mitomycin has been researched along with Benign Neoplasms, Brain in 35 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cytotoxic T lymphocytes (CTL) against autologous malignant brain tumor were generated in peripheral blood lymphoid cells (PBL) prepared from a patient with a malignant brain tumor by stimulation of the cultured PBL for 7 days with attenuated crossreactive malignant melanoma (MM2) cells pretreated with mitomycin C." | 3.69 | Induction of specific cytotoxic T lymphocytes against autologous brain tumor by crossreactive allo-tumor cell stimulation. ( Fujimoto, S; Kurisaka, M; Maeda, N; Mori, K; Saitoh, S, 1997) |
| "Mitomycin C has antitumor activity against squamous cell lung carcinoma when used alone or in combination with MVP." | 2.67 | A phase III trial of mitomycin C alone versus mitomycin C, vinblastine, and cisplatin for metastatic squamous cell lung carcinoma. ( Dalton, RJ; Etzell, PS; Foley, JF; Jett, JR; Kardinal, CG; Mailliard, JA; Maksymiuk, AW; Marschke, RF; Su, JQ; Veeder, MH, 1992) |
| "Esthesioneuroblastoma (olfactory neuroblastoma) is a rare neuroendocrine tumor that arises in the upper nasal cavity from the olfactory epithelium." | 2.40 | Chemotherapy for advanced esthesioneuroblastoma: the Mayo Clinic experience. ( Buckner, JC; Lewis, JE; McElroy, EA, 1998) |
| "Patients with brain metastases of triple negative breast cancer (TNBC) have a poor prognosis owing to the lack of targeted therapies, the aggressive nature of TNBC, and the presence of the blood-brain barrier (BBB) that blocks penetration of most drugs." | 1.51 | Multitargeted Nanoparticles Deliver Synergistic Drugs across the Blood-Brain Barrier to Brain Metastases of Triple Negative Breast Cancer Cells and Tumor-Associated Macrophages. ( Cai, P; He, C; Henderson, JT; Lip, H; Rauth, AM; Wang, Z; Wu, XY; Zhang, T, 2019) |
| "He then underwent excision of the brain metastases and consecutive radiation by X-knife." | 1.32 | [A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy]. ( Arai, K; Iwasaki, Y; Katayanagi, S; Matsumoto, H; Miyamoto, H; Takahashi, K; Yamaguchi, T, 2003) |
| "The chemotherapy for malignant brain tumors creates two major problems to be solved viz systemic toxicity and interference by the blood brain barrier." | 1.29 | [Pharmacodynamic study of mitomycin C mixed with fibrin glue for treatment of malignant brain tumors]. ( Kawasaki, H; Shimizu, T; Takakura, K; Umezawa, Y, 1994) |
| "Of the 15 patients who developed brain metastases after prior chemotherapy, 12 had received MAC at least once prior to the diagnosis of brain metastases, and in 5 patients, MAC was the first chemotherapy given after the diagnosis of brain metastases." | 1.28 | Intracerebral choriocarcinoma. ( Jones, WB; Lewis, JL; Wagner-Reiss, KM, 1990) |
