mitomycin has been researched along with Burkitt Lymphoma in 8 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Burkitt Lymphoma: A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| " Similarly, constitutive hTERT expression inhibited wild-type p53-dependent apoptosis in response to mitomycin C or 5-fluorouracil in HCT116 colon carcinoma cells carrying endogenous p53." | 3.73 | hTERT antagonizes p53-induced apoptosis independently of telomerase activity. ( Latonen, L; Rahman, R; Wiman, KG, 2005) |
| "Mitomycin C sensitivity was confirmed in an hMLH1-defective clone derived from Raji cells and in msh2-defective mouse embryo fibroblasts derived from knock-out mice." | 1.31 | Sensitivity to DNA cross-linking chemotherapeutic agents in mismatch repair-defective cells in vitro and in xenografts. ( Aquilina, G; Bignami, M; Colussi, C; Crescenzi, M; Fiumicino, S; Leonetti, C; Martinelli, S, 2000) |
| "Mitomycin C treated tumor cell suspensions, when cocultured with normal human blood leukocytes, markedly depressed the expected blastogenic responses in vitro to concanavalin A, pokeweed mitogen, and phytohemagglutin." | 1.27 | Lymphoblastoid cell-induced suppression of human peripheral blood leukocyte mitogenic responses. ( Friedman, F; Friedman, H; Hsu, KH; Nonoyama, M; Specter, S; Zhang, JL, 1984) |
| " In this study we have examined the cytokinetic effects of this drug combination in vitro and in human bone marrow in vivo." | 1.26 | Cytokinetic evaluation of the four-drug combination of bleomycin, vincristine, mitomycin C, and methotrexate (BOMM) in cultured Burkitt's lymphoma cells and human bone marrow. ( Clauw, DJ; Ensminger, WD; O'Toole, TE; Wheeler, RH, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| NGU, VA | 1 |
| Rahman, R | 1 |
| Latonen, L | 1 |
| Wiman, KG | 1 |
| Shah, R | 1 |
| Beem, E | 1 |
| Sautina, L | 1 |
| Zharikov, SI | 1 |
| Segal, MS | 1 |
| Zhang, JL | 1 |
| Friedman, F | 1 |
| Hsu, KH | 1 |
| Specter, S | 1 |
| Friedman, H | 1 |
| Nonoyama, M | 1 |
| Wheeler, RH | 1 |
| Clauw, DJ | 1 |
| O'Toole, TE | 1 |
| Ensminger, WD | 1 |
| Okano, M | 1 |
| Fiumicino, S | 1 |
| Martinelli, S | 1 |
| Colussi, C | 1 |
| Aquilina, G | 1 |
| Leonetti, C | 1 |
| Crescenzi, M | 1 |
| Bignami, M | 1 |
1 review available for mitomycin and Burkitt Lymphoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
1 trial available for mitomycin and Burkitt Lymphoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
7 other studies available for mitomycin and Burkitt Lymphoma
| Article | Year |
|---|---|
THE CHEMOTHERAPY OF CANCER. (A PRELIMINARY REPORT OF ITS SCOPE IN WEST AFRICA).
Topics: Africa; Africa, Western; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic A | 1964 |
hTERT antagonizes p53-induced apoptosis independently of telomerase activity.
Topics: Apoptosis; Burkitt Lymphoma; Carcinoma; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA-Bind | 2005 |
Mitomycin- and calcineurin-associated HUS, endothelial dysfunction and endothelial repair: a new paradigm for the puzzle?
Topics: Adenocarcinoma; Adult; Antibiotics, Antineoplastic; Antigens, CD34; Biomarkers; Burkitt Lymphoma; Ca | 2007 |
Lymphoblastoid cell-induced suppression of human peripheral blood leukocyte mitogenic responses.
Topics: Animals; Burkitt Lymphoma; Callitrichinae; Cell Line; Cell Transformation, Viral; Cell-Free System; | 1984 |
Cytokinetic evaluation of the four-drug combination of bleomycin, vincristine, mitomycin C, and methotrexate (BOMM) in cultured Burkitt's lymphoma cells and human bone marrow.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Burki | 1982 |
High susceptibility of an Epstein-Barr virus-converted Burkitt's lymphoma cell line to cytotoxic drugs.
Topics: Antineoplastic Agents; Burkitt Lymphoma; Cell Division; Cell Line; Cell Transformation, Viral; Cytar | 1997 |
Sensitivity to DNA cross-linking chemotherapeutic agents in mismatch repair-defective cells in vitro and in xenografts.
Topics: Adenosine Triphosphatases; Animals; Base Pair Mismatch; Burkitt Lymphoma; Cell Division; Cross-Linki | 2000 |