mitomycin has been researched along with Allergic Encephalomyelitis in 5 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results found that Toxoplasma gondii infection in the brain increases SOCS3 expression and decreases the phosphorylation of STAT3, resulting in reducing IL-17A and IL-23, which suppress the differentiation and expansion of pathogenic Th17 cells, an important factor in MS development." | 1.62 | Chronic Toxoplasma gondii Infection Alleviates Experimental Autoimmune Encephalomyelitis by the Immune Regulation Inducing Reduction in IL-17A/Th17 Via Upregulation of SOCS3. ( Ham, DW; Kim, SG; Lee, SH; Seo, SH; Shin, EH; Shin, JH, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ham, DW | 1 |
| Kim, SG | 1 |
| Seo, SH | 1 |
| Shin, JH | 1 |
| Lee, SH | 1 |
| Shin, EH | 1 |
| Kleist, C | 2 |
| Mohr, E | 1 |
| Gaikwad, S | 1 |
| Dittmar, L | 1 |
| Kuerten, S | 1 |
| Platten, M | 1 |
| Mier, W | 1 |
| Schmitt, M | 1 |
| Opelz, G | 2 |
| Terness, P | 2 |
| Oelert, T | 1 |
| Ehser, S | 1 |
| Chuang, JJ | 1 |
| Lahdou, I | 1 |
| Velten, F | 1 |
| Hämmerling, GJ | 1 |
| Arnold, B | 1 |
| Mor, F | 1 |
| Cohen, IR | 1 |
| Mokhtarian, F | 1 |
| Shirazian, T | 1 |
| Batuman, O | 1 |
| Shi, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single-arm Phase-I Trial for the Determination of Safety and Feasibility of the Intravenous Administration of Mitomycin C-treated Donor Peripheral Blood Mononuclear Cells (MICs) for Individualized Immunosuppression in Living Donor Kidney Transplant Reci[NCT02560220] | Phase 1 | 14 participants (Actual) | Interventional | 2015-08-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for mitomycin and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Chronic Toxoplasma gondii Infection Alleviates Experimental Autoimmune Encephalomyelitis by the Immune Regulation Inducing Reduction in IL-17A/Th17 Via Upregulation of SOCS3.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Brain; Cisplatin; Enceph | 2021 |
Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis.
Topics: Animals; Apoptosis; Autoantigens; Cell Movement; Disease Models, Animal; Encephalomyelitis, Autoimmu | 2016 |
Mitomycin C-treated dendritic cells inactivate autoreactive T cells: toward the development of a tolerogenic vaccine in autoimmune diseases.
Topics: Animals; Autoimmune Diseases; Dendritic Cells; Encephalomyelitis, Autoimmune, Experimental; G1 Phase | 2008 |
IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis. Correlation with induction of Bcl-2.
Topics: Amino Acid Sequence; Animals; Antigens; Apoptosis; Base Sequence; Cells, Cultured; Cricetinae; Dexam | 1996 |
The effects of oral myelin basic protein and dexamethasone treatment on experimental autoimmune encephalomyelitis.
Topics: Administration, Oral; Animals; Antigens; Cells, Cultured; Combined Modality Therapy; Dexamethasone; | 1996 |