| "Metronidazole, 1." | 1.27 | Feasibility study of combining metronidazole with chemotherapy. ( Bélanger, R; Crook, AF; Heringer, R; Hopkins, HS; Hugenholtz, H; Maroun, JA; Richard, MT; Stewart, DJ; Yan, RC; Young, V, 1983) |
| "Intracarotid CDDP infusion in combination with angiotensin II was performed in two patients with metastatic brain tumor, lung carcinoma (LC) and ovarian carcinoma (OC)." | 1.27 | [Intracarotid arterial infusion with CDDP in combination with angiotensin II]. ( Hino, N; Mitsuhata, N; Nishigaki, S; Suga, K; Tagusagawa, Y, 1984) |
| "Fifteen consenting patients with brain metastases recurrent after cranial irradiation were treated with intraarterial mitomycin-C, 15 mg/m2, administered in a total final volume of 100 ml 0." | 1.27 | Intraarterial mitomycin-C for recurrent brain metastases. ( Benoit, BG; Danjoux, C; Grahovac, Z; Hugenholtz, H; Maroun, JA; Richard, MT; Riding, MD; Russell, NA; Stewart, DJ, 1987) |
| "The disease appeared to be a diffuse encephalopathy frequently affecting the higher cortical functions." | 1.27 | Neurologic dysfunction in patients treated for small cell carcinoma of the lung: a clinical and radiological study. ( Chak, LY; Cox, RS; Kushlan, PD; Porzig, KJ; Sikic, BI; Wasserstein, P; Zatz, LM, 1986) |
| " Both dosage and releasing time can be adjusted." | 1.27 | [Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites]. ( Himuro, H; Inoue, N; Kaetsu, I; Kitamura, K; Kubo, O; Sakairi, M; Tajika, T; Tajika, Y; Tohyama, T; Yoshida, M, 1986) |
| "A case of brain metastasis in ovarian cancer is reported." | 1.27 | [Metastatic brain tumor after chemotherapy of ovarian cancer]. ( Chen, JT; Fujimoto, I; Fukuda, K; Hasumi, K; Masubuchi, K; Sakamoto, A; Yamauchi, K, 1987) |
| "Primary chemotherapy of brain metastases yielded responses in 27 of 52 patients (52%) treated with Cytoxan (cyclophosphamide) (C), 5-fluorouracil (F) and prednisone (P); 19 of 35 (54%) receiving CFP-methotrexate (M) and vincristine (V); 3 of 7 (43%) treated with MVP, and 1 of 6 (17%) receiving Cytoxan plus Adriamycin (doxorubicin) (CA)." | 1.27 | Chemotherapy induces regression of brain metastases in breast carcinoma. ( Lane, WW; Nemoto, T; Rosner, D, 1986) |
| "In those with metastatic brain tumors, the median survival time was 280 days, 1-year survival rate 43." | 1.27 | [Clinical application of a sustained release anticancer pellet]. ( Aoyama, I; Handa, H; Hashi, K; Kamijyo, Y; Mori, K; Oda, Y; Okumura, T; Tokuriki, Y; Yamashita, J, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (40.00) | 18.7374 |
| 1990's | 13 (37.14) | 18.2507 |
| 2000's | 5 (14.29) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kokoshka, JM | 1 |
| Ireland, CM | 1 |
| Barrows, LR | 1 |
| Iwasa, K | 1 |
| Moriyasu, M | 1 |
| Yamori, T | 1 |
| Turuo, T | 1 |
| Lee, DU | 1 |
| Wiegrebe, W | 1 |
| Zhang, RX | 1 |
| Li, J | 1 |
| Zhang, T | 2 |
| Amini, MA | 1 |
| He, C | 2 |
| Lu, B | 1 |
| Ahmed, T | 1 |
