Page last updated: 2024-11-06

mitomycin and Appendiceal Cancer

mitomycin has been researched along with Appendiceal Cancer in 64 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"This study evaluated health-related quality of life (HRQOL) using patient-reported outcomes in subjects with mucinous appendiceal neoplasms who underwent cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as part of a randomized trial comparing mitomycin with oxaliplatin."9.34Health-Related Quality of Life After Cytoreductive Surgery/HIPEC for Mucinous Appendiceal Cancer: Results of a Multicenter Randomized Trial Comparing Oxaliplatin and Mitomycin. ( Bartlett, DL; Levine, EA; Mansfield, P; McQuellon, R; Moaven, O; Russell, G; Shen, P; Stewart, JH; Votanopoulos, KI, 2020)
"The patients included were 145 who had colorectal or appendiceal carcinomatosis resected using cytoreductive surgery prior to treatment with hyperthermic intraperitoneal chemotherapy with mitomycin C as part of a multidrug regimen."7.77Changes induced by surgical and clinical factors in the pharmacology of intraperitoneal mitomycin C in 145 patients with peritoneal carcinomatosis. ( Chang, D; Mahteme, H; Stuart, OA; Sugarbaker, PH; Van der Speeten, K, 2011)
"Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix."7.68Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990)
"Neutropenia is a frequent complication associated with MMC-HIPEC."5.35Incidence, risk factors, and impact of severe neutropenia after hyperthermic intraperitoneal mitomycin C. ( Armstrong, TS; Eng, C; Gonzalez-Moreno, S; Katz, MH; Lambert, DH; Lambert, LA; Lee, JJ; Liu, S; Mansfield, PF; Tansey, P; Tortorice, ML; Wolff, RA, 2009)
"This study evaluated health-related quality of life (HRQOL) using patient-reported outcomes in subjects with mucinous appendiceal neoplasms who underwent cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as part of a randomized trial comparing mitomycin with oxaliplatin."5.34Health-Related Quality of Life After Cytoreductive Surgery/HIPEC for Mucinous Appendiceal Cancer: Results of a Multicenter Randomized Trial Comparing Oxaliplatin and Mitomycin. ( Bartlett, DL; Levine, EA; Mansfield, P; McQuellon, R; Moaven, O; Russell, G; Shen, P; Stewart, JH; Votanopoulos, KI, 2020)
"Although peritoneal carcinomatosis (PC) from colorectal and appendiceal tumors is consistent with metastatic disease, complete cytoreduction with hyperthermic intraperitoneal chemotherapy (HIPEC) using mitomycin C (MMC) can improve survival."3.79A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C. ( Ihemelandu, C; Levine, EA; Russell, G; Shen, P; Stewart, J; Votanopoulos, K, 2013)
"The patients included were 145 who had colorectal or appendiceal carcinomatosis resected using cytoreductive surgery prior to treatment with hyperthermic intraperitoneal chemotherapy with mitomycin C as part of a multidrug regimen."3.77Changes induced by surgical and clinical factors in the pharmacology of intraperitoneal mitomycin C in 145 patients with peritoneal carcinomatosis. ( Chang, D; Mahteme, H; Stuart, OA; Sugarbaker, PH; Van der Speeten, K, 2011)
"Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix."3.68Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990)
"Appendiceal cancer is a rare disease that has proven difficult to study in prospective trials."2.87A Multicenter Randomized Trial to Evaluate Hematologic Toxicities after Hyperthermic Intraperitoneal Chemotherapy with Oxaliplatin or Mitomycin in Patients with Appendiceal Tumors. ( Bartlett, D; Fenstermaker, J; Levine, EA; Mansfield, P; Russell, G; Shen, P; Stewart, JH; Votanopoulos, KI, 2018)
"The median (range) peritoneal carcinomatosis index was 13 (3-20) requiring a median operative time of 6."2.78A phase I trial of thermal sensitization using induced oxidative stress in the context of HIPEC. ( Harrison, LE; Razavi, R; Tiesi, G; Wang, CC, 2013)
"There were 51 patients with colorectal cancer and 130 patients with appendiceal cancer."2.68Prognostic features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intraperitoneal chemotherapy. ( Jablonski, KA; Sugarbaker, PH, 1995)
"Mucinous appendiceal neoplasms (MANs) are rare tumours and the primary cause of pseudomyxoma peritonei."2.66Mucinous appendiceal neoplasms with or without pseudomyxoma peritonei: a review. ( Alshahrani, MS; Lansom, J; Morris, DL; Soucisse, ML, 2020)
"Management of peritoneal disease from appendiceal neoplasms has historically been with debulking surgery."2.61Outcomes from cytoreduction and hyperthermic intraperitoneal chemotherapy for appendiceal epithelial neoplasms. ( Craig Lynch, A; Heriot, A; Michael, M; Narasimhan, V; Pham, T; Ramsay, R; Tie, J; Warrier, S, 2019)
"Mitomycin-C (MMC) was used in 20% and oxaliplatin in 10%."1.56Toxicity profile of chemotherapy agents used in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies. ( Ashwin, KR; Kumar C, R; Rauthan, A; Somashekhar, SP; Yethadka, R; Zaveri, S, 2020)
" The study is to analyze the incidence of perioperative serious adverse events (SAEs) of CRS + HIPEC to treat PMP patients, and identify the risk factors, for guiding the prevention of SAEs."1.56Perioperative safety after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei from appendiceal origin: Experience on 254 patients from a single center. ( Chen, LF; Ji, ZH; Li, XB; Li, Y; Lin, YL; Ma, R; Yan, FC; Yang, ZR; Zhang, J, 2020)
