mitomycin has been researched along with Anemia, Aplastic in 40 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was conducted to differentiate between Fanconi anemia (FA) and "idiopathic" aplastic anemia on the basis of induced chromosomal breakage study with mitomycin C (MMC)." | 7.72 | Differentiation of Fanconi anemia from idiopathic aplastic anemia by induced chromosomal breakage study using mitomycin-C (MMC). ( Choudhry, VP; Kucheria, K; Talwar, R, 2004) |
| "Crosslink repair of mitomycin C-induced interstrand crosslinks was studied in exponentially growing and confluent normal human, transformed W138CT-1, Fanconi's anemia (FA) and xeroderma pigmentosum (XP) group-A fibroblasts by the assay methods of alkaline sucrose centrifugation, hydroxyapatite column chromatography and S1-nuclease digestion." | 7.66 | Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells. ( Fujiwara, Y, 1982) |
| "Chromosomal breakage was induced by MMC 0 ng/ml, 40 ng/ml, and 80 ng/ml." | 5.39 | [Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia]. ( Cai, XJ; Chen, XJ; Chen, YM; Guo, Y; Liu, F; Liu, Q; Liu, TF; Liu, XM; Ruan, M; Wang, SC; Yang, WY; Zhang, JY; Zhang, L; Zhu, XF; Zou, Y, 2013) |
| "Induced chromosomal breakage study was successful in 171 out of 205 aplastic anemia (AA) patients." | 5.39 | Differentiation of Fanconi anemia and aplastic anemia using mitomycin C test in Tunisia. ( Abdelhak, S; Abidli, N; Aissaoui, L; Amouri, A; Ayed, W; Bejaoui, M; Ben Halim, N; Ben Othmane, T; Ben Romdhane, N; Ben Youssef, Y; Chemkhi, I; Elloumi, M; Guermani, H; Hadiji, S; Hentati, S; Kammoun, L; Kilani, O; Mellouli, F; Talmoudi, F; Torjmane, L, 2013) |
| " The diagnostic feature of FA is increased chromosomal breakage in blood lymphocytes cultured with diepoxybutane or mitomycin C." | 3.80 | Comparison of chromosome breakage in non-mosaic and mosaic patients with Fanconi anemia, relatives, and patients with other inherited bone marrow failure syndromes. ( Alter, BP; Fargo, JH; Giri, N; Olson, SB; Rochowski, A; Savage, SA, 2014) |
| "Investigation of mitomycin C-induced chromosomal breakage was carried out in 163 pediatric patients with AA and siblings of the cases where diagnosis of FA was confirmed." | 3.79 | Cytogenetic assessment of Fanconi anemia in children with aplastic anemia in Tunisia. ( Abdelhak, S; Aissaoui, L; Amouri, A; Bejaoui, M; Benhalim, N; Dellagi, K; Hdiji, S; Kammoun, L; Lakhal, A; Meddeb, M; Mellouli, F; Othmen, TB; Ouederni, M; Talmoudi, F; Torjemane, L, 2013) |
| "This study was conducted to differentiate between Fanconi anemia (FA) and "idiopathic" aplastic anemia on the basis of induced chromosomal breakage study with mitomycin C (MMC)." | 3.72 | Differentiation of Fanconi anemia from idiopathic aplastic anemia by induced chromosomal breakage study using mitomycin-C (MMC). ( Choudhry, VP; Kucheria, K; Talwar, R, 2004) |
| "By comparing fibroblast strains derived from individuals exhibiting chromosome instability and/or mutagen hypersensitivity (Cockayne syndrome, ataxia telangiectasia, and Fanconi anemia) with strains derived from healthy donors, the fibroblast micronucleus assay has been established as a reproducible measure of the genotypic variation in spontaneous or mitomycin C (MMC)-induced chromosomal instability." | 3.67 | Micronucleus assay in human fibroblasts: a measure of spontaneous chromosomal instability and mutagen hypersensitivity. ( Dimnik, LS; Greentree, CL; Hennig, UG; Hoar, DI; Rudd, NL, 1988) |
