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mitomycin and Abnormalities, Drug-Induced

mitomycin has been researched along with Abnormalities, Drug-Induced in 11 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"One of the key obstacles against the success in cancer chemotherapy is the toxic and side effects of the chemotherapeutic agents."1.36Using activated carbon nanoparticles to decrease the genotoxicity and teratogenicity of anticancer therapeutic agents. ( Shuzheng, M; Yingge, Z; Zhong, Y, 2010)
"When mitomycin-C treatment alone was performed on day 9."1.27Teratogenic interactions between methylmercury and mitomycin-C in mice. ( Inouye, M; Kajiwara, Y, 1988)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhong, Y1
Shuzheng, M1
Yingge, Z1
BIELIAVSKY, N1
Gregg, BC1
Snow, MH2
Fujii, T2
Nakatsuka, T2
Hanada, S1
Rutledge, J1
Nagao, T2
Saitoh, Y1
Yoshimura, S1
Pagano, G1
Degan, P1
De Biase, A1
Iaccarino, M1
Warnau, M1
Fujikawa, K1
Inouye, M1
Kajiwara, Y1

Other Studies

11 other studies available for mitomycin and Abnormalities, Drug-Induced

ArticleYear
Using activated carbon nanoparticles to decrease the genotoxicity and teratogenicity of anticancer therapeutic agents.
    Journal of nanoscience and nanotechnology, 2010, Volume: 10, Issue:12

    Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Cell Line; Cell Line, Tumor

2010
[EFFECTS OF MITOMYCIN ON THE INCORPORATION OF TRITIATED THYMIDINE INTO AMPHIBIAN EMBRYOS AT THE MORULA STAGE].
    Experimental cell research, 1963, Volume: 32

    Topics: Abnormalities, Drug-Induced; Amphibians; Animals; Cell Division; DNA; Embryo, Mammalian; Embryo, Non

1963
Axial abnormalities following disturbed growth in mitomycin C-treated mouse embryos.
    Journal of embryology and experimental morphology, 1983, Volume: 73

    Topics: Abnormalities, Drug-Induced; Animals; Cervical Vertebrae; Lumbar Vertebrae; Mice; Mice, Inbred Strai

1983
Potentiating effects of caffeine on teratogenicity of alkylating agents in mice.
    Teratology, 1983, Volume: 28, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Alkylating Agents; Animals; Antibioti

1983
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
    Teratology, 1983, Volume: 28, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female;

1983
Preimplantation teratology and the placenta.
    Teratology, 2000, Volume: 61, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Blastocyst; Female; Humans; Mitom

2000
Possible mechanism of congenital malformations induced by exposure of mouse preimplantation embryos to mitomycin C.
    Teratology, 2000, Volume: 61, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Decidua; Embryonic and Fetal Development; Female;

2000
Diepoxybutane and mitomycin C toxicity is associated with the induction of oxidative DNA damage in sea urchin embryos.
    Human & experimental toxicology, 2001, Volume: 20, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Abnormalities, Drug-Induced; Animals; Deoxyguanosine; DNA Damage; Dose-

2001
Genotoxic potency in mouse spermatogonial stem cells of triethylenemelamine, mitomycin C, ethylnitrosourea, procarbazine, and propyl methanesulfonate as measured by F1 congenital defects.
    Mutation research, 1990, Volume: 229, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Ethylnitrosourea; Male; Mesylates; Mice; Mice, Inbred ICR; Mit

1990
Teratogenic interactions between methylmercury and mitomycin-C in mice.
    Archives of toxicology, 1988, Volume: 61, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cleft Palate; Drug Synergism; Female; Methylme

1988
Restorative growth and its problems for morphogenesis.
    Progress in clinical and biological research, 1985, Volume: 163C

    Topics: Abnormalities, Drug-Induced; Animals; Cell Cycle; Cell Differentiation; Cell Division; Embryo, Mamma

1985