mitomycin has been researched along with Burns, Chemical in 18 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Burns, Chemical: Burns caused by contact with or exposure to CAUSTICS or strong ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitomycin C application significantly reduced the number of dilatation sessions needed to alleviate dysphagia in patients with caustic esophageal strictures." | 9.17 | Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebo-controlled trial. ( Abdelkader, HM; El-Asmar, KM; Hamza, AF; Hassan, MA, 2013) |
| "The aim of this study was to investigate the efficacy and safety of endoscopic local infiltration of mitomycin C (MMC) after oesophageal dilation for children suffering from refractory postcorrosive oesophageal stricture (OS)." | 7.91 | Short-term Effects of Mitomycin C Infiltration for Caustic Oesophageal Strictures in Children. ( Abdullateef, KS; Arafa, A; Elkadi, R; Mansour, O; Mohamed, W; Qinawy, M; Raslan, H; Seleim, H; Wishahy, AMK; Yassin, T, 2019) |
| "There was a highly significant difference in the improvement of dysphagia grade at the end of follow up in the mitomycin C group (p=0." | 7.81 | A prospective controlled study to assess the use of mitomycin C in improving the results of esophageal dilatation in post corrosive esophageal stricture in children. ( Ezzat, WF; Fawaz, SA; Sabri, SM; Sweed, AS, 2015) |
| " In 12 patients of caustic induced esophageal stricture, who failed to respond despite rigorous dilatation regimen for more than one year, a trial of topical mitomycin-C application to improve dilatation results was undertaken, considering the recently reported efficacy and safety of this agent." | 7.80 | Mitomycin-C: 'a ray of hope' in refractory corrosive esophageal strictures. ( Katiyar, P; Nagaich, N; Nijhawan, S; Rathore, M; Sharma, R, 2014) |
| "We comparative effects of mitomycin-c and heparin which have different mechanism of action in a minimal invasive corrosive esophagitis model which was formed by NaOH 40%." | 7.77 | Comparison of mitomycin-c and heparin affects in experimental corrosive esophagitis on rats. ( Pabuscu, E; Sen, S; Senturk, E; Unsal, C, 2011) |
| " We report the successful use of mitomycin C in a young boy in whom we could achieve ongoing relief of dysphagia after the unsuccessful long-term use of frequent endoscopic dilatations." | 7.74 | [Topical mitomycin C treatment of a benign oesophageal stricture following caustic ingestion in a four-year-old boy]. ( Fröhlich, T; Greess, H; Köhler, H, 2007) |
| "We describe a novel technique of endoluminal delivery and focused application of mitomycin-C to an esophageal stricture that avoids inadvertent topical application to adjacent mucosa." | 7.74 | Topical mitomycin-C for recalcitrant esophageal strictures: a novel endoscopic/fluoroscopic technique for safe endoluminal delivery. ( Baird, R; Blair, GK; Heran, MK; Skarsgard, ED, 2008) |
| "Mitomycin C application significantly reduced the number of dilatation sessions needed to alleviate dysphagia in patients with caustic esophageal strictures." | 5.17 | Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebo-controlled trial. ( Abdelkader, HM; El-Asmar, KM; Hamza, AF; Hassan, MA, 2013) |
| "The aim of this study was to investigate the efficacy and safety of endoscopic local infiltration of mitomycin C (MMC) after oesophageal dilation for children suffering from refractory postcorrosive oesophageal stricture (OS)." | 3.91 | Short-term Effects of Mitomycin C Infiltration for Caustic Oesophageal Strictures in Children. ( Abdullateef, KS; Arafa, A; Elkadi, R; Mansour, O; Mohamed, W; Qinawy, M; Raslan, H; Seleim, H; Wishahy, AMK; Yassin, T, 2019) |
| "There was a highly significant difference in the improvement of dysphagia grade at the end of follow up in the mitomycin C group (p=0." | 3.81 | A prospective controlled study to assess the use of mitomycin C in improving the results of esophageal dilatation in post corrosive esophageal stricture in children. ( Ezzat, WF; Fawaz, SA; Sabri, SM; Sweed, AS, 2015) |
