mitomycin has been researched along with Animal Mammary Carcinoma in 8 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined whether D-Fraction could decrease the effective dosage of the chemotherapeutic agent, mitomycin-C (MMC), necessary to control carcinoma in mice." | 3.73 | Maitake D-Fraction enhances antitumor effects and reduces immunosuppression by mitomycin-C in tumor-bearing mice. ( Asakawa, A; Hayashi, M; Inui, A; Kodama, N; Murata, Y; Nanba, H; Sakai, N, 2005) |
| "Hereditary cases of breast and ovarian cancer are often attributed to germ-line mutations of the BRCA1 tumor suppressor gene." | 1.35 | E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. ( Baer, R; Cheng, JT; Jasin, M; Lokshin, M; Ludwig, T; Modi, AP; Reid, LJ; Shakya, R, 2008) |
| " The seven agents combined with CI-973 were mitomycin C, cyclophosphamide, doxorubicin, vinblastine, etoposide, ifosfamide, and methotrexate." | 1.29 | Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo. ( Elliott, WL; Howard, CT; Leopold, WR; Roberts, BJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paz, MM | 1 |
| Ladwa, S | 1 |
| Champeil, E | 1 |
| Liu, Y | 1 |
| Rockwell, S | 4 |
| Boamah, EK | 1 |
| Bargonetti, J | 1 |
| Callahan, J | 1 |
| Roach, J | 1 |
| Tomasz, M | 4 |
| Reid, LJ | 1 |
| Shakya, R | 1 |
| Modi, AP | 1 |
| Lokshin, M | 1 |
| Cheng, JT | 1 |
| Jasin, M | 1 |
| Baer, R | 1 |
| Ludwig, T | 1 |
| Kodama, N | 1 |
| Murata, Y | 1 |
| Asakawa, A | 1 |
| Inui, A | 1 |
| Hayashi, M | 1 |
| Sakai, N | 1 |
| Nanba, H | 1 |
| Shao, Y | 1 |
| Pardini, L | 1 |
| Pardini, RS | 1 |
| Elliott, WL | 1 |
| Roberts, BJ | 1 |
| Howard, CT | 1 |
| Leopold, WR | 1 |
| Palom, Y | 3 |
| Belcourt, MF | 3 |
| Kumar, GS | 1 |
| Arai, H | 1 |
| Kasai, M | 1 |
| Sartorelli, AC | 3 |
| Musser, SM | 1 |
| Tang, LQ | 1 |
| Mehta, SS | 1 |
| Pritsos, CA | 1 |
| Pritsos, KL | 1 |
8 other studies available for mitomycin and Animal Mammary Carcinoma
| Article | Year |
|---|---|
Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cross-Linking Rea | 2008 |
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks.
Topics: Animals; BRCA1 Protein; Breast Neoplasms; Cell Line; Chromosome Aberrations; Cross-Linking Reagents; | 2008 |
Maitake D-Fraction enhances antitumor effects and reduces immunosuppression by mitomycin-C in tumor-bearing mice.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers, Tumor; Carcinoma; Cell Line, Tumor; Dose-Response | 2005 |
Enhancement of the antineoplastic effect of mitomycin C by dietary fat.
Topics: Animals; Cytochrome Reductases; Cytochrome-B(5) Reductase; Dietary Fats; Drug Screening Assays, Anti | 1994 |
Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colonic Neoplasms; Cyclophosph | 1994 |
Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.
Topics: Animals; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; Dose-Response Relationship, | 1998 |
Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells.
Topics: Animals; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Cross-Linking Reagents; | 2000 |
Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol.
Topics: Animals; Biological Transport; Cell Division; Cell-Free System; Dicumarol; DNA Adducts; Drug Interac | 2001 |