mitomycin has been researched along with Acute Kidney Injury in 14 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A thrombotic microangiopathy resembling the hemolytic uremic syndrome was diagnosed in 12 patients with adenocarcinoma, in whom the tumor was in complete or near-complete remission after treatment with mitomycin C-containing drug regimens." | 7.67 | Carcinoma-associated hemolytic-uremic syndrome: a complication of mitomycin C chemotherapy. ( Cantrell, JE; Phillips, TM; Schein, PS, 1985) |
| " Because previous studies showed that long-term telbivudine treatment improved renal function in chronic hepatitis B virus (HBV) infected patients, we conducted a case-control study to evaluate the clinical outcome of telbivudine preemptive therapy in HBV-related advanced HCC patients treated by combination chemotherapy comprising 5-fluorouracil, mitoxantrone and cisplatin (FMP)." | 5.19 | Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study. ( Chang, ML; Chen, YC; Chien, RN; Hsu, CW; Lin, CL; Yeh, C; Yeh, CT, 2014) |
| " Cisplatin and mitomycin C (MMC) are agents commonly used in these procedures and, individually, each has been associated with acute kidney injury (AKI)." | 3.91 | Assessment of nephrotoxicity associated with combined cisplatin and mitomycin C usage in laparoscopic hyperthermic intraperitoneal chemotherapy. ( Badgwell, B; Cata, JP; Hernandez, M; Kapoor, R; Mansfield, P; Owusu-Agyemang, P; Robinson, KA; Soliz, JM, 2019) |
| "Cisplatin (CDDP) and mitomycin C (MMC), two alkylating agents used against various solid tumours, are a common source of acute kidney injury." | 3.79 | Antioxidant and antigenotoxic role of recombinant human erythropoeitin against alkylating agents: cisplatin and mitomycin C in cultured Vero cells. ( Abid, S; Achour, A; Ayed-Boussema, I; Bacha, H; Rjiba-Touati, K; Soualeh, N, 2013) |
| "A thrombotic microangiopathy resembling the hemolytic uremic syndrome was diagnosed in 12 patients with adenocarcinoma, in whom the tumor was in complete or near-complete remission after treatment with mitomycin C-containing drug regimens." | 3.67 | Carcinoma-associated hemolytic-uremic syndrome: a complication of mitomycin C chemotherapy. ( Cantrell, JE; Phillips, TM; Schein, PS, 1985) |
| "Fourteen patients with adenocarcinoma of the gastrointestinal tract and pancreas treated with mitomycin C(MMC) and 5-fluorouracil (5-FU) had renal impairment 6-11 months from the beginning of MMC therapy." | 3.66 | Renal disease after mitomycin C therapy. ( Hanna, WT; Krauss, S; Murphy, WM; Regester, RF, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Figueiredo, FA | 1 |
| Ramos, LEF | 1 |
| Silva, RT | 1 |
| Ponce, D | 1 |
| de Carvalho, RLR | 1 |
| Schwarzbold, AV | 1 |
| Maurílio, AO | 1 |
| Scotton, ALBA | 1 |
| Garbini, AF | 1 |
| Farace, BL | 1 |
| Garcia, BM | 1 |
| da Silva, CTCA | 1 |
| Cimini, CCR | 1 |
| de Carvalho, CA | 1 |
| Dias, CDS | 1 |
| Silveira, DV | 1 |
| Manenti, ERF | 1 |
| Cenci, EPA | 1 |
| Anschau, F | 1 |
| Aranha, FG | 1 |
| de Aguiar, FC | 1 |
| Bartolazzi, F | 1 |
| Vietta, GG | 1 |
| Nascimento, GF | 1 |
| Noal, HC | 1 |
| Duani, H | 1 |
| Vianna, HR | 1 |
| Guimarães, HC | 1 |