| " In 12 patients of caustic induced esophageal stricture, who failed to respond despite rigorous dilatation regimen for more than one year, a trial of topical mitomycin-C application to improve dilatation results was undertaken, considering the recently reported efficacy and safety of this agent." | 3.80 | Mitomycin-C: 'a ray of hope' in refractory corrosive esophageal strictures. ( Katiyar, P; Nagaich, N; Nijhawan, S; Rathore, M; Sharma, R, 2014) |
| "We comparative effects of mitomycin-c and heparin which have different mechanism of action in a minimal invasive corrosive esophagitis model which was formed by NaOH 40%." | 3.77 | Comparison of mitomycin-c and heparin affects in experimental corrosive esophagitis on rats. ( Pabuscu, E; Sen, S; Senturk, E; Unsal, C, 2011) |
| " We report the successful use of mitomycin C in a young boy in whom we could achieve ongoing relief of dysphagia after the unsuccessful long-term use of frequent endoscopic dilatations." | 3.74 | [Topical mitomycin C treatment of a benign oesophageal stricture following caustic ingestion in a four-year-old boy]. ( Fröhlich, T; Greess, H; Köhler, H, 2007) |
| "We describe a novel technique of endoluminal delivery and focused application of mitomycin-C to an esophageal stricture that avoids inadvertent topical application to adjacent mucosa." | 3.74 | Topical mitomycin-C for recalcitrant esophageal strictures: a novel endoscopic/fluoroscopic technique for safe endoluminal delivery. ( Baird, R; Blair, GK; Heran, MK; Skarsgard, ED, 2008) |
| " The purpose of this study was to investigate the effectiveness of Mitomycin C (MMC), which inhibits fibroblastic proliferation in preventing caustic esophageal strictures." | 3.73 | Mitomycin C prevents strictures in caustic esophageal burns in rats. ( Başaklar, AC; Demirtola, A; Dinçer, S; Gülen, S; Kale, N; Karabulut, R; Poyraz, A; Sönmez, K; Türkyilmaz, Z, 2005) |
| "Mitomycin C is a chemotherapeutic agent known to suppress fibroblast proliferation." | 1.34 | The effect of topical mitomycin C on full-thickness burns. ( Dick, E; Helling, ER; Lyons, RC; Tennyson, H; Wiseman, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 10 (55.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Wishahy, AMK | 1 |
| Seleim, H | 1 |
| Qinawy, M | 1 |
| Mohamed, W | 1 |
| Mansour, O | 1 |
| Abdullateef, KS | 1 |
| Elkadi, R | 1 |
| Raslan, H | 1 |
| Arafa, A | 1 |
| Yassin, T | 1 |
| Hoffman, RS | 1 |
| Burns, MM | 1 |
| Gosselin, S | 1 |
| Ghobrial, CM | 1 |
| Eskander, AE | 1 |
| Nagaich, N | 1 |
| Nijhawan, S | 1 |
| Katiyar, P | 1 |
| Sharma, R | 1 |
| Rathore, M | 1 |
| El-Asmar, KM | 3 |
| Hassan, MA | 2 |
| Abdelkader, HM | 2 |
| Hamza, AF | 2 |
| Sweed, AS | 1 |
| Fawaz, SA | 1 |
| Ezzat, WF | 1 |
| Sabri, SM | 1 |
| Shub, MD | 1 |
| Türkyilmaz, Z | 2 |
| Sönmez, K | 2 |
| Karabulut, R | 2 |
| Gülbahar, O | 1 |
| Poyraz, A | 2 |
| Sancak, B | 1 |
| Başaklar, AC | 2 |
| Senturk, E | 1 |
| Pabuscu, E | 1 |
| Sen, S | 1 |
| Unsal, C | 1 |
| Bustamante, TF | 1 |
| Lourenção, PL | 1 |
| Higa, KL | 1 |
| Silva, AP | 1 |
| Ortolan, EV | 1 |
| Demirtola, A | 1 |
| Gülen, S | 1 |
| Dinçer, S | 1 |
| Kale, N | 1 |
| Olutoye, OO | 1 |
| Shulman, RJ | 1 |
| Cotton, RT | 1 |
| Fröhlich, T | 1 |
| Greess, H | 1 |
| Köhler, H | 1 |
| Tennyson, H | 1 |
| Helling, ER | 1 |
| Wiseman, J | 1 |
| Dick, E | 1 |
| Lyons, RC | 1 |
| Heran, MK | 1 |
| Baird, R | 1 |
| Blair, GK | 1 |
| Skarsgard, ED | 1 |
| Afzal, NA | 1 |
| Albert, D | 1 |
| Thomas, AL | 1 |
| Thomson, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children[NCT04524897] | Phase 4 | 20 participants (Anticipated) | Interventional | 2020-12-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mitomycin and Burns, Chemical
| Article | Year |
|---|---|
Ingestion of Caustic Substances.
