mitomycin has been researched along with Bleb in 55 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of sodium hyaluronate eye drops for prevention of late-onset bleb leakage after trabeculectomy with mitomycin C (MMC)." | 9.13 | Sodium hyaluronate eye drops prevent late-onset bleb leakage after trabeculectomy with mitomycin C. ( Fujiwara, T; Iida, T; Koizumi, H; Sagara, H; Suzuki, K; Yago, K, 2008) |
| "To investigate the potential of colchicine to improve bleb function after trabeculectomy." | 7.91 | The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits. ( Akaishi, T; Kokubun, T; Nakamura, M; Nakazawa, T; Omodaka, K; Sato, K; Shiga, Y; Shimazaki, A; Tsuda, S; Yamamoto, K, 2019) |
| " The triamcinolone + mitomycin C acetate group presented better indices as for the maximum bleb height and vascularization of the bleb central area (p=0." | 7.88 | Healing modulation in glaucoma surgery after application of subconjunctival triamcinolone acetate alone or combined with mitomycin C: an experimetal study. ( Araújo, ID; Cronemberger, S; Rangel, HMDA; Rolim, HT; Vidigal, P, 2018) |
| "To determine if sequential treatment with Bevacizumab (Avastin), a monoclonal, VEGF antibody that blocks angiogenesis; Saratin, a 12 kD polypeptide with anti-inflammatory and anti-thrombotic properties; and Ilomastat, a matrix metalloproteinase (MMP) inhibitor, prolongs bleb life following glaucoma filtration surgery (GFS) in a rabbit model." | 7.81 | Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model. ( Levine, MA; Lukowski, ZL; Martorana, GM; Meyers, CA; Min, J; Schaefer, JL; Schultz, GS; Sherwood, MB, 2015) |
| "To compare the effects of silver nanoparticles (AgNPs) and mitomycin C (MMC) on intraocular pressure (IOP) and external, histologic, and immunohistochemical bleb characteristics in a rabbit model of filtration surgery." | 7.79 | Topical silver nanoparticles result in improved bleb function by increasing filtration and reducing fibrosis in a rabbit model of filtration surgery. ( Butler, MR; Chevez-Barrios, P; Frankfort, BJ; Orengo-Nania, S; Prospero Ponce, CM; Weinstock, YE, 2013) |
| "To compare the histopathologic and morphologic findings of encapsulated blebs following Ahmed glaucoma valve implantation and primary standard trabeculectomy with mitomycin-C." | 7.78 | Comparative study of encapsulated blebs following Ahmed glaucoma valve implantation and trabeculectomy with mitomycin-C. ( Bae, K; Kee, C; Suh, W, 2012) |
| "To investigate the relationship between intrascleral bleb height and intraocular pressure (IOP) following deep sclerectomy with collagen implant (DSCI) and mitomycin C (MMC) in eyes with clinically flat blebs." | 7.76 | Postoperative IOP is related to intrascleral bleb height in eyes with clinically flat blebs following deep sclerectomy with collagen implant and mitomycin. ( Mavrakanas, N; Mendrinos, E; Shaarawy, T, 2010) |
| "To analyse clinical outcomes of trabeculectomy with mitomycin C (MMC) in eyes with uveitic glaucoma (UG) with inactive uveitis and compare them to those in eyes with primary open-angle glaucoma (POAG)." | 7.75 | Initial trabeculectomy with mitomycin C in eyes with uveitic glaucoma with inactive uveitis. ( Araie, M; Kaburaki, T; Kawashima, H; Koshino, T; Numaga, J; Shirato, S; Tomidokoro, A, 2009) |
| "Two patients developed bleb-related ocular infection attributable to Gemella haemolysans and Gemella morbillorum after trabeculectomy with adjunctive mitomycin C." | 7.75 | Gemella species-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C. ( Katada, T; Kawakami, H; Mikamo, H; Mochizuki, K; Sawada, A; Watanabe, K; Yamamoto, T, 2009) |
| "Antimetabolites, especially mitomycin C (MMC), increase the incidence of late bleb-related endophthalmitis in trabeculectomy." | 7.73 | Determinants of bleb morphology in minimally invasive, clear-cornea micropenetrating glaucoma surgery with mitomycin C. ( Flesner, P; Jensen, PK; Kessing, SV, 2006) |
| "To prospectively study the evolution of possible high risk features of conjunctival filtration blebs like avascularity, transconjunctival oozing (TCO), and leaks after mitomycin C (MMC) enhanced glaucoma surgery." | 7.73 | Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks. ( Anand, N; Arora, S; Clowes, M, 2006) |