| "Crosslink repair of mitomycin C-induced interstrand crosslinks was studied in exponentially growing and confluent normal human, transformed W138CT-1, Fanconi's anemia (FA) and xeroderma pigmentosum (XP) group-A fibroblasts by the assay methods of alkaline sucrose centrifugation, hydroxyapatite column chromatography and S1-nuclease digestion." | 3.66 | Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells. ( Fujiwara, Y, 1982) |
| "Chromosomal breakage was induced by MMC 0 ng/ml, 40 ng/ml, and 80 ng/ml." | 1.39 | [Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia]. ( Cai, XJ; Chen, XJ; Chen, YM; Guo, Y; Liu, F; Liu, Q; Liu, TF; Liu, XM; Ruan, M; Wang, SC; Yang, WY; Zhang, JY; Zhang, L; Zhu, XF; Zou, Y, 2013) |
| "Induced chromosomal breakage study was successful in 171 out of 205 aplastic anemia (AA) patients." | 1.39 | Differentiation of Fanconi anemia and aplastic anemia using mitomycin C test in Tunisia. ( Abdelhak, S; Abidli, N; Aissaoui, L; Amouri, A; Ayed, W; Bejaoui, M; Ben Halim, N; Ben Othmane, T; Ben Romdhane, N; Ben Youssef, Y; Chemkhi, I; Elloumi, M; Guermani, H; Hadiji, S; Hentati, S; Kammoun, L; Kilani, O; Mellouli, F; Talmoudi, F; Torjmane, L, 2013) |
| "Lymphocytes from two sisters with Fanconi's anemia (FA) were studied for cell cycle kinetics, sister chromatid exchanges (SCEs), and chromosomal aberrations when they had undergone one, two, or three or more divisions in mitomycin C (MMC)-treated cultures." | 1.27 | Proliferative kinetics and mitomycin C-induced chromosome damage in Fanconi's anemia lymphocytes. ( Koizumi, A; Miura, K; Morimoto, K, 1983) |
| "These included cells from patients with Fanconi's anemia (FA), dyskeratosis congenita (DC) a disorder related to FA, Gardner's syndrome (GS) and xeroderma pigmentosum grop C (XPC)." | 1.27 | Suppression of cytotoxic effect of mitomycin-C by superoxide dismutase in Fanconi's anemia and dyskeratosis congenita fibroblasts. ( Little, JB; Nagasawa, H, 1983) |
| "The results indicate that Fanconi's anemia lymphocytes fail to exhibit an increased sensitivity to the antimitotic and clastogenic effects of paraquat and streptonigrin." | 1.27 | Cytogenetic toxicity of paraquat and streptonigrin in Fanconi's anemia. ( Arwert, F; de Koning, H; Joenje, H; Nieuwint, AW; Oostra, AB; Roozendaal, KJ, 1987) |
| "In order to develop the usefulness of Fanconi's anemia (FA) lymphoblast lines for biochemical and genetic studies, we have determined their sensitivity to a variety of DNA-damaging chemicals." | 1.26 | Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. ( Buchwald, M; Ishida, R, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (70.00) | 18.7374 |
| 1990's | 2 (5.00) | 18.2507 |
| 2000's | 2 (5.00) | 29.6817 |
| 2010's | 7 (17.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Farkas, G | 1 |
| Székely, G | 1 |
| Goda, V | 1 |
| Kállay, KM | 1 |
| Kocsis, ZS | 1 |
| Szakszon, K | 1 |
| Benyó, G | 1 |
| Erdélyi, D | 1 |
| Liptai, Z | 1 |
| Csordás, K | 1 |
| Kertész, G | 1 |
| Szegedi, I | 1 |
| Kriván, G | 1 |
| Takácsi-Nagy, Z | 1 |
| Polgár, C | 1 |
