mitomycin has been researched along with Adhesions, Tissue in 60 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the efficacy of mitomycin C in reducing postoperative adhesions following strabismus surgery." | 9.11 | Evaluation of mitomycin C in reducing postoperative adhesions in strabismus surgery. ( Chen, PL; Chen, WY; Lu, DW, 2005) |
| "A prospective randomized study to compare the effectiveness of pleurodesis by two new sclerosing agents: OK-432 and mitomycin C were conducted in 53 patients with malignant pleural effusion caused by lung cancer." | 9.07 | Comparison of OK-432 and mitomycin C pleurodesis for malignant pleural effusion caused by lung cancer. A randomized trial. ( Chang, DB; Kuo, SH; Lee, LN; Luh, KT; Yang, PC; Yu, CJ, 1992) |
| " The purpose of this study was to investigate the effect of mitomycin C on reducing endometrial fibrosis for IUA." | 7.96 | The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion. ( Shen, X; Sun, C; Wang, W; Xu, F; Xu, X; Zheng, J, 2020) |
| "The authors conducted a study to determine the effectiveness of mitomycin C (MMC) in preventing epidural fibrosis in rats which underwent craniectomy." | 7.75 | The effect of mitomycin C as fibrosis preventive agent during craniectomies. ( Cemil, B; Cevirgen, B; Gurcay, AG; Kaptanoglu, E; Kaymaz, F; Tekdemir, I; Tun, K, 2009) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 7.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "There was intensive epineural scar formation in the control group." | 5.43 | Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin. ( Ilbay, G; Ilbay, K; Vural, E; Yilmaz, M, 2016) |
| "Epidural fibrosis was evaluated histologically." | 5.32 | Mitomycin C in preventing spinal epidural fibrosis in a laminectomy model in rats. ( Ebel, H; Ernestus, RI; Klug, N; Lee, JY; Stenzel, W; Wedekind, C, 2004) |
| "The rates of recurrence (5% to 9%) and complications in eyes that had undergone excision and mitomycin C instillation were less than those in eyes that had had excision only." | 5.28 | Postoperative instillation of mitomycin C in the treatment of recurrent pterygium. ( Hayasaka, S; Noda, S; Setogawa, T; Yamamoto, Y, 1989) |
| "At the end of endoscopic surgery for chronic rhinosinusitis and four weeks postoperatively 30 patients received a pledget soaked with 1 ml of mitomycin C (0." | 5.13 | Intra- and postoperative application of Mitomycin C in the middle meatus reduces adhesions and antrostomy stenosis after FESS. ( Constantinidis, J; Konstantinidis, I; Triaridis, S; Tsakiropoulou, E; Vital, I; Vital, V, 2008) |
| "The aim of this study was to evaluate the efficacy of mitomycin C in reducing postoperative adhesions following strabismus surgery." | 5.11 | Evaluation of mitomycin C in reducing postoperative adhesions in strabismus surgery. ( Chen, PL; Chen, WY; Lu, DW, 2005) |
