mitomycin has been researched along with Acute Disease in 23 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C." | 8.81 | Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature. ( Lin, JM; Shy, JD; Tsai, YY, 2002) |
| "We report a case of acute fatal respiratory failure following mitomycin and vinblastine administration in a patient with metastatic breast cancer." | 8.77 | Fatal acute respiratory failure following vinblastine and mitomycin administration for breast cancer. ( Ballen, KK; Weiss, ST, 1988) |
| "With adequate inflammation suppression, phacotrabeculectomy with mitomycin C is an effective and safe therapeutic option for the management of secondary cataract and glaucoma in uveitic eyes." | 7.73 | Phacotrabeculectomy with mitomycin C in patients with uveitis. ( Ahn, JK; Park, KH; Park, UC; Yu, HG, 2006) |
| "To conduct a prospective, randomized, controlled trial determining the feasibility of radiofrequency with or without topical mitomycin C application in delaying the closure time of human tympanostomy and screening its efficacy in management of recurrent acute otitis media and otitis media with effusion." | 5.11 | The effect of radiofrequency and mitomycin C on the closure rate of human tympanostomy. ( Ragab, SM, 2005) |
| "To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C." | 4.81 | Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature. ( Lin, JM; Shy, JD; Tsai, YY, 2002) |
| "We report a case of acute fatal respiratory failure following mitomycin and vinblastine administration in a patient with metastatic breast cancer." | 4.77 | Fatal acute respiratory failure following vinblastine and mitomycin administration for breast cancer. ( Ballen, KK; Weiss, ST, 1988) |
| "PRéCIS:: The present study suggests that immediate trabeculectomy with mitomycin C (MMC) may be performed as a safe and effective intervention in the management of refractory ocular hypertension (OHT)/glaucoma in patients with bilateral acute iris transillumination (BAIT)." | 3.91 | Long-term Results of Trabeculectomy With Mitomycin-C in Patients With Bilateral Acute Iris Transillumination. ( Altan, C; Basarir, B; Bayraktar, S; Izgi, B; Oray, M; Tugal-Tutkun, I, 2019) |
| "NRG Oncology RTOG 0529 assessed the feasibility of dose-painted intensity modulated radiation therapy (DP-IMRT) to reduce the acute morbidity of chemoradiation with 5-fluorouracil (5FU) and mitomycin-C (MMC) for T2-4N0-3M0 anal cancer." | 3.85 | Predictors of Radiation Therapy-Related Gastrointestinal Toxicity From Anal Cancer Dose-Painted Intensity Modulated Radiation Therapy: Secondary Analysis of NRG Oncology RTOG 0529. ( Abitbol, A; Chang, A; Chen, Y; Crane, CH; Doncals, DE; Fisher, B; Johnson, D; Kachnic, L; Michalski, J; Moughan, J; Myerson, R; Narayan, S; Olsen, JR; Schefter, TE, 2017) |
| " In this study, we examined the effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG), an active component extracted from Polygonum multiflorum Thunb, on acetic acid-induced acute colitis and mitomycin C-induced chronic colitis." | 3.74 | Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. ( Chen, S; Han, T; Wang, J; Wang, X; Zhao, L, 2008) |
| "With adequate inflammation suppression, phacotrabeculectomy with mitomycin C is an effective and safe therapeutic option for the management of secondary cataract and glaucoma in uveitic eyes." | 3.73 | Phacotrabeculectomy with mitomycin C in patients with uveitis. ( Ahn, JK; Park, KH; Park, UC; Yu, HG, 2006) |
| "A patient with mitomycin-associated hemolytic-uremic syndrome received SPA treatments after her ACE inhibitor, lisinopril, was held." | 3.71 | Hypotensive reaction during staphylococcal protein A column therapy in a patient with anomalous degradation of bradykinin and Des-Arg9-bradykinin after contact activation. ( Adam, A; Eastlund, T; Hammerschmidt, D; Koenigbauer, U; Lepage, Y; Molinaro, G, 2002) |
| "Of 1774 patients with breast cancer given mitoxantrone (MTZ) with methotrexate (n = 492) or with methotrexate and mitomycin C (n = 1282), nine developed MDS/AML after a median of 2." | 3.70 | Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma. ( Ashley, S; Kuan, A; Kulkarni, S; Mehta, J; Mitchell, P; Powles, R; Powles, T; Saso, R; Swansbury, GJ; Treleaven, J, 2000) |
