misoprostol and Fasciitis--Necrotizing

Group A Streptococcus is an aerobic gram-positive bacteria known to cause cutaneous infections. Invasive infections can lead to toxic shock syndrome with multiorgan failure and mortality rates of 25-48%.. A healthy, young woman developed necrotizing fasciitis, myonecrosis, and toxic shock syndrome after an elective medical termination of pregnancy. This patient had confirmed group A Streptococcus on blood cultures and underwent surgical debridement. After aggressive surgical treatment, below-the-knee amputation, and antibiotic therapy, the patient survived.. This case demonstrates the need for prompt recognition and treatment of necrotizing fasciitis/toxic shock syndrome.

Topics: Abortifacient Agents; Abortion, Induced; Amputation, Surgical; Fasciitis, Necrotizing; Female; Humans; Mifepristone; Misoprostol; Shock, Septic; Streptococcal Infections; Streptococcus pyogenes; Young Adult