| "A prospective randomized study to compare the effectiveness of pleurodesis by two new sclerosing agents: OK-432 and mitomycin C were conducted in 53 patients with malignant pleural effusion caused by lung cancer." | 5.07 | Comparison of OK-432 and mitomycin C pleurodesis for malignant pleural effusion caused by lung cancer. A randomized trial. ( Chang, DB; Kuo, SH; Lee, LN; Luh, KT; Yang, PC; Yu, CJ, 1992) |
| " The purpose of this study was to investigate the effect of mitomycin C on reducing endometrial fibrosis for IUA." | 3.96 | The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion. ( Shen, X; Sun, C; Wang, W; Xu, F; Xu, X; Zheng, J, 2020) |
| "The authors conducted a study to determine the effectiveness of mitomycin C (MMC) in preventing epidural fibrosis in rats which underwent craniectomy." | 3.75 | The effect of mitomycin C as fibrosis preventive agent during craniectomies. ( Cemil, B; Cevirgen, B; Gurcay, AG; Kaptanoglu, E; Kaymaz, F; Tekdemir, I; Tun, K, 2009) |
| "To evaluate influence of mitomycin C on fibrosis in temporomandibular joints of rabbits with mandibular traction." | 3.73 | Mitomycin C effect on fibrous adhesions of rabbit temporomandibular joint. ( Aydin, E; Ozdemir, BH; Uckan, S; Uyar, P, 2005) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 3.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "Velopharyngeal stenosis (VS) is a rare devastating complication of adenotonsillectomy that causes obstructive sleep apnea (OSA)." | 2.90 | Treatment of post-adenotonsillectomy velopharyngeal stenosis with bivalved uvular flaps. ( Abdel-Aziz, M; Abdel-Wahid, A; El-Fouly, M; El-Tahan, AR; Kamel, A, 2019) |
| "Management of bilateral congenital choanal atresia is better by endoscopic transnasal approach with application of mitomycin-c." | 2.78 | Management of bilateral congenital choanal atresia. ( Hadi, HI; Homaira, R; Sattar, MA; Sultana, T, 2013) |
| "Mitomycin C (MMC) is an antineoplastic agent that has been shown to decrease scar tissue after ophthalmologic surgery." | 2.70 | Mitomycin C for the prevention of adhesion formation after endoscopic sinus surgery: a randomized, controlled study. ( Chung, JH; Cosenza, MJ; Metson, RB; Rahbar, R, 2002) |
| "Mitomycin C benefits were found in subgroups of age ≤ 40 years (RR = 0." | 2.49 | Efficacy of Mitomycin C for postoperative endoscopic sinus surgery: a systematic review and meta-analysis. ( Attia, J; McEvoy, M; Numthavaj, P; Roongpuvapaht, B; Tanjararak, K; Thakkinstian, A, 2013) |
| "Mitomycin C has been used successfully in various ophthalmologic and, more recently, otolaryngologic procedures." | 2.44 | Mitomycin C and endoscopic sinus surgery: where are we? ( Anand, VK; Brown, SM; Tabaee, A, 2007) |
| "Mitomycin C (MMC) has been demonstrated to have significant inhibitory effects on epidural scar." | 1.46 | MMC controlled-release membranes attenuate epidural scar formation in rat models after laminectomy. ( Cao, X; Geng, D; Jiang, L; Liu, J; Qin, J; Shen, X; Wang, B; Wu, T; Xie, H; Yu, C; Yuan, T, 2017) |
| "There was intensive epineural scar formation in the control group." | 1.43 | Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin. ( Ilbay, G; Ilbay, K; Vural, E; Yilmaz, M, 2016) |