| "Diode laser application with G-probe appears to be a useful modality of treatment for ocular hypotony and overfiltering blebs resulting from trabeculectomy with mitomycin-C." | 5.12 | Effect of diode laser application with G-probe on ocular hypotony after trabeculectomy with mitomycin-C. ( Abdollahi, A; Amini, H; Ghaffary, E; Razeghinejad, MR, 2006) |
| "To investigate the potential of colchicine to improve bleb function after trabeculectomy." | 3.91 | The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits. ( Akaishi, T; Kokubun, T; Nakamura, M; Nakazawa, T; Omodaka, K; Sato, K; Shiga, Y; Shimazaki, A; Tsuda, S; Yamamoto, K, 2019) |
| "The objective of this study is to investigate the results of an adaptive approach of bleb revision surgery for late onset hypotony after trabeculectomy with mitomycin C because of bleb leakage and/or scleral melting." | 3.88 | Results of an Adaptive Surgical Approach for Managing Late Onset Hypotony After Trabeculectomy With Mitomycin C. ( Hoffmann, EM; Lamparter, J; Pfeiffer, N; Prokosch-Willing, V; Toshev, AP; Ul Hassan, SN, 2018) |
| " The triamcinolone + mitomycin C acetate group presented better indices as for the maximum bleb height and vascularization of the bleb central area (p=0." | 3.88 | Healing modulation in glaucoma surgery after application of subconjunctival triamcinolone acetate alone or combined with mitomycin C: an experimetal study. ( Araújo, ID; Cronemberger, S; Rangel, HMDA; Rolim, HT; Vidigal, P, 2018) |
| "To examine outcomes of trabeculectomy with mitomycin C for uncontrolled glaucoma when performed by glaucoma trainee surgeons." | 3.85 | Primary Trabeculectomy Outcomes by Glaucoma Fellows in a Tertiary Hospital in Brazil. ( Abe, RY; Costa, VP; Shigueoka, LS; Vasconcellos, JPC, 2017) |
| "To compare two surgical approaches for treating encapsulated blebs after trabeculectomy with mitomycin C, in terms of the development of intraocular pressure and progression of glaucoma in a long-term follow up: 1." | 3.85 | Revision of encapsulated blebs after trabeculectomy: Long-term comparison of standard bleb needling and modified needling procedure combined with transconjunctival scleral flap sutures. ( Culmann, PD; Grus, FH; Hoffmann, EM; Laspas, P; Pfeiffer, N; Poplawksi, A; Prokosch-Willing, V, 2017) |
| "To determine if sequential treatment with Bevacizumab (Avastin), a monoclonal, VEGF antibody that blocks angiogenesis; Saratin, a 12 kD polypeptide with anti-inflammatory and anti-thrombotic properties; and Ilomastat, a matrix metalloproteinase (MMP) inhibitor, prolongs bleb life following glaucoma filtration surgery (GFS) in a rabbit model." | 3.81 | Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model. ( Levine, MA; Lukowski, ZL; Martorana, GM; Meyers, CA; Min, J; Schaefer, JL; Schultz, GS; Sherwood, MB, 2015) |
| "Twelve filtering blebs of 8 patients were included: 4 cases of trabeculectomy without mitomycin C (MMC), 6 cases of trabeculectomy with MMC, and 2 cases of non-penetrating glaucoma surgery." | 3.80 | [Evaluation of conjunctival epithelium of filtering blebs by impression cytology]. ( Buetas, P; González, S; López, S; Matias-Guiu, X; Muniesa, MJ; Sánchez, C, 2014) |
| "To compare the effects of silver nanoparticles (AgNPs) and mitomycin C (MMC) on intraocular pressure (IOP) and external, histologic, and immunohistochemical bleb characteristics in a rabbit model of filtration surgery." | 3.79 | Topical silver nanoparticles result in improved bleb function by increasing filtration and reducing fibrosis in a rabbit model of filtration surgery. ( Butler, MR; Chevez-Barrios, P; Frankfort, BJ; Orengo-Nania, S; Prospero Ponce, CM; Weinstock, YE, 2013) |
| "To analyse blebs of phacotrabeculectomies performed with Ologen collagen implants (ProTop & MediKing, Taipei, Taiwan) and to compare these with blebs of mitomycin C (MMC)–augmented phacotrabeculectomies." | 3.77 | Imaging of blebs after phacotrabeculectomy with Ologen collagen matrix implants. ( Aung, T; Boey, PY; Htoon, HM; Narayanaswamy, A; Perera, SA; Seah, SK; Tun, TA; Wong, TT; Zheng, C, 2011) |
| "We report on a patient with an overhanging bleb several years following trabeculectomy surgery with mitomycin C." | 3.77 | Dramatic dysesthetic overhanging bleb. ( Kapoor, KG; Syed, MF, 2011) |
| "To investigate the relationship between intrascleral bleb height and intraocular pressure (IOP) following deep sclerectomy with collagen implant (DSCI) and mitomycin C (MMC) in eyes with clinically flat blebs." | 3.76 | Postoperative IOP is related to intrascleral bleb height in eyes with clinically flat blebs following deep sclerectomy with collagen implant and mitomycin. ( Mavrakanas, N; Mendrinos, E; Shaarawy, T, 2010) |
