misonidazole has been researched along with Melanoma in 20 studies
*Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (95.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denny, WA; Hay, MP; Lee, HH; Roberts, PB; Wilson, WR | 1 |
| Brustad, T; Rofstad, EK | 3 |
| Blekkenhorst, G; Cridland, S; Korrubel, J; Sealy, R | 1 |
| Adams, GE; Ahmed, I; Chaplin, DJ; Sheldon, PW | 1 |
| Curtis, S; Guichard, M; Malaise, EP; Tenforde, T | 1 |
| Clutterbuck, RD; McElwain, TJ; Millar, JL | 1 |
| Glatte, P; Haedecke, U; Osieka, R; Schmidt, CG | 1 |
| Rofstad, EK | 1 |
| Gueulette, J; Guichard, M; Malaise, EP; Octave-Prignot, M; Wambersie, A | 1 |
| de Langen-Omri, F; Guichard, M; Malaise, EP | 1 |
| Deacon, J; Holliday, S; Stratford, IJ; Walling, JM | 1 |
| Adams, GE; Cole, S; Stratford, IJ | 1