mitomycin has been researched along with Cancer of Gastrointestinal Tract in 72 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult patients with advanced leiomyosarcomas received intravenous chemotherapy as outpatients with dacarbazine 750 micrograms/m2, mitomycin 6 mg/m2, doxorubicin 40 mg/m2, and cisplatin 60 mg/m2 on day 0, with granulocyte macrophage colony stimulating factor (GM-CSF, sagramostim) 250 mcg/m2 given s." | 9.10 | Contrast of response to dacarbazine, mitomycin, doxorubicin, and cisplatin (DMAP) plus GM-CSF between patients with advanced malignant gastrointestinal stromal tumors and patients with other advanced leiomyosarcomas. ( Buckner, JC; Edmonson, JH; Mahoney, MR; Marks, RS, 2002) |
| "A prospective Phase II trial was carried out with 83 patients who had digestive tract cancer and peritoneal carcinomatosis to evaluate the tolerance and efficacy of IPCH with mitomycin C (MMC) associated with surgery." | 9.09 | Intraperitoneal chemohyperthermia with mitomycin C for digestive tract cancer patients with peritoneal carcinomatosis. ( Beaujard, AC; Bienvenu, J; Caillot, JL; Francois, Y; Garbit, F; Gilly, FN; Glehen, O; Grandclément, E; Panteix, G; Vignal, J, 2000) |
| "For prevention of the chemotherapy-induced stomatitis we administered allopurinol mouthwash to 15 out of 38 patients who underwent PMUE regimen." | 7.68 | [Prophylactic effect of allopurinol mouthwash against stomatitis induced by the chemotherapy (PMUE regimen) for gastrointestinal malignancies]. ( Anada, E; Fujimura, T; Fujita, H; Haryo, S; Sawasaki, K; Shima, Y; Shiota, S, 1991) |
| "A regimen combining hepatic irradiation and intravenous dacarbazine and mitomycin C for treating colorectal adenocarcinoma with liver metastases offers no advance in the management of patients with this disease." | 7.67 | Inefficacy of dacarbazine, mitomycin C, and hepatic irradiation in patients with metastatic adenocarcinoma of the gastrointestinal tract. ( Evans, M; Hellmann, K; Jones, R; Newton, K; Peters, N; Phillips, RH; Smith, BJ, 1984) |
| "Mitomycin C was administered as a perfusate at 10 mg/l." | 5.32 | Treatment of peritoneal carcinomatosis in patients with digestive cancers with combination of intraperitoneal hyperthermia and mitomycin C. ( Banssillon, V; Bienvenu, J; Francois, Y; Garbit, F; Gilly, FN; Glehen, O; Grandclément, E; Panteix, G; Sadeghi-Looyeh, B; Sayag-Beaujard, AC; Vignal, J, 2004) |
| "Adult patients with advanced leiomyosarcomas received intravenous chemotherapy as outpatients with dacarbazine 750 micrograms/m2, mitomycin 6 mg/m2, doxorubicin 40 mg/m2, and cisplatin 60 mg/m2 on day 0, with granulocyte macrophage colony stimulating factor (GM-CSF, sagramostim) 250 mcg/m2 given s." | 5.10 | Contrast of response to dacarbazine, mitomycin, doxorubicin, and cisplatin (DMAP) plus GM-CSF between patients with advanced malignant gastrointestinal stromal tumors and patients with other advanced leiomyosarcomas. ( Buckner, JC; Edmonson, JH; Mahoney, MR; Marks, RS, 2002) |
| "A prospective Phase II trial was carried out with 83 patients who had digestive tract cancer and peritoneal carcinomatosis to evaluate the tolerance and efficacy of IPCH with mitomycin C (MMC) associated with surgery." | 5.09 | Intraperitoneal chemohyperthermia with mitomycin C for digestive tract cancer patients with peritoneal carcinomatosis. ( Beaujard, AC; Bienvenu, J; Caillot, JL; Francois, Y; Garbit, F; Gilly, FN; Glehen, O; Grandclément, E; Panteix, G; Vignal, J, 2000) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "For prevention of the chemotherapy-induced stomatitis we administered allopurinol mouthwash to 15 out of 38 patients who underwent PMUE regimen." | 3.68 | [Prophylactic effect of allopurinol mouthwash against stomatitis induced by the chemotherapy (PMUE regimen) for gastrointestinal malignancies]. ( Anada, E; Fujimura, T; Fujita, H; Haryo, S; Sawasaki, K; Shima, Y; Shiota, S, 1991) |