| "Mitomycin-C has been in clinical use primarily as a chemotherapeutic agent and is well known for antifibrotic properties." | 1.39 | The effect of mitomycin-C in reducing pericardial adhesion after cardiac surgery in rabbits. ( Akkaya, IO; Aksoy, ON; Alpay, MF; Bayrak, R; Cakir, O; Colak, N; Nazli, Y; Tasoglu, I, 2013) |
| "Mitomycin C was not effective in preventing middle meatus synechia, but reduced the probability of total synechia formation." | 1.38 | The use of Mitomycin-C to reduce synechia in middle meatus in sinus surgery: preliminary results. ( Gregório, LC; Yamaoka, WY, 2012) |
| "Mitomycin C (MMC) could also reduce the scar formation after surgery, but cytotoxicity and the administrative pathway prevent its application." | 1.36 | Mitomycin C-polyethylene glycol controlled-release film inhibits collagen secretion and induces apoptosis of fibroblasts in the early wound of a postlaminectomy rat model. ( Cao, X; Liu, J; Ni, B; Yang, J; Zhou, W; Zhu, L, 2010) |
| "Mitomycin C was equally effective as pimecrolimus in reducing epidural fibrosis and dural adherence in this study." | 1.35 | Use of pimecrolimus to prevent epidural fibrosis in a postlaminectomy rat model. ( Cemil, B; Cevirgen, B; Comert, A; Kaptanoglu, E; Kaymaz, F; Tekdemir, I; Tun, K, 2009) |
| "Hydroxyproline (HP) levels were significantly higher in control group than all other groups (P < 0." | 1.34 | Antiadhesive effects of mitomycin C and streptopeptidase A in rats with intraperitoneal adhesions. ( Ariturk, E; Bernay, F; Bicakci, U; Kilicoglu-Aydin, B; Rizalar, R; Tander, B, 2007) |
| "Epidural fibrosis was evaluated histologically." | 1.32 | Mitomycin C in preventing spinal epidural fibrosis in a laminectomy model in rats. ( Ebel, H; Ernestus, RI; Klug, N; Lee, JY; Stenzel, W; Wedekind, C, 2004) |
| " In this study, an alternative approach was proposed and pharmaco-therapeutic agent delivery systems which will supply the suitable dosage of the agent for a certain time period were designed to solve those problems." | 1.32 | Bioadhesive drug carriers for postoperative chemotherapy in bladder cancer. ( Denkbaş, EB; Eroğlu, M; Ozdemir, N; Oztürk, E, 2004) |
| "Mitomycin C (MMC) is a cytotoxic agent that alkylates and crosslinks DNA and also inhibits fibroblast proliferation up to a few weeks." | 1.31 | An experimental study evaluating the effect of Mitomycin C on the prevention of postoperative intraabdominal adhesions. ( Alponat, A; Cubukçu, A; Erçin, C; Gönüllü, NN; Ozkan, S, 2001) |
| "The rates of recurrence (5% to 9%) and complications in eyes that had undergone excision and mitomycin C instillation were less than those in eyes that had had excision only." | 1.28 | Postoperative instillation of mitomycin C in the treatment of recurrent pterygium. ( Hayasaka, S; Noda, S; Setogawa, T; Yamamoto, Y, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.67) | 18.7374 |
| 1990's | 5 (8.33) | 18.2507 |
| 2000's | 29 (48.33) | 29.6817 |
| 2010's | 21 (35.00) | 24.3611 |
| 2020's | 4 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, H | 1 |
