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mitomycin and Anemia, Hemolytic

mitomycin has been researched along with Anemia, Hemolytic in 23 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).

Research Excerpts

ExcerptRelevanceReference
"After treatment with mitomycin C, a patient developed pulmonary hypertension with interstitial infiltrates, microangiopathic hemolytic anemia, systemic hypertension, and renal failure with the nephrotic syndrome."7.67Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome. ( McCarthy, JT; Staats, BA, 1986)
"A thrombotic microangiopathy resembling the hemolytic uremic syndrome was diagnosed in 12 patients with adenocarcinoma, in whom the tumor was in complete or near-complete remission after treatment with mitomycin C-containing drug regimens."7.67Carcinoma-associated hemolytic-uremic syndrome: a complication of mitomycin C chemotherapy. ( Cantrell, JE; Phillips, TM; Schein, PS, 1985)
"We examined various markers in 17 patients with thrombotic thrombocytopenic purpura (TTP), 13 with red cell fragmentation syndrome (RCFS) induced by mitomycin C, and 36 with RCFS caused by disseminated intravascular coagulation (DIC)."3.69[Plasma level of various markers in patients with thrombotic thrombocytopenic purpura]. ( Shirakawa, S; Tamaki, S; Wada, H, 1994)
"A 68-year-old man was treated with FAM (5-fluorouracil, doxorubicin [Adriamycin], mitomycin-C) for metastic gastric adenocarcinoma."3.67Pulmonary veno-occlusive disease associated with microangiopathic hemolytic anemia and chemotherapy of gastric adenocarcinoma. ( Kerwin, DM; Smith, FP; Tsou, E; Waldhorn, RE, 1984)
"After treatment with mitomycin C, a patient developed pulmonary hypertension with interstitial infiltrates, microangiopathic hemolytic anemia, systemic hypertension, and renal failure with the nephrotic syndrome."3.67Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome. ( McCarthy, JT; Staats, BA, 1986)
"A thrombotic microangiopathy resembling the hemolytic uremic syndrome was diagnosed in 12 patients with adenocarcinoma, in whom the tumor was in complete or near-complete remission after treatment with mitomycin C-containing drug regimens."3.67Carcinoma-associated hemolytic-uremic syndrome: a complication of mitomycin C chemotherapy. ( Cantrell, JE; Phillips, TM; Schein, PS, 1985)
"Following gastrectomy for locally advanced adenocarcinomas, three patients developed microangiopathic hemolytic anemia and renal failure shortly after completing courses of adjuvant chemotherapy with mitomycin and 5-FU."3.66Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome. ( Band, PR; Bettez, P; Giroux, L; Gruber, J; Jolivet, J; Laurin, S, 1983)
"Although fatigue was the most frequently encountered toxicity safety profiles were generally predictable and manageable."2.73Mitomycin C plus S-1 as second-line therapy in patients with advanced gastric cancer: a noncomparative phase II study. ( Cho, EK; Chung, M; Hong, J; Kim, YS; Lee, JH; Lee, WK; Nam, E; Park, J; Park, SH; Shin, DB, 2008)
"The patient was first diagnosed with squamous cell carcinoma of the anus 1 year before admission."1.32Cases from the Osler Medical Service at Johns Hopkins University. ( Brown, C; Zetola-Burneo, N, 2004)
"A case of advanced gastric cancer associated with metastatic carcinomatosis of the bone marrow, microangiopathic hemolytic anemia (MAHA) and disseminated intravascular coagulation (DIC) was reported."1.27[Microangiopathic hemolytic anemia associated with gastric cancer]. ( Hattori, T; Kanou, T; Kuramoto, J; Miura, K; Niimoto, M; Nosou, Y; Yanagawa, E; Yoshinaka, K, 1986)
"The mitomycin C dose was less than or equal to 15 mg/m2 every 53rd day and the total cumulative dose was between 25 and 250 mg."1.27Renal complications of mitomycin C therapy with special reference to the total dose. ( Nordman, E; Valavaara, R, 1985)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199016 (69.57)18.7374
1990's4 (17.39)18.2507
2000's3 (13.04)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, SH1
Kim, YS1
Hong, J1
Park, J1
Nam, E1
Cho, EK1
Shin, DB1
Lee, JH1
Lee, WK1
Chung, M1
Wen, MC1
Chen, CH1
Ho, WL1
Zetola-Burneo, N1
Brown, C1
Jolivet, J1
Giroux, L1
Laurin, S1
Gruber, J1
Bettez, P1
Band, PR1
Perry, DJ1
Doll, DC1
Weiss, RB1
Ravikumar, TS1
Sibley, R1
Reed, K1
Grage, TB1
Waldhorn, RE1
Tsou, E1
Smith, FP1
Kerwin, DM1
Ito, S1
Hirono, S1
Kobayashi, M1
Wada, H2
Wakita, Y1
Shimura, M1
Nakase, T1
Hiyoyama, K1
Nagaya, S1
Minami, N1
Nakano, T1
Shiku, H1
Tamaki, S1
Shirakawa, S1
Godes, M1
Camps, C1
Martínez, A1
Mackintosh, J1
Sagawa, M1
Sakuma, T1
Takahashi, S1
Usuda, K1
Satoh, M1
Kamma, K1
Ohta, S1
Nagamoto, N1
Imai, T1
Saitoh, Y1
McCarthy, JT1
Staats, BA1
Kanou, T1
Nosou, Y1
Yoshinaka, K1
Yanagawa, E1
Niimoto, M1
Hattori, T1
Miura, K1
Kuramoto, J1
Claycomb, CL1
Berkovic, M1
Hostetter, AL1
Tubbs, RR1
Ziegler, T1
Gephardt, GN1
McMahon, JT1
Schreiber, MJ1
Yasunaga, C1
Komota, T1
Mimura, K1
Kinjyo, M1
Sueishi, K1
Hirose, T1
Hayano, K1
Fukui, H1
Otsuka, Y1
Hattori, S1
Valavaara, R1
Nordman, E1
Price, TM1
Murgo, AJ1
Keveney, JJ1
Miller-Hardy, D1
Kasprisin, DO1
Cantrell, JE1
Phillips, TM1
Schein, PS1

