mitomycin has been researched along with Astrocytoma in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three metastatic variants, BL6 (high metastasis), F1 (nonmalignant) and F10 (intermediate malignancy) of the B16 murine melanoma, and a pulmonary metastatic line BL6-ML8 of the BL6 primary tumour have been examined for spontaneous sister chromatid exchange (SCE)." | 1.27 | Spontaneous sister chromatid exchange in metastatic variants of the murine B16 melanoma and human astrocytomas in culture. ( Hunt, G; Lakshmi, MS; Sherbet, GV, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manome, Y | 1 |
| Datta, R | 1 |
| Fine, HA | 1 |
| Lakshmi, MS | 1 |
| Hunt, G | 1 |
| Sherbet, GV | 1 |
2 other studies available for mitomycin and Astrocytoma
| Article | Year |
|---|---|
Early response gene induction following DNA damage in astrocytoma cell lines.
Topics: Astrocytoma; Cell Death; DNA Damage; Gene Expression; Genes, fos; Genes, jun; Hematopoietic Stem Cel | 1993 |
Spontaneous sister chromatid exchange in metastatic variants of the murine B16 melanoma and human astrocytomas in culture.
Topics: Animals; Astrocytoma; Ethyl Methanesulfonate; Humans; Melanoma, Experimental; Mice; Mitomycin; Mitom | 1988 |