| Wang, S | 1 |
| Sun, Y | 4 |
| Wang, J | 3 |
| Sultana, T | 2 |
| Van Hai, H | 1 |
| Park, M | 1 |
| Lee, SY | 1 |
| Lee, BT | 1 |
| Xu, F | 1 |
| Shen, X | 2 |
| Sun, C | 1 |
| Xu, X | 1 |
| Wang, W | 1 |
| Zheng, J | 1 |
| Xie, H | 1 |
| Wang, B | 1 |
| Qin, J | 1 |
| Jiang, L | 1 |
| Yu, C | 1 |
| Geng, D | 1 |
| Yuan, T | 1 |
| Wu, T | 1 |
| Cao, X | 2 |
| Liu, J | 2 |
| Shi, R | 1 |
| Huang, Y | 1 |
| Zhang, J | 1 |
| Wu, C | 1 |
| Gong, M | 1 |
| Tian, W | 1 |
| Zhang, L | 1 |
| Abdel-Aziz, M | 1 |
| El-Tahan, AR | 1 |
| El-Fouly, M | 1 |
| Kamel, A | 1 |
| Abdel-Wahid, A | 1 |
| Sattar, MA | 1 |
| Hadi, HI | 1 |
| Homaira, R | 1 |
| Numthavaj, P | 1 |
| Tanjararak, K | 1 |
| Roongpuvapaht, B | 1 |
| McEvoy, M | 1 |
| Attia, J | 1 |
| Thakkinstian, A | 1 |
| Orhan, A | 1 |
| Görmüş, N | 1 |
| Toy, H | 1 |
| Görmüş, IS | 1 |
| Çağlayan, O | 1 |
| Tanyeli, Ö | 1 |
| Konstantinidis, I | 2 |
| Chatziavramidis, A | 1 |
| Constantinidis, J | 2 |
| Zhao, X | 1 |
| Jiang, S | 1 |
| Liu, S | 1 |
| Chen, S | 1 |
| Lin, ZY | 1 |
| Pan, G | 1 |
| He, F | 1 |
| Li, F | 1 |
| Fan, C | 1 |
| Cui, W | 1 |
| Vural, E | 1 |
| Yilmaz, M | 1 |
| Ilbay, K | 1 |
| Ilbay, G | 1 |
| Urkan, M | 1 |
| Özerhan, İH | 1 |
| Ünlü, A | 1 |
| Can, MF | 1 |
| Öztürk, E | 2 |
| Günal, A | 1 |
| Yağcı, G | 1 |
| Tsakiropoulou, E | 1 |
| Vital, I | 1 |
| Triaridis, S | 1 |
| Vital, V | 1 |
| Zhang, Y | 2 |
| Yin, QS | 1 |
| Zhou, CS | 1 |
| Jiang, GB | 1 |
| Bajaj, Y | 1 |
| Sethi, N | 1 |
| Shayah, A | 1 |
| Coatesworth, A | 1 |
| Okuda, T | 1 |
| Higashide, T | 1 |
| Fukuhira, Y | 1 |
| Sumi, Y | 1 |
| Shimomura, M | 1 |
| Sugiyama, K | 1 |
| Kim, HY | 1 |
| Dhong, HJ | 1 |
| Min, JY | 1 |
| Jung, YG | 1 |
| Park, SH | 1 |
| Chung, SK | 1 |
| Cemil, B | 3 |
| Tun, K | 2 |
| Kaptanoglu, E | 2 |
| Cevirgen, B | 2 |
| Gurcay, AG | 1 |
| Kaymaz, F | 2 |
| Tekdemir, I | 2 |
| Comert, A | 1 |
| Fonseca, VR | 1 |
| Malafaia, O | 1 |
| Ribas Filho, JM | 1 |
| Nassif, PA | 1 |
| Czeczko, NG | 1 |
| Marcondes, CA | 1 |
| Nascimento, MM | 1 |
| Ni, B | 1 |
| Zhu, L | 1 |
| Yang, J | 2 |
| Zhou, W | 1 |
| Rabb, CH | 1 |
| Kocaoglu, B | 2 |
| Akgun, U | 1 |
| Nalbantoglu, U | 2 |
| Poyanlı, O | 1 |
| Karahan, M | 2 |
| Agir, I | 1 |
| Türkmen, M | 1 |
| Yan, L | 2 |
| Dai, S | 2 |
| Feng, X | 2 |
| Jiang, B | 2 |
| Wang, Q | 2 |
| Yu, T | 2 |
| Shi, X | 1 |
| Baradaranfar, MH | 1 |
| Khadem, J | 1 |
| Taghipoor Zahir, S | 1 |
| Kouhi, A | 1 |
| Dadgarnia, MH | 1 |
| Baradarnfar, A | 1 |
| Venkatraman, V | 1 |
| Balasubramanian, D | 1 |
| Gopalakrishnan, S | 1 |
| Saxena, SK | 1 |
| Shanmugasundaram, N | 1 |
| Wang, D | 1 |
| Gu, J | 1 |
| Hu, H | 1 |
| Yin, B | 1 |
| Lv, G | 1 |
| Colak, N | 1 |
| Nazli, Y | 1 |
| Tasoglu, I | 1 |
| Bayrak, R | 1 |
| Alpay, MF | 1 |
| Aksoy, ON | 1 |
| Akkaya, IO | 1 |
| Cakir, O | 1 |
| Carifi, M | 1 |
| Yamaoka, WY | 1 |
| Gregório, LC | 1 |
| Lee, JY | 3 |
| Stenzel, W | 3 |
| Ebel, H | 2 |
| Wedekind, C | 1 |
| Ernestus, RI | 3 |
| Klug, N | 3 |
| Eşme, A | 1 |