| Lip, H | 2 |
| Rauth, AM | 2 |
| Wu, XY | 2 |
| Cai, P | 1 |
| Wang, Z | 1 |
| Henderson, JT | 1 |
| Li, H | 1 |
| Liu, T | 1 |
| Chen, X | 2 |
| Xie, L | 1 |
| Chen, Y | 1 |
| Douglass, T | 1 |
| Jeffes, EW | 1 |
| Xu, Q | 1 |
| Williams, CC | 1 |
| Arpajirakul, N | 1 |
| Delgado, C | 1 |
| Kleinman, M | 1 |
| Sanchez, R | 1 |
| Dan, Q | 1 |
| Kim, RC | 1 |
| Wepsic, HT | 1 |
| Jadus, MR | 1 |
| Yuan, S | 1 |
| Wang, Y | 1 |
| Jiang, S | 1 |
| Yang, Y | 1 |
| Song, Y | 1 |
| Tu, C | 1 |
| Katayanagi, S | 1 |
| Arai, K | 1 |
| Iwasaki, Y | 1 |
| Takahashi, K | 1 |
| Yamaguchi, T | 1 |
| Matsumoto, H | 1 |
| Miyamoto, H | 1 |
| Giroux, MF | 1 |
| Baum, RA | 1 |
| Soulen, MC | 1 |
| Stewart, DJ | 3 |
| Maroun, JA | 2 |
| Young, V | 1 |
| Crook, AF | 1 |
| Hopkins, HS | 1 |
| Yan, RC | 1 |
| Richard, MT | 2 |
| Hugenholtz, H | 2 |
| Bélanger, R | 1 |
| Heringer, R | 1 |
| Mitsuhata, N | 1 |
| Hino, N | 1 |
| Tagusagawa, Y | 1 |
| Suga, K | 1 |
| Nishigaki, S | 1 |
| Tajima, H | 1 |
| Matsuki, N | 1 |
| Takeda, T | 1 |
| Horichi, H | 1 |
| Kumaki, T | 1 |
| Shima, K | 1 |
| Kawasaki, H | 1 |
| Shimizu, T | 1 |
| Takakura, K | 1 |
| Umezawa, Y | 1 |
| Halperin, EC | 1 |
| Herndon, J | 1 |
| Schold, SC | 1 |
| Brown, M | 1 |
| Vick, N | 1 |
| Cairncross, JG | 1 |
| Macdonald, DR | 1 |
| Gaspar, L | 1 |
| Fischer, B | 1 |
| Dropcho, E | 1 |
| Rosenfeld, S | 1 |
| Morowitz, R | 1 |
| Piepmeier, J | 1 |
| Hait, W | 1 |
| Byrne, T | 1 |
| Salter, M | 1 |
| Imperato, J | 1 |
| Khandekar, J | 1 |
| Paleologos, N | 1 |
| Burger, P | 1 |
| Bentel, GC | 1 |
| Friedman, A | 1 |
| Sekine, I | 1 |
| Sasaki, Y | 1 |
| Fujii, H | 1 |
| Ohtsu, T | 1 |
| Wakita, H | 1 |
| Igarashi, T | 1 |
| Itoh, K | 1 |
| Abe, K | 1 |
| Furuse, K | 1 |
| Kamimori, T | 1 |
| Kawahara, M | 1 |
| Kodama, N | 1 |
| Ogawara, M | 1 |
| Atagi, S | 1 |
| Naka, N | 1 |
| Akira, M | 1 |
| Kubota, K | 1 |
| Dahrouge, S | 1 |
| Agboola, O | 1 |
| Girard, A | 1 |
| Saitoh, S | 1 |
| Kurisaka, M | 1 |
| Mori, K | 3 |
| Maeda, N | 1 |
| Fujimoto, S | 1 |
| McElroy, EA | 1 |
| Buckner, JC | 1 |
| Lewis, JE | 1 |
| Veeder, MH | 1 |
| Jett, JR | 1 |
| Su, JQ | 1 |
| Mailliard, JA | 1 |
| Foley, JF | 1 |
| Dalton, RJ | 1 |
| Etzell, PS | 1 |
| Marschke, RF | 1 |
| Kardinal, CG | 1 |
| Maksymiuk, AW | 1 |
| Nitta, T | 1 |
| Nikkhah, G | 1 |
| Tonn, JC | 1 |
| Hoffmann, O | 1 |
| Kraemer, HP | 1 |
| Darling, JL | 1 |
| Schachenmayr, W | 1 |
| Schönmayr, R | 1 |
| Jones, WB | 1 |
| Wagner-Reiss, KM | 1 |
| Lewis, JL | 1 |
| Oda, Y | 2 |
| Kamijo, Y | 1 |
| Kang, Y | 1 |
| Okumura, T | 2 |
| Tokuriki, Y | 2 |
| Handa, H | 2 |
| Hashi, K | 2 |
| Kawakami, K | 1 |
| Kawamoto, K | 1 |
| Oka, N | 1 |
| Kawamura, Y | 1 |
| Matsumura, H | 1 |
| Ito, T | 1 |
| Ohyama, A | 1 |
| Grahovac, Z | 1 |
| Russell, NA | 1 |
| Benoit, BG | 1 |
| Riding, MD | 1 |
| Danjoux, C | 1 |
