mitomycin has been researched along with Arthritis, Rheumatoid in 6 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitomycin C (MMC) has previously been demonstrated to inhibit fibroblast proliferation and to induce fibroblast apoptosis." | 5.42 | Mitomycin C induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via a mitochondrial-mediated pathway. ( Cao, X; Ge, D; Kong, D; Su, C; Yan, C; Zhang, X; Zhang, Y, 2015) |
| "Mitomycin C (MMC) has previously been demonstrated to inhibit fibroblast proliferation and to induce fibroblast apoptosis." | 1.42 | Mitomycin C induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via a mitochondrial-mediated pathway. ( Cao, X; Ge, D; Kong, D; Su, C; Yan, C; Zhang, X; Zhang, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Svrcina, H | 1 |
| Greer, A | 1 |
| Baker, S | 1 |
| Smith, M | 1 |
| Martinez, P | 1 |
| Granger, N | 1 |
| Thomas, N | 1 |
| Miller, J | 1 |
| Steinke, E | 1 |
| Davitt, K | 1 |
| Sloane, E | 1 |
| Nugent, L | 1 |
| Sabo, R | 1 |
| Williams, C | 1 |
| Lipton, MA | 1 |
| Jones, D | 1 |
| Yan, C | 1 |
| Kong, D | 1 |
| Ge, D | 1 |
| Zhang, Y | 1 |
| Zhang, X | 1 |
| Su, C | 1 |
| Cao, X | 1 |
| Panush, RS | 1 |
| Golds, EE | 1 |
| Cooke, TD | 1 |
| Poole, AR | 1 |
| Sakai, M | 1 |
| Eguchi, K | 1 |
| Terada, K | 1 |
| Nakashima, M | 1 |
| Yamashita, I | 1 |
| Ida, H | 1 |
| Kawabe, Y | 1 |
| Aoyagi, T | 1 |
| Takino, H | 1 |
| Nakamura, T | 1 |
| Thomas, R | 1 |
| McIlraith, M | 1 |
| Davis, LS | 1 |
| Lipsky, PE | 1 |
6 other studies available for mitomycin and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Death effects of reveromycin A in normal and disease-associated cells of the joint.
Topics: Animals; Apoptosis; Arthritis, Rheumatoid; Cell Line; Fibroblasts; Humans; Hydrogen-Ion Concentratio | 2018 |
Mitomycin C induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via a mitochondrial-mediated pathway.
Topics: Apoptosis; Arthritis, Rheumatoid; Cell Count; Cell Line; Cell Proliferation; Cell Survival; Fibrobla | 2015 |
A new, simplified assay for suppressor cell function.
Topics: Arthritis, Rheumatoid; Cell Line; Cell Survival; Cells, Cultured; Concanavalin A; Humans; Immunologi | 1982 |
Immune regulation of collagenase secretion in rheumatoid and osteoarthritic synovial cell cultures.
Topics: Antigens; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Humans; Immunity; Microbial Collage | 1983 |
Infection of human synovial cells by human T cell lymphotropic virus type I. Proliferation and granulocyte/macrophage colony-stimulating factor production by synovial cells.
Topics: Arthritis, Rheumatoid; Cell Division; Cell Line; Cells, Cultured; Culture Media, Conditioned; DNA, V | 1993 |
Rheumatoid synovium is enriched in CD45RBdim mature memory T cells that are potent helpers for B cell differentiation.
Topics: Adult; Aged; Arthritis, Rheumatoid; B-Lymphocytes; Cell Differentiation; Cells, Cultured; Female; Hu | 1992 |