| Yildirim, C | 1 |
| Tatlipinar, S | 1 |
| Düzcan, E | 1 |
| Yaylali, V | 1 |
| Ozden, S | 1 |
| Eroğlu, M | 1 |
| Ozdemir, N | 1 |
| Denkbaş, EB | 1 |
| Liu, Y | 1 |
| Li, H | 1 |
| Shu, XZ | 1 |
| Gray, SD | 1 |
| Prestwich, GD | 1 |
| Yao, YF | 1 |
| Qiu, WY | 1 |
| Zhang, YM | 1 |
| Tseng, SC | 1 |
| Chen, PL | 1 |
| Chen, WY | 1 |
| Lu, DW | 1 |
| Aydin, E | 1 |
| Uckan, S | 1 |
| Ozdemir, BH | 1 |
| Uyar, P | 1 |
| Battelino, S | 1 |
| Hocevar-Boltezar, I | 1 |
| Zargi, M | 1 |
| Löhr, M | 2 |
| Stützer, H | 2 |
| Impekoven, P | 1 |
| Theisohn, M | 1 |
| Reithmeier, T | 1 |
| Gupta, M | 1 |
| Motwani, G | 1 |
| Tabaee, A | 1 |
| Brown, SM | 1 |
| Anand, VK | 1 |
| Scheithauer, MO | 1 |
| Riechelmann, H | 1 |
| Tander, B | 1 |
| Bicakci, U | 1 |
| Kilicoglu-Aydin, B | 1 |
| Ariturk, E | 1 |
| Rizalar, R | 1 |
| Bernay, F | 1 |
| Wang, LX | 1 |
| Wang, L | 1 |
| Sun, SX | 1 |
| Cao, XJ | 1 |
| Wang, P | 1 |
| Feng, L | 1 |
| Kurt, G | 1 |
| Aytar, MH | 1 |
| Doğulu, F | 1 |
| Erdem, O | 1 |
| Baykaner, MK | 1 |
| Ceviker, N | 1 |
| Adachi, W | 1 |
| Koike, S | 1 |
| Rafique, M | 1 |
| Kajikawa, S | 1 |
| Kaneko, G | 1 |
| Kuroda, T | 1 |
| Iida, F | 1 |
| Ishii, K | 1 |
| Oh, SO | 1 |
| Chang, BL | 2 |
| Lee, J | 1 |
| Matsuoka, H | 1 |
| Yano, K | 1 |
| Katsuta, Y | 1 |
| Morita, M | 1 |
| Kounoe, S | 1 |
| Seo, Y | 1 |
| Saito, T | 1 |
| Tomoda, H | 1 |
| Oh, SY | 1 |
| Park, DW | 1 |
| Jansen, M | 1 |
| Fass, J | 1 |
| Langejürgen, E | 1 |
| Forsch, S | 1 |
| Tietze, L | 1 |
| Schumpelick, V | 1 |
| Cubukçu, A | 2 |
| Alponat, A | 2 |
| Gönüllü, NN | 2 |
| Ozkan, S | 1 |
| Erçin, C | 1 |
| Paridaens, D | 1 |
| Beekhuis, H | 1 |
| van Den Bosch, W | 1 |
| Remeyer, L | 1 |
| Melles, G | 1 |
| Doe, EA | 1 |
| Budenz, DL | 1 |
| Gedde, SJ | 1 |
| Imami, NR | 1 |
| Chung, JH | 1 |
| Cosenza, MJ | 1 |
| Rahbar, R | 1 |
| Metson, RB | 1 |
| Luh, KT | 1 |
| Yang, PC | 1 |
| Kuo, SH | 1 |
| Chang, DB | 1 |
| Yu, CJ | 1 |
| Lee, LN | 1 |
| Hayasaka, S | 1 |
| Noda, S | 1 |
| Yamamoto, Y | 1 |
| Setogawa, T | 1 |
3 reviews available for mitomycin and Adhesions, Tissue
| Article | Year |
|---|---|
Efficacy of Mitomycin C for postoperative endoscopic sinus surgery: a systematic review and meta-analysis.
Topics: Antibiotics, Antineoplastic; Constriction, Pathologic; Endoscopy; Humans; Mitomycin; Paranasal Sinus | 2013 |
Mitomycin C and endoscopic sinus surgery: where are we?
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Endoscopy; Humans; Mitomycin; Nasal Mucosa; Paranasa | 2007 |
[Mitomycin C in head and neck surgical procedures].
Topics: Alkylating Agents; Animals; Cicatrix; DNA; Fibroblasts; Follow-Up Studies; Humans; Mitomycin; Otorhi | 2007 |
11 trials available for mitomycin and Adhesions, Tissue
| Article | Year |
|---|---|
Treatment of post-adenotonsillectomy velopharyngeal stenosis with bivalved uvular flaps.
Topics: Adenoidectomy; Child; Child, Preschool; Combined Modality Therapy; Constriction, Pathologic; Female; | 2019 |
Management of bilateral congenital choanal atresia.