| "Two eyes of 2 patients status postfornix-based trabeculectomy with mitomycin C were found to have symptomatic circumferential blebs." | 3.76 | Application of handheld cautery for reduction of symptomatic circumferential trabeculectomy blebs. ( Albano, M; Schwartz, AL, 2010) |
| " We compare and contrast the histopathology of a normally functioning mitomycin-C trabeculectomy site obtained from an eye enucleated for iris melanoma with abnormal blebs discussed in the literature." | 3.75 | Histopathology of a functioning mitomycin-C trabeculectomy. ( Lee, GA; Liang, SY; Whitehead, K, 2009) |
| "Two patients developed bleb-related ocular infection attributable to Gemella haemolysans and Gemella morbillorum after trabeculectomy with adjunctive mitomycin C." | 3.75 | Gemella species-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C. ( Katada, T; Kawakami, H; Mikamo, H; Mochizuki, K; Sawada, A; Watanabe, K; Yamamoto, T, 2009) |
| "To analyse clinical outcomes of trabeculectomy with mitomycin C (MMC) in eyes with uveitic glaucoma (UG) with inactive uveitis and compare them to those in eyes with primary open-angle glaucoma (POAG)." | 3.75 | Initial trabeculectomy with mitomycin C in eyes with uveitic glaucoma with inactive uveitis. ( Araie, M; Kaburaki, T; Kawashima, H; Koshino, T; Numaga, J; Shirato, S; Tomidokoro, A, 2009) |
| "To compare the effects of variable mitomycin-C (MMC) applications during trabeculectomy on target intraocular pressure (IOP), number of antiglaucomatous therapy, bleb morphology and surgical complications." | 3.74 | Enhancement of the success rate in trabeculectomy: large-area mitomycin-C application. ( Aktaş, Z; Hasanreisoğlu, B; Onol, M, 2008) |
| "The mid-term appearance of the filtering bleb and surgical outcome following tunnel-trabeculectomy, in which protective measures were carried out to avoid contact between the mitomycin C (MMC) and the conjunctival flap, are presented." | 3.74 | Protection of the conjunctival flap from contact with mitomycin C during tunnel-trabeculectomy. ( Karatas, M; Ophir, A, 2007) |
| "To investigate the comparative efficacy and safety of deep sclerectomy with and without intraoperative mitomycin C (MMC) application for lowering the intraocular pressure (IOP)." | 3.73 | Deep sclerectomy augmented with mitomycin C. ( Anand, N; Atherley, C, 2005) |
| "To prospectively study the evolution of possible high risk features of conjunctival filtration blebs like avascularity, transconjunctival oozing (TCO), and leaks after mitomycin C (MMC) enhanced glaucoma surgery." | 3.73 | Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks. ( Anand, N; Arora, S; Clowes, M, 2006) |
| "Antimetabolites, especially mitomycin C (MMC), increase the incidence of late bleb-related endophthalmitis in trabeculectomy." | 3.73 | Determinants of bleb morphology in minimally invasive, clear-cornea micropenetrating glaucoma surgery with mitomycin C. ( Flesner, P; Jensen, PK; Kessing, SV, 2006) |
| "The primary endpoint measured was bleb morphology and vascularity using the Moorfields Bleb Grading System." | 2.75 | Bleb morphology and vascularity after trabeculectomy with intravitreal ranibizumab: a pilot study. ( Kahook, MY, 2010) |
| "The filtering blebs were evaluated clinically and with SL-OCT on day 1 and 1, 2, 4 and 12 weeks following surgery." | 2.73 | A pilot study on slit lamp-adapted optical coherence tomography imaging of trabeculectomy filtering blebs. ( Keunen, JE; Klevering, BJ; Theelen, T; Wesseling, P, 2007) |
| "Main postoperative complications were transient: 4 eyes with seidel phenomenon at 24 hours (10." | 1.46 | Two-year Results After Deep Sclerectomy With Nonabsorbable Uveoscleral Implant (Esnoper-Clip): Surgical Area Analysis Using Anterior Segment Optical Coherence Tomography. ( Castellvi-Manent, J; Loscos-Arenas, J; Moll-Udina, A; Romanic-Bubalo, N; Romera-Romero, P; Valldeperas, X, 2017) |
| "Secondary glaucoma is a serious complication in patients with transthyretin (TTR)-related familial amyloidotic polyneuropathy (FAP)." | 1.40 | Long-term outcomes and complications of trabeculectomy for secondary glaucoma in patients with familial amyloidotic polyneuropathy. ( Ando, Y; Eiki, D; Hara, R; Inoue, T; Kawaji, T; Tanihara, H, 2014) |