| de Alvarenga, JC | 1 |
| Chatkin, JM | 1 |
| de Morais, JDP | 1 |
| Machado-Rugolo, J | 1 |
| Ruschel, KB | 1 |
| Martins, KPMP | 1 |
| Menezes, LSM | 1 |
| Couto, LSF | 1 |
| de Castro, LC | 1 |
| Nasi, LA | 1 |
| Cabral, MAS | 1 |
| Floriani, MA | 1 |
| Souza, MD | 1 |
| Souza-Silva, MVR | 1 |
| Carneiro, M | 1 |
| de Godoy, MF | 1 |
| Bicalho, MAC | 1 |
| Lima, MCPB | 1 |
| Aliberti, MJR | 1 |
| Nogueira, MCA | 1 |
| Martins, MFL | 1 |
| Guimarães-Júnior, MH | 1 |
| Sampaio, NDCS | 1 |
| de Oliveira, NR | 1 |
| Ziegelmann, PK | 1 |
| Andrade, PGS | 1 |
| Assaf, PL | 1 |
| Martelli, PJL | 1 |
| Delfino-Pereira, P | 1 |
| Martins, RC | 1 |
| Menezes, RM | 1 |
| Francisco, SC | 1 |
| Araújo, SF | 1 |
| Oliveira, TF | 1 |
| de Oliveira, TC | 1 |
| Sales, TLS | 1 |
| Avelino-Silva, TJ | 1 |
| Ramires, YC | 1 |
| Pires, MC | 1 |
| Marcolino, MS | 1 |
| Lu, PW | 1 |
| Fields, AC | 1 |
| Shabat, G | 1 |
| Bleday, R | 1 |
| Goldberg, JE | 1 |
| Irani, J | 1 |
| Stopfkuchen-Evans, M | 1 |
| Melnitchouk, N | 1 |
| Baratti, D | 1 |
| Sammartino, P | 1 |
| Kusamura, S | 1 |
| Deraco, M | 1 |
| Ansaloni, L | 1 |
| Asero, S | 1 |
| Baiocchi, G | 1 |
| Bagnoli, P | 1 |
| Cavaliere, D | 1 |
| Framarini, M | 1 |
| Cirocchi, R | 1 |
| Coccolini, F | 1 |
| Decian, F | 1 |
| Delrio, P | 1 |
| Sassaroli, C | 1 |
| De Simone, M | 1 |
| Robella, M | 1 |
| Vaira, M | 1 |
| Di Giorgio, A | 1 |
| Fagotti, A | 1 |
| Lorusso, D | 1 |
| Federici, O | 1 |
| Fiorentini, G | 1 |
| Fambrini, M | 1 |
| Scaringi, S | 1 |
| Garofalo, A | 1 |
| Valle, M | 1 |
| Gelmini, R | 1 |
| Cabry, F | 1 |
| Cautero, N | 1 |
| Sorrentino, L | 1 |
| Graziosi, L | 1 |
| Guaglio, M | 1 |
| Montenovo, M | 1 |
| Bartolini, V | 1 |
| Lippolis, PV | 1 |
| Macrì, A | 1 |
| Pasqual, EM | 1 |
| Roviello, F | 1 |
| Marrelli, D | 1 |
| Orsenigo, E | 1 |
| Sommariva, A | 1 |
| Kapoor, R | 1 |
| Robinson, KA | 1 |
| Cata, JP | 1 |
| Owusu-Agyemang, P | 1 |
| Soliz, JM | 1 |
| Hernandez, M | 1 |
| Mansfield, P | 1 |
| Badgwell, B | 1 |
| Rjiba-Touati, K | 1 |
| Ayed-Boussema, I | 1 |
| Soualeh, N | 1 |
| Achour, A | 1 |
| Bacha, H | 1 |
| Abid, S | 1 |
| Lin, CL | 1 |
| Chien, RN | 1 |
| Yeh, C | 1 |
| Hsu, CW | 1 |
| Chang, ML | 1 |
| Chen, YC | 1 |
| Yeh, CT | 1 |
| Bouhadjari, N | 1 |
| Gabato, W | 1 |
| Calabrese, D | 1 |
| Msika, S | 1 |
| Keita, H | 1 |
| Hanna, WT | 1 |
| Krauss, S | 1 |
| Regester, RF | 1 |
| Murphy, WM | 1 |
| Kreusser, W | 1 |
| Herrmann, R | 1 |
| Tschöpe, W | 1 |
| Ritz, E | 1 |
| Godes, M | 1 |
| Camps, C | 1 |
| Martínez, A | 1 |
| Farha, AJ | 1 |
| Krauss, DJ | 1 |
| Sagawa, M | 1 |
| Sakuma, T | 1 |
| Takahashi, S | 1 |
| Usuda, K | 1 |
| Satoh, M | 1 |
| Kamma, K | 1 |
| Ohta, S | 1 |
| Nagamoto, N | 1 |
| Imai, T | 1 |
| Saitoh, Y | 1 |
| D'Elia, JA | 1 |
| Aslani, M | 1 |
| Schermer, S | 1 |
| Cloud, L | 1 |
| Bothe, A | 1 |
| Dzik, W | 1 |
| Cantrell, JE | 1 |
| Phillips, TM | 1 |
| Schein, PS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Observational, Single-center Post-marketing Surveillance Study of Telbivudine in Chronic Hepatitis B Adults With HBeAg Positive/Negative.[NCT00970216] | 160 participants (Actual) | Observational | 2009-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00970216)
