mitomycin has been researched along with Bloom Syndrome in 4 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Bloom Syndrome: An autosomal recessive disorder characterized by telangiectatic ERYTHEMA of the face, photosensitivity, DWARFISM and other abnormalities, and a predisposition toward developing cancer. The Bloom syndrome gene (BLM) encodes a RecQ-like DNA helicase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Werner's syndrome (WS) and Bloom's syndrome (BS) are rare autosomal genetic diseases that predispose to cancer and are associated with genomic instability." | 1.31 | Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients. ( Furuichi, Y; Goto, M; Hayashi, M; Honma, M; Sakamoto, H; Satoh, T; Sofuni, T; Sugimoto, M; Tadokoro, S; Tanabe, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Honma, M | 1 |
| Tadokoro, S | 1 |
| Sakamoto, H | 1 |
| Tanabe, H | 1 |
| Sugimoto, M | 1 |
| Furuichi, Y | 1 |
| Satoh, T | 1 |
| Sofuni, T | 1 |
| Goto, M | 1 |
| Hayashi, M | 1 |
| Latt, SA | 1 |
| Schreck, RR | 1 |
| D'Andrea, A | 1 |
| Kaiser, TN | 1 |
| Schlesinger, F | 1 |
| Lester, S | 1 |
| Sakai, K | 1 |
| Shiraishi, Y | 1 |
| Miyagi, T | 1 |
| Miwa, M | 1 |
| Sandberg, AA | 1 |
| Gibbons, B | 1 |
| Scott, D | 1 |
| Hungerford, JL | 1 |
| Cheung, KL | 1 |
| Harrison, C | 1 |
| Attard-Montalto, S | 1 |
| Evans, M | 1 |
| Birch, JM | 1 |
| Kingston, JE | 1 |
4 other studies available for mitomycin and Bloom Syndrome
| Article | Year |
|---|---|
Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients.
Topics: 4-Nitroquinoline-1-oxide; B-Lymphocytes; Bloom Syndrome; Camptothecin; Carcinogens; Case-Control Stu | 2002 |
Detection, significance, and mechanism of sister chromatid exchange formation: past experiments, current concepts, future challenges.
Topics: Animals; Bloom Syndrome; Bromodeoxyuridine; Cells, Cultured; Chromosomes; Cricetinae; Cricetulus; DN | 1984 |
Effects of temperature on sister chromatid exchange in Bloom syndrome cells.
Topics: Animals; Antibiotics, Antineoplastic; Bloom Syndrome; Cells, Cultured; Cricetinae; Crossing Over, Ge | 1982 |
Retinoblastoma in association with the chromosome breakage syndromes Fanconi's anaemia and Bloom's syndrome: clinical and cytogenetic findings.
Topics: Bloom Syndrome; Child, Preschool; Chromosome Aberrations; Chromosomes; DNA; Eye Neoplasms; Fanconi A | 1995 |