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mitomycin and Alopecia

mitomycin has been researched along with Alopecia in 11 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Alopecia: Absence of hair from areas where it is normally present.

Research Excerpts

ExcerptRelevanceReference
"In an attempt to examine the possibility of decreased toxicity in patients with advanced breast cancer who had not previously received chemotherapy, 33 women were given combination chemotherapy consisting of mitomycin C (10 mg/m2) every 6 weeks and mitoxantrone (6 mg/m2) every 3 weeks."9.06Mitomycin C and mitoxantrone chemotherapy for advanced breast cancer: efficacy with minimal gastrointestinal toxicity and alopecia. ( Begin, L; Margolese, R; Panasci, L; Pollak, M; Reinke, A; Shenouda, G, 1990)
"Since 2004, metastatic breast cancer patients pretreated with anthracyclines, taxanes, and capecitabine have been treated in our institution with a combination of mitomycin C, methotrexate, and VP-16 (VMM)."7.78Etoposide, mitomycin, and methotrexate combination in heavily treated breast cancer: a retrospective study. ( Aldabbagh, K; Fabbro, M; Jacot, W; Pouderoux, S; Poujol, S; Roca, L; Romieu, G, 2012)
"Twenty-six patients with advanced bronchogenic adenocarcinoma or large cell carcinoma were treated by combination chemotherapy consisting of Ftorafur, adriamycin and mitomycin C (FAM II)."7.67Ftorafur, adriamycin and mitomycin C (FAM II) for extensive bronchogenic adenocarcinoma and large cell carcinoma. ( Cruciani, AR; De Marinis, A; Nunziati, F; Portalone, L; Salvati, F, 1984)
"In 23 cases of primary advanced breast cancer, intra-arterial infusion chemotherapy of Adriamycin (ADR) and Mitomycin C (MMC), which were injected jointly or individually, was performed and its effects and side effects were studied."7.67[Intra-arterial infusion chemotherapy with anticancer agents for advanced breast cancer--effect and toxicity of mitomycin C and adriamycin]. ( Asaishi, K; Ebata, T; Hayasaka, H; Narimatsu, E; Okazaki, A; Okazaki, M; Okazaki, Y; Sato, N; Toda, K; Totsuka, M, 1985)
"In an attempt to examine the possibility of decreased toxicity in patients with advanced breast cancer who had not previously received chemotherapy, 33 women were given combination chemotherapy consisting of mitomycin C (10 mg/m2) every 6 weeks and mitoxantrone (6 mg/m2) every 3 weeks."5.06Mitomycin C and mitoxantrone chemotherapy for advanced breast cancer: efficacy with minimal gastrointestinal toxicity and alopecia. ( Begin, L; Margolese, R; Panasci, L; Pollak, M; Reinke, A; Shenouda, G, 1990)
"One hundred eighty-seven patients with histologically proven advanced pancreatic adenocarcinoma were randomly assigned to therapy with 5-fluorouracil (5-FU) alone, to the Mallinson regimen (combined and sequential 5-FU, cyclophosphamide, methotrexate, vincristine, and mitomycin C), or to combined 5-FU, doxorubicin, and cisplatin (FAP)."5.06A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin. ( Barlow, JF; Cullinan, S; Foley, JF; Kardinal, CG; Krook, JE; Moertel, CG; Norris, BD; Schutt, AJ; Tschetter, LK; Wieand, HS, 1990)
"Since 2004, metastatic breast cancer patients pretreated with anthracyclines, taxanes, and capecitabine have been treated in our institution with a combination of mitomycin C, methotrexate, and VP-16 (VMM)."3.78Etoposide, mitomycin, and methotrexate combination in heavily treated breast cancer: a retrospective study. ( Aldabbagh, K; Fabbro, M; Jacot, W; Pouderoux, S; Poujol, S; Roca, L; Romieu, G, 2012)
"Twenty-six patients with advanced bronchogenic adenocarcinoma or large cell carcinoma were treated by combination chemotherapy consisting of Ftorafur, adriamycin and mitomycin C (FAM II)."3.67Ftorafur, adriamycin and mitomycin C (FAM II) for extensive bronchogenic adenocarcinoma and large cell carcinoma. ( Cruciani, AR; De Marinis, A; Nunziati, F; Portalone, L; Salvati, F, 1984)
"In 23 cases of primary advanced breast cancer, intra-arterial infusion chemotherapy of Adriamycin (ADR) and Mitomycin C (MMC), which were injected jointly or individually, was performed and its effects and side effects were studied."3.67[Intra-arterial infusion chemotherapy with anticancer agents for advanced breast cancer--effect and toxicity of mitomycin C and adriamycin]. ( Asaishi, K; Ebata, T; Hayasaka, H; Narimatsu, E; Okazaki, A; Okazaki, M; Okazaki, Y; Sato, N; Toda, K; Totsuka, M, 1985)
" Our trial failed to demonstrate a significant improvement in response or survival when patients with metastatic NSCLC were treated, in addition to ifosfamide and mitomycin, by combination of moderate dosages of cisplatin and carboplatin instead of moderate dosage of cisplatin alone."2.69Phase III randomized trial comparing moderate-dose cisplatin to combined cisplatin and carboplatin in addition to mitomycin and ifosfamide in patients with stage IV non-small-cell lung cancer. ( Alexopoulos, CG; Baumöhl, J; Berghmans, T; Florin, MC; Klastersky, J; Koumakis, G; Lafitte, JJ; Mommen, P; Ninane, V; Paesmans, M; Schmerber, J; Sculier, JP; Thiriaux, J; Zacharias, C, 2000)
" No serious adverse effects were observed in any of the groups."2.66[Cooperative study of surgical adjuvant chemotherapy of colorectal cancer (first report): Investigation of background factors and adverse effects. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kasai, Y; Kikuchi, K; Komi, N; Kondo, T; Kunii, Y; Ogawa, N; Taguchi, T, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's5 (45.45)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aldabbagh, K1
Pouderoux, S1
Roca, L1
Poujol, S1
Fabbro, M1
Romieu, G1
Jacot, W1
Alexopoulos, A1
Rigatos, G1
Stavrinidis, E1
Stavrakakis, J1
Scartsilas, C1
Papacharalambous, A1
Salvati, F1
Cruciani, AR1
De Marinis, A1
Nunziati, F1
Portalone, L1
Xing, FY1
Liu, WH1
Dong, W1
Zhang, SL1
Gu, BW1
Okazaki, K1
Naito, H1
Inoue, T1
Wu, JT1
Tamura, S1
Ferrigno, D1
Buccheri, G1
Han, JY1
Kim, HK1
Choi, BG1
Moon, H1
Hong, YS1
Lee, KS1
Sculier, JP1
Lafitte, JJ1
Paesmans, M1
Thiriaux, J1
Alexopoulos, CG1
Baumöhl, J1
Schmerber, J1
Koumakis, G1
Florin, MC1
Zacharias, C1
Berghmans, T1
Mommen, P1
Ninane, V1
Klastersky, J1
Panasci, L1
Shenouda, G1
Begin, L1
Pollak, M1
Reinke, A1
Margolese, R1
Cullinan, S1
Moertel, CG1
Wieand, HS1
Schutt, AJ1
Krook, JE1
Foley, JF1
Norris, BD1
Kardinal, CG1
Tschetter, LK1
Barlow, JF1
Toda, K1
Asaishi, K1
Okazaki, A1
Okazaki, Y1
Okazaki, M1
Ebata, T1
Totsuka, M1
Hayasaka, H1
Sato, N1
Narimatsu, E1
Kunii, Y1
Kikuchi, K1
Kasai, Y1
Abe, O1
Kondo, T1
Taguchi, T1
Hattori, T1
Inokuchi, K1
Komi, N1
Ogawa, N1

