mithramycin-sk has been researched along with Leukemia--Lymphocytic--Chronic--B-Cell* in 1 studies
1 other study(ies) available for mithramycin-sk and Leukemia--Lymphocytic--Chronic--B-Cell
| Article | Year |
|---|---|
The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling.
B-cell receptor (BCR)-dependent signaling is central for leukemia B-cell homeostasis, as underscored by the promising clinical results obtained in patients with chronic lymphocytic leukemia (CLL) treated with novel agents targeting components of this pathway. Herein, we demonstrate that the mithralog EC-7072 displays high Topics: Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Cell Survival; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Interferon-gamma; Killer Cells, Natural; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphorylation; Plicamycin; Receptors, Antigen, B-Cell; Signal Transduction; T-Lymphocytes; Tumor Cells, Cultured; Tumor Microenvironment | 2019 |