Timeframe: 48 weeks
| Intervention | participants (Number) |
|---|---|
| Chronic Hepatitis B | 79 |
2 reviews available for mitomycin and Acute Kidney Injury
| Article | Year |
|---|---|
Nephrological complications of cancer therapy.
Topics: Acute Kidney Injury; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Humans; Ifosfamide; Kidney; | 1982 |
Hemolytic-uremic syndrome and acute renal failure in metastatic adenocarcinoma treated with mitomycin: case report and literature review.
Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast N | 1987 |
1 trial available for mitomycin and Acute Kidney Injury
| Article | Year |
|---|---|
Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study.
Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc | 2014 |
11 other studies available for mitomycin and Acute Kidney Injury
| Article | Year |
|---|---|
Development and validation of the MMCD score to predict kidney replacement therapy in COVID-19 patients.
Topics: Acute Kidney Injury; Adult; Aged; COVID-19; Dextrans; Female; Humans; Male; Middle Aged; Mitomycin; | 2022 |
Cytoreductive Surgery and HIPEC in an Enhanced Recovery After Surgery Program: A Feasibility Study.
Topics: Acute Kidney Injury; Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Cytoreduction Surgi | 2020 |
Past, present and future of adjuvant HIPEC in patients at high risk for colorectal peritoneal metastases.
Topics: Acute Kidney Injury; Anastomotic Leak; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, | 2020 |
Assessment of nephrotoxicity associated with combined cisplatin and mitomycin C usage in laparoscopic hyperthermic intraperitoneal chemotherapy.
Topics: Acute Kidney Injury; Adult; Aged; Cisplatin; Combined Modality Therapy; Female; Humans; Hyperthermia | 2019 |
Antioxidant and antigenotoxic role of recombinant human erythropoeitin against alkylating agents: cisplatin and mitomycin C in cultured Vero cells.
Topics: Acute Kidney Injury; Alkylating Agents; Animals; Antioxidants; Cells, Cultured; Chlorocebus aethiops | 2013 |
Hyperthermic intraperitoneal chemotherapy with cisplatin: Amifostine prevents acute severe renal impairment.
Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy P | 2016 |
Renal disease after mitomycin C therapy.
Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Aged; Blood Pressure; Blood Urea Nitrogen; Creatinine; F | 1981 |
[Microangiopathic hemolytic anemia associated with mitomycin-C treatment].
Topics: Acute Kidney Injury; Anemia, Hemolytic; Humans; Male; Middle Aged; Mitomycin | 1991 |
Renal failure after intravesical mitomycin C.
Topics: Acute Kidney Injury; Administration, Intravesical; Carcinoma in Situ; Carcinoma, Transitional Cell; | 1989 |
[Microangiopathic hemolytic anemia (MAHA) and renal failure induced by anti-neoplastic agents--a case report].
Topics: Acute Kidney Injury; Aged; Anemia, Hemolytic; Antineoplastic Agents; Antineoplastic Combined Chemoth | 1987 |
Carcinoma-associated hemolytic-uremic syndrome: a complication of mitomycin C chemotherapy.
Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Anemia, Hemolytic; Antibiotics, Antineoplastic; Antigen- | 1985 |