"Pseudomyxoma peritonei is rare, almost always of appendiceal origin, and presents in various ways relevant to abdominal surgeons."1.56Mode of Presentation in 1070 Patients With Perforated Epithelial Appendiceal Tumors, Predominantly with Pseudomyxoma Peritonei. ( Cecil, TD; Chandrakumaran, K; Dayal, S; Mohamed, F; Moran, BJ; Shariff, US, 2020)
"No recurrent inguinal hernias were recorded and no patients required an inguinal incision at a later time to resect progressive disease within the inguinal canal."1.46Management of an inguinal hernia in patients with pseudomyxoma peritonei. ( Sugarbaker, PH, 2017)
"Mitomycin C has been the most commonly used chemotherapeutic in HIPEC for the past several decades."1.46Pulmonary toxicity after intraperitoneal mitomycin C: a case report of a rare complication of HIPEC. ( Abel, ML; Blazer, DG; Kokosis, G, 2017)
"Conclusions Prophylactic HIPEC for appendiceal neoplasms is feasible, safe and may be performed laparoscopically."1.43Prophylactic hyperthermic intraperitoneal chemotherapy in patients with epithelial appendiceal neoplasms. ( Aycart, SN; Berger, Y; Hiotis, S; Labow, DM; Sarpel, U; Shtilbans, T; Tuvin, D, 2016)
"Mitomycin C (88."1.40Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: outcomes from a single tertiary institution. ( Hiotis, S; Jibara, G; Labow, DM; Romanoff, A; Sarpel, U; Shrager, B; Tabrizian, P; Yang, MJ, 2014)
"Most classifications of mucinous appendiceal neoplasms (MAN) do not take into consideration the type of primary tumor or the burden of peritoneal disease."1.40Evaluation of a new staging classification and a Peritoneal Surface Disease Severity Score (PSDSS) in 229 patients with mucinous appendiceal neoplasms with or without peritoneal dissemination. ( Esquivel, J; Garcia, SS; Hicken, W; Seibel, J; Shekitka, K; Trout, R, 2014)
"Among the CRC and appendiceal cancer group the median overall survival was 20."1.40[Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colorectal and appendiceal origin]. ( Aderka, D; Berger, Y; Brenner, B; Golan, T; Gutman, M; Lebedyev, A; Levi, Y; Natur, M; Nevler, A; Purim, O; Zbar, AP, 2014)
"Patients with PC from colorectal or appendiceal cancer, pseudomyxoma peritonei or malignant peritoneal mesothelioma referred to the single national HIPEC centre were prospectively registered from June 2006 to July 2012."1.39Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: the Danish experience. ( Hagemann-Madsen, R; Iversen, LH; Laurberg, S; Rasmussen, PC, 2013)
"Severe obesity is associated with decreased long-term survival only in patients with LGA primary disease; however, application of CRS/HIPEC still offers meaningful prolongation of life."1.39Obesity and peritoneal surface disease: outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for appendiceal and colon primary tumors. ( Levine, EA; Randle, RW; Shen, P; Stewart, JH; Swett, KR; Swords, DS; Votanopoulos, KI, 2013)
"Neutropenia is a frequent complication associated with MMC-HIPEC."1.35Incidence, risk factors, and impact of severe neutropenia after hyperthermic intraperitoneal mitomycin C. ( Armstrong, TS; Eng, C; Gonzalez-Moreno, S; Katz, MH; Lambert, DH; Lambert, LA; Lee, JJ; Liu, S; Mansfield, PF; Tansey, P; Tortorice, ML; Wolff, RA, 2009)
"Prognosis was poorer for patients with colon cancer, who had a median survival of 7."1.32Total abdominal colectomy, pelvic peritonectomy, and end-ileostomy for the surgical palliation of mucinous peritoneal carcinomatosis from non-gynecologic cancer. ( Karakozis, S; Stamou, KM; Sugarbaker, PH, 2003)
"The outcome of patients with mucinous appendiceal neoplasms with peritoneal surface dissemination has changed as a result of a better understanding of the clinical and pathologic features of this disease."1.31Second-look surgery in patients with peritoneal dissemination from appendiceal malignancy: analysis of prognostic factors in 98 patients. ( Esquivel, J; Sugarbaker, PH, 2001)
"The role in colorectal cancer is less clear, although there are some reports that suggest a benefit."1.30Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer. ( Clingan, P; Horsell, KW; King, DW; Merten, S; Morris, DL, 1999)
"Peritoneal carcinomatosis is a treatable condition in selected patients with a possibility for long-term disease-free survival."1.29Prognostic features for peritoneal carcinomatosis in colorectal and appendiceal cancer patients when treated by cytoreductive surgery and intraperitoneal chemotherapy. ( Chang, D; Koslowe, P; Sugarbaker, PH, 1996)
"Peritoneal carcinomatosis has been regarded as a uniformly lethal clinical entity with no specific plan for management."1.29Treatment of peritoneal carcinomatosis from colon or appendiceal cancer with induction intraperitoneal chemotherapy. ( Sugarbaker, PH, 1996)
"Pseudomyxoma peritonei is a rare disease caused by a perforated adenoma of the appendix."1.29Patterns of failure following treatment of pseudomyxoma peritonei of appendiceal origin. ( Sugarbaker, PH; Zoetmulder, FA, 1996)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (12.50)18.2507
2000's17 (26.56)29.6817
2010's28 (43.75)24.3611
2020's11 (17.19)2.80

