Page last updated: 2024-11-06

mitomycin and Airway Obstruction

mitomycin has been researched along with Airway Obstruction in 14 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

ExcerptRelevanceReference
"These results suggest that topical mitomycin is not effective for avoiding tracheal stenosis and may provoke the opposite effect if the dose is not carefully selected."7.74Effect of mitomycin in the surgical treatment of tracheal stenosis. ( González Bombardiere, S; Guilemany Toste, JM; Iñiguez-Cuadra, M; Iñiguez-Cuadra, R; Iñiguez-Sasso, R; Jofré Pavez, D; San Martín Prieto, J; Zúñiga Erranz, S, 2008)
"These results suggest that topical mitomycin is not effective for avoiding tracheal stenosis and may provoke the opposite effect if the dose is not carefully selected."3.74Effect of mitomycin in the surgical treatment of tracheal stenosis. ( González Bombardiere, S; Guilemany Toste, JM; Iñiguez-Cuadra, M; Iñiguez-Cuadra, R; Iñiguez-Sasso, R; Jofré Pavez, D; San Martín Prieto, J; Zúñiga Erranz, S, 2008)
"Acute airway obstruction may occur in MMC-treated rabbits with tracheal wounds."1.34Benefits and risks of mitomycin use in the traumatized tracheal mucosa. ( Kim, DH; Kim, KH; Park, CI; Rha, KS; Roh, JL; Sung, MW, 2007)
"There was a significant risk of acute airway obstruction from delayed wound healing in rabbits that received subglottic laser wounding and MMC treatment."1.33Can mitomycin C really prevent airway stenosis? ( Lee, YW; Park, CI; Roh, JL, 2006)
"Clinically, it appears as vesiculobullous lesions of the oral cavity and eyes, but other tissues such as the nasopharyngeal and laryngeal mucosa can also be affected."1.32Mucous membrane pemphigoid: nasal and laryngeal manifestations. ( Ali, I; Capper, JW; Martinez Devesa, P; Whiteside, OJ, 2003)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's10 (71.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, N1
Zhang, J1
Gnagi, SH1
White, DR1
Teo, FS1
Hsu, AA1
Thirugnanam, A1
Iñiguez-Cuadra, R1
San Martín Prieto, J1
Iñiguez-Cuadra, M1
Zúñiga Erranz, S1
Jofré Pavez, D1
González Bombardiere, S1
Guilemany Toste, JM1
Iñiguez-Sasso, R1
Bast, F1
Risteska, K1
Jovanovic, S1
Sedlmaier, B1
Veen, EJ1
Dikkers, FG1
Whiteside, OJ1
Martinez Devesa, P1
Ali, I1
Capper, JW1
Unal, M1
Hueman, EM1
Simpson, CB1
Roh, JL2
Lee, YW1
Park, CI2
Kim, DH1
Rha, KS1
Sung, MW1
Kim, KH1
Warner, D1
Brietzke, SE1
Correa, AJ1
Reinisch, L1
Sanders, DL1
Huang, S1
Deriso, W1
Duncavage, JA1
Garrett, CG1
Erard, AC1
Monnier, P1
Spiliopoulos, A1
Nicod, L1

Reviews

4 reviews available for mitomycin and Airway Obstruction

ArticleYear
[The mechanism and progress of topical application of mitomycin C as an adjunctive therapy for benign airway stenosis].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2013, Volume: 36, Issue:8

    Topics: Administration, Inhalation; Administration, Topical; Airway Obstruction; Animals; Bronchoscopy; Cica

2013
Beyond dilation: current concepts in endoscopic airway stenting and reconstruction.
    Current opinion in otolaryngology & head and neck surgery, 2016, Volume: 24, Issue:6

    Topics: Airway Obstruction; Endoscopy; Humans; Laryngoplasty; Laryngostenosis; Larynx; Mitomycin; Stents; Ti

2016
Topical use of MMC in the upper aerodigestive tract: a review on the side effects.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2010, Volume: 267, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Airway Obstruction; Animals; Child; Child, Preschool; Ci

2010
Mitomycin C and airway surgery: how well does it work?
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2008, Volume: 138, Issue:6

    Topics: Administration, Topical; Airway Obstruction; Animals; Cicatrix; Humans; Mitomycin; Nucleic Acid Synt

2008

Other Studies

10 other studies available for mitomycin and Airway Obstruction

ArticleYear
Recurrent foreign body granuloma with airway obstruction: is there a role for steroids?
    The Journal of thoracic and cardiovascular surgery, 2008, Volume: 136, Issue:1

    Topics: Airway Obstruction; Bronchoscopy; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Dysp

2008
Effect of mitomycin in the surgical treatment of tracheal stenosis.
    Archives of otolaryngology--head & neck surgery, 2008, Volume: 134, Issue:7

    Topics: Airway Obstruction; Anastomosis, Surgical; Animals; Antimitotic Agents; Biopsy; Bronchoscopy; Diseas

2008
[The topical application of mitomycin C in the treatment of scar formation and stenosis in hollow organs of the head and neck: a field report].
    Laryngo- rhino- otologie, 2009, Volume: 88, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Airway Obstruction; Antibiotics

2009
Mucous membrane pemphigoid: nasal and laryngeal manifestations.
    The Journal of laryngology and otology, 2003, Volume: 117, Issue:11

    Topics: Adjuvants, Immunologic; Adult; Airway Obstruction; Blister; Female; Hand Dermatoses; Humans; Immunos

2003
The successful management of congenital laryngeal web with endoscopic lysis and topical mitomycin-C.
    International journal of pediatric otorhinolaryngology, 2004, Volume: 68, Issue:2

    Topics: Airway Obstruction; Antibiotics, Antineoplastic; Humans; Infant; Laryngoscopy; Larynx; Male; Mitomyc

2004
Airway complications from topical mitomycin C.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2005, Volume: 133, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Airway Obstruction; Child; Chil

2005
Can mitomycin C really prevent airway stenosis?
    The Laryngoscope, 2006, Volume: 116, Issue:3

    Topics: Airway Obstruction; Animals; Disease Models, Animal; Female; Follow-Up Studies; Glottis; Mitomycin;

2006
Benefits and risks of mitomycin use in the traumatized tracheal mucosa.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2007, Volume: 136, Issue:3

    Topics: Airway Obstruction; Animals; Antibiotics, Antineoplastic; Cause of Death; Cicatrix; Disease Models,

2007
Inhibition of subglottic stenosis with mitomycin-C in the canine model.
    The Annals of otology, rhinology, and laryngology, 1999, Volume: 108, Issue:11 Pt 1

    Topics: Administration, Topical; Airway Obstruction; Animals; Dilatation; Disease Models, Animal; Dogs; Lary

1999
Mitomycin C for control of recurrent bronchial stenosis: a case report.
    Chest, 2001, Volume: 120, Issue:6

    Topics: Administration, Topical; Adult; Airway Obstruction; Bronchi; Bronchial Diseases; Cystic Fibrosis; Di

2001