Topics: Choanal Atresia; Endoscopy; Female; Follow-Up Studies; Granulation Tissue; Humans; Infant, Newborn; | 2013 |
A novel technique for mitomycin-c application in frontal sinus surgery.
Topics: Administration, Topical; Adult; Aged; Chronic Disease; Cicatrix; Constriction, Pathologic; Cross-Ove | 2014 |
Intra- and postoperative application of Mitomycin C in the middle meatus reduces adhesions and antrostomy stenosis after FESS.
Topics: Administration, Topical; Adolescent; Adult; Aged; Cohort Studies; Constriction, Pathologic; Double-B | 2008 |
Postoperative maxillary sinus mucocoele: risk factors for restenosis after surgery and preventive effects of mytomycin-C.
Topics: Adult; Aged; Constriction, Pathologic; Double-Blind Method; Female; Humans; Male; Maxillary Sinus; M | 2009 |
Prevention of adhesion after endoscopic sinus surgery: role of mitomycin C.
Topics: Administration, Topical; Adolescent; Adult; Aged; Chronic Disease; Double-Blind Method; Endoscopy; F | 2011 |
Topical Mitomycin C in functional endoscopic sinus surgery.
Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Chronic Disease; Female; Humans; Male; | 2012 |
Evaluation of mitomycin C in reducing postoperative adhesions in strabismus surgery.
Topics: Adult; Aged; Double-Blind Method; Humans; Middle Aged; Mitomycin; Postoperative Complications; Prosp | 2005 |
Role of mitomycin C in reducing adhesion formation following endoscopic sinus surgery.
Topics: Adult; Antibiotics, Antineoplastic; Endoscopy; Female; Humans; Male; Mitomycin; Nasal Obstruction; P | 2006 |
Mitomycin C for the prevention of adhesion formation after endoscopic sinus surgery: a randomized, controlled study.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Endoscopy; Female; Follow-Up Studies; Humans; Male; Middle | 2002 |
Comparison of OK-432 and mitomycin C pleurodesis for malignant pleural effusion caused by lung cancer. A randomized trial.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Immunity, | 1992 |
46 other studies available for mitomycin and Adhesions, Tissue
| Article | Year |
|---|---|
Mitomycin C induces fibroblast apoptosis and reduces intra-articular scar adhesion by regulating miR-21 and its target Programmed cell death 4.
Topics: Alkylating Agents; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Survival; Cells, Cultured | 2020 |
Controlled release of Mitomycin C from modified cellulose based thermo-gel prevents post-operative de novo peritoneal adhesion.
Topics: Animals; Cell Adhesion; Cell Line; Cell Survival; Cellulose; Compressive Strength; Drug Carriers; Dr | 2020 |
The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Survival; Collagen Type I; Disease Models, Animal; | 2020 |
MMC controlled-release membranes attenuate epidural scar formation in rat models after laminectomy.
Topics: Animals; Cicatrix; Delayed-Action Preparations; Disease Models, Animal; Epidural Space; Fibrosis; La | 2017 |
Effective delivery of mitomycin-C and meloxicam by double-layer electrospun membranes for the prevention of epidural adhesions.
Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Chitosan; Drug Carriers; Drug Liberation; Dru | 2020 |
Prevention of retrosternal pericardial adhesions after cardiac surgery with mitomycin C.
Topics: Alkylating Agents; Animals; Cardiac Surgical Procedures; Cell Proliferation; Female; Fibroblasts; Mi | 2014 |
Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression.
Topics: Animals; Cell Adhesion Molecules; Delayed-Action Preparations; Diffusion; Electroplating; Gene Expre | 2015 |
Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Daunorubicin; Disease Models, Animal; Female; Fibros | 2016 |
Prevention of Intraabdominal Adhesions: An Experimental Study Using Mitomycin-C and 4% Icodextrin.
Topics: Alkylating Agents; Animals; Glucans; Glucose; Icodextrin; Mitomycin; Postoperative Complications; Ra | 2017 |
[In vitro drug release from a mitomycin C delivery system and its effect against scar tissue adhesion in vivo].