Authors

AuthorsStudies
Ghelardi, F1
Raimondi, A1
Morano, F1
Randon, G1
Pannone, A1
Guaglio, M1
Mazzoli, G1
Nasca, V1
Milione, M1
Leoncini, G1
Sabella, G1
Greco, GF1
Lampis, BR1
Galassi, M1
Delfanti, S1
Nannini, M1
Intini, R1
Baratti, D2
Di Bartolomeo, M1
Deraco, M2
Pietrantonio, F1
Bartlett, K1
Derrington, S1
Jariwala, N1
Mai, C1
Koo, B1
Somashekhar, SP1
Yethadka, R1
Kumar C, R1
Ashwin, KR1
Zaveri, S1
Rauthan, A1
Moaven, O1
Votanopoulos, KI3
Shen, P5
Mansfield, P2
Bartlett, DL2
Russell, G3
McQuellon, R1
Stewart, JH4
Levine, EA5
Tun, S1
Eng, OS1
Malec, M1
Li, XB1
Ma, R1
Ji, ZH1
Lin, YL1
Zhang, J1
Yang, ZR1
Chen, LF1
Yan, FC1
Li, Y1
Sugarbaker, PH18
Soucisse, ML1
Lansom, J1
Alshahrani, MS1
Morris, DL4
Shariff, US1
Chandrakumaran, K5
Dayal, S1
Mohamed, F5
Cecil, TD3
Moran, BJ3
Barrak, D1
Desale, S1
Yoon, JJ1
Dugan, MM1
Kodavanti, PP1
Sampah, ME1
Benzaquen, E1
Wang, Y1
Wiseman, S1
Rosenfeld, V1
Sideris, L3
Dubé, P3
Pelletier, JS1
Vanounou, T1
Zhang, C1
Plambeck, BD1
Craig, ME1
Tu, A1
Mikus, RJ1
Shostrom, V1
McDermott, SP1
Igbinigie, I1
Brown, K1
Cushman-Vokoun, A1
Foster, JM1
Fenstermaker, J1
Bartlett, D1
Aziz, O1
Jaradat, I1
Chakrabarty, B1
Selvasekar, CR1
Fulford, PE1
Saunders, MP1
Renehan, AG1
Wilson, MS1
O'Dwyer, ST1
García, KM1
Flores, KM1
Ruiz, A1
González, FL1
Rodríguez, ÁM1
Narasimhan, V1
Pham, T1
Warrier, S1
Craig Lynch, A1
Michael, M1
Tie, J1
Ramsay, R1
Heriot, A1
Turner, KM1
Hanna, NN1
Zhu, Y1
Jain, A1
Kesmodel, SB1
Switzer, RA1
Taylor, LM1
Richard Alexander, H1
Iversen, LH1
Rasmussen, PC1
Hagemann-Madsen, R1
Laurberg, S1
Swords, DS1
Swett, KR1
Randle, RW1
Sardi, A1
Jimenez, WA1
Nieroda, C1
Sittig, M1
Macdonald, R1
Gushchin, V2
Fish, R1
Selvasekar, C1
Crichton, P1
Wilson, M1
Fulford, P1
Renehan, A1
O'Dwyer, S1
McConnell, YJ1
Mack, LA2
Gui, X1
Carr, NJ1
Temple, WJ2
Tabrizian, P1
Shrager, B1
Jibara, G1
Yang, MJ1
Romanoff, A1
Hiotis, S2
Sarpel, U2
Labow, DM2
Esquivel, J3
Garcia, SS1
Hicken, W1
Seibel, J1
Shekitka, K1
Trout, R1
Berger, Y2
Zbar, AP1
Lebedyev, A1
Levi, Y1
Nevler, A1
Aderka, D1
Golan, T1
Purim, O1
Brenner, B1
Natur, M1
Gutman, M1
Lord, AC1
Shihab, O1
Sparks, DS1
Morris, B1
Xu, W1
Fulton, J1
Atkinson, V1
Meade, B1
Lutton, N1
Moran, B2
Cecil, T2