| "The meiboscores of the bleb-contacting upper eyelid areas were significantly higher than those for the bleb-noncontacting upper eyelid areas (P < 0." | 1.40 | Meibomian gland loss due to trabeculectomy. ( Horikiri, H; Noji, H; Ogasawara, M; Sagara, H; Sekiryu, T; Sugano, Y, 2014) |
| "the Wuerzburg bleb classification score (WBCS) aims at an objective and standardized assessment of the developing filtering bleb after trabeculectomy, in order to detect and treat bleb scarring at the earliest possible stage of development." | 1.37 | The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy. ( Ellinger, P; Grehn, F; Guthoff, R; Kann, G; Klink, J; Klink, T, 2011) |
| "Filtering blebs with various types of glaucoma were examined using Stratus OCT." | 1.36 | Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap. ( Baba, T; Hirooka, K; Shiraga, F; Takagishi, M; Takenaka, H, 2010) |
| "Postoperative complications were: ocular hypotony (1 case), bleb fibrosis (2 cases), bleb-related endophthalmitis (1 case)." | 1.36 | [Non-pentrating deep sclerectomy--between safety and efficacy]. ( Cantemir, A; Chiseliţă, D; Ilieş, I, 2010) |
| "Bleb wall reflectivity of developing blebs on AS-OCT 2 weeks postoperatively was correlated with mature bleb function at 6-month postoperative visit." | 1.36 | Early trabeculectomy bleb walls on anterior-segment optical coherence tomography. ( Hangai, M; Hirose, F; Inoue, R; Nakanishi, H; Nakano, N; Ojima, T; Unoki, N; Yoshimura, N, 2010) |
| "Visualization of filtering bleb structure in vivo is an objective and helpful method of evaluation of functioning status following trabeculectomy." | 1.35 | [Evaluation on the cellular level the filtering bleb following trabeculectomy, using the HRT II Cornea Module]. ( Jurowska-Liput, J; Krzyzanowska, P; Nizankowska, MH; Szelepin, Ł, 2008) |
| "SDOCT showed the bleb cavity (23." | 1.35 | High-definition imaging of trabeculectomy blebs using spectral domain optical coherence tomography adapted for the anterior segment. ( Aquino, MC; Chew, PT; See, JL; Singh, M; Thean, LS, 2009) |
| "Thirty-one blebs of 24 patients underwent noncontact in vivo confocal microscopy using the Rostock Cornea Module of the Heidelberg Retina Tomograph II (50x noncontact Nikon lens, 1-2 mum resolution, field of view: 500x500 mum)." | 1.35 | Noncontact in vivo scanning laser microscopy of filtering blebs. ( Liebmann, JM; Palmiero, PM; Ritch, R; Sbeity, Z; Tello, C, 2009) |
| "No patients presented recurrence of the bleb leak or AMT-related complications during entire follow-up." | 1.35 | Long-term results of amniotic membrane transplantation-assisted bleb revision for leaking blebs. ( Fujioka, M; Nagai-Kusuhara, A; Nakamura, M; Negi, A, 2008) |
| "Within this group, blebs were classified into three different categories according to their optical coherence tomography pattern: type A (featuring a thick wall and a single large fluid-filled space), type B (featuring a thin wall and multiple large fluid-filled spaces) and type C (featuring multiple, irregular and flattened fluid-filled spaces)." | 1.33 | Filtering blebs imaging by optical coherence tomography. ( Barboni, P; Savini, G; Zanini, M, 2005) |
| "Twenty-four glaucoma filtering blebs in 24 eyes of 17 patients." | 1.33 | Comparison of two clinical Bleb grading systems. ( Ashraff, NN; Hall, RC; Purdie, G; Wells, AP, 2006) |
| "Each bleb was incised segmentally and the cut edges of the conjunctiva and Tenon capsule were sutured to the underlying sclera." | 1.33 | Surgical reduction of symptomatic, circumferential, filtering blebs. ( Anis, S; Liebmann, J; Ritch, R; Shihadeh, W, 2006) |
| "Two additional filtering blebs were treated with balanced saline solution (BSS), two received mitomycin-C (MMC) (0." | 1.33 | A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis). ( Sherwood, MB, 2006) |
| "Clinically, it appears as vesiculobullous lesions of the oral cavity and eyes, but other tissues such as the nasopharyngeal and laryngeal mucosa can also be affected." | 1.32 | Mucous membrane pemphigoid: nasal and laryngeal manifestations. ( Ali, I; Capper, JW; Martinez Devesa, P; Whiteside, OJ, 2003) |
| "To report delayed-onset, bleb-associated endophthalmitis caused by Lecythophora mutabilis." | 1.32 | Delayed-onset, bleb-associated endophthalmitis caused by Lecythophora mutabilis. ( Cruz-Villegas, V; Flynn, HW; Miller, D; Scott, IU, 2004) |