| "A regimen combining hepatic irradiation and intravenous dacarbazine and mitomycin C for treating colorectal adenocarcinoma with liver metastases offers no advance in the management of patients with this disease." | 3.67 | Inefficacy of dacarbazine, mitomycin C, and hepatic irradiation in patients with metastatic adenocarcinoma of the gastrointestinal tract. ( Evans, M; Hellmann, K; Jones, R; Newton, K; Peters, N; Phillips, RH; Smith, BJ, 1984) |
| "Fourteen patients with adenocarcinoma of the gastrointestinal tract and pancreas treated with mitomycin C(MMC) and 5-fluorouracil (5-FU) had renal impairment 6-11 months from the beginning of MMC therapy." | 3.66 | Renal disease after mitomycin C therapy. ( Hanna, WT; Krauss, S; Murphy, WM; Regester, RF, 1981) |
| "Three women with adenocarcinoma of cardia, adenocarcinoma of liver or ileum carcinoid tumor, respectively, were treated with mitomycin C (MMC) and 5-fluoro-uracil (5-FU)." | 3.66 | [Mytomycin C nephrotoxicity. 3 new cases and review of the literature]. ( Ang, KS; Cledes, J; Hervé, JP; Leguy, P; Leroy, JP; Ramée, MP; Simon, P; Vignoud, J, 1982) |
| "To evaluate the tolerance of peritonectomy procedures (PP) combined with intraperitoneal chemohyperthermia (IPCH) in patients with peritoneal carcinomatosis (PC), a phase II study was carried out from January 1998 to September 2001." | 2.71 | Surgery combined with peritonectomy procedures and intraperitoneal chemohyperthermia in abdominal cancers with peritoneal carcinomatosis: a phase II study. ( Beaujard, AC; Francois, Y; Freyer, G; Gilly, FN; Glehen, O; Guertsch, P; Mithieux, F; Osinsky, D; Panteix, G; Peyrat, P; Vignal, J, 2003) |
| "The aim of this study was to define the maximum tolerated dose (MTD) of bolus mitomycin C (MMC) in combination with 24 h-continuous infusion of 5-flourouracil (FU) plus folinic acid, and to assess the toxicity and activity in patients with previously treated colorectal and gastric cancer." | 2.71 | Protracted infusional 5-fluorouracil plus high-dose folinic acid combined with bolus mitomycin C in patients with gastrointestinal cancer: a phase I/II dose escalation study. ( Bokemeyer, C; Hartmann, JT; Hofheinz, RD; Honecker, F; Käfer, G; Kanz, L; Köhne, CH; Nehls, O; Oechsle, K; Quietzsch, D; Wein, A, 2003) |
| " Four cohorts of patients were recruited with MMC given at 8 mg/m2 for the first 3 levels together with irinotecan at 300 mg/m2, 325 mg/m2, and 350 mg/m2; the fourth dose level was given with MMC at 10 mg/m2 and irinotecan at 325 mg/m2." | 2.70 | Phase I-II study of irinotecan in combination with mitomycin C in patients with advanced gastrointestinal cancer. ( Adam, R; Antoine, EC; Bassot, V; Benhammonda, A; Bismuth, H; Castaing, D; Gil-Delgado, MA; Grapin, JP; Guinet, F; Khayat, D, 2001) |
| "In the present study, repeated hepatic dearterialization combined with intra-arterial infusion chemotherapy was performed in patients with unresectable tumors of the liver." | 2.68 | [Efficacy of repeated hepatic dearterialization combined with intra-arterial infusion chemotherapy for unresectable tumors of the liver]. ( Hashimoto, N; Hayashi, T; Kohno, H; Kubota, H; Nagasue, N; Ono, T; Uchida, M; Yamanoi, A, 1995) |
| "Bibasilar atelectasis and pleural effusions are common findings after IPHC with MMC, but most of them do not necessarily warrant intervention." | 2.68 | Thoracic complications in patients undergoing intraperitoneal heated chemotherapy with mitomycin following cytoreductive surgery. ( Chen, MY; Chiles, C; Choplin, RH; Fleming, RA; Loggie, BW; Perini, MA, 1997) |
| " The half-life in the peritoneal fluid (t1/2p) and the rate constant from the peritoneal fluid to the systemic circulation (ka) were nearly equal for both 5-fluorouracil and mitomycin C (t1/2p, 1." | 2.67 | Pharmacokinetic characteristics of 5-fluorouracil and mitomycin C in intraperitoneal chemotherapy. ( Hasegawa, M; Hasegawa, T; Ito, A; Kuzuya, T; Nabeshima, T; Yamauchi, M, 1994) |