Trials

6 trials available for mitomycin and Alopecia

ArticleYear
Is the MVP regimen less active than previously described? Results of a phase II study in advanced non-small cell lung cancer.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:4

    Topics: Adult; Aged; Alopecia; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Ph

1996
Quality of life (QOL) assessment of MIP (mitomycin, ifosfamide and cisplatin) chemotherapy in advanced non-small cell lung cancers (NSCLC).
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:12

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lun

1998
Phase III randomized trial comparing moderate-dose cisplatin to combined cisplatin and carboplatin in addition to mitomycin and ifosfamide in patients with stage IV non-small-cell lung cancer.
    British journal of cancer, 2000, Volume: 83, Issue:9

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-S

2000
Mitomycin C and mitoxantrone chemotherapy for advanced breast cancer: efficacy with minimal gastrointestinal toxicity and alopecia.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:6

    Topics: Alkylating Agents; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diges

1990
A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin.
    Cancer, 1990, May-15, Volume: 65, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Proto

1990
[Cooperative study of surgical adjuvant chemotherapy of colorectal cancer (first report): Investigation of background factors and adverse effects. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:2

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Fluorourac

1987

Other Studies

5 other studies available for mitomycin and Alopecia

ArticleYear
Etoposide, mitomycin, and methotrexate combination in heavily treated breast cancer: a retrospective study.
    Breast cancer (Tokyo, Japan), 2012, Volume: 19, Issue:1

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Fre

2012
Second and third line chemotherapy in advanced breast cancer.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Administration Sche

1989
Ftorafur, adriamycin and mitomycin C (FAM II) for extensive bronchogenic adenocarcinoma and large cell carcinoma.
    Japanese journal of clinical oncology, 1984, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Br

1984
[Alternative combination chemotherapy with mitomycin C, vincristine, methotrexate, 5-fluorouracil, cis-platinum and adriamycin for adenocarcinoma of the lung].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Do

1993
[Intra-arterial infusion chemotherapy with anticancer agents for advanced breast cancer--effect and toxicity of mitomycin C and adriamycin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:12

    Topics: Alopecia; Breast Neoplasms; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Female; Human

1985