Topics: Animals; Chitosan; Drug Delivery Systems; Intervertebral Disc; Mitomycin; Polyethylene Glycols; Poly | 2008 |
The use of Mitomycin C to reduce adhesions and prevent restenosis of middle meatal antrostomy after FESS.
Topics: Administration, Topical; Adolescent; Adult; Aged; Constriction, Pathologic; Endoscopy; Female; Human | 2008 |
A thin honeycomb-patterned film as an adhesion barrier in an animal model of glaucoma filtration surgery.
Topics: Absorbable Implants; Animals; Blister; Conjunctival Diseases; Disease Models, Animal; Filtering Surg | 2009 |
The effect of mitomycin C as fibrosis preventive agent during craniectomies.
Topics: Administration, Topical; Animals; Arachnoid; Bone Regeneration; Craniotomy; Dura Mater; Female; Fibr | 2009 |
Use of pimecrolimus to prevent epidural fibrosis in a postlaminectomy rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Dura Mater; Fibrosis; Lam | 2009 |
Angiogenesis, fibrinogenesis and presence of synechiae after exeresis of a swine vocal fold mucosal microflap and use of topical mitomycin-C.
Topics: Animals; Collagen; Female; Fibrin; Laryngeal Mucosa; Male; Mitomycin; Models, Animal; Neovasculariza | 2010 |
Mitomycin C-polyethylene glycol controlled-release film inhibits collagen secretion and induces apoptosis of fibroblasts in the early wound of a postlaminectomy rat model.
Topics: Animals; Apoptosis; Cicatrix; Collagen; Delayed-Action Preparations; Drug Delivery Systems; Dura Mat | 2010 |
Failed back syndrome and epidural fibrosis.
Topics: Animals; Drug Delivery Systems; Epidural Space; Fibrosis; Humans; Low Back Pain; Lumbar Vertebrae; M | 2010 |
Adhesion reduction after knee surgery in a rat model by mitomycin C.
Topics: Animals; Cell Proliferation; Cicatrix; Disease Models, Animal; Female; Fibrosis; Foreign-Body Reacti | 2011 |
Effect of mitomycin-C on post-operative adhesions in tendon surgery: an experimental study in rats.
Topics: Achilles Tendon; Animals; Drug Evaluation, Preclinical; Female; Mitomycin; Nucleic Acid Synthesis In | 2010 |
The effect of mitomycin C in reducing intraarticular adhesion after knee surgery in rabbits.
Topics: Administration, Topical; Animals; Cell Count; Cicatrix; Collagen; Disease Models, Animal; Femur; Fib | 2010 |
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; | 2012 |
The effect of mitomycin-C in reducing pericardial adhesion after cardiac surgery in rabbits.
Topics: Animals; Antibiotics, Antineoplastic; Cardiac Surgical Procedures; Disease Models, Animal; Mitomycin | 2013 |
Adjuvant mitomycin C in functional endoscopic sinus surgery.
Topics: Female; Humans; Male; Mitomycin; Otorhinolaryngologic Surgical Procedures; Postoperative Complicatio | 2013 |
The use of Mitomycin-C to reduce synechia in middle meatus in sinus surgery: preliminary results.
Topics: Adult; Aged; Ear Diseases; Ear, Middle; Female; Humans; Male; Middle Aged; Mitomycin; Nasal Obstruct | 2012 |
Mitomycin C in preventing spinal epidural fibrosis in a laminectomy model in rats.
Topics: Alkylating Agents; Animals; Back Pain; Dose-Response Relationship, Drug; Dura Mater; Epidural Space; | 2004 |
Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits.
Topics: Animals; Cicatrix; Connective Tissue Diseases; Fluorouracil; Intraoperative Care; Mitomycin; Oculomo | 2004 |
Bioadhesive drug carriers for postoperative chemotherapy in bladder cancer.
Topics: Administration, Intravesical; Alginates; Animals; Antibiotics, Antineoplastic; Chitosan; Cross-Linki | 2004 |
Crosslinked hyaluronan hydrogels containing mitomycin C reduce postoperative abdominal adhesions.
Topics: Abdomen; Adjuvants, Immunologic; Animals; Cross-Linking Reagents; Drug Combinations; Female; Hyaluro | 2005 |
Mitomycin C, amniotic membrane transplantation and limbal conjunctival autograft for treating multirecurrent pterygia with symblepharon and motility restriction.