| " QDBS syndrome is somehow related to immuno-deficiency and blood hypercoagulability, the method of Yiqi Huoxue (YQHX) which used to be combined with chemotherapy could not only reduce the toxic-side effects of chemotherapy, but also improve the cellular immune function and hemorheology." | 2.67 | [Studies of guben quyu No I combined with chemotherapy in treating cancer]. ( Peng, XM; Rao, XQ; Yu, RC, 1994) |
| "Mitomycin C was given at a fixed dose of 20 mg/m2 at the end of the BW12C infusion." | 2.67 | Pharmacokinetics of BW12C and mitomycin C, given in combination in a phase 1 study in patients with advanced gastrointestinal cancer. ( Bleehen, NM; Dennis, IF; Ramsay, JR; Workman, P, 1993) |
| "Fifty of 80 cases had advanced gastric cancer, 30 had pancreatic cancer or other cancers, such as colon cancer, and biliary tract cancer." | 2.66 | [Controlled study of MQF-OK therapy with FT and with UFT on various advanced gastrointestinal cancers. Hirosaki Cooperative Study Group of Cancer Chemotherapy]. ( Baba, T; Furukohori, N; Itoh, T; Kawata, K; Kimura, T; Munakata, A; Saitoh, S; Sakata, Y; Suzuki, H; Tamura, Y, 1988) |
| "Peritoneal carcinomatosis is a common manifestation of digestive-tract cancer and has been regarded a terminal disease with a short median survival." | 2.42 | Peritoneal carcinomatosis from digestive tract cancer: new management by cytoreductive surgery and intraperitoneal chemohyperthermia. ( Gilly, FN; Glehen, O; Mohamed, F, 2004) |
| "For Dukes' C colon cancer, postoperative adjuvant chemotherapy with a combination of fluorouracil and levamisole is now recommended as standard therapy." | 2.39 | Adjuvant postoperative therapy of gastrointestinal malignancies. ( Ilson, DH; Kelsen, DP, 1994) |
| "Mitomycin and cisplatin were highly effective to prevent peritoneal carcinomatosis (direct application immediately after tumor cell transfer - 1 (st) treatment group)." | 1.32 | [Five cytostatic substances in animal studies for prevention and treatment of experimentally induced peritoneal carcinomatosis]. ( Fenske, A; Hribaschek, A; Krüger, S; Lippert, H; Meyer, F; Pross, M; Ridwelski, K, 2004) |
| "Mitomycin C was administered as a perfusate at 10 mg/l." | 1.32 | Treatment of peritoneal carcinomatosis in patients with digestive cancers with combination of intraperitoneal hyperthermia and mitomycin C. ( Banssillon, V; Bienvenu, J; Francois, Y; Garbit, F; Gilly, FN; Glehen, O; Grandclément, E; Panteix, G; Sadeghi-Looyeh, B; Sayag-Beaujard, AC; Vignal, J, 2004) |
| "This pharmacokinetic study attempted to improve the exposure of gastrointestinal tract tissues to chemotherapy by increasing the transit time of a first pass of a drug through the vascular system." | 1.29 | Pharmacokinetic studies of intraaortic stop-flow infusion with 14C-labeled mitomycin C. ( Averbach, AM; Fernandez-Trigo, V; Shamsa, F; Stephens, AD; Stuart, OA; Sugarbaker, PH; Sugarbaker, TA, 1995) |
| "5-Fluorouracil was given on postoperative days 2-5 at 15 and 20 mg/kg, respectively." | 1.28 | Early postoperative intraperitoneal chemotherapy as an adjuvant therapy to surgery for peritoneal carcinomatosis from gastrointestinal cancer: pharmacological studies. ( Cunliffe, WJ; DeBruijn, EA; Graves, T; Hull, WE; Mullins, RE; Oliff, L; Schlag, P; Sugarbaker, PH, 1990) |
| "For patients with breast cancer who had received extensive prior therapy, 3 mg/m2/day for 5 days repeated every 6-8 weeks were well-tolerated doses; and for patients with gastrointestinal cancer, the maximum-tolerated dose was 4 mg/m2/day." | 1.27 | A phase I-II study of continuous 5-day infusion mitomycin-C. ( Bedikian, A; Blumenschein, G; Hortobagyi, G; Valdivieso, M; Yap, HY, 1983) |