Arnold, S1
Venkatasubramaniam, A1
Sabourin, JC1
Tuvin, D1
Aycart, SN1
Shtilbans, T1
Di Fabio, F1
Mehta, A1
Abel, ML1
Kokosis, G1
Blazer, DG1
Lanuke, K1
Mitchell, A1
Drolet, P1
Leblanc, G1
Leclerc, YE1
Lambert, LA2
Armstrong, TS1
Lee, JJ1
Liu, S1
Katz, MH1
Eng, C1
Wolff, RA1
Tortorice, ML1
Tansey, P1
Gonzalez-Moreno, S3
Lambert, DH1
Mansfield, PF2
Van der Speeten, K1
Stuart, OA1
Chang, D4
Mahteme, H1
Austin, F1
Mavanur, A1
Sathaiah, M1
Steel, J1
Lenzner, D1
Ramalingam, L1
Holtzman, M1
Ahrendt, S1
Pingpank, J1
Zeh, HJ1
Choudry, HA1
Votanopoulos, K1
Ihemelandu, C1
Stewart, J1
Klaver, YL1
Chua, TC1
Verwaal, VJ1
de Hingh, IH1
Harrison, LE1
Tiesi, G1
Razavi, R1
Wang, CC1
Stamou, KM1
Karakozis, S1
Brun, E1
Alderman, R1
Edwards, G1
Marquardt, CE1
Yan, TD2
Links, M1
Xu, ZY1
Kam, PC1
Glenn, D1
Bijelic, L1
McQuellon, RP2
Russell, GB2
Saunders, W1
Kusamura, S1
Nonaka, D1
Langer, M1
Andreola, S1
Favaro, M1
Gavazzi, C1
Laterza, B1
Jablonski, KA1
Koslowe, P1
Zoetmulder, FA1
Hosch, WP1
Rudi, J1
Stremmel, W1
Horsell, KW1
Merten, S1
Clingan, P1
King, DW1
Sasaki, A1
Terashima, M1
Okamoto, K1
Ikeda, K1
Takagane, A1
Takiyama, I1
Shimada, Y1
Yamamoto, M1
Nakajima, J1
Sasaki, N1
Saito, K1
Loggie, BW1
Fleming, RA1
Geisinger, KR1
Landy, D1
Jaffe, G1
Pascal, R1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diagnostic Value of Diffusion-weighted Magnetic Resonance Imaging for Detection of Peritoneal Recurrence in Patients With High-risk Colorectal and Appendiceal Neoplasms : a Pilot Study[NCT05623787]30 participants (Anticipated)Interventional2022-09-01Recruiting
A Phase II Trial to Analyze Clinical and Pharmacological Properties for Severe Neutropenia After Cytoreductive Surgery Followed by Hyperthermic Intraperitoneal Chemotherapy Using Mitomycin-C[NCT05513183]74 participants (Actual)Observational2021-05-20Completed
Thrombin Generation and Platelet Activation in Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy[NCT03034850]27 participants (Actual)Observational2015-04-30Completed
Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy[NCT02741167]90 participants (Anticipated)Observational2016-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for mitomycin and Appendiceal Cancer