| Jurányi, Z | 1 |
| Dutta, A | 1 |
| De, R | 1 |
| Dolai, TK | 1 |
| Pal, P | 1 |
| Ghosh, S | 1 |
| Mitra, PK | 1 |
| Halder, A | 1 |
| Zhang, L | 1 |
| Liu, Q | 1 |
| Zou, Y | 1 |
| Liu, XM | 1 |
| Zhang, JY | 1 |
| Wang, SC | 1 |
| Chen, XJ | 1 |
| Guo, Y | 1 |
| Yang, WY | 1 |
| Ruan, M | 1 |
| Liu, TF | 1 |
| Liu, F | 1 |
| Cai, XJ | 1 |
| Chen, YM | 1 |
| Zhu, XF | 1 |
| Talmoudi, F | 2 |
| Kilani, O | 1 |
| Ayed, W | 1 |
| Ben Halim, N | 1 |
| Mellouli, F | 2 |
| Torjmane, L | 1 |
| Aissaoui, L | 2 |
| Ben Youssef, Y | 1 |
| Kammoun, L | 2 |
| Ben Othmane, T | 1 |
| Bejaoui, M | 2 |
| Ben Romdhane, N | 1 |
| Elloumi, M | 1 |
| Hadiji, S | 1 |
| Hentati, S | 1 |
| Chemkhi, I | 1 |
| Abidli, N | 1 |
| Guermani, H | 1 |
| Abdelhak, S | 2 |
| Amouri, A | 2 |
| Tummala, H | 1 |
| Kirwan, M | 1 |
| Walne, AJ | 1 |
| Hossain, U | 1 |
| Jackson, N | 1 |
| Pondarre, C | 1 |
| Plagnol, V | 1 |
| Vulliamy, T | 1 |
| Dokal, I | 1 |
| Fargo, JH | 1 |
| Rochowski, A | 1 |
| Giri, N | 1 |
| Savage, SA | 1 |
| Olson, SB | 1 |
| Alter, BP | 1 |
| Abo-Elwafa, HA | 1 |
| Attia, FM | 1 |
| Sharaf, AE | 1 |
| Benhalim, N | 1 |
| Torjemane, L | 1 |
| Ouederni, M | 1 |
| Lakhal, A | 1 |
| Othmen, TB | 1 |
| Meddeb, M | 1 |
| Dellagi, K | 1 |
| Hdiji, S | 1 |
| KUBOTA, J | 1 |
| Talwar, R | 1 |
| Choudhry, VP | 1 |
| Kucheria, K | 1 |
| Cohen, MM | 2 |
| Fruchtman, CE | 1 |
| Simpson, SJ | 2 |
| Martin, AO | 2 |
| Miura, K | 2 |
| Morimoto, K | 2 |
| Koizumi, A | 2 |
| Nagasawa, H | 1 |
| Little, JB | 1 |
| Zakrzewski, S | 2 |
| Koch, M | 1 |
| Sperling, K | 2 |
| Cervenka, J | 1 |
| Hirsch, BA | 1 |
| Kwee, ML | 1 |
| Poll, EH | 1 |
| van de Kamp, JJ | 1 |
| de Koning, H | 2 |
| Eriksson, AW | 1 |
| Joenje, H | 3 |
| Oostra, AB | 2 |
| Duckworth-Rysiecki, G | 4 |
| Hultén, M | 1 |
| Mann, J | 1 |
| Taylor, AM | 1 |
| Fujiwara, Y | 3 |
| Kano, Y | 2 |
| Yamamoto, Y | 1 |
| Kaneko, T | 1 |
| Iijima, K | 1 |
| Sato, M | 1 |
| Kaiser, TN | 1 |
| Lojewski, A | 1 |
| Dougherty, C | 1 |
| Juergens, L | 1 |
| Sahar, E | 1 |
| Latt, SA | 1 |
| Ishida, R | 1 |
| Buchwald, M | 4 |
| Honig, GR | 1 |
| Maurer, HS | 1 |
| Nicklas, JW | 1 |
| Rathbun, RK | 1 |
| Faulkner, GR | 1 |
| Ostroski, MH | 1 |
| Christianson, TA | 1 |
| Hughes, G | 1 |
| Jones, G | 1 |
| Cahn, R | 1 |
| Maziarz, R | 1 |
| Royle, G | 1 |
| Keeble, W | 1 |
| Heinrich, MC | 1 |
| Grompe, M | 1 |
| Tower, PA | 1 |
| Bagby, GC | 1 |
| Pagano, G | 1 |
| Korkina, LG | 1 |
| Rosselli, F | 1 |
| Moustacchi, E | 2 |
| Matsumoto, A | 1 |
| Vos, JM | 1 |
| Hanawalt, PC | 1 |
| Toji, L | 1 |
| Ng, J | 2 |
| Clarke, C | 2 |
| Nieuwint, AW | 1 |
| Arwert, F | 2 |
| Roozendaal, KJ | 1 |
| Claassen, E | 1 |
| Kortbeek, H | 1 |
| Zein, TA | 1 |
| Friedberg, N | 1 |
| Kim, H | 1 |
| Diatloff-Zito, C | 1 |
| Papadopoulo, D | 1 |
| Averbeck, D | 1 |
| German, J | 1 |
| Schonberg, S | 1 |
| Caskie, S | 1 |
| Warburton, D | 1 |
| Falk, C | 1 |
| Ray, JH | 1 |
| Rosendorff, J | 1 |
| Bernstein, R | 1 |
| Rudd, NL | 1 |
| Hoar, DI | 1 |
| Greentree, CL | 1 |
| Dimnik, LS | 1 |
| Hennig, UG | 1 |
| Cornish, K | 1 |
| Clarke, CA | 1 |
1 review available for mitomycin and Anemia, Aplastic
| Article | Year |
|---|---|
Prospects for nutritional interventions in the clinical management of Fanconi anemia.