| "The mitomycin C dose was less than or equal to 15 mg/m2 every 53rd day and the total cumulative dose was between 25 and 250 mg." | 1.27 | Renal complications of mitomycin C therapy with special reference to the total dose. ( Nordman, E; Valavaara, R, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (30.56) | 18.7374 |
| 1990's | 29 (40.28) | 18.2507 |
| 2000's | 14 (19.44) | 29.6817 |
| 2010's | 5 (6.94) | 24.3611 |
| 2020's | 2 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X | 1 |
| Peng, F | 1 |
| Ji, Y | 1 |
| Xiang, H | 1 |
| Wang, X | 1 |
| Liu, T | 1 |
| Wang, H | 1 |
| Han, Y | 1 |
| Wang, C | 1 |
| Zhang, Y | 1 |
| Kong, X | 1 |
| Lang, JY | 1 |
| Ong, E | 1 |
| Diven, C | 1 |
| Abrams, A | 1 |
| Lee, E | 1 |
| Mahadevan, D | 1 |
| Abdul Aziz, NH | 1 |
| Wang, W | 1 |
| Teo, MC | 1 |
| Bhagwandin, S | 1 |
| Naffouje, S | 1 |
| Salti, G | 1 |
| Bekaii-Saab, T | 1 |
| Hill, M | 1 |
| Campbell, A | 1 |
| Kosuri, K | 1 |
| Thomas, J | 1 |
| Villalona-Calero, M | 1 |
| Rueth, NM | 1 |
| Murray, SE | 1 |
| Huddleston, SJ | 1 |
| Abbott, AM | 1 |
| Greeno, EW | 1 |
| Kirstein, MN | 1 |
| Tuttle, TM | 1 |
| Edmonson, JH | 1 |
| Marks, RS | 1 |
| Buckner, JC | 1 |
| Mahoney, MR | 1 |
| Takahashi, T | 3 |
| Glehen, O | 4 |
| Mithieux, F | 1 |
| Osinsky, D | 1 |
| Beaujard, AC | 2 |
| Freyer, G | 1 |
| Guertsch, P | 1 |
| Francois, Y | 3 |
| Peyrat, P | 1 |
| Panteix, G | 3 |
| Vignal, J | 3 |
| Gilly, FN | 4 |
| KAGEYAMA, T | 1 |
| MYHRE, K | 1 |
| FJAERLI, J | 1 |
| Hartmann, JT | 3 |
| Oechsle, K | 2 |
| Quietzsch, D | 1 |
| Wein, A | 1 |
| Hofheinz, RD | 3 |
| Honecker, F | 1 |
| Nehls, O | 1 |
| Köhne, CH | 1 |
| Käfer, G | 1 |
| Kanz, L | 1 |
| Bokemeyer, C | 2 |
| Whitehouse, PA | 1 |
| Mercer, SJ | 1 |
| Knight, LA | 1 |
| Di Nicolantonio, F | 1 |
| O'Callaghan, A | 1 |
| Cree, IA | 1 |
| Mohamed, F | 1 |
| Willer, A | 1 |
| Hartung, G | 1 |
| Gnad, U | 1 |
| Saussele, S | 1 |
| Kreil, S | 1 |
| Hehlmann, R | 1 |
| Hochhaus, A | 1 |
| Hribaschek, A | 1 |
| Pross, M | 1 |
| Ridwelski, K | 1 |
| Meyer, F | 1 |
| Fenske, A | 1 |
| Krüger, S | 1 |
| Lippert, H | 1 |
| Sayag-Beaujard, AC | 1 |
| Sadeghi-Looyeh, B | 1 |
| Bienvenu, J | 2 |
| Garbit, F | 2 |
| Grandclément, E | 2 |
| Banssillon, V | 1 |
| Sugarbaker, PH | 5 |
| Stuart, OA | 4 |
| Yoo, D | 1 |
| Beyer, U | 1 |
| Al-Batran, SE | 1 |
| Fujii, M | 1 |
| Murakami, N | 1 |
| Matsuka, Y | 1 |
| Ejiri, T | 1 |
| Asano, K | 1 |
| Yap, HY | 1 |
| Valdivieso, M | 1 |
| Blumenschein, G | 1 |
| Hortobagyi, G | 1 |
| Bedikian, A | 1 |
| Koga, S | 1 |
| Izumi, A | 1 |
| Maeta, M | 1 |
| Shimizu, N | 1 |
| Osaki, Y | 1 |
| Kanayama, H | 1 |
| Smith, BJ | 1 |
| Evans, M | 1 |
| Hellmann, K | 1 |
| Jones, R | 1 |
| Newton, K | 1 |
| Peters, N | 1 |
| Phillips, RH | 1 |
| Hagiwara, A | 1 |
| Ito, T | 1 |
| Hanna, WT | 1 |
| Krauss, S | 1 |
| Regester, RF | 1 |
| Murphy, WM | 1 |
| Simon, P | 1 |
| Hervé, JP | 1 |
| Ramée, MP | 1 |
| Leroy, JP | 1 |
| Ang, KS | 1 |
| Leguy, P | 1 |
| Vignoud, J | 1 |
| Cledes, J | 1 |
| Averbach, AM | 2 |
| Sugarbaker, TA | 2 |
| Stephens, AD | 3 |
| Fernandez-Trigo, V | 3 |
| Shamsa, F | 2 |
| Hashimoto, N | 1 |
| Kohno, H | 2 |
| Kubota, H | 1 |
| Hayashi, T | 1 |
| Uchida, M | 1 |
| Yamanoi, A | 1 |
| Ono, T | 1 |
| Nagasue, N | 2 |
| Kuzuya, T | 1 |
| Yamauchi, M | 2 |
| Ito, A | 2 |
| Hasegawa, M | 1 |
| Hasegawa, T | 1 |
| Nabeshima, T | 1 |
| Falk, SJ | 2 |
| Ramsay, JR | 3 |
| Ward, R | 2 |
| Miles, K | 1 |
| Dixon, AK | 1 |
| Bleehen, NM | 3 |
| Tetef, M | 1 |
| Margolin, K | 1 |
| Ahn, C | 1 |
| Akman, S | 1 |
| Chow, W | 1 |
| Coluzzi, P | 1 |
| Leong, L | 1 |
| Morgan, RJ | 1 |
| Raschko, J | 1 |
| Shibata, S | 1 |
| Seitz, JF | 1 |
| Diaw, A | 1 |
| Giovannini, M | 1 |
| Perrier, H | 1 |
| Gouvernet, J | 1 |
| Ilson, DH | 1 |
| Kelsen, DP | 1 |
| Yu, RC | 1 |