| Mira, JG | 1 |
| Taylor, SL | 1 |
| Stephens, RL | 1 |
| Chen, T | 1 |
| Petursson, SR | 1 |
| Chak, LY | 1 |
| Zatz, LM | 1 |
| Wasserstein, P | 1 |
| Cox, RS | 1 |
| Kushlan, PD | 1 |
| Porzig, KJ | 1 |
| Sikic, BI | 1 |
| Kubo, O | 1 |
| Himuro, H | 1 |
| Inoue, N | 1 |
| Tajika, Y | 1 |
| Tajika, T | 1 |
| Tohyama, T | 1 |
| Sakairi, M | 1 |
| Yoshida, M | 1 |
| Kaetsu, I | 1 |
| Kitamura, K | 1 |
| Nozue, AT | 1 |
| Fukuda, K | 1 |
| Chen, JT | 1 |
| Fujimoto, I | 1 |
| Yamauchi, K | 1 |
| Hasumi, K | 1 |
| Masubuchi, K | 1 |
| Sakamoto, A | 1 |
| Rosner, D | 1 |
| Nemoto, T | 1 |
| Lane, WW | 1 |
| Ito, H | 1 |
| Hasegawa, T | 1 |
| Shoin, K | 1 |
| Hwang, WZ | 1 |
| Hayashi, M | 1 |
| Yamamoto, S | 1 |
| Miyazaki, I | 1 |
| Kamijyo, Y | 1 |
| Yamashita, J | 1 |
| Aoyama, I | 1 |
3 reviews available for mitomycin and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Importance of integrating nanotechnology with pharmacology and physiology for innovative drug delivery and therapy - an illustration with firsthand examples.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Doxorubicin; Drug Carriers; Humans; Lung Neoplasms; | 2018 |
Chemotherapy for advanced esthesioneuroblastoma: the Mayo Clinic experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; | 1998 |
[A history and prospect of adoptive immunotherapy against malignant glioma--past, now and future].
Topics: Brain Neoplasms; Glioma; Humans; Immunotherapy, Adoptive; Immunotoxins; Interleukin-2; Killer Cells, | 1992 |
3 trials available for mitomycin and Benign Neoplasms, Brain
| Article | Year |
|---|---|
A phase III randomized prospective trial of external beam radiotherapy, mitomycin C, carmustine, and 6-mercaptopurine for the treatment of adults with anaplastic glioma of the brain. CNS Cancer Consortium.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M | 1996 |
Cranial radiation and concomitant cisplatin and mitomycin-C plus resistance modulators for malignant gliomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta Carotene; Brain Neoplasms; Cisplat | 1997 |
A phase III trial of mitomycin C alone versus mitomycin C, vinblastine, and cisplatin for metastatic squamous cell lung carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car | 1992 |
29 other studies available for mitomycin and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Forma | 1996 |
In vitro cytotoxicity of the protoberberine-type alkaloids.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast | 2001 |
Multitargeted Nanoparticles Deliver Synergistic Drugs across the Blood-Brain Barrier to Brain Metastases of Triple Negative Breast Cancer Cells and Tumor-Associated Macrophages.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Disease Progression; Dox | 2019 |
A rare case of primary congenital glaucoma in combination with neurofibromatosis 1: a case report.
