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mitomycin and Cancer of Duodenum

mitomycin has been researched along with Cancer of Duodenum in 11 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"(1) To determine the toxicity of an intensified postoperative adjuvant regimen for periampullary adenocarcinoma (pancreatic and nonpancreatic) utilizing concurrent 5-fluorouracil (5-FU), leucovorin (LV), dipyridamole (DPM), and mitomycin-C (MMC) combined with split-course locoregional external beam radiotherapy (EBRT) to 50 Gy."3.70Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival. ( Abrams, RA; Cameron, JL; Chakravarthy, A; Donehower, RC; Grochow, LB; Hruban, RH; Hurwitz, H; Jaffee, EM; Korman, LT; Lillemoe, KD; O'Reilly, S; Yeo, CJ; Zahurek, ML, 2000)
"Chemoradiation for duodenal cancer has produced a complete pathologic response in all patients and survival has been excellent, suggesting efficacy of this regimen for duodenal cancer."2.67Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum. ( Coia, L; Eisenberg, B; Hanks, G; Hoffman, J; Paul, A; Scher, R; Solin, L; Weese, J; Weiner, L, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's5 (45.45)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Soma, I1
Hasuike, Y1
Hayashi, N1
Fukuchi, N1
Izawa, H1
Yoshida, T1
Ebisui, C1
Sakita, I1
Fujimoto, T1
Koshino, T1
Izumiyama, K1
Gibson, MK1
Holcroft, CA1
Kvols, LK1
Haller, D1
Coia, L1
Hoffman, J1
Scher, R1
Weese, J1
Solin, L1
Weiner, L1
Eisenberg, B1
Paul, A1
Hanks, G1
Yeung, RS1
Weese, JL1
Hoffman, JP1
Solin, LJ1
Paul, AR1
Engstrom, PF1
Litwin, S1
Kowalyshyn, MJ1
Eisenberg, BL1
Ozaki, H1
Kinoshita, T1
Kosuge, T1
Yamamoto, J1
Shimada, K1
Inoue, K1
Koyama, Y1
Mukai, K1
Chakravarthy, A1
Abrams, RA1
Yeo, CJ1
Korman, LT1
Donehower, RC1
Hruban, RH1
Zahurek, ML1
Grochow, LB1
O'Reilly, S1
Hurwitz, H1
Jaffee, EM1
Lillemoe, KD1
Cameron, JL1
Ishizaki, M1
Akiyama, N1
Tanaka, S1
Motegi, M1
Sasamoto, H1
Osawa, H1
Wada, W1
Nakajima, M1
Hashimoto, T1
Araki, H1
Yoshioka, T1
Yasui, K1
Kodama, M1
Wagner, A1
Waitz, W1
Neumann, R1
Common, H1
Ricken, D1
Suda, Y1
Sekine, T1

Trials

3 trials available for mitomycin and Cancer of Duodenum

ArticleYear
Phase II study of 5-fluorouracil, doxorubicin, and mitomycin C for metastatic small bowel adenocarcinoma.
    The oncologist, 2005, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Duodenal Neoplas

2005
Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum.
    International journal of radiation oncology, biology, physics, 1994, Aug-30, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

1994
Neoadjuvant chemoradiation in pancreatic and duodenal carcinoma. A Phase II Study.
    Cancer, 1993, Oct-01, Volume: 72, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Chemotherapy, Adjuvant; Combined Modality Therapy; Duodenal Neoplasms;

1993

Other Studies

8 other studies available for mitomycin and Cancer of Duodenum

ArticleYear
[A case report--Efficacy of combination therapy to unresectable advanced gall bladder carcinoma--palliative operation, hepatic arterial infusion therapy, and radiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Combined

2004
An aggressive therapeutic approach to carcinoma of the body and tail of the pancreas.
    Cancer, 1996, Jun-01, Volume: 77, Issue:11

    Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Combined Modality Therapy; Duod

1996
Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival.
    International journal of radiation oncology, biology, physics, 2000, Nov-01, Volume: 48, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2000
[Long-term survival of a patient with postoperative liver metastasis of stage IVa gallbladder cancer responding to hepatic arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:3

    Topics: Adenocarcinoma; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; C

2001
[A case of multiple pulmonary metastases from duodenal cancer showing partial response using 5'-DFUR and a small dose of MMC].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:14

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Duodenal Neoplasms; Female; Fl

1992
[Intratumoral injection of mitomycin for adenocarcinoma of the duodenum].
    Deutsche medizinische Wochenschrift (1946), 1990, May-11, Volume: 115, Issue:19

    Topics: Adenocarcinoma; Aged; Duodenal Neoplasms; Humans; Injections, Intralesional; Male; Mitomycin; Mitomy

1990
[Metastasizing primary duodenal cancer. Extended remission in a patient following chemotherapy].
    Onkologie, 1986, Volume: 9, Issue:5

    Topics: Adenocarcinoma, Papillary; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality T

1986
[Biliary and pancreatic excretion of mitomycin C, with special reference to the concomitant use of urokinase].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Bile; Duodenal Neoplasms; Humans; Mitomycin; Mitomycins; Pancreatic Juice; Pancreatic Neoplasms; Uro

1985