| "5 mg/kg of mitomycin-C (Mit-C) resulted in 70% (n = 20) and 71% (n = 14) mortality, respectively, from 2 to 7 days after perfusion, with extensive, patchy necrosis and infarction seen on histologic examination and markedly elevated levels of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) at 6 and 24 hours after perfusion." | 3.66 | Reversal of lethal, chemotherapeutically induced acute hepatic necrosis in rats by regenerating liver cytosol. ( Falk, JA; Falk, RE; Falk, W; Makowka, L; Miyazaki, M; Venturi, D, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 12 (52.17) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Janetka, JW | 1 |
| Hopper, AT | 1 |
| Yang, Z | 1 |
| Barks, J | 1 |
| Dhason, MS | 1 |
| Wang, Q | 1 |
| Sibley, LD | 1 |
| Olsen, JR | 1 |
| Moughan, J | 1 |
| Myerson, R | 1 |
| Abitbol, A | 1 |
| Doncals, DE | 1 |
| Johnson, D | 1 |
| Schefter, TE | 1 |
| Chen, Y | 1 |
| Fisher, B | 1 |
| Michalski, J | 1 |
| Narayan, S | 1 |
| Chang, A | 1 |
| Crane, CH | 1 |
| Kachnic, L | 1 |
| Bayraktar, S | 1 |
| Oray, M | 1 |
| Altan, C | 1 |
| Basarir, B | 1 |
| Izgi, B | 1 |
| Tugal-Tutkun, I | 1 |
| Liu, L | 1 |
| Wang, F | 1 |
| Zheng, Y | 1 |
| Yuan, X | 1 |
| Wang, D | 1 |
| Zeng, W | 1 |
| He, X | 1 |
| Wang, C | 1 |
| Deng, S | 1 |
| Franco, P | 1 |
| Ragona, R | 1 |
| Arcadipane, F | 1 |
| Mistrangelo, M | 1 |
| Cassoni, P | 1 |
| Rondi, N | 1 |
| Morino, M | 1 |
| Racca, P | 1 |
| Ricardi, U | 1 |
| Adyanthaya, RS | 1 |
| Folgar, FA | 1 |
| Akpek, EK | 1 |
| Blalock, WL | 1 |
| Bavelloni, A | 1 |
| Piazzi, M | 1 |
| Tagliavini, F | 1 |
| Faenza, I | 1 |
| Martelli, AM | 1 |
| Follo, MY | 1 |
| Cocco, L | 1 |
| Molinaro, G | 1 |
| Adam, A | 1 |
| Lepage, Y | 1 |
| Hammerschmidt, D | 1 |
| Koenigbauer, U | 1 |
| Eastlund, T | 1 |
| Amadori, S | 1 |
| Suciu, S | 1 |
| Willemze, R | 1 |
| Mandelli, F | 1 |
| Selleslag, D | 1 |
| Stauder, R | 1 |
| Ho, A | 1 |
| Denzlinger, C | 1 |
| Leone, G | 1 |
| Fabris, P | 1 |
| Muus, P | 1 |
| Vignetti, M | 1 |
| Hagemeijer, A | 1 |
| Beeldens, F | 1 |
| Anak, O | 1 |
| De Witte, T | 1 |
| Chen, F | 1 |
| Medhurst, AL | 1 |
| de Winter, JP | 1 |
| Waisfisz, Q | 1 |
| Rooimans, MA | 1 |
| Oostra, AB | 1 |
| Meyer, S | 1 |
| Zhang, KJ | 1 |
| Xia, B | 1 |
| Pals, G | 1 |
| Arwert, F | 1 |
| Zwaan, CM | 1 |
| Joenje, H | 1 |
| González-Moreno, S | 1 |
| Brun, E | 1 |
| Sugarbaker, PH | 1 |
| Ragab, SM | 1 |
| Mitchell, J | 1 |
| Keung, YK | 1 |
| Park, UC | 1 |
| Ahn, JK | 1 |
| Park, KH | 1 |
| Yu, HG | 1 |
| Wang, X | 1 |
| Zhao, L | 1 |
| Han, T | 1 |
| Chen, S | 1 |
| Wang, J | 1 |
| Miyazaki, M | 1 |
| Makowka, L | 1 |
| Falk, RE | 1 |
| Falk, JA | 1 |
| Falk, W | 1 |
| Venturi, D | 1 |
| Philpott, NJ | 1 |
| Bevan, DH | 1 |
| Gordon-Smith, EC | 1 |
| Raderer, M | 1 |
| Kornek, G | 1 |
| Hejna, M | 1 |
| Vorbeck, F | 1 |
| Weinlaender, G | 1 |
| Scheithauer, W | 1 |
| Saso, R | 1 |
| Kulkarni, S | 1 |
| Mitchell, P | 1 |
| Treleaven, J | 1 |
| Swansbury, GJ | 1 |
| Mehta, J | 1 |
| Powles, R | 1 |
| Ashley, S | 1 |
| Kuan, A | 1 |
| Powles, T | 1 |
| Uoshima, N | 1 |
| Yoshioka, K | 1 |
| Tegoshi, H | 1 |
| Wada, S | 1 |
| Fujiwara, Y | 1 |
| Satake, N | 1 |
| Kasamatsu, Y | 1 |
| Yokoho, S | 1 |
| Tsai, YY | 1 |
| Lin, JM | 1 |
| Shy, JD | 1 |
| Bilfinger, TV | 1 |
| Hartman, AR | 1 |
| Ballen, KK | 1 |
| Weiss, ST | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neoadjuvant PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced Anal Canal Squamous Carcinoma Patients[NCT05060471] | Phase 2 | 27 participants (Anticipated) | Interventional | 2021-09-08 | Enrolling by invitation | ||
| Gemtuzumab Ozogamicin (CMA-676) Followed or Not by Intensive Chemotherapy as Initial Treatment for Elderly Patients With Acute Myeloid Leukemia: An EORTC-LG Pilot Phase II Study[NCT00006122] | Phase 2 | 106 participants (Actual) | Interventional | 2000-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mitomycin and Acute Disease
| Article | Year |
|---|---|
Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature.
