Page last updated: 2024-11-06

mitomycin and Autoimmune Disease

mitomycin has been researched along with Autoimmune Disease in 7 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"We study the efficacy of treating ocular cicatricial pemphigoid (OCP) with subconjuctival mitomycin C (MMC)."1.31[Subconjunctival mitomycin C for the treatment of ocular cicatricial pemphigoid]. ( Celis Sánchez, J; García Largacha, M; González del Valle, F; López Ferrando, N; Ortiz de la Torre, MJ, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Terness, P2
Oelert, T1
Ehser, S2
Chuang, JJ2
Lahdou, I1
Kleist, C2
Velten, F1
Hämmerling, GJ1
Arnold, B1
Opelz, G2
Simon, H1
Sandra-Petrescu, F1
Mohr, E1
Jiga, L1
Greil, J1
Abo-Elwafa, HA1
Attia, FM1
Sharaf, AE1
Celis Sánchez, J1
López Ferrando, N1
García Largacha, M1
González del Valle, F1
Ortiz de la Torre, MJ1
Kallio, M1
Lähdetie, J1
Hirsch, RL1
Katagiri, T1
Tomiyama, H1
Kyuwa, S1
Kano, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single-arm Phase-I Trial for the Determination of Safety and Feasibility of the Intravenous Administration of Mitomycin C-treated Donor Peripheral Blood Mononuclear Cells (MICs) for Individualized Immunosuppression in Living Donor Kidney Transplant Reci[NCT02560220]Phase 114 participants (Actual)Interventional2015-08-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for mitomycin and Autoimmune Disease

ArticleYear
Mitomycin C-treated dendritic cells inactivate autoreactive T cells: toward the development of a tolerogenic vaccine in autoimmune diseases.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Nov-25, Volume: 105, Issue:47

    Topics: Animals; Autoimmune Diseases; Dendritic Cells; Encephalomyelitis, Autoimmune, Experimental; G1 Phase

2008
Mitomycin C-treated antigen-presenting cells as a tool for control of allograft rejection and autoimmunity: from bench to bedside.
    Human immunology, 2009, Volume: 70, Issue:7

    Topics: Adoptive Transfer; Animals; Antigen-Presenting Cells; Apoptosis; Autoimmune Diseases; Autoimmunity;

2009
The prognostic value of p53 mutation in pediatric marrow hypoplasia.
    Diagnostic pathology, 2011, Jun-30, Volume: 6

    Topics: Adolescent; Anemia, Aplastic; Autoimmune Diseases; Bone Marrow Cells; Child; Child, Preschool; Chrom

2011
[Subconjunctival mitomycin C for the treatment of ocular cicatricial pemphigoid].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:9

    Topics: Aged; Aged, 80 and over; Autoimmune Diseases; Disease Progression; Drug Evaluation; Drug Therapy, Co

2002
Analysis of micronuclei induced in mouse early spermatids by mitomycin C, vinblastine sulfate or etoposide using fluorescence in situ hybridization.
    Mutagenesis, 1993, Volume: 8, Issue:6

    Topics: Animals; Autoimmune Diseases; Centromere; CREST Syndrome; DNA Probes; Etoposide; Fluorescent Antibod

1993
Defective autologous mixed lymphocyte reactivity in multiple sclerosis.
    Clinical and experimental immunology, 1986, Volume: 64, Issue:1

    Topics: Autoimmune Diseases; Humans; In Vitro Techniques; Lymphocyte Culture Test, Mixed; Mitomycin; Mitomyc

1986
Interleukin-2 responses of MRL/lpr mouse splenocytes and lymph node cells induced by TPA and A23187.
    International archives of allergy and applied immunology, 1987, Volume: 83, Issue:2

    Topics: Animals; Autoimmune Diseases; Calcimycin; Calcium; Calcium Channel Blockers; Dactinomycin; Egtazic A

1987