ArticleYear
Mucinous appendiceal neoplasms with or without pseudomyxoma peritonei: a review.
    ANZ journal of surgery, 2020, Volume: 90, Issue:10

    Topics: Appendiceal Neoplasms; Cytoreduction Surgical Procedures; Humans; Hyperthermia, Induced; Mitomycin;

2020
Appendiceal tumors with glandular and neuroendocrine features exhibiting peritoneal metastases - Critical evaluation of outcome following cytoreductive surgery with perioperative chemotherapy.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:6

    Topics: Adenocarcinoma; Administration, Intravenous; Adult; Aged; Antineoplastic Combined Chemotherapy Proto

2021
Pseudomyxoma Peritonei: Case Report and Literature Review.
    Journal of gastrointestinal cancer, 2019, Volume: 50, Issue:4

    Topics: Appendiceal Neoplasms; Appendix; Biopsy; Colectomy; Combined Modality Therapy; Cytoreduction Surgica

2019
Outcomes from cytoreduction and hyperthermic intraperitoneal chemotherapy for appendiceal epithelial neoplasms.
    ANZ journal of surgery, 2019, Volume: 89, Issue:9

    Topics: Antibiotics, Antineoplastic; Appendiceal Neoplasms; Australia; Chemotherapy, Cancer, Regional Perfus

2019
[Peritoneal tumor pathology: case n(o) 2: a "sticky" peritoneal tumor].
    Annales de pathologie, 2015, Volume: 35, Issue:4

    Topics: Abdominal Pain; Adult; Antineoplastic Agents, Alkylating; Appendectomy; Appendiceal Neoplasms; Combi

2015
New standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome?
    The Lancet. Oncology, 2006, Volume: 7, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Combined Modality Therapy; Fl

2006

Trials

8 trials available for mitomycin and Appendiceal Cancer

ArticleYear
Health-Related Quality of Life After Cytoreductive Surgery/HIPEC for Mucinous Appendiceal Cancer: Results of a Multicenter Randomized Trial Comparing Oxaliplatin and Mitomycin.
    Annals of surgical oncology, 2020, Volume: 27, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Appendiceal Neoplas

2020
A Multicenter Randomized Trial to Evaluate Hematologic Toxicities after Hyperthermic Intraperitoneal Chemotherapy with Oxaliplatin or Mitomycin in Patients with Appendiceal Tumors.
    Journal of the American College of Surgeons, 2018, Volume: 226, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Appendectomy; Appendiceal Neoplasms; Blood Ce

2018
Risk-reducing laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for low-grade appendiceal mucinous neoplasm: early outcomes and technique.
    Surgical endoscopy, 2014, Volume: 28, Issue:1

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Appendiceal Neoplasms; Combined Modality Therapy; Drug Admini

