mitomycin has been researched along with Aging in 19 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There was a significant correlation between the area under the time versus concentration curve (AUC) of MMC and the age of patients (r = 0." | 5.28 | Pharmacokinetic study of mitomycin C with emphasis on the influence of aging. ( Karato, A; Miya, T; Saijo, N; Sasaki, Y, 1992) |
| " There was significant correlation between the age of the patients and U-Pt pharmacokinetic parameters such as the area under the plasma concentration versus time curve (AUC), total clearance (Cl), and peak plasma concentration (Cmax) as well as the AUC of T-Pt (P < 0." | 1.29 | The influence of ageing on cisplatin pharmacokinetics in lung cancer patients with normal organ function. ( Ando, M; Eguchi, K; Katsumata, N; Maeda, M; Ohe, Y; Oshita, F; Shinkai, T; Shiraishi, J; Tamura, T; Yamamoto, N, 1995) |
| ") were injected with MMC at a dosage of 3 to 5 mg/kg to inhibit the bone marrow, thus creating a mouse model with reduced immunopotential." | 1.29 | [The effect of herbal medicines on the immunodeficient animals by injecting cancer chemotherapeutic agent-special reference to age related recovery of the function]. ( Komatsu, Y; Li, AL; Nakashima, K; Nakatani, F; Ono, Y; Yamaguchi, N, 1996) |
| " There was a significant correlation between the area under the time versus concentration curve (AUC) of MMC and the age of patients (r = 0." | 1.28 | Pharmacokinetic study of mitomycin C with emphasis on the influence of aging. ( Karato, A; Miya, T; Saijo, N; Sasaki, Y, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 9 (47.37) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, S | 1 |
| Yu, KR | 1 |
| Ryu, YS | 1 |
| Oh, YS | 1 |
| Hong, IS | 1 |
| Kim, HS | 1 |
| Lee, JY | 1 |
| Kim, S | 1 |
| Seo, KW | 1 |
| Kang, KS | 1 |
| Orsburn, B | 1 |
| Escudero, B | 1 |
| Prakash, M | 1 |
| Gesheva, S | 1 |
| Liu, G | 1 |
| Huso, DL | 1 |
| Franco, S | 1 |
| Klajman, A | 1 |
| Drucker, I | 1 |
| Manor, Y | 1 |
| Lil'p, IG | 1 |
| Musilová, J | 1 |
| Michalová, K | 1 |
| Pacovský, V | 1 |
| Schneider, EL | 1 |
| Lewis, J | 1 |
| Yamamoto, N | 1 |
| Tamura, T | 2 |
| Maeda, M | 1 |
| Ando, M | 1 |
| Shinkai, T | 2 |
| Eguchi, K | 2 |
| Ohe, Y | 2 |
| Oshita, F | 2 |
| Shiraishi, J | 1 |
| Katsumata, N | 1 |
| Vabnick, I | 1 |
| Novaković, SD | 1 |
| Levinson, SR | 1 |
| Schachner, M | 1 |
| Shrager, P | 1 |
| Li, AL | 1 |
| Komatsu, Y | 1 |
| Ono, Y | 1 |
| Nakatani, F | 1 |
| Nakashima, K | 1 |
| Yamaguchi, N | 1 |
| Scarfí, MR | 1 |
| Prisco, F | 1 |
| Bersani, F | 1 |
| Lioi, MB | 1 |
| Zeni, O | 1 |
| Di Pietro, R | 1 |
| Franceschi, C | 1 |
| Motta, M | 1 |
| Iafusco, D | 1 |
| Stoppoloni, G | 1 |
| Verhagen, H | 1 |
| Rauma, AL | 1 |
| Törrönen, R | 1 |
| de Vogel, N | 1 |
| Bruijntjes-Rozier, GC | 1 |
| Drevo, MA | 1 |
| Bogaards, JJ | 1 |
| Mykkänen, H | 1 |
| Dass, SB | 1 |
| Ali, SF | 1 |
| Heflich, RH | 1 |
| Casciano, DA | 1 |
| Miya, T | 2 |
| Sasaki, Y | 2 |
| Karato, A | 1 |
| Saijo, N | 2 |
| Kojima, A | 1 |
| Rockwell, S | 1 |
| Hughes, CS | 1 |
| Kennedy, KA | 1 |
| Nagaya, T | 1 |
| Toriumi, H | 1 |
| Abe, F | 1 |
| Hayashi, M | 1 |
| Horinishi, H | 1 |
| Matsuda, A | 1 |
| Ishizuka, M | 1 |
| Umezawa, H | 1 |
| Nagai, K | 1 |
| Suda, T | 1 |
19 other studies available for mitomycin and Aging
| Article | Year |
|---|---|
miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18.