| "To assess the efficacy of a bleb revision technique with regard to improvement in intraocular pressure (IOP) and visual acuity after hypotony maculopathy and to evaluate the influence of duration of hypotony on visual outcome." | 1.32 | Bleb revision for hypotony maculopathy after trabeculectomy. ( Bashford, KP; Shafranov, G; Shields, MB, 2004) |
| "In the study 6 patients with cystic blebs after trabeculectomy with mitomycin C was presented." | 1.32 | [Surgical management of pathologic filtering blebs in pediatric glaucoma]. ( Chipczyńska, B; Grałek, M; Kanigowska, K; Klimczak-Slaczka, D, 2004) |
| "Late bleb leaks may follow months to years after filtering surgery especially with the use of antimetabolites." | 1.31 | [Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps]. ( Ayed, T; Hamard, H; Hamard, P; Quesnot, S; Tazartes, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 28 (50.91) | 29.6817 |
| 2010's | 26 (47.27) | 24.3611 |
| 2020's | 1 (1.82) | 2.80 |
| Authors | Studies |
|---|---|
| Grover, DS | 1 |
| Kornmann, HL | 1 |
| Fellman, RL | 1 |
| Laspas, P | 1 |
| Culmann, PD | 1 |
| Grus, FH | 1 |
| Prokosch-Willing, V | 2 |
| Poplawksi, A | 1 |
| Pfeiffer, N | 2 |
| Hoffmann, EM | 2 |
| Abe, RY | 1 |
| Shigueoka, LS | 1 |
| Vasconcellos, JPC | 1 |
| Costa, VP | 1 |
| Romera-Romero, P | 1 |
| Loscos-Arenas, J | 1 |
| Moll-Udina, A | 1 |
| Romanic-Bubalo, N | 1 |
| Castellvi-Manent, J | 1 |
| Valldeperas, X | 1 |
| Lamparter, J | 1 |
| Ul Hassan, SN | 1 |
| Toshev, AP | 1 |
| Rangel, HMDA | 1 |
| Rolim, HT | 1 |
| Vidigal, P | 1 |
| Araújo, ID | 1 |
| Cronemberger, S | 1 |
| Kokubun, T | 1 |
| Yamamoto, K | 1 |
| Sato, K | 1 |
| Akaishi, T | 1 |
| Shimazaki, A | 1 |
| Nakamura, M | 2 |
| Shiga, Y | 1 |
| Tsuda, S | 1 |
| Omodaka, K | 1 |
| Nakazawa, T | 1 |
| Butler, MR | 1 |
| Prospero Ponce, CM | 1 |
| Weinstock, YE | 1 |
| Orengo-Nania, S | 1 |
| Chevez-Barrios, P | 1 |
| Frankfort, BJ | 1 |
| Kawaji, T | 1 |
| Inoue, T | 1 |
| Hara, R | 1 |
| Eiki, D | 1 |
| Ando, Y | 1 |
| Tanihara, H | 1 |
| Muniesa, MJ | 1 |
| González, S | 1 |
| Buetas, P | 1 |
| López, S | 1 |
| Sánchez, C | 1 |
| Matias-Guiu, X | 1 |
| Sagara, H | 2 |
| Sekiryu, T | 1 |
| Noji, H | 1 |
| Ogasawara, M | 1 |
| Sugano, Y | 1 |
| Horikiri, H | 1 |
| Martorana, GM | 1 |
| Schaefer, JL | 1 |
| Levine, MA | 1 |
| Lukowski, ZL | 1 |
| Min, J | 1 |
| Meyers, CA | 1 |
| Schultz, GS | 1 |
| Sherwood, MB | 2 |
| Onol, M | 1 |
| Aktaş, Z | 1 |
| Hasanreisoğlu, B | 1 |
| Hirooka, K | 2 |
| Takagishi, M | 2 |
| Baba, T | 2 |
| Takenaka, H | 1 |
| Shiraga, F | 2 |
| Lee, E | 1 |
| Doyle, E | 1 |
| Jenkins, C | 1 |
| Jurowska-Liput, J | 1 |
| Krzyzanowska, P | 1 |
| Szelepin, Ł | 1 |
| Nizankowska, MH | 1 |
| Prata, TS | 1 |
| De Moraes, CG | 1 |
| Palmiero, PM | 2 |
| Tello, C | 2 |
| Liebmann, J | 2 |
| Ritch, R | 3 |
| Okuda, T | 1 |
| Higashide, T | 1 |
| Fukuhira, Y | 1 |
| Sumi, Y | 1 |
| Shimomura, M | 1 |
| Sugiyama, K | 1 |
| Budenz, DL | 1 |
| Radcliffe, N | 1 |
| Blumenthal, EZ | 1 |
| Liang, SY | 1 |
| Lee, GA | 1 |
| Whitehead, K | 1 |
| Kaburaki, T | 1 |
| Koshino, T | 1 |
| Kawashima, H | 1 |
| Numaga, J | 1 |
| Tomidokoro, A | 1 |
| Shirato, S | 1 |
| Araie, M | 1 |
| Singh, M | 1 |
| See, JL | 1 |
| Aquino, MC | 1 |
| Thean, LS | 1 |
| Chew, PT | 1 |
| Sbeity, Z | 1 |
| Liebmann, JM | 1 |
| Sawada, A | 1 |
| Mochizuki, K | 1 |
| Katada, T | 1 |
| Kawakami, H | 1 |
| Yamamoto, T | 1 |
| Mikamo, H | 1 |
| Watanabe, K | 1 |
| Carpineto, P | 1 |
| Agnifili, L | 1 |
| Nubile, M | 1 |
| Fasanella, V | 1 |
| Doronzo, E | 1 |
| Mastropasqua, A | 1 |
| Ciancaglini, M | 1 |
| Schwartz, AL | 1 |
| Albano, M | 1 |
| Nakano, N | 1 |
| Hangai, M | 1 |
| Nakanishi, H | 1 |
| Inoue, R | 1 |
| Unoki, N | 1 |
| Hirose, F | 1 |
| Ojima, T | 1 |
| Yoshimura, N | 1 |
| Mavrakanas, N | 1 |
| Mendrinos, E | 1 |
| Shaarawy, T | 1 |
| Chiseliţă, D | 1 |
| Cantemir, A | 1 |
| Ilieş, I | 1 |
| Kahook, MY | 1 |
| Boey, PY | 1 |
| Narayanaswamy, A | 1 |
| Zheng, C | 1 |
| Perera, SA | 1 |
| Htoon, HM | 1 |
| Tun, TA | 1 |
| Seah, SK | 1 |
| Wong, TT | 1 |
| Aung, T | 1 |
| Klink, T | 1 |
| Kann, G | 1 |
| Ellinger, P | 1 |
| Klink, J | 1 |
| Grehn, F | 1 |
| Guthoff, R | 1 |
| Sen, E | 1 |
| Balikoglu-Yilmaz, M | 1 |
| Bozdag-Pehlivan, S | 1 |
| Sungu, N | 1 |
| Aksakal, FN | 1 |
| Altinok, A | 1 |
| Tuna, T | 1 |
| Unlu, N | 1 |