2014
Phase II study of regional treatment for peritoneal carcinomatosis.
    American journal of surgery, 2009, Volume: 197, Issue:5

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Chemotherapy, Cancer, R

2009
Secondary cytoreductive surgery and peri-operative intraperitoneal chemotherapy for peritoneal recurrence of colorectal and appendiceal peritoneal carcinomatosis following prior primary cytoreduction.
    Journal of surgical oncology, 2013, Volume: 107, Issue:6

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Appendiceal Neoplasms; Chemotherapy, Adjuvant; Chemoth

2013
A phase I trial of thermal sensitization using induced oxidative stress in the context of HIPEC.
    Annals of surgical oncology, 2013, Volume: 20, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hum

2013
Cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei from appendiceal mucinous neoplasms.
    The British journal of surgery, 2006, Volume: 93, Issue:10

    Topics: Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplas

2006
Prognostic features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intraperitoneal chemotherapy.
    Annals of surgery, 1995, Volume: 221, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Appendicea

1995

Other Studies

50 other studies available for mitomycin and Appendiceal Cancer

ArticleYear
Mytomicin-C, Metronomic Capecitabine, and Bevacizumab in Patients With Unresectable or Relapsed Pseudomyxoma Peritonei of Appendiceal Origin.
    Clinical colorectal cancer, 2023, Volume: 22, Issue:4

    Topics: Appendiceal Neoplasms; Bevacizumab; Capecitabine; Disease Progression; Humans; Hyperthermia, Induced

2023
Scrotal ulceration: a complication of hyperthermic intraperitoneal chemotherapy and subsequent treatment with dimethyl sulfoxide.
    Cutis, 2019, Volume: 104, Issue:1

    Topics: Adenocarcinoma; Administration, Cutaneous; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Dimet

2019
Toxicity profile of chemotherapy agents used in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2020, Volume: 46, Issue:4 Pt A

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neop

2020
Health-Related Quality of Life After Cytoreductive Surgery/HIPEC for Mucinous Appendiceal Cancer: Results of a Multicenter Randomized Trial Comparing Oxaliplatin and Mitomycin.
    Annals of surgical oncology, 2020, Volume: 27, Issue:3

    Topics: Appendiceal Neoplasms; Cytoreduction Surgical Procedures; Humans; Hyperthermia, Induced; Mitomycin;

2020
Perioperative safety after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei from appendiceal origin: Experience on 254 patients from a single center.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2020, Volume: 46, Issue:4 Pt A

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasm

2020
Peritoneal carcinomatosis of unknown primary site, a study of 25 patients over 30 years.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2020, Volume: 46, Issue:10 Pt A

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms;

2020
Mode of Presentation in 1070 Patients With Perforated Epithelial Appendiceal Tumors, Predominantly with Pseudomyxoma Peritonei.
    Diseases of the colon and rectum, 2020, Volume: 63, Issue:9

    Topics: Adenocarcinoma, Mucinous; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Appendicitis; Bi

2020
Morbidity associated with the use of oxaliplatin versus mitomycin C in hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis of colorectal or appendiceal origin: a multi-institutional comparative study.
    Canadian journal of surgery. Journal canadien de chirurgie, 2021, 03-02, Volume: 64, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Colorectal Neoplasms; Female; Humans; Hyp

2021
Exploring the prognostic and therapeutic utility of expanded mutation profiling in appendix peritoneal metastasis managed with CRS/HIPEC.
    Journal of surgical oncology, 2021, Volume: 123, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Appendiceal Neoplasms; Combined Modality Therapy; Cytoreduction Surg

2021
Discussion.
    Journal of the American College of Surgeons, 2018, Volume: 226, Issue:4

    Topics: Appendiceal Neoplasms; Humans; Hyperthermia, Induced; Mitomycin; Oxaliplatin

2018
Predicting Survival After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Appendix Adenocarcinoma.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Colectomy; Cytoredu

2018
Assessment of neoadjuvant chemotherapy on operative parameters and outcome in patients with peritoneal dissemination from high-grade appendiceal cancer.
    Annals of surgical oncology, 2013, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2013
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: the Danish experience.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Carcinoma; Colorectal Neoplasms; Co

2013
Obesity and peritoneal surface disease: outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for appendiceal and colon primary tumors.
    Annals of surgical oncology, 2013, Volume: 20, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Appendic

