mitomycin has been researched along with Adverse Drug Event in 11 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this phase II study was to investigate the tolerance and efficacy of a second-line irinotecan/mitomycin C combination in patients with advanced gastric or colorectal cancer, pretreated with 5-fluorouracil." | 5.10 | Phase II study of irinotecan and mitomycin C in 5-fluorouracil-pretreated patients with advanced colorectal and gastric cancer. ( Bamias, A; Papamichael, D; Pavlidis, N; Syrigos, K, 2003) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Mathes, J | 1 |
| Todenhöfer, T | 1 |
| Miranda, MB | 1 |
| Hartmann, JT | 1 |
| Al-Batran, SE | 1 |
| Kripp, M | 1 |
| Gencer, D | 1 |
| Hochhaus, A | 1 |
| Hofheinz, RD | 1 |
| Merx, K | 1 |
| McHaffie, DR | 1 |
| Kozak, KR | 1 |
| Kislukhin, G | 1 |
| Murphy, ML | 1 |
| Jafari, M | 1 |
| Long, AD | 1 |
| Bamias, A | 1 |
| Papamichael, D | 1 |
| Syrigos, K | 1 |
| Pavlidis, N | 1 |
| Shukla, SJ | 1 |
| Dolan, ME | 1 |
| Windschall, A | 1 |
| Ott, OJ | 1 |
| Sauer, R | 1 |
| Strnad, V | 1 |
| Fillastre, JP | 1 |
| Méry, JP | 1 |
| Druet, P | 1 |
2 reviews available for mitomycin and Adverse Drug Event
| Article | Year |
|---|---|
Use of CEPH and non-CEPH lymphoblast cell lines in pharmacogenetic studies.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Cell Line, Transformed; Cell Transfor | 2005 |
[Drug-induced glomerular nephropathies].
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Daunorubicin; Disease Models, Animal; Doxorubici | 1983 |
2 trials available for mitomycin and Adverse Drug Event
| Article | Year |
|---|---|
Mitomycin C and capecitabine in pretreated patients with metastatic gastric cancer: a multicenter phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycyti | 2014 |
Phase II study of irinotecan and mitomycin C in 5-fluorouracil-pretreated patients with advanced colorectal and gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chi-Squar | 2003 |
7 other studies available for mitomycin and Adverse Drug Event
| Article | Year |
|---|---|
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Managing Toxicity of Intravesical Therapy.
Topics: Adjuvants, Immunologic; Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Drug-Relat | 2018 |
Optimizing outcomes of chemoradiation in the management of squamous cell carcinoma of the anal canal.
Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin; | 2010 |
Chemotherapy-induced toxicity is highly heritable in Drosophila melanogaster.
Topics: Animals; Carboplatin; Deoxycytidine; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug | 2012 |
Radiation therapy and simultaneous chemotherapy for recurrent cervical carcinoma.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; An | 2005 |