| Ustun, H | 1 |
| Koklu, G | 1 |
| Öztürk, F | 1 |
| Gonçalves, ED | 1 |
| Paris, Fdos S | 1 |
| Gomes, JÁ | 1 |
| Kanecadan, L | 1 |
| Campos, M | 1 |
| Kapoor, KG | 1 |
| Syed, MF | 1 |
| Bae, K | 1 |
| Suh, W | 1 |
| Kee, C | 1 |
| Whiteside, OJ | 1 |
| Martinez Devesa, P | 1 |
| Ali, I | 1 |
| Capper, JW | 1 |
| Scott, IU | 1 |
| Cruz-Villegas, V | 1 |
| Flynn, HW | 1 |
| Miller, D | 1 |
| Bashford, KP | 1 |
| Shafranov, G | 1 |
| Shields, MB | 1 |
| O'Brart, DP | 1 |
| Shiew, M | 1 |
| Edmunds, B | 1 |
| Klimczak-Slaczka, D | 1 |
| Grałek, M | 1 |
| Chipczyńska, B | 1 |
| Kanigowska, K | 1 |
| Anand, N | 2 |
| Atherley, C | 1 |
| Savini, G | 1 |
| Zanini, M | 1 |
| Barboni, P | 1 |
| Wells, AP | 1 |
| Ashraff, NN | 1 |
| Hall, RC | 1 |
| Purdie, G | 1 |
| Arora, S | 1 |
| Clowes, M | 1 |
| Kessing, SV | 1 |
| Flesner, P | 1 |
| Jensen, PK | 1 |
| Ophir, A | 1 |
| Karatas, M | 1 |
| Anis, S | 1 |
| Shihadeh, W | 1 |
| Theelen, T | 1 |
| Wesseling, P | 1 |
| Keunen, JE | 1 |
| Klevering, BJ | 1 |
| Iida, T | 1 |
| Suzuki, K | 1 |
| Fujiwara, T | 1 |
| Koizumi, H | 1 |
| Yago, K | 1 |
| Amini, H | 1 |
| Razeghinejad, MR | 1 |
| Ghaffary, E | 1 |
| Abdollahi, A | 1 |
| Nagai-Kusuhara, A | 1 |
| Fujioka, M | 1 |
| Negi, A | 1 |
| Hamard, P | 1 |
| Tazartes, M | 1 |
| Ayed, T | 1 |
| Quesnot, S | 1 |
| Hamard, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Occlusion Prevention for Trabeculectomy Procedures Using Combination Ranibizumab and Mitomycin C (MMC) During Surgery (OCTOPUS Study)[NCT00661583] | Phase 1/Phase 2 | 30 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| Anterior Segment Optical Coherence Tomography Findings in Patients With Ahmed Glaucoma Drainage Implants With Either a Pericardial Patch Graft and Fibrin Tissue Glue or a Partial-Thickness Scleral Flap and Conventional Sutures[NCT00453024] | Phase 2 | 40 participants (Anticipated) | Interventional | 2007-02-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To assess ocular adverse events of combination ranibizumab and MMC therapy at 6 months (NCT00661583)
Timeframe: 6 months
| Intervention | Number of Reported Adverse Events (Number) |
|---|---|
| Ranibizumab Alone | 0 |
| Ranibizumab and MMC | 0 |
| MMC Alone | 0 |
To determine percent of subjects with a qualified success and viable bleb at 6 months (IOP between 6mm Hg and 22 mm Hg with pressure controlled with and without adjunctive medications) (NCT00661583)
Timeframe: 6 months
| Intervention | percentage of subjects (Number) |
|---|---|
| Ranibizumab Alone | 100 |
| Ranibizumab and MMC | 100 |
| MMC Alone | 100 |
Mean change in in intraocular pressure at 3 months and at 6 months (NCT00661583)
Timeframe: 6 months
| Intervention | mmHg (Mean) | |
|---|---|---|
| month 3 minus baseline | month 6 minus baseline | |
| MMC Alone | -8.35 | -8.00 |
| Ranibizumab Alone | -6.40 | -6.60 |
| Ranibizumab and MMC | -6.40 | -4.90 |
Mean change in visual acuity in logMAR. (NCT00661583)
Timeframe: 6 months
| Intervention | logMAR (Mean) | |
|---|---|---|
| Month 3 minus baseline | Month 6 minus baseline | |
| MMC Alone | 0.13 | 0.13 |
| Ranibizumab Alone | -0.01 | -0.05 |
| Ranibizumab and MMC | 0.01 | 0.05 |
7 trials available for mitomycin and Bleb
| Article | Year |
|---|---|
Bleb morphology and vascularity after trabeculectomy with intravitreal ranibizumab: a pilot study.
Topics: Aged; Alkylating Agents; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Hu | 2010 |
Effect of doxycycline on postoperative scarring after trabeculectomy in an experimental rabbit model.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blister; Cicatrix; Conjunctiva; Doxycyc | 2010 |
Bullous keratopathy.
Topics: Blister; Combined Modality Therapy; Corneal Diseases; Corneal Transplantation; Eye Pain; Follow-Up S | 2011 |
A randomised, prospective study comparing trabeculectomy with viscocanalostomy with adjunctive antimetabolite usage for the management of open angle glaucoma uncontrolled by medical therapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Cataract; Female; Filtering Surgery; Fluor | 2004 |
A pilot study on slit lamp-adapted optical coherence tomography imaging of trabeculectomy filtering blebs.
Topics: Aged; Alkylating Agents; Aqueous Humor; Blister; Conjunctiva; Diagnostic Techniques, Ophthalmologica | 2007 |
Sodium hyaluronate eye drops prevent late-onset bleb leakage after trabeculectomy with mitomycin C.