Topics: Adult; Alkylating Agents; Amnion; Cell Transplantation; Combined Modality Therapy; Conjunctiva; Conj | 2006 |
Mitomycin C effect on fibrous adhesions of rabbit temporomandibular joint.
Topics: Animals; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administrati | 2005 |
Intraoperative use of mitomycin C in fibrous atresia of the external auditory canal.
Topics: Adult; Constriction, Pathologic; Ear Canal; Female; Fibrosis; Follow-Up Studies; Humans; Male; Middl | 2005 |
The role of mitomycin C in reducing recurrence of epidural fibrosis after repeated operation in a laminectomy model in rats.
Topics: Alkylating Agents; Animals; Chi-Square Distribution; Epidural Space; Fibrosis; Laminectomy; Male; Mi | 2006 |
The effect of mitomycin C in reducing epidural fibrosis after lumbar laminectomy in rats.
Topics: Alkylating Agents; Animals; Epidural Space; Fibrosis; Laminectomy; Lumbar Vertebrae; Male; Mitomycin | 2006 |
Antiadhesive effects of mitomycin C and streptopeptidase A in rats with intraperitoneal adhesions.
Topics: Animals; Anti-Inflammatory Agents; Clostridium histolyticum; Disease Models, Animal; Hydroxyproline; | 2007 |
A comparison of the effectiveness of mitomycin C and 5-fluorouracil in the prevention of peridural adhesion after laminectomy.
Topics: Animals; Antimetabolites, Antineoplastic; Dura Mater; Fluorouracil; Laminectomy; Lumbar Vertebrae; M | 2007 |
A comparison of the local effectiveness of mitomycin C, aprotinin, and Adcon-L in experimental peridural fibrosis.
Topics: Animals; Aprotinin; Dura Mater; Epidural Space; Fibrosis; Laminectomy; Lumbar Vertebrae; Male; Mitom | 2008 |
Preoperative intraperitoneal chemotherapy for gastric cancer, with special reference to delayed peritoneal complications.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; F | 1995 |
Effects of mitomycin C on delayed adjustment in experimental strabismus surgery.
Topics: Administration, Topical; Animals; Chemotherapy, Adjuvant; Conjunctiva; Mitomycin; Oculomotor Muscles | 1995 |
Advantages and safety of local treatment with MMC/Beriplast P for cancer tumors.
Topics: Animals; Antibiotics, Antineoplastic; Aorta; Carcinoma, Squamous Cell; Delayed-Action Preparations; | 1996 |
The effect of mitomycin-C on the healing process in rabbit extraocular muscle surgery.
Topics: Animals; Cell Division; Conjunctiva; Fibroblast Growth Factor 2; Fibroblasts; Follow-Up Studies; Mit | 1999 |
Effects of intraperitoneal mitomycin C adsorbed on activated carbon on adhesion formation and mesothelial cells in vitro.
Topics: Animals; Charcoal; Disease Models, Animal; Epithelial Cells; Fibrinolysis; Humans; In Vitro Techniqu | 2000 |
An experimental study evaluating the effect of Mitomycin C on the prevention of postoperative intraabdominal adhesions.
Topics: Animals; Drug Evaluation; Female; Intestinal Diseases; Mitomycin; Nucleic Acid Synthesis Inhibitors; | 2001 |
Amniotic membrane transplantation in the management of conjunctival malignant melanoma and primary acquired melanosis with atypia.
Topics: Administration, Topical; Aged; Amnion; Conjunctival Neoplasms; Corneal Transplantation; Female; Huma | 2001 |
Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.
Topics: Adult; Antihypertensive Agents; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follow-Up Stud | 2001 |
Mitomycin-C prevents reformation of intra-abdominal adhesions after adhesiolysis.
Topics: Alkylating Agents; Animals; Female; Mitomycin; Peritoneal Diseases; Postoperative Complications; Rat | 2002 |
Postoperative instillation of mitomycin C in the treatment of recurrent pterygium.
Topics: Conjunctival Diseases; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Mitomycin; Mi | 1989 |