2013
Repeated cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis from appendiceal cancer: analysis of survival outcomes.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2013, Volume: 39, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Carboplatin; Car

2013
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: an emerging treatment option for advanced goblet cell tumors of the appendix.
    Annals of surgical oncology, 2014, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Carcinoembryonic Antigen; Carcin

2014
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: outcomes from a single tertiary institution.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2014, Volume: 18, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Blood Transfusio

2014
Evaluation of a new staging classification and a Peritoneal Surface Disease Severity Score (PSDSS) in 229 patients with mucinous appendiceal neoplasms with or without peritoneal dissemination.
    Journal of surgical oncology, 2014, Volume: 110, Issue:6

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Alkylating Agents; Appendectomy; Appendiceal Neoplasms; Chemo

2014
[Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colorectal and appendiceal origin].
    Harefuah, 2014, Volume: 153, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Protocols; Appendiceal Neoplasms; Carcinoma; Chemotherap

2014
Recurrence and outcome after complete tumour removal and hyperthermic intraperitoneal chemotherapy in 512 patients with pseudomyxoma peritonei from perforated appendiceal mucinous tumours.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Appendiceal Neoplas

2015
Cytoreductive surgery and heated intraperitoneal chemotherapy for peritoneal carcinomatosis secondary to mucinous adenocarcinoma of the appendix.
    International surgery, 2015, Volume: 100, Issue:1

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Chemother

2015
The results of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in 1200 patients with peritoneal malignancy.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2015, Volume: 17, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Cisplatin; Colorectal Neoplas

2015
Prophylactic hyperthermic intraperitoneal chemotherapy in patients with epithelial appendiceal neoplasms.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2016, Volume: 32, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Chemotherapy, Cancer, Regional Perf

2016
Advanced Pseudomyxoma Peritonei Requiring Gastrectomy to Achieve Complete Cytoreduction Results in Good Long-Term Oncologic Outcomes.
    Annals of surgical oncology, 2016, Volume: 23, Issue:13

    Topics: Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; CA-125 Antigen; CA-19-9 Antigen; Carcinoem

2016
Management of an inguinal hernia in patients with pseudomyxoma peritonei.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2017, Volume: 43, Issue:6

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal N

2017
Pulmonary toxicity after intraperitoneal mitomycin C: a case report of a rare complication of HIPEC.
    World journal of surgical oncology, 2017, Feb-20, Volume: 15, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Chemotherapy, Cancer,

2017
Surgical cytoreduction and intraperitoneal chemotherapy for peritoneal carcinomatosis arising from the appendix.
    Canadian journal of surgery. Journal canadien de chirurgie, 2009, Volume: 52, Issue:2

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Camptothecin; C

2009
Incidence, risk factors, and impact of severe neutropenia after hyperthermic intraperitoneal mitomycin C.
    Annals of surgical oncology, 2009, Volume: 16, Issue:8

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Combined Modality Therapy; Female;

2009
Changes induced by surgical and clinical factors in the pharmacology of intraperitoneal mitomycin C in 145 patients with peritoneal carcinomatosis.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Ap

2011
Aggressive management of peritoneal carcinomatosis from mucinous appendiceal neoplasms.
    Annals of surgical oncology, 2012, Volume: 19, Issue:5

    Topics: Adenocarcinoma, Mucinous; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Disease-Free Survival;

2012
A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C.
    The Journal of surgical research, 2013, Volume: 179, Issue:1

    Topics: Adult; Antineoplastic Agents; Appendiceal Neoplasms; Blood Platelets; Colorectal Neoplasms; Combined

2013
A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C.
    The Journal of surgical research, 2013, Volume: 179, Issue:1

    Topics: Adult; Antineoplastic Agents; Appendiceal Neoplasms; Blood Platelets; Colorectal Neoplasms; Combined

2013
A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C.
    The Journal of surgical research, 2013, Volume: 179, Issue:1

    Topics: Adult; Antineoplastic Agents; Appendiceal Neoplasms; Blood Platelets; Colorectal Neoplasms; Combined

2013
A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C.
    The Journal of surgical research, 2013, Volume: 179, Issue:1