Topics: Adult; Aged; Aqueous Humor; Blister; Epithelium, Corneal; Female; Follow-Up Studies; Humans; Hyaluro | 2008 |
Effect of diode laser application with G-probe on ocular hypotony after trabeculectomy with mitomycin-C.
Topics: Adolescent; Adult; Alkylating Agents; Blister; Feasibility Studies; Female; Humans; Laser Therapy; M | 2006 |
48 other studies available for mitomycin and Bleb
| Article | Year |
|---|---|
Response to letter to the Editor Regarding MMC and pH.
Topics: Blister; Filtering Surgery; Glaucoma; Humans; Hydrogen-Ion Concentration; Intraocular Pressure; Mito | 2020 |
Revision of encapsulated blebs after trabeculectomy: Long-term comparison of standard bleb needling and modified needling procedure combined with transconjunctival scleral flap sutures.
Topics: Antibiotics, Antineoplastic; Blister; Conjunctiva; Female; Follow-Up Studies; Humans; Intraocular Pr | 2017 |
Primary Trabeculectomy Outcomes by Glaucoma Fellows in a Tertiary Hospital in Brazil.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Blister; Brazil; Education, Medical, Graduate; Fe | 2017 |
Two-year Results After Deep Sclerectomy With Nonabsorbable Uveoscleral Implant (Esnoper-Clip): Surgical Area Analysis Using Anterior Segment Optical Coherence Tomography.
Topics: Aged; Aged, 80 and over; Anterior Eye Segment; Antibiotics, Antineoplastic; Antihypertensive Agents; | 2017 |
Results of an Adaptive Surgical Approach for Managing Late Onset Hypotony After Trabeculectomy With Mitomycin C.
Topics: Adult; Aged; Aged, 80 and over; Blister; Combined Modality Therapy; Female; Glaucoma; Humans; Intrao | 2018 |
Healing modulation in glaucoma surgery after application of subconjunctival triamcinolone acetate alone or combined with mitomycin C: an experimetal study.
Topics: Animals; Anti-Inflammatory Agents; Blister; Conjunctiva; Disease Models, Animal; Drug Therapy, Combi | 2018 |
The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits.
Topics: Alkylating Agents; Animals; Blister; Colchicine; Drug Therapy, Combination; Eye Diseases; Male; Mito | 2019 |
Topical silver nanoparticles result in improved bleb function by increasing filtration and reducing fibrosis in a rabbit model of filtration surgery.
Topics: Administration, Topical; Analysis of Variance; Animals; Anti-Infective Agents, Local; Antibiotics, A | 2013 |
Long-term outcomes and complications of trabeculectomy for secondary glaucoma in patients with familial amyloidotic polyneuropathy.
Topics: Adult; Aged; Blister; Female; Glaucoma; Humans; Intraocular Pressure; Kaplan-Meier Estimate; Male; M | 2014 |
[Evaluation of conjunctival epithelium of filtering blebs by impression cytology].
Topics: Aged; Aged, 80 and over; Aqueous Humor; Blister; Conjunctival Diseases; Conjunctivitis; Cytological | 2014 |
Meibomian gland loss due to trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Blister; Conjunctiva; Cross-Sectional Studies; Ey | 2014 |
Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model.
Topics: Analysis of Variance; Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Bevacizumab; Bl | 2015 |
Enhancement of the success rate in trabeculectomy: large-area mitomycin-C application.
Topics: Aged; Blister; Glaucoma; Humans; Incidence; Intraocular Pressure; Intraoperative Care; Middle Aged; | 2008 |
Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap.
Topics: Adult; Aged; Aged, 80 and over; Blister; Conjunctiva; Exfoliation Syndrome; Female; Glaucoma; Glauco | 2010 |
Trabeculectomy surgery augmented with intra-Tenon injection of mitomycin C.
Topics: Aged; Blister; Choroid Diseases; Cysts; Eye Diseases; Glaucoma; Humans; Hyphema; Injections; Intraoc | 2008 |
[Evaluation on the cellular level the filtering bleb following trabeculectomy, using the HRT II Cornea Module].
Topics: Aqueous Humor; Blister; Epithelial Cells; Glaucoma, Open-Angle; Humans; Microscopy, Confocal; Mitomy | 2008 |
Slit-lamp-adapted optical coherence tomography for assessment of an overhanging filtering bleb.
Topics: Aged; Alkylating Agents; Blister; Combined Modality Therapy; Conjunctival Diseases; Diagnostic Techn | 2010 |
A thin honeycomb-patterned film as an adhesion barrier in an animal model of glaucoma filtration surgery.
Topics: Absorbable Implants; Animals; Blister; Conjunctival Diseases; Disease Models, Animal; Filtering Surg | 2009 |
Late-onset bleb leakage.
Topics: Aged; Blister; Fluorescein; Glaucoma; Humans; Intraocular Pressure; Male; Mitomycin; Ocular Hypotens | 2009 |
Histopathology of a functioning mitomycin-C trabeculectomy.
Topics: Anterior Eye Segment; Blister; Eye Enucleation; Glaucoma; Humans; Iris Neoplasms; Male; Melanoma; Mi | 2009 |
Correlation between optical coherence tomography scan and histological specimen of a filtering bleb.