Topics: Acute Disease; Humans; Intraoperative Period; Lactose; Lubrication; Male; Methylcellulose; Middle Ag | 2002 |
Fatal acute respiratory failure following vinblastine and mitomycin administration for breast cancer.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Hypersen | 1988 |
2 trials available for mitomycin and Acute Disease
| Article | Year |
|---|---|
Sequential administration of gemtuzumab ozogamicin and conventional chemotherapy as first line therapy in elderly patients with acute myeloid leukemia: a phase II study (AML-15) of the EORTC and GIMEMA leukemia groups.
Topics: Acute Disease; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant | 2004 |
The effect of radiofrequency and mitomycin C on the closure rate of human tympanostomy.
Topics: Acute Disease; Catheter Ablation; Child; Child, Preschool; Equipment Design; Feasibility Studies; Fe | 2005 |
19 other studies available for mitomycin and Acute Disease
| Article | Year |
|---|---|
Optimizing Pyrazolopyrimidine Inhibitors of Calcium Dependent Protein Kinase 1 for Treatment of Acute and Chronic Toxoplasmosis.
Topics: Acute Disease; Animals; Binding Sites; Cell Line; Cell Proliferation; Chronic Disease; Crystallograp | 2020 |
Predictors of Radiation Therapy-Related Gastrointestinal Toxicity From Anal Cancer Dose-Painted Intensity Modulated Radiation Therapy: Secondary Analysis of NRG Oncology RTOG 0529.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Co | 2017 |
Long-term Results of Trabeculectomy With Mitomycin-C in Patients With Bilateral Acute Iris Transillumination.
Topics: Acute Disease; Adult; Aged; Alkylating Agents; Antihypertensive Agents; Conjunctiva; Female; Follow- | 2019 |
Pretreatment of transfused donor splenocytes and allografts with mitomycin C attenuates acute rejection in heart transplantation in mice.
Topics: Acute Disease; Allografts; Animals; Apoptosis; Graft Rejection; Graft Survival; Heart; Heart Transpl | 2014 |
Dosimetric predictors of acute hematologic toxicity during concurrent intensity-modulated radiotherapy and chemotherapy for anal cancer.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus | 2017 |
Medical management of acutely recurring pterygium with topical mitomycin-C.
Topics: Acute Disease; Administration, Topical; Adult; Alkylating Agents; Female; Humans; Male; Middle Aged; | 2009 |
Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress.
Topics: Acute Disease; Amino Acid Sequence; Cell Line, Tumor; Cell Nucleus; DNA Damage; eIF-2 Kinase; Humans | 2011 |
Hypotensive reaction during staphylococcal protein A column therapy in a patient with anomalous degradation of bradykinin and Des-Arg9-bradykinin after contact activation.
Topics: Acute Disease; Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Combined Ch | 2002 |
Apparent absence of BRCA2 protein in a proportion of acute myeloid leukemia cell lines.
Topics: Acute Disease; Antibiotics, Antineoplastic; BRCA2 Protein; Drug Resistance, Neoplasm; Humans; Leukem | 2004 |
Lymph node metastasis in epithelial malignancies of the appendix with peritoneal dissemination does not reduce survival in patients treated by cytoreductive surgery and perioperative intraperitoneal chemotherapy.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Combine | 2005 |
Acute myeloid leukemia following intraperitoneal hyperthermic mitomycin C.
Topics: Acute Disease; Adenocarcinoma; Adult; Chromosome Inversion; Chromosomes, Human, Pair 16; Female; Hum | 2006 |
Phacotrabeculectomy with mitomycin C in patients with uveitis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Alkylating Agents; Case-Control Studies; Cataract; Co | 2006 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Coliti | 2008 |
Reversal of lethal, chemotherapeutically induced acute hepatic necrosis in rats by regenerating liver cytosol.
Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Cytosol; Fluorouracil; Hyperthermia, | 1983 |
Secondary leukaemia after MMM combined modality therapy for breast carcinoma.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; F | 1993 |
Acute pulmonary toxicity associated with high-dose vinorelbine and mitomycin C.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dose-Response Relat | 1996 |
Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neopl | 2000 |
Acute respiratory failure caused by vinorelbine tartrate in a patient with non-small cell lung cancer.
Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic | 2001 |
Acute pulmonary failure with neoadjuvant protocol including mitomycin C and surgical therapy.
Topics: Acute Disease; Combined Modality Therapy; Humans; Lung; Lung Neoplasms; Mitomycin; Respiratory Insuf | 1991 |