Topics: Aging; Animals; Cells, Cultured; Cellular Senescence; Gene Expression Regulation; Humans; Mesenchyma | 2014 |
Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Topics: Aging; Animals; B-Lymphocytes; Chromosomal Proteins, Non-Histone; DNA; DNA Breaks, Double-Stranded; | 2010 |
Autologous mixed lymphocyte reaction in man: further characterization of responding cells.
Topics: Adult; Aged; Aging; B-Lymphocytes; Humans; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Ly | 1983 |
[Effect of mouse age and genotype on the frequency of sister chromatid exchange in bone marrow cells].
Topics: Aging; Animals; Bone Marrow; Bromodeoxyuridine; Chromosome Aberrations; Crossing Over, Genetic; Geno | 1984 |
Induction of sister chromatid exchanges by mitomycin C in lymphocytes of young and old human donors.
Topics: Adolescent; Adult; Aged; Aging; Antibiotics, Antineoplastic; Cell Division; Humans; Kinetics; Lympho | 1984 |
Aging and sister chromatid exchange. VIII. Effect of the aging environment on sister chromatid exchange induction and cell cycle kinetics in Ehrlich ascites tumor cells. A brief note.
Topics: Aging; Animals; Bone Marrow Cells; Carcinoma, Ehrlich Tumor; Cell Division; Crossing Over, Genetic; | 1981 |
The influence of ageing on cisplatin pharmacokinetics in lung cancer patients with normal organ function.
Topics: Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Antineoplastic Combined Chemotherapy Pr | 1995 |
The clustering of axonal sodium channels during development of the peripheral nervous system.
Topics: Aging; Animals; Animals, Newborn; Axons; Cell Division; Mitomycin; Myelin-Associated Glycoprotein; P | 1996 |
[The effect of herbal medicines on the immunodeficient animals by injecting cancer chemotherapeutic agent-special reference to age related recovery of the function].
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Administration, Oral; Aging; Animals; An | 1996 |
Spontaneous and mitomycin-C-induced micronuclei in lymphocytes from subjects affected by Turner's syndrome.
Topics: Adolescent; Adult; Aging; Cell Division; Child; Child, Preschool; Chromosome Aberrations; Female; Hu | 1996 |
Effect of a vegan diet on biomarkers of chemoprevention in females.
Topics: Adult; Aged; Aging; Antibiotics, Antineoplastic; Cells, Cultured; Chemoprevention; Cross-Sectional S | 1996 |
Frequency of spontaneous and induced micronuclei in the peripheral blood of aging mice.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Micronuclei, Chrom | 1997 |
Pharmacokinetic study of mitomycin C with emphasis on the influence of aging.
Topics: Adult; Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; | 1992 |
[The relation between myelotoxicity and performance status or aging in chemotherapy of non-small cell lung cancer].
Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcino | 1991 |
Effect of host age on microenvironmental heterogeneity and efficacy of combined modality therapy in solid tumors.
Topics: Acid-Base Equilibrium; Aging; Animals; Antineoplastic Agents; Combined Modality Therapy; Female; Lis | 1991 |
Spontaneous and induced sister chromatid exchanges in lymphocytes of healthy persons.
Topics: Adult; Aging; Humans; Lymphocytes; Male; Middle Aged; Mitomycin; Mitomycins; Mutagens; Sister Chroma | 1986 |
Enhancement of graft-versus-host reaction and delayed cutaneous hypersensitivity in mice by ubenimex.
Topics: Adjuvants, Immunologic; Aging; Animals; Dose-Response Relationship, Drug; Graft vs Host Reaction; Hy | 1986 |
[Immunoregulative effects of homocarnosine and gamma-aminobuthyric acid].
Topics: Aging; Animals; Antibody Formation; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Homeostasis; Imm | 1986 |
Age and dose of chemotherapy as major prognostic factors in a trial of adjuvant therapy of osteosarcoma combining two alternating drug combinations and early prophylactic lung irradiation. French Bone Tumor Study Group.
Topics: Adolescent; Adult; Aging; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Com | 1988 |