Topics: Animals; Aqueous Humor; Blister; Conjunctiva; Disease Models, Animal; Female; Filtering Surgery; His | 2010 |
Initial trabeculectomy with mitomycin C in eyes with uveitic glaucoma with inactive uveitis.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Blister; Combined Modality Therapy; Education, Medical, Co | 2009 |
High-definition imaging of trabeculectomy blebs using spectral domain optical coherence tomography adapted for the anterior segment.
Topics: Aged; Anterior Eye Segment; Blister; Combined Modality Therapy; Cross-Sectional Studies; Female; Gla | 2009 |
Noncontact in vivo scanning laser microscopy of filtering blebs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aqueous Humor; Blister; Combined Modality Therapy; Conju | 2009 |
Gemella species-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C.
Topics: Adult; Anti-Bacterial Agents; Blister; Conjunctiva; Drug Therapy, Combination; Endophthalmitis; Eye | 2009 |
Conjunctival and corneal findings in bleb-associated endophthalmitis: an in vivo confocal microscopy study.
Topics: Aged; Aged, 80 and over; Blister; Case-Control Studies; Conjunctivitis; Endophthalmitis; Female; Gla | 2011 |
Application of handheld cautery for reduction of symptomatic circumferential trabeculectomy blebs.
Topics: Aged; Ambulatory Surgical Procedures; Blister; Conjunctival Diseases; Electrocoagulation; Female; Gl | 2010 |
Early trabeculectomy bleb walls on anterior-segment optical coherence tomography.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Blister; Conjunctiva; Cross-Sectional Studies; Fe | 2010 |
Postoperative IOP is related to intrascleral bleb height in eyes with clinically flat blebs following deep sclerectomy with collagen implant and mitomycin.
Topics: Aged; Aged, 80 and over; Blister; Collagen; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressu | 2010 |
[Non-pentrating deep sclerectomy--between safety and efficacy].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antihypertensive Agents; Blister; Drug Therapy, Comb | 2010 |
Imaging of blebs after phacotrabeculectomy with Ologen collagen matrix implants.
Topics: Aged; Blister; Case-Control Studies; Collagen; Female; Humans; Intraocular Pressure; Male; Mitomycin | 2011 |
The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy.
Topics: Antimetabolites; Blister; Combined Modality Therapy; Conjunctiva; Female; Fluorouracil; Follow-Up St | 2011 |
Dramatic dysesthetic overhanging bleb.
Topics: Antibiotics, Antineoplastic; Blister; Combined Modality Therapy; Female; Glaucoma, Open-Angle; Human | 2011 |
Comparative study of encapsulated blebs following Ahmed glaucoma valve implantation and trabeculectomy with mitomycin-C.
Topics: Adult; Blister; Female; Glaucoma; Glaucoma Drainage Implants; Humans; Infant; Male; Middle Aged; Mit | 2012 |
Mucous membrane pemphigoid: nasal and laryngeal manifestations.
Topics: Adjuvants, Immunologic; Adult; Airway Obstruction; Blister; Female; Hand Dermatoses; Humans; Immunos | 2003 |
Delayed-onset, bleb-associated endophthalmitis caused by Lecythophora mutabilis.
Topics: Antifungal Agents; Blister; Combined Modality Therapy; Cryotherapy; Endophthalmitis; Eye Infections, | 2004 |
Bleb revision for hypotony maculopathy after trabeculectomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blister; Combined Modality Therapy; Female; Humans; Intr | 2004 |
[Surgical management of pathologic filtering blebs in pediatric glaucoma].
Topics: Adolescent; Anti-Bacterial Agents; Blister; Child; Endophthalmitis; Female; Glaucoma; Humans; Male; | 2004 |
Deep sclerectomy augmented with mitomycin C.
Topics: Aged; Antihypertensive Agents; Blister; Cicatrix; Conjunctiva; Epidemiologic Methods; Exudates and T | 2005 |
Filtering blebs imaging by optical coherence tomography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Child; Combined Modality Thera | 2005 |
Comparison of two clinical Bleb grading systems.
Topics: Blister; Diagnostic Techniques, Ophthalmological; Fluorouracil; Glaucoma; Humans; Mitomycin; Prospec | 2006 |
Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks.
Topics: Aged; Blister; Conjunctiva; Conjunctival Diseases; Female; Fluorouracil; Glaucoma; Humans; Intraocul | 2006 |
Determinants of bleb morphology in minimally invasive, clear-cornea micropenetrating glaucoma surgery with mitomycin C.
Topics: Adolescent; Adult; Aged; Antimetabolites; Blister; Child; Combined Modality Therapy; Conjunctiva; Co | 2006 |
Protection of the conjunctival flap from contact with mitomycin C during tunnel-trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Blister; Conjunctiva; Female; Follow-Up Studies; Humans; Intraocular | 2007 |
Surgical reduction of symptomatic, circumferential, filtering blebs.
Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Blister; Combined Modality Therapy; Conjunctiv | 2006 |
A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis).
Topics: Alkylating Agents; Animals; Antimetabolites; Blister; Conjunctiva; Connective Tissue; Connective Tis | 2006 |
Long-term results of amniotic membrane transplantation-assisted bleb revision for leaking blebs.
Topics: Adult; Aged; Alkylating Agents; Amnion; Blister; Combined Modality Therapy; Female; Humans; Intraocu | 2008 |
[Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps].
Topics: Adult; Aged; Antimetabolites; Blister; Combined Modality Therapy; Conjunctival Diseases; Female; Flu | 2001 |