Topics: Acids; Adult; Alkalies; Burns, Chemical; Caustics; Child; Endoscopy, Digestive System; Esophageal Pe | 2020 |
Therapy of caustic ingestion: new treatment considerations.
Topics: Accidents; Alkylating Agents; Burns, Chemical; Caustics; Child; Child, Preschool; Dilatation; Esopha | 2015 |
3 trials available for mitomycin and Burns, Chemical
| Article | Year |
|---|---|
Topical Mitomycin C application for esophageal stricture: safe, precise, and novel endoscopic technique.
Topics: Administration, Topical; Alkylating Agents; Burns, Chemical; Catheters; Child; Combined Modality The | 2013 |
Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebo-controlled trial.
Topics: Administration, Topical; Burns, Chemical; Caustics; Child, Preschool; Double-Blind Method; Esophagea | 2013 |
Topical mitomycin C can effectively alleviate dysphagia in children with long-segment caustic esophageal strictures.
Topics: Administration, Topical; Alkylating Agents; Burns, Chemical; Caustics; Child, Preschool; Deglutition | 2015 |
13 other studies available for mitomycin and Burns, Chemical
| Article | Year |
|---|---|
Short-term Effects of Mitomycin C Infiltration for Caustic Oesophageal Strictures in Children.
Topics: Burns, Chemical; Child; Dilatation; Esophageal Stenosis; Esophagoscopy; Female; Humans; Male; Mitomy | 2019 |
Prospective study of the effect of topical application of Mitomycin C in refractory pediatric caustic esophageal strictures.
Topics: Administration, Topical; Adolescent; Alkylating Agents; Burns, Chemical; Caustics; Child; Child, Pre | 2018 |
Mitomycin-C: 'a ray of hope' in refractory corrosive esophageal strictures.
Topics: Administration, Topical; Antibiotics, Antineoplastic; Burns, Chemical; Deglutition Disorders; Dilata | 2014 |
A prospective controlled study to assess the use of mitomycin C in improving the results of esophageal dilatation in post corrosive esophageal stricture in children.
Topics: Administration, Topical; Antibiotics, Antineoplastic; Burns, Chemical; Caustics; Child; Child, Presc | 2015 |
Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats.
Topics: Administration, Topical; Alkalies; Animals; Antibiotics, Antineoplastic; Burns, Chemical; Disease Mo | 2009 |
Comparison of mitomycin-c and heparin affects in experimental corrosive esophagitis on rats.
Topics: Alkylating Agents; Animals; Burns, Chemical; Caustics; Disease Models, Animal; Esophagitis; Female; | 2011 |
The use of mitomycin C in caustic esophagitis in rats.
Topics: Animals; Burns, Chemical; Caustics; Dilatation; Disease Models, Animal; Esophageal Stenosis; Male; M | 2013 |
Mitomycin C prevents strictures in caustic esophageal burns in rats.
Topics: Alkalies; Animals; Antibiotics, Antineoplastic; Body Weight; Burns, Chemical; Disease Models, Animal | 2005 |
Mitomycin C in the management of pediatric caustic esophageal strictures: a case report.
Topics: Burns, Chemical; Esophageal Stenosis; Humans; Infant; Male; Mitomycin | 2006 |
[Topical mitomycin C treatment of a benign oesophageal stricture following caustic ingestion in a four-year-old boy].
Topics: Administration, Topical; Burns, Chemical; Caustics; Child, Preschool; Deglutition Disorders; Esophag | 2007 |
The effect of topical mitomycin C on full-thickness burns.
Topics: Administration, Topical; Animals; Burns, Chemical; Chlorhexidine; Disease Models, Animal; Disinfecta | 2007 |
Topical mitomycin-C for recalcitrant esophageal strictures: a novel endoscopic/fluoroscopic technique for safe endoluminal delivery.
Topics: Administration, Topical; Adult; Burns, Chemical; Catheterization; Child, Preschool; Deglutition Diso | 2008 |
A child with oesophageal strictures.
Topics: Burns, Chemical; Caustics; Dilatation; Esophageal Stenosis; Female; Humans; Infant; Mitomycin | 2002 |