 1.48 | P16 positivity and regression grade predict survival after neoadjuvant radiotherapy of OSCC. ( Eder-Czembirek, C; Fuereder, T; Selzer, E; Sulzbacher, I, 2018) |
| "Oral squamous cell carcinoma (OSCC) may develop in young adults." | 1.43 | Sensitivity to chromosomal breakage as risk factor in young adults with oral squamous cell carcinoma. ( Braakhuis, BJ; Brakenhoff, RH; Flach, GB; Graveland, AP; Joenje, H; Leemans, CR; Nieuwint, AW; Oostra, AB, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (15.38) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Patra, S | 1 |
| Singh, A | 1 |
| Praharaj, PP | 1 |
| Mohanta, NK | 1 |
| Jena, M | 1 |
| Patro, BS | 1 |
| Abusharha, A | 1 |
| Patil, S | 1 |
| Bhutia, SK | 1 |
| Eder-Czembirek, C | 1 |
| Sulzbacher, I | 3 |
| Fuereder, T | 1 |
| Selzer, E | 5 |
| Budach, V | 2 |
| Stromberger, C | 1 |
| Poettgen, C | 1 |
| Baumann, M | 1 |
| Budach, W | 2 |
| Grabenbauer, G | 1 |
| Marnitz, S | 1 |
| Olze, H | 1 |
| Wernecke, KD | 1 |
| Ghadjar, P | 1 |
| Braakhuis, BJ | 1 |
| Nieuwint, AW | 1 |
| Oostra, AB | 1 |
| Joenje, H | 1 |
| Flach, GB | 1 |
| Graveland, AP | 1 |
| Brakenhoff, RH | 1 |
| Leemans, CR | 1 |
| Klug, C | 4 |
| Berzaczy, D | 1 |
| Voracek, M | 3 |
| Nell, C | 1 |
| Ploder, O | 2 |
| Millesi, W | 5 |
| Ewers, R | 4 |
| Perisanidis, C | 1 |
| Mittlböck, M | 1 |
| Mitchell, D | 1 |
| Czembirek, C | 1 |
| Seemann, R | 1 |
| Schopper, C | 1 |
| Brown, TA | 1 |
| Ridge, JA | 1 |
| Goldberg, M | 1 |
| Neuburg, J | 1 |
| Glaser, C | 2 |
| Schwarz, B | 1 |
| Kermer, C | 3 |
| Schmidberger, H | 1 |
| Rave-Fränk, M | 1 |
| Kim, S | 1 |
| Hille, A | 1 |
| Pradier, O | 1 |
| Hess, CF | 1 |
| Wutzl, A | 2 |
| Kornek, G | 1 |
| Poeschl, PW | 1 |
| Oeckher, M | 1 |
| Shintani, S | 1 |
| Hino, S | 1 |
| Nakashiro, K | 1 |
| Hamakawa, H | 1 |
| Kohno, N | 1 |
| Ichikawa, G | 1 |
| Nakazawa, E | 1 |
| Kusunoki, M | 1 |
| Nishiya, M | 1 |
| Nishiyama, M | 1 |
| Saeki, S | 1 |
| Aogi, K | 1 |
| Hirabayashi, N | 1 |
| Toge, T | 1 |
| Stuschke, M | 1 |
| Dinges, S | 1 |
| Jahnke, K | 1 |
| Heselmann, I | 1 |
| Unger, A | 1 |
| Stüben, G | 1 |
| Sack, H | 1 |
| Shirasuna, K | 1 |
| Ogura, T | 2 |
| Mima, T | 1 |
| Hiranuma, T | 2 |
| Sakai, T | 1 |
| Hayashido, Y | 2 |
| Matsuya, T | 2 |
| Usui, M | 1 |
| Okura, M | 1 |
| Adachi, T | 1 |
| Aikawa, T | 1 |
| Yoshioka, H | 1 |
| Kogo, M | 1 |
| Fujieda, S | 1 |
| Tanaka, N | 1 |
| Sunaga, H | 1 |
| Noda, I | 1 |
| Sugimoto, C | 1 |
| Tsuzuki, H | 1 |
| Saito, H | 1 |
| Muraki, Y | 1 |
| Tateishi, A | 1 |
| Seta, C | 1 |
| Fukuda, J | 1 |
| Haneji, T | 2 |
| Oya, R | 1 |
| Ikemura, K | 1 |
| Kobayashi, N | 1 |
| Okamura, H | 1 |
| Morimoto, H | 1 |
| Glaser, CM | 1 |
| Kornek, GV | 1 |
| Lang, S | 1 |
| Schüll, B | 1 |
| Watzinger, F | 1 |
| Lavey, RS | 1 |
| Dobrowsky, W | 4 |
| Dobrowsky, E | 3 |
| Strassl, H | 4 |
| Braun, O | 3 |
| Gritzmann, N | 2 |
| Scheiber, V | 2 |
| Fukazawa, H | 1 |
| Sekiyama, S | 1 |
| Yuki, K | 1 |
| Matsumoto, D | 1 |
| Takase, K | 1 |
| Segawa, A | 1 |
| Takamaru, H | 1 |
| Braun, OM | 1 |
| Neumeister, B | 1 |
| Neuhold, N | 1 |
| Siebenhandl, A | 1 |
| Wimmer, M | 1 |
| Holzner, JH | 1 |
| Popp, W | 1 |
| Rausch, EM | 1 |
4 trials available for mitomycin and Cancer of Mouth
| Article | Year |
|---|---|
Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiothe | 2015 |
[Clinical trial of chemotherapy identified according to chemosensitivity assay for oral cancer patients with unresectable recurrent lesions].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedu | 2006 |
[Clinical and histological effect of induction chemotherapy with peplomycin, vincristine, mitomycin C and cis-platinum on oral squamous cell carcinomas].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dr | 1995 |
Induction chemotherapy is associated with an increase in the incidence of locoregional recurrence in patients with carcinoma of the oral cavity: results from a single institution.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Pr | 1998 |