Topics: Anemia, Aplastic; Antibiotics, Antineoplastic; Cell Transformation, Neoplastic; Disease Progression; | 2000 |
39 other studies available for mitomycin and Anemia, Aplastic
| Article | Year |
|---|---|
Chromosomal breakage tests in the differential diagnosis of Fanconi anemia and aplastic anemia.
Topics: Anemia, Aplastic; Bleomycin; Chromosome Breakage; Diagnosis, Differential; Fanconi Anemia; Humans; M | 2023 |
Incidence of Fanconi anaemia in phenotypically normal aplastic anaemia patients in West Bengal.
Topics: Anemia, Aplastic; Biomarkers; Child; Child, Preschool; Chromosome Aberrations; Fanconi Anemia; Femal | 2018 |
[Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia].
Topics: Adolescent; Anemia, Aplastic; Case-Control Studies; Child; Child, Preschool; Chromosomal Instability | 2013 |
Differentiation of Fanconi anemia and aplastic anemia using mitomycin C test in Tunisia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antibiotics, Antineoplastic; Child; Child, Preschool; Chromosom | 2013 |
ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function.
Topics: Acetylcysteine; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Cell Line, Tu | 2014 |
Comparison of chromosome breakage in non-mosaic and mosaic patients with Fanconi anemia, relatives, and patients with other inherited bone marrow failure syndromes.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Chil | 2014 |
The prognostic value of p53 mutation in pediatric marrow hypoplasia.
Topics: Adolescent; Anemia, Aplastic; Autoimmune Diseases; Bone Marrow Cells; Child; Child, Preschool; Chrom | 2011 |
Cytogenetic assessment of Fanconi anemia in children with aplastic anemia in Tunisia.
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Chromosomal Instability; Chromosome Breakage; | 2013 |
[TREATMENTS OF LEUKOPENIA ASSOCIATED WITH THE THERAPY OF MALIGNANT TUMORS].
Topics: Anemia; Anemia, Aplastic; Antineoplastic Agents; Bone Marrow Transplantation; Japan; Leukocyte Count | 1963 |
Differentiation of Fanconi anemia from idiopathic aplastic anemia by induced chromosomal breakage study using mitomycin-C (MMC).
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Child, Preschool; Chromosome Breakage; Diagnosis, Differ | 2004 |
The cytogenetic response of Fanconi's anemia lymphoblastoid cell lines to various clastogens.
Topics: Adult; Anemia, Aplastic; Ataxia Telangiectasia; Bleomycin; Cell Line; Child; Child, Preschool; Epoxy | 1982 |
Proliferative kinetics and mitomycin C-induced chromosome damage in Fanconi's anemia lymphocytes.
Topics: Adult; Anemia, Aplastic; Cell Division; Cells, Cultured; Child; Chromosome Aberrations; Crossing Ove | 1983 |
Suppression of cytotoxic effect of mitomycin-C by superoxide dismutase in Fanconi's anemia and dyskeratosis congenita fibroblasts.
Topics: Adolescent; Adult; Anemia, Aplastic; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Child; F | 1983 |
Complementation studies between Fanconi's anemia cells with different DNA repair characteristics.
Topics: Anemia, Aplastic; Cell Line; Cells, Cultured; Chromosome Aberrations; DNA Repair; Fanconi Anemia; Ge | 1983 |
Cytogenetic differentiation of Fanconi anemia, "idiopathic" aplastic anemia, and Fanconi anemia heterozygotes.
Topics: Adolescent; Adult; Anemia, Aplastic; Blood Preservation; Child; Child, Preschool; Chromosome Aberrat | 1983 |
Unusual response to bifunctional alkylating agents in a case of Fanconi anaemia.
Topics: Adolescent; Alkylating Agents; Anemia, Aplastic; Cells, Cultured; Child; Child, Preschool; Chromosom | 1983 |
Effect of oxygen tension on chromosomal aberrations in Fanconi anaemia.
Topics: Adult; Anemia, Aplastic; Cells, Cultured; Child; Chromosome Aberrations; Fanconi Anemia; Female; Hum | 1983 |
Clinical and cytogenetic diversity in Fanconi's anaemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Chromosome Aberrations; Chromosomes, Human; Diagnosis, D | 1984 |
DNA interstrand cross-linking, repair, and SCE mechanism in human cells in special reference to Fanconi anemia.
Topics: Anemia, Aplastic; Cell Survival; Cells, Cultured; Cross-Linking Reagents; DNA Repair; DNA Replicatio | 1984 |
Human health situation and chromosome alterations: sister chromatid exchange frequency in lymphocytes from passive smokers and patients with hereditary diseases.
Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Alzheimer Disease; Anemia, Aplastic; Cell Cycle; Cells, | 1984 |
Flow cytometric characterization of the response of Fanconi's anemia cells to mitomycin C treatment.
Topics: Alkylating Agents; Anemia, Aplastic; Cell Cycle; DNA Repair; DNA Replication; Fanconi Anemia; Flow C | 1982 |
Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Anemia, Aplastic; Antibiotics, Antineoplastic; Carcinog | 1982 |
Higher inductions of twin and single sister chromatid exchanges by cross-linking agents in Fanconi's anemia cells.
Topics: Anemia, Aplastic; Cells, Cultured; Cross-Linking Reagents; Crossing Over, Genetic; Fanconi Anemia; F | 1982 |
The identification of fanconi anemia genotypes by clastogenic stress.
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Chromosomes, Human; Epoxy Compounds; Fanconi | 1982 |
Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells.
Topics: Anemia, Aplastic; Antibiotics, Antineoplastic; Cell Cycle; DNA; DNA Repair; Fanconi Anemia; Fibrobla | 1982 |
Analysis of heterogeneity in Fanconi's anemia patients of different ethnic origin.
Topics: Adolescent; Anemia, Aplastic; Child; Chromosome Aberrations; Fanconi Anemia; Female; Humans; Hybrid | 1982 |
Inactivation of the Fanconi anemia group C gene augments interferon-gamma-induced apoptotic responses in hematopoietic cells.
Topics: Anemia, Aplastic; Animals; Annexin A5; Apoptosis; Cell Cycle Proteins; Cells, Cultured; DNA-Binding | 1997 |
Cocultivation of Fanconi anemia cells and of mouse lymphoma mutants leads to interspecies complementation of chromosomal hypersensitivity to DNA cross-linking agents.
Topics: Anemia, Aplastic; Animals; Cell Division; Cells, Cultured; Chromosome Aberrations; Fanconi Anemia; G | 1990 |
Repair analysis of mitomycin C-induced DNA crosslinking in ribosomal RNA genes in lymphoblastoid cells from Fanconi's anemia patients.
Topics: Anemia, Aplastic; Cell Survival; Cells, Cultured; Cross-Linking Reagents; DNA Damage; DNA Repair; DN | 1989 |
Characterization of a simian virus 40-transformed Fanconi anemia fibroblast cell line.
Topics: Anemia, Aplastic; Cell Cycle; Cell Line; Cell Survival; Cell Transformation, Viral; Chromosomes; Cro | 1986 |
Cytogenetic toxicity of paraquat and streptonigrin in Fanconi's anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Cells, Cultured; Child; Chromosome Aberrations; Fanconi Anemia; | 1987 |
Effects of mitomycin C on the rate of DNA synthesis in normal and Fanconi anaemia cells.
Topics: Anemia, Aplastic; Cell Line; DNA; Fanconi Anemia; Fibroblasts; Humans; Interphase; Mitomycin; Mitomy | 1986 |
Bone marrow suppression after intravesical mitomycin C treatment.
Topics: Aged; Anemia, Aplastic; Female; Humans; Mitomycin; Mitomycins; Postoperative Care; Urinary Bladder N | 1986 |
Abnormal response to DNA crosslinking agents of Fanconi anemia fibroblasts can be corrected by transfection with normal human DNA.
Topics: Anemia, Aplastic; Base Sequence; Cell Line; Cross-Linking Reagents; DNA; Drug Resistance; Fanconi An | 1986 |
A test for Fanconi's anemia.
Topics: Anemia, Aplastic; Blood Cells; Fanconi Anemia; Female; Humans; Lymphocytes; Male; Mitomycin; Mitomyc | 1987 |
Studies of gene transfer and reversion to mitomycin C resistance in Fanconi anemia cells.
Topics: Anemia, Aplastic; Cell Line; Cloning, Molecular; Cross-Linking Reagents; DNA Damage; Drug Resistance | 1987 |
Fanconi's anemia--chromosome breakage studies in homozygotes and heterozygotes.
Topics: Anemia, Aplastic; Cells, Cultured; Chromosome Aberrations; Epoxy Compounds; Fanconi Anemia; Heterozy | 1988 |
Micronucleus assay in human fibroblasts: a measure of spontaneous chromosomal instability and mutagen hypersensitivity.
Topics: Adult; Anemia, Aplastic; Ataxia Telangiectasia; Cell Nucleus; Cells, Cultured; Chromosomes; Cockayne | 1988 |
Identification of two complementation groups in Fanconi anemia.
Topics: Anemia, Aplastic; Cell Line; Chromosome Aberrations; Fanconi Anemia; Genetic Complementation Test; H | 1985 |