| Peng, XM | 1 |
| Rao, XQ | 1 |
| Satou, T | 1 |
| Dennis, IF | 1 |
| Workman, P | 2 |
| Tohda, S | 1 |
| Shiigai, T | 1 |
| Jibiki, M | 1 |
| Aoi, T | 1 |
| Ueda, Y | 1 |
| Kawasaki, T | 1 |
| Kurokawa, H | 1 |
| Nara, N | 1 |
| Yamaue, H | 1 |
| Tanimura, H | 1 |
| Hoover, LD | 1 |
| Loggie, BW | 3 |
| Perini, M | 1 |
| Fleming, RA | 3 |
| Russell, GB | 2 |
| Geisinger, K | 1 |
| Chung, YC | 1 |
| Huang, MT | 1 |
| Chang, CN | 1 |
| Huang, TW | 1 |
| Chen, MY | 1 |
| Chiles, C | 1 |
| Choplin, RH | 1 |
| Perini, MA | 1 |
| Caillot, JL | 1 |
| McQuellon, RP | 1 |
| Geisinger, KR | 1 |
| Gil-Delgado, MA | 1 |
| Antoine, EC | 1 |
| Guinet, F | 1 |
| Bassot, V | 1 |
| Grapin, JP | 1 |
| Benhammonda, A | 1 |
| Adam, R | 1 |
| Castaing, D | 1 |
| Bismuth, H | 1 |
| Khayat, D | 1 |
| Narasimha, K | 1 |
| Tabuchi, M | 1 |
| Takeda, T | 1 |
| Yakushiji, H | 1 |
| Hiroyoshi, M | 1 |
| Matsumoto, S | 1 |
| Fukawa, M | 1 |
| Imaizumi, N | 1 |
| Okushima, K | 1 |
| Dennis, I | 1 |
| Bedford, P | 1 |
| Wootton, R | 1 |
| Nethersell, AB | 1 |
| Sato, Y | 1 |
| Tohma, H | 1 |
| Shikama, T | 1 |
| Chang, YC | 1 |
| Nakamura, T | 1 |
| Yukaya, H | 1 |
| Ogawa, Y | 1 |
| Sasaki, K | 1 |
| Takahashi, M | 3 |
| Satta, T | 1 |
| Kondo, T | 1 |
| Takagi, H | 2 |
| Fujimura, T | 1 |
| Shima, Y | 1 |
| Sawasaki, K | 1 |
| Haryo, S | 1 |
| Fujita, H | 1 |
| Anada, E | 1 |
| Shiota, S | 1 |
| Nicolás, JM | 1 |
| Villalta, J | 1 |
| González-Clemente, JM | 1 |
| Antúnez, E | 1 |
| Almirall, J | 1 |
| Bosch, J | 1 |
| Torras, A | 1 |
| Urbano-Márquez, A | 1 |
| Graves, T | 1 |
| DeBruijn, EA | 1 |
| Cunliffe, WJ | 1 |
| Mullins, RE | 1 |
| Hull, WE | 1 |
| Oliff, L | 1 |
| Schlag, P | 1 |
| Jinushi, K | 1 |
| Hirabayashi, N | 2 |
| Kirihara, Y | 1 |
| Takagami, S | 1 |
| Ryuji, K | 1 |
| Yorishima, T | 1 |
| Nishiyama, M | 1 |
| Noso, Y | 1 |
| Toge, T | 1 |
| Sugihara, K | 1 |
| Auther, C | 1 |
| Mori, S | 1 |
| Nishihira, T | 1 |
| Matsumoto, T | 1 |
| Kawachi, S | 1 |
| Ishikawa, M | 1 |
| Nakajima, T | 1 |
| Kosaki, G | 1 |
| Hanyu, F | 1 |
| Nakamura, M | 1 |
| Takasaki, T | 1 |
| Kasai, Y | 1 |
| Sato, T | 1 |
| Sato, H | 1 |
| Sakurai, Y | 1 |
| Yamada, A | 1 |
| Okawa, T | 1 |
| Sakabe, T | 1 |
| Fujimoto, S | 1 |
| Shrestha, RD | 1 |
| Kokubun, M | 1 |
| Kobayashi, K | 1 |
| Kiuchi, S | 1 |
| Konno, C | 1 |
| Ohta, M | 1 |
| Koike, S | 1 |
| Kitsukawa, Y | 1 |
| Klapdor, R | 1 |
| Schwarzenberg, O | 1 |
| Kühl, JS | 1 |
| Franke, N | 1 |
| Bahlo, M | 1 |
| Ichihashi, H | 1 |
| Akiyama, S | 1 |
| Sakuyama, T | 1 |
| Kimura, A | 1 |
| Yoshida, S | 1 |
| Yanagisawa, S | 1 |
| Soji, K | 1 |
| Hano, H | 1 |
| Takahashi, N | 1 |
| Nagao, F | 1 |
| Brickner, TJ | 1 |
| Gilbertson, GF | 1 |
| Stone, WC | 1 |
| Misawa, S | 1 |
| Yashige, H | 1 |
| Nishigaki, H | 1 |
| Horiike, S | 1 |
| Tsuda, S | 1 |
| Abe, T | 1 |
| Takino, T | 1 |
| Taniwaki, M | 1 |
| Takeda, S | 1 |
| Tsuji, T | 1 |
| Becouarn, Y | 1 |
| Brunet, R | 1 |
| Bussières, E | 1 |
| Marée, D | 1 |
| Sakata, Y | 1 |
| Munakata, A | 1 |
| Baba, T | 1 |
| Saitoh, S | 1 |
| Itoh, T | 1 |
| Tamura, Y | 1 |
| Furukohori, N | 1 |
| Suzuki, H | 1 |
| Kimura, T | 1 |
| Kawata, K | 1 |
| Jarczok, K | 1 |
| Kardaszewicz, S | 1 |
| Luciak, M | 1 |
| Kubińska, E | 1 |
| Huzarski, J | 1 |
| Valavaara, R | 1 |
| Nordman, E | 1 |
| Kinami, Y | 1 |
| Takashima, S | 1 |
| Tanaka, T | 1 |
| Arizuka, S | 1 |
| Ashida, Y | 1 |
| Miyazaki, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Trial to Analyze Clinical and Pharmacological Properties for Severe Neutropenia After Cytoreductive Surgery Followed by Hyperthermic Intraperitoneal Chemotherapy Using Mitomycin-C[NCT05513183] | 74 participants (Actual) | Observational | 2021-05-20 | Completed | |||
| Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)[NCT05913674] | Phase 2 | 25 participants (Anticipated) | Interventional | 2023-07-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for mitomycin and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Peritoneal carcinomatosis from digestive tract cancer: new management by cytoreductive surgery and intraperitoneal chemohyperthermia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Gastro | 2004 |
Strategies for management of the peritoneal surface component of cancer: cytoreductive surgery plus perioperative intraperitoneal chemotherapy.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Combined Modality Therapy; Doxorubicin; Female; Fluor | 2005 |
Mitomycin C in the treatment of gastrointestinal tumours: recent data and perspectives.
Topics: Antibiotics, Antineoplastic; Clinical Trials as Topic; Gastrointestinal Neoplasms; Humans; Mitomycin | 2008 |
Adjuvant postoperative therapy of gastrointestinal malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined | 1994 |
[Paths of innovative surgery in gastrointestinal cancer in our department].
Topics: Antibodies, Monoclonal; Combined Modality Therapy; Drug Delivery Systems; Fluorouracil; Gastrointest | 1997 |
[Uremic hemolytic syndrome induced by mitomycin C. Presentation of a series of 5 cases and review of the literature].
Topics: Adenocarcinoma; Aged; Female; Gastrointestinal Neoplasms; Hemolytic-Uremic Syndrome; Humans; Male; M | 1990 |
24 trials available for mitomycin and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
A phase I dose escalation study of a pharmacobiologically based scheduling of capecitabine and mitomycin C in patients with gastrointestinal malignancies.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C | 2010 |
Severe electrolyte disturbances after hyperthermic intraperitoneal chemotherapy: oxaliplatin versus mitomycin C.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Clin | 2011 |
Contrast of response to dacarbazine, mitomycin, doxorubicin, and cisplatin (DMAP) plus GM-CSF between patients with advanced malignant gastrointestinal stromal tumors and patients with other advanced leiomyosarcomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Doxorubicin; Female; Gastr | 2002 |
Surgery combined with peritonectomy procedures and intraperitoneal chemohyperthermia in abdominal cancers with peritoneal carcinomatosis: a phase II study.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy | 2003 |
Protracted infusional 5-fluorouracil plus high-dose folinic acid combined with bolus mitomycin C in patients with gastrointestinal cancer: a phase I/II dose escalation study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sch | 2003 |
Capecitabine in combination with mitomycin C in patients with gastrointestinal cancer: results of an extended multicentre phase-I trial.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; De | 2004 |
[Efficacy of repeated hepatic dearterialization combined with intra-arterial infusion chemotherapy for unresectable tumors of the liver].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Doxorubi | 1995 |
Pharmacokinetic characteristics of 5-fluorouracil and mitomycin C in intraperitoneal chemotherapy.
Topics: Absorption; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Chromatog | 1994 |
BW12C perturbs normal and tumour tissue oxygenation and blood flow in man.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzaldehydes; Cohort Studies; Erythrocytes; Gastroi | 1994 |
Mitomycin C and menadione for the treatment of advanced gastrointestinal cancers: a phase II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Gastrointestinal Neoplasms; Hum | 1995 |
[Studies of guben quyu No I combined with chemotherapy in treating cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; CD4-CD8 Ratio; Cyclop | 1994 |
Pharmacokinetics of BW12C and mitomycin C, given in combination in a phase 1 study in patients with advanced gastrointestinal cancer.