Topics: Alkylating Agents; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Hydrophthalmos; Infan | 2015 |
Living T9 glioma cells expressing membrane macrophage colony-stimulating factor produce immediate tumor destruction by polymorphonuclear leukocytes and macrophages via a "paraptosis"-induced pathway that promotes systemic immunity against intracranial T9
Topics: Animals; Antibodies; Brain Neoplasms; Cell Death; Chemokines, CXC; Chemotactic Factors; Female; Free | 2002 |
[Study on chemosensitivity assay in vitro in the peripheral blood lymphocyte and the tumor cells].
Topics: Antineoplastic Agents; Brain Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Glioma; Human | 2000 |
[A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy].
Topics: Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Brain Neoplasm | 2003 |
Chemoembolization of liver metastasis from breast carcinoma.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcin | 2004 |
Feasibility study of combining metronidazole with chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Sq | 1983 |
[Intracarotid arterial infusion with CDDP in combination with angiotensin II].
Topics: Adenocarcinoma, Papillary; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Bra | 1984 |
[A case of cutaneous and brain metastasis of gastric carcinoma, treated effectively by chemotherapy with CDDP, MMC, etoposide and 5'-DFUR].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Ne | 1994 |
[Pharmacodynamic study of mitomycin C mixed with fibrin glue for treatment of malignant brain tumors].
Topics: Animals; Brain Neoplasms; Delayed-Action Preparations; Fibrin Tissue Adhesive; Male; Mice; Mice, Inb | 1994 |
Recurrent breast cancer treated successfully with mitomycin-C and vinblastine after failure of both doxorubicin-containing regimen and paclitaxel--a case report.
Topics: Adenocarcinoma, Scirrhous; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Br | 1996 |
A pilot study of concurrent whole-brain radiotherapy and chemotherapy combined with cisplatin, vindesine and mitomycin in non-small-cell lung cancer with brain metastasis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-C | 1997 |
Induction of specific cytotoxic T lymphocytes against autologous brain tumor by crossreactive allo-tumor cell stimulation.
Topics: Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Autoant | 1997 |
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Color | 1992 |
Intracerebral choriocarcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Cisplatin; | 1990 |
[Evaluation of the sustained release of anticancer agents from silicone pellets].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Cytarabine; Delayed-Acti | 1985 |
[Flow cytometric studies of brain tumors--5: New sensitivity test of antineoplastic agents for brain tumors and its clinical application].
Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Cell Cycle; Cell Survival; Colony-Formin | 1986 |
Intraarterial mitomycin-C for recurrent brain metastases.
Topics: Adolescent; Adult; Animals; Brain Neoplasms; Carotid Artery, Internal; Humans; Infusions, Intra-Arte | 1987 |
Simultaneous chemotherapy-radiotherapy with prophylactic cranial irradiation for inoperable adeno and large cell lung carcinoma: a Southwest Oncology Group Study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcin | 1988 |
Adenoid cystic carcinoma of the esophagus. Complete response to combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Adenoid Cystic; Cisplati | 1986 |
Neurologic dysfunction in patients treated for small cell carcinoma of the lung: a clinical and radiological study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Diseases; Brain Neoplasms; | 1986 |
[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites].
Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Implants; Dysge | 1986 |
Effects of mitomycin C in the central nervous system in newborn mice with special reference to neutral crest cells.
Topics: Animals; Animals, Newborn; Brain; Brain Neoplasms; Mice; Mitomycin; Mitomycins; Neural Crest | 1986 |
[Metastatic brain tumor after chemotherapy of ovarian cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cisplatin; Cyclop | 1987 |
Chemotherapy induces regression of brain metastases in breast carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autopsy; Brain Neoplasms; Breast Neopla | 1986 |
[Necrotomy of brain stem glioma and local administration of anticancer agents].
Topics: Administration, Topical; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; B | 1985 |
[Clinical application of a sustained release anticancer pellet].
Topics: Antineoplastic Agents; Brain Neoplasms; Delayed-Action Preparations; Drug Administration Schedule; F | 1985 |