22 other studies available for mitomycin and Cancer of Mouth
| Article | Year |
|---|---|
SIRT1 inhibits mitochondrial hyperfusion associated mito-bulb formation to sensitize oral cancer cells for apoptosis in a mtROS-dependent signalling pathway.
Topics: Apoptosis; Cisplatin; Humans; Mitochondrial Dynamics; Mitomycin; Mouth Neoplasms; Sirtuin 1; Superox | 2023 |
P16 positivity and regression grade predict survival after neoadjuvant radiotherapy of OSCC.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradiothera | 2018 |
Sensitivity to chromosomal breakage as risk factor in young adults with oral squamous cell carcinoma.
Topics: Adult; Carcinoma, Squamous Cell; Chromosome Breakage; DNA Damage; Fanconi Anemia; Female; Genetic Pr | 2016 |
Preoperative radiochemotherapy in the treatment of advanced oral cancer: outcome of 276 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cohort Studie | 2009 |
Survival of patients with pathologic T0N+ oral and oropharyngeal cancer after neoadjuvant therapy and surgery: the minority report.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C | 2013 |
Gastrostomy-site tumor recurrence is not always fatal.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brachytherapy; Carcinoma, Squamous Cell; Flu | 2003 |
Quality of life 2-10 years after combined treatment for advanced oral and oropharyngeal cancer.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2002 |
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy | 2003 |
Preoperative radiochemotherapy and radical resection for stages II-IV oral and oropharyngeal cancer: outcome of 222 patients.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2005 |
Preoperative radiochemotherapy and radical resection for stages II to IV oral and oropharyngeal cancer: grade of regression as crucial prognostic factor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Fe | 2005 |
Induction chemotherapy with cisplatin, etoposide, and mitomycin-C (PEM) regimen in advanced cases with cancer of pharynx and oral cavity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, | 1995 |
[Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
Topics: Carcinoma, Squamous Cell; Cell Division; Dicumarol; DNA Damage; Humans; Leukemia, Myeloid; Mitomycin | 1993 |
[Accelerated hyperfractionated radiotherapy combined with simultaneous chemotherapy in locally advanced pharyngeal and oral carcinomas].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 1994 |
Expression of hMSH2 correlates with in vitro chemosensitivity to CDDP cytotoxicity in oral and oropharyngeal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; DNA-Bind | 1998 |
Fas antigen expression and outcome of oral squamous cell carcinoma.
Topics: Actuarial Analysis; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2000 |
Peplomycin-induced apoptosis in oral squamous carcinoma cells depends on bleomycin sensitivity.
Topics: Antibiotics, Antineoplastic; Apoptosis; Bleomycin; Carcinoma, Squamous Cell; Colorimetry; DNA Fragme | 2001 |
Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Erythropoietin; Female; Fl | 2001 |
Combined modality treatment of advanced cancers of the oral cavity and oropharynx.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1991 |
[Clinical studies of B-M therapy in oral cancer with multidisciplinary treatment].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Co | 1986 |
Response to preoperative concomitant radiochemotherapy with mitomycin C and 5-fluorouracil in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1989 |
Histological grading of therapy induced regression in squamous cell carcinomas of the oral cavity. A morphological and immunohistochemical study.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; H | 1989 |
[Preoperative radiochemotherapy in advanced oral and oropharyngeal carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1987 |