    Topics: Adult; Antineoplastic Agents; Appendiceal Neoplasms; Blood Platelets; Colorectal Neoplasms; Combined

2013
Third look surgery and beyond for appendiceal malignancy with peritoneal dissemination.
    Journal of surgical oncology, 2003, Volume: 83, Issue:1

    Topics: Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplas

2003
Total abdominal colectomy, pelvic peritonectomy, and end-ileostomy for the surgical palliation of mucinous peritoneal carcinomatosis from non-gynecologic cancer.
    Journal of surgical oncology, 2003, Volume: 83, Issue:4

    Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasm

2003
Re: Verwaal VJ, van Tinteren H, Ruth SV, et al.: Toxicity of cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy. J Surg Oncol 2004; 85:61-67.
    Journal of surgical oncology, 2004, Dec-15, Volume: 88, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Chemotherapy, Adjuvant; Color

2004
Lymph node metastasis in epithelial malignancies of the appendix with peritoneal dissemination does not reduce survival in patients treated by cytoreductive surgery and perioperative intraperitoneal chemotherapy.
    Annals of surgical oncology, 2005, Volume: 12, Issue:1

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Combine

2005
An instrument to provide containment of intraoperative intraperitoneal chemotherapy with optimized distribution.
    Journal of surgical oncology, 2005, Nov-01, Volume: 92, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Cisplatin; Containment of Bio

2005
Prospective morbidity and mortality assessment of cytoreductive surgery plus perioperative intraperitoneal chemotherapy to treat peritoneal dissemination of appendiceal mucinous malignancy.
    Annals of surgical oncology, 2006, Volume: 13, Issue:5

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal N

2006
Interstitial pneumonitis: an exceptional toxicity of hyperthermic intraperitoneal mitomycin C.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2008, Volume: 34, Issue:4

    Topics: Antibiotics, Antineoplastic; Appendiceal Neoplasms; Female; Humans; Hyperthermia, Induced; Infusions

2008
Critical analysis of treatment failure after complete cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal dissemination from appendiceal mucinous neoplasms.
    Annals of surgical oncology, 2007, Volume: 14, Issue:8

    Topics: Adenocarcinoma, Mucinous; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Appen

2007
Survival and health outcomes after cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of appendiceal origin.
    Annals of surgical oncology, 2008, Volume: 15, Issue:1

    Topics: Activities of Daily Living; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplas

2008
Pseudomyxoma peritonei: clinical pathological and biological prognostic factors in patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).
    Annals of surgical oncology, 2008, Volume: 15, Issue:2

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Biomarker

2008
Prognostic features for peritoneal carcinomatosis in colorectal and appendiceal cancer patients when treated by cytoreductive surgery and intraperitoneal chemotherapy.
    Cancer treatment and research, 1996, Volume: 81

    Topics: Appendiceal Neoplasms; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans

1996
Treatment of peritoneal carcinomatosis from colon or appendiceal cancer with induction intraperitoneal chemotherapy.
    Cancer treatment and research, 1996, Volume: 82

    Topics: Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Colonic Neoplasms; Female; Fluorouracil;

1996
Patterns of failure following treatment of pseudomyxoma peritonei of appendiceal origin.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:10

    Topics: Abdomen; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Chemotherapy,

1996
Therapy of pseudomyxoma peritonei of appendiceal origin--surgical resection and intraperitoneal chemotherapy.
    Zeitschrift fur Gastroenterologie, 1999, Volume: 37, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Chemotherapy, Ad

1999
Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer.
    The Australian and New Zealand journal of surgery, 1999, Volume: 69, Issue:10

    Topics: Abscess; Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic;

1999
[Intraperitoneal administration of a combined CDDP, 5-FU and MMC therapy for pseudomyxoma peritonei].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal Neoplasms; Cisplati

1999
Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of gastrointestinal origin.
    The American surgeon, 2000, Volume: 66, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Chem

2000
Second-look surgery in patients with peritoneal dissemination from appendiceal malignancy: analysis of prognostic factors in 98 patients.
    Annals of surgery, 2001, Volume: 234, Issue:2

    Topics: Adenocarcinoma, Mucinous; Appendiceal Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy;

2001
Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix.
    Cancer, 1990, Apr-01, Volume: 65, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Colonic Neoplasm

1990