Reviews

1 review available for mitomycin and Anemia, Hemolytic

ArticleYear
Chemotherapeutic agents and the erythron.
    Cancer treatment reviews, 1983, Volume: 10, Issue:3

    Topics: Anemia, Hemolytic; Antibiotics, Antineoplastic; Antineoplastic Agents; Cisplatin; Erythrocyte Membra

1983

Trials

1 trial available for mitomycin and Anemia, Hemolytic

ArticleYear
Mitomycin C plus S-1 as second-line therapy in patients with advanced gastric cancer: a noncomparative phase II study.
    Anti-cancer drugs, 2008, Volume: 19, Issue:3

    Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Disease Progression;

2008

Other Studies

21 other studies available for mitomycin and Anemia, Hemolytic

ArticleYear
Mitomycin C-induced renal insufficiency: a case report.
    The Kaohsiung journal of medical sciences, 2003, Volume: 19, Issue:6

    Topics: Anemia, Hemolytic; Antibiotics, Antineoplastic; Humans; Hypertension; Kidney Diseases; Male; Middle

2003
Cases from the Osler Medical Service at Johns Hopkins University.
    The American journal of medicine, 2004, Feb-01, Volume: 116, Issue:3

    Topics: Anemia, Hemolytic; Antibiotics, Antineoplastic; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Hu

2004
Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome.
    Cancer treatment reports, 1983, Volume: 67, Issue:5

    Topics: Adenocarcinoma; Adult; Anemia, Hemolytic; Drug Therapy, Combination; Female; Fluorouracil; Humans; K

1983
Reversible microangiopathic hemolytic anemia after mitomycin C.
    Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Aged; Anemia, Hemolytic; Antibiotics, Antineoplastic; Humans; Male; Mitomycin; Mitom

1983
Renal toxicity of mitomycin-C.
    American journal of clinical oncology, 1984, Volume: 7, Issue:3

    Topics: Adult; Aged; Anemia, Hemolytic; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases; K

