Page last updated: 2024-11-06

mitomycin and Atresia, Choanal

mitomycin has been researched along with Atresia, Choanal in 20 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"Management of bilateral congenital choanal atresia is better by endoscopic transnasal approach with application of mitomycin-c."2.78Management of bilateral congenital choanal atresia. ( Hadi, HI; Homaira, R; Sattar, MA; Sultana, T, 2013)
"Bilateral choanal atresia requires prompt surgical intervention."2.72Stenting versus stentless repair for bilateral choanal atresia: A systematic review of the literature. ( Gundle, L; Hendry, J; Ojha, S; Rosen, H, 2021)
"Fifteen patients; choanal atresia in 5 patients, airway stenosis in 8 patients, hypopharyngeal stenosis in 1 patient, and esophageal stenosis in 1 patient."2.70The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe? ( Healy, GB; Jones, DT; Kenna, MA; McGill, TJ; Nuss, RC; Rahbar, R; Roberson, DW, 2002)
"Mitomycin C has been used for the past 16 years to inhibit pediatric airway fibroblast proliferation."2.50The use of mitomycin C in pediatric airway surgery: does it work? ( Bent, JP; Gangar, M, 2014)
"Choanal atresia is postulated to be secondary to an abnormality of the rupture of the buccopharyngeal membrane during the embryological period."2.41Unilateral choanal atresia in identical twins: case report and literature review. ( Carvalho, DS; Chia, SH; Jaffe, DM; Pransky, SM, 2002)
"High-concentration MMC was considered safe in the pediatric and adult populations."1.72Safety profile and efficacy of high-dose topical mitomycin-C for choanal atresia repair: A prospective cohort study. ( Alammar, A; Aldriweesh, B; Aljasser, A; Alshareef, W; Alsini, A, 2022)
"Unilateral choanal atresia surgery should be delayed after age 6 months and/or weight >5 kg when possible."1.51Prognostic Factors and Management of Patients with Choanal Atresia. ( Moreddu, E; Nicollas, R; Rossi, ME; Triglia, JM, 2019)
"Patients were monitored for re-stenosis and revisions carried out as necessary, with a mean follow-up of 11."1.38Transnasal endoscopic repair of choanal atresia in a tertiary care centre: a review of outcomes. ( Al-Omari, B; Glynn, F; Hone, S; Russell, J; Uzomefuna, V, 2012)
"Mitomycin was used according to the senior surgeon's preference, and certainly not in a randomized fashion."1.36The use of adjunctive topical mitomycin in endoscopic congenital choanal atresia repair. ( Arbag, H; Azimov, A; Bozkurt, MK; Keles, B; Ozturk, K, 2010)
"Mitomycin-C application has being shown useful adjunct to surgical technique in managing nasopharyngeal stenosis for surgeons."1.35Velopharyngeal stenosis, a late complication of radiotherapy. ( Kumar, SS; Lee, SC; Singh, A; Singh, S; Tang, IP, 2009)
"Since the first description of choanal atresia (CA) in 1755, multiple surgical techniques have been proposed to repair the malformation."1.32Revision choanal atresia repair. ( Brooks, DB; Mair, EA; McLeod, IK, 2003)
"Mitomycin is an effective and reliable treatment for improving the surgical outcome for choanal atresia repair."1.31Surgical management of choanal atresia: improved outcome using mitomycin. ( Holland, BW; McGuirt, WF, 2001)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (45.00)29.6817
2010's7 (35.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Gundle, L1
Ojha, S1
Hendry, J1
Rosen, H1
Aldriweesh, B1
Alshareef, W1
Alsini, A1
Aljasser, A1
Alammar, A1
De Vincentiis, GC1
Panatta, ML1
De Corso, E1
Marini, G1
Bianchi, A1
Giuliani, M1
Sitzia, E1
Tucci, FM1
Attya, H1
Callaby, M1
Thevasagayam, R1
Moreddu, E1
Rossi, ME1
Nicollas, R1
Triglia, JM1
Sattar, MA1
Hadi, HI1
Homaira, R1
Sultana, T1
Carter, JM1
Lawlor, C1
Guarisco, JL1
Gangar, M1
Bent, JP2
Lee, SC1
Tang, IP1
Singh, A1
Kumar, SS1
Singh, S1
Bozkurt, MK1
Keles, B1
Azimov, A1
Ozturk, K1
Arbag, H1
Uzomefuna, V1
Glynn, F1
Al-Omari, B1
Hone, S1
Russell, J1
Newman, JR1
Harmon, P1
Shirley, WP1
Hill, JS1
Woolley, AL1
Wiatrak, BJ1
Rombaux, P1
de Toeuf, C1
Hamoir, M1
Eloy, P1
Bertrand, B1
Veykemans, F1
McLeod, IK1
Brooks, DB1
Mair, EA1
Todd, DW1
Al-Ammar, AY1
Holland, BW1
McGuirt, WF1
Chia, SH1
Carvalho, DS1
Jaffe, DM1
Pransky, SM1
Prasad, M1
Ward, RF1
April, MM1
Froehlich, P1
Rahbar, R1
Jones, DT1
Nuss, RC1
Roberson, DW1
Kenna, MA1
McGill, TJ1
Healy, GB1

Reviews

4 reviews available for mitomycin and Atresia, Choanal

ArticleYear
Stenting versus stentless repair for bilateral choanal atresia: A systematic review of the literature.
    International journal of pediatric otorhinolaryngology, 2021, Volume: 151