Topics: Benzaldehydes; Drug Combinations; Drug Evaluation; Gastrointestinal Neoplasms; Half-Life; Humans; Me | 1993 |
Treatment and prevention of malignant ascites associated with disseminated intraperitoneal malignancies by aggressive combined-modality therapy.
Topics: Antibiotics, Antineoplastic; Ascites; Combined Modality Therapy; Female; Gastrointestinal Neoplasms; | 1997 |
Continuous hyperthermic peritoneal perfusion for peritoneal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusio | 1996 |
Thoracic complications in patients undergoing intraperitoneal heated chemotherapy with mitomycin following cytoreductive surgery.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Gastrointes | 1997 |
Intraperitoneal chemohyperthermia with mitomycin C for digestive tract cancer patients with peritoneal carcinomatosis.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma; Combined Modality Therapy; Equipment Design; Fe | 2000 |
Phase I-II study of irinotecan in combination with mitomycin C in patients with advanced gastrointestinal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Gastrointestinal | 2001 |
Phase I study of BW12C in combination with mitomycin C in patients with advanced gastrointestinal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzaldehydes; Drug Eva | 1992 |
[Chemotherapy for advanced and recurrent cancer patients--the effect of combination chemotherapy using cisplatin, peplomycin, mitomycin C, adriamycin, and 5-fluorouracil].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Colorectal Neopla | 1990 |
[Oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in repeated arterial bolus chemotherapy in metastatic liver cancer of humans--preliminary randomized trial].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Doxorub | 1991 |
[Early phase II study of the combined use of AO-90 methionine-free amino acid solution and anticancer agents (5-FU and MMC) in patients with advanced and recurrent gastrointestinal cancer. AO-90 Study group].
Topics: Adult; Aged; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; | 1990 |
[Clinical study of controlled-release preparation of mitomycin C in the treatment of inoperable cancer patients].
Topics: Clinical Trials as Topic; Delayed-Action Preparations; Dosage Forms; Gastrointestinal Neoplasms; Hum | 1988 |
[Controlled study of MQF-OK therapy with FT and with UFT on various advanced gastrointestinal cancers. Hirosaki Cooperative Study Group of Cancer Chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Clinical Trials as Top | 1988 |
42 other studies available for mitomycin and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Brca2 deficiency drives gastrointestinal tumor formation and is selectively inhibited by mitomycin C.
Topics: Animals; BRCA2 Protein; Gastrointestinal Neoplasms; Humans; Mice; Mitomycin | 2020 |
Laparoscopic hyperthermic intraperitoneal chemotherapy (HIPEC) for palliative treatment of malignant ascites from gastrointestinal stromal tumours.
Topics: Aged; Antibiotics, Antineoplastic; Ascites; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tum | 2012 |
Scrotal pain and ulceration post HIPEC: a case report.
Topics: Adult; Cytoreduction Surgical Procedures; Gastrointestinal Neoplasms; Genital Diseases, Male; Humans | 2015 |
Utility of Chemoresponse Assay in Patients Undergoing Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytoreductio | 2015 |
Development and clinical application of drug delivery systems for cancer treatment.
Topics: Aged; Antineoplastic Agents; Carbon; Combined Modality Therapy; Drug Delivery Systems; Emulsions; Fe | 2002 |
PAPER ELECTROPHORETIC STUDIES ON SERUM PROTEINS IN THE DISEASES OF THE DIGESTIVE SYSTEM, WITH PARTICULAR REFERENCE TO THE CHANGES IN SERUM PROTEINS IN THE PATIENTS WITH CANCER.
Topics: Antineoplastic Agents; Blood Protein Electrophoresis; Blood Proteins; Carcinoma, Hepatocellular; Dig | 1963 |
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
Topics: Biomedical Research; Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Esophageal Neoplasms; Female | 1964 |
Combination chemotherapy in advanced gastrointestinal cancers: ex vivo sensitivity to gemcitabine and mitomycin C.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug | 2003 |
[Five cytostatic substances in animal studies for prevention and treatment of experimentally induced peritoneal carcinomatosis].
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplasti | 2004 |
Treatment of peritoneal carcinomatosis in patients with digestive cancers with combination of intraperitoneal hyperthermia and mitomycin C.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Ascites; Carcinoma; Combined Modality Therapy; Female; Gas | 2004 |
[Chemotherapy of gastrointestinal cancer in elderly patients--evaluation of combination therapy with mitomycin C and 5-fluorouracil].
Topics: Aged; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Colonic Neoplasms; Drug Synergism; Dru | 1983 |
A phase I-II study of continuous 5-day infusion mitomycin-C.
Topics: Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Drug Evaluation; Female; Gastrointestinal Neopl | 1983 |
The effects of total-body hyperthermia combined with anticancer drugs on immunity in advanced cancer patients.
Topics: Adult; Antineoplastic Agents; Complement System Proteins; Cyclophosphamide; Doxorubicin; Female; Fev | 1983 |
Inefficacy of dacarbazine, mitomycin C, and hepatic irradiation in patients with metastatic adenocarcinoma of the gastrointestinal tract.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera | 1984 |
[Intraabdominal administration of MMC adsorbed on activated carbon for management of carcinomatous peritonitis].
Topics: Abdomen; Carbon; Colonic Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Middle Aged; Mitomyc | 1984 |
Renal disease after mitomycin C therapy.
Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Aged; Blood Pressure; Blood Urea Nitrogen; Creatinine; F | 1981 |
[Mytomycin C nephrotoxicity. 3 new cases and review of the literature].
Topics: Adenocarcinoma; Carcinoid Tumor; Creatinine; Female; Gastrointestinal Neoplasms; Humans; Kidney Dise | 1982 |
Intraaortic stop-flow infusion: pharmacokinetic feasibility study of regional chemotherapy for unresectable gastrointestinal cancers.
Topics: Animals; Antibiotics, Antineoplastic; Aorta; Chemotherapy, Cancer, Regional Perfusion; Dogs; Gastroi | 1995 |
Pharmacokinetic studies of intraaortic stop-flow infusion with 14C-labeled mitomycin C.
Topics: Animals; Aorta, Abdominal; Carbon Radioisotopes; Dogs; Drug Delivery Systems; Gastrointestinal Neopl | 1995 |
[5-fluorouracil, high dose folinic acid and mitomycin C in the treatment of advanced digestive cancers].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug | 1994 |
[Importance of systemic administration of pyrimidine after thermochemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Fluorouracil; Gas | 1993 |
[Three cases of drug-induced hemolytic uremic syndrome].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Fluorouracil; Gastrointest | 1996 |
[Effects of chemotherapy on the basis of the results of MTT assay for patients with gastrointestinal cancer].
Topics: Antineoplastic Agents; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorour | 1995 |
Surgically directed chemotherapy: heated intraperitoneal lavage with mitomycin C.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Gastrointestinal Neopla | 1996 |
Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of gastrointestinal origin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Chem | 2000 |
Chemotherapy of solid tumors in private practice in Malaysia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Drug | 1992 |
[Intermittent intra-arterial infusion chemotherapy using implantable reservoir for the treatment of hepatic metastasis].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Do | 1992 |
A feasibility study of the SDI test for the evaluation of gastrointestinal cancer sensitivity to anticancer drugs.
Topics: Animals; Antineoplastic Agents; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Feasibilit | 1991 |
[Prophylactic effect of allopurinol mouthwash against stomatitis induced by the chemotherapy (PMUE regimen) for gastrointestinal malignancies].
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Gastroint | 1991 |
Early postoperative intraperitoneal chemotherapy as an adjuvant therapy to surgery for peritoneal carcinomatosis from gastrointestinal cancer: pharmacological studies.
Topics: Chromatography, High Pressure Liquid; Combined Modality Therapy; Fluorouracil; Gastrointestinal Neop | 1990 |
[Clinical studies of in vitro chemosensitivity test evaluated by ATP assay of gastrointestinal cancer].
Topics: Adenosine Triphosphate; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Scree | 1990 |
Clinical trial with surgery and intraperitoneal hyperthermic perfusion for peritoneal recurrence of gastrointestinal cancer.
Topics: Adult; Blood Proteins; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Female; | 1989 |
Effects of MAb BW 494/32 and rTNF-a/rIFN-g alone and in combination in nude mice bearing xenografts of human gastrointestinal/pancreatic carcinomas.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Gastrointestinal Neoplasms; Humans; Interfer | 1989 |
Correlation of an in vitro chemosensitivity test using [3H] incorporation with the response in case of human tumor chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carbazilquinone; Colony-Forming Units Assay; Cytarabine; Dactino | 1986 |
[Experimental and clinical studies on chemosensitivity tests of anticancer agents by human tumor clonogenic assay].
Topics: Antineoplastic Agents; Colony-Forming Units Assay; Drug Evaluation, Preclinical; Gastrointestinal Ne | 1986 |
[Clinical results of CDDP, MMC and 5-FU combination chemotherapy in advanced or recurrent gastrointestinal cancers].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule | 1987 |
Concurrent combined chemotherapy and radiation therapy in gastrointestinal cancers.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Gastrointestinal Neoplasms; Human | 1987 |
[Evaluation of a combination of UFT, MMC, and OK-432 for advanced gastro-intestinal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Gastrointestinal Neop | 1987 |
5-Fluorouracil, high-dose folinic acid, and mitomycin C combination chemotherapy in advanced gastrointestinal adenocarcinomas. A pilot study.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; | 1988 |
[Analysis of the course and treatment of primary non-Hodgkin's lymphoma of the gastrointestinal tract].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophospha | 1987 |
Renal complications of mitomycin C therapy with special reference to the total dose.
Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Female; | 1985 |
[Intra-arterial continuous infusion in patients with advanced and recurrent cancer of the digestive system].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Co | 1985 |