1984
Pulmonary veno-occlusive disease associated with microangiopathic hemolytic anemia and chemotherapy of gastric adenocarcinoma.
    Medical and pediatric oncology, 1984, Volume: 12, Issue:6

    Topics: Adenocarcinoma; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin

1984
[Two cases with microangiopathic hemolytic anemia caused by anti-cancer drugs who improved rapidly after administration of aspirin and dipyridamole].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1982, Volume: 23, Issue:5

    Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Agents; Aspirin; Chromomycin A3; Dipyridamole; Female

1982
Decreased plasma tissue factor pathway inhibitor levels in patients with thrombotic thrombocytopenic purpura.
    Thrombosis and haemostasis, 1995, Volume: 73, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic; Combined Modality Therapy; Disseminat

1995
[Plasma level of various markers in patients with thrombotic thrombocytopenic purpura].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic; Biomarkers; Blood Coagulation Factors

1994
[Microangiopathic hemolytic anemia associated with mitomycin-C treatment].
    Anales de medicina interna (Madrid, Spain : 1984), 1991, Volume: 8, Issue:12

    Topics: Acute Kidney Injury; Anemia, Hemolytic; Humans; Male; Middle Aged; Mitomycin

1991
Cardiopulmonary complications of mitomycin-C.
    The Medical journal of Australia, 1990, Jan-01, Volume: 152, Issue:1

    Topics: Anemia, Hemolytic; Female; Heart Failure; Humans; Hypertension, Pulmonary; Middle Aged; Mitomycin; M

1990
[Microangiopathic hemolytic anemia (MAHA) and renal failure induced by anti-neoplastic agents--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:8

    Topics: Acute Kidney Injury; Aged; Anemia, Hemolytic; Antineoplastic Agents; Antineoplastic Combined Chemoth

1987
Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome.
    Chest, 1986, Volume: 89, Issue:4

    Topics: Adenocarcinoma; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Colonic N

1986
[Microangiopathic hemolytic anemia associated with gastric cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:9

    Topics: Adenocarcinoma; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Benzodiazep

1986
Microangiopathic hemolytic anemia, noncardiac pulmonary edema, and renal failure after treatment of metastatic adenocarcinoma of the colon with 5-fluorouracil and mitomycin-C: report of a case.
    The Journal of the American Osteopathic Association, 1986, Volume: 86, Issue:8

    Topics: Adenocarcinoma; Anemia, Hemolytic; Colonic Neoplasms; Female; Fluorouracil; Humans; Kidney Failure,

1986
Chronic glomerular microangiopathy complicating metastatic carcinoma.
    Human pathology, 1987, Volume: 18, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Anemia, Hemolytic; Blood Coagulation; Chronic Disease; Female; Hemolyti

1987
[Microangiopathic hemolytic anemia (MAHA) observed after administration of mitomycin C (MMC)].
    Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:7

    Topics: Adenocarcinoma; Anemia, Hemolytic; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Postoperative C

1987
[Three cases of renal failure associated with microangiopathic hemolytic anemia after mitomycin C therapy].
    Nihon Jinzo Gakkai shi, 1988, Volume: 30, Issue:7

    Topics: Adenocarcinoma; Aged; Anemia, Hemolytic; Breast Neoplasms; Female; Fluorouracil; Glomerulonephritis,

1988
Renal complications of mitomycin C therapy with special reference to the total dose.
    Cancer, 1985, Jan-01, Volume: 55, Issue:1

    Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Female;

1985
Renal failure and hemolytic anemia associated with mitomycin C. A case report.
    Cancer, 1985, Jan-01, Volume: 55, Issue:1

    Topics: Anemia, Hemolytic; Biopsy; Humans; Kidney Failure, Chronic; Male; Middle Aged; Mitomycin; Mitomycins

1985
Carcinoma-associated hemolytic-uremic syndrome: a complication of mitomycin C chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:5

    Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Anemia, Hemolytic; Antibiotics, Antineoplastic; Antigen-

1985