    Topics: Choanal Atresia; Endoscopy; Humans; Mitomycin; Stents; Surgical Flaps; Treatment Outcome

2021
Choanal atresia surgery: outcomes in 42 patients over 20 years and a review of the literature.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021, Volume: 278, Issue:7

    Topics: Choanal Atresia; Endoscopy; Humans; Mitomycin; Reoperation; Stents; Treatment Outcome

2021
The use of mitomycin C in pediatric airway surgery: does it work?
    Current opinion in otolaryngology & head and neck surgery, 2014, Volume: 22, Issue:6

    Topics: Alkylating Agents; Choanal Atresia; Combined Modality Therapy; Fibroblasts; Humans; Mitomycin; Trach

2014
Unilateral choanal atresia in identical twins: case report and literature review.
    International journal of pediatric otorhinolaryngology, 2002, Feb-25, Volume: 62, Issue:3

    Topics: Alkylating Agents; Child; Choanal Atresia; Diseases in Twins; Endoscopy; Humans; Male; Mitomycin; Ot

2002

Trials

3 trials available for mitomycin and Atresia, Choanal

ArticleYear
Management of bilateral congenital choanal atresia.
    Mymensingh medical journal : MMJ, 2013, Volume: 22, Issue:1

    Topics: Choanal Atresia; Endoscopy; Female; Follow-Up Studies; Granulation Tissue; Humans; Infant, Newborn;

2013
Effect of use of mitomycin C on the outcome of Choanal atresia repair.
    Saudi medical journal, 2007, Volume: 28, Issue:10

    Topics: Adolescent; Antibiotics, Antineoplastic; Child; Child, Preschool; Choanal Atresia; Endoscopy; Female

2007
The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe?
    Archives of otolaryngology--head & neck surgery, 2002, Volume: 128, Issue:4

    Topics: Administration, Topical; Aminoglycosides; Anti-Bacterial Agents; Child; Child, Preschool; Choanal At

2002

Other Studies

13 other studies available for mitomycin and Atresia, Choanal

ArticleYear
Safety profile and efficacy of high-dose topical mitomycin-C for choanal atresia repair: A prospective cohort study.
    International journal of pediatric otorhinolaryngology, 2022, Volume: 159

    Topics: Adult; Child; Child, Preschool; Choanal Atresia; Female; Humans; Mitomycin; Prospective Studies; Reo

2022
Endoscopic treatment of choanal atresia and use of balloon dilation: our experience.
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2020, Volume: 40, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Child; Child, Preschool; Choanal Atresia; Endoscopy; Female; Follow-

2020
Prognostic Factors and Management of Patients with Choanal Atresia.
    The Journal of pediatrics, 2019, Volume: 204

    Topics: Adolescent; Alkylating Agents; Child; Child, Preschool; Choanal Atresia; Endoscopy; Female; Humans;

2019
The efficacy of mitomycin and stenting in choanal atresia repair: a 20 year experience.
    International journal of pediatric otorhinolaryngology, 2014, Volume: 78, Issue:2

    Topics: Administration, Topical; Adolescent; Alkylating Agents; Child; Choanal Atresia; Endoscopy; Female; H

2014
Velopharyngeal stenosis, a late complication of radiotherapy.
    Auris, nasus, larynx, 2009, Volume: 36, Issue:6

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Choanal Atresia; Combi

2009
The use of adjunctive topical mitomycin in endoscopic congenital choanal atresia repair.
    International journal of pediatric otorhinolaryngology, 2010, Volume: 74, Issue:7

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Child; Child, Preschool; Choanal Atresia; Cons

2010
Transnasal endoscopic repair of choanal atresia in a tertiary care centre: a review of outcomes.
    International journal of pediatric otorhinolaryngology, 2012, Volume: 76, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Choanal Atresia; Constriction, Pathologic; Endoscopy; Female; H

2012
Operative management of choanal atresia: a 15-year experience.
    JAMA otolaryngology-- head & neck surgery, 2013, Volume: 139, Issue:1

    Topics: Adolescent; Alkylating Agents; Child; Child, Preschool; Choanal Atresia; Endoscopy; Female; Humans;

2013
Transnasal repair of unilateral choanal atresia.
    Rhinology, 2003, Volume: 41, Issue:1

    Topics: Child, Preschool; Choanal Atresia; Debridement; Endoscopy; Female; Humans; Infant; Male; Mitomycin;

2003
Revision choanal atresia repair.
    International journal of pediatric otorhinolaryngology, 2003, Volume: 67, Issue:5

    Topics: Administration, Topical; Adolescent; Child, Preschool; Choanal Atresia; Debridement; Endoscopy; Fema

2003
Choanal atresia: endoscopic repair in three recent cases and a review of the literature.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2006, Volume: 59, Issue:3

    Topics: Choanal Atresia; Endoscopy; Female; Humans; Infant; Infant, Newborn; Male; Mitomycin; Reoperation; R

2006
Surgical management of choanal atresia: improved outcome using mitomycin.
    Archives of otolaryngology--head & neck surgery, 2001, Volume: 127, Issue:11

    Topics: Administration, Topical; Alkylating Agents; Child; Child, Preschool; Choanal Atresia; Female; Granul

2001
Topical mitomycin as an adjunct to choanal atresia repair.
    Archives of otolaryngology--head & neck surgery, 2002, Volume: 128, Issue:4

    Topics: Administration, Topical; Aminoglycosides; Anti-Bacterial Agents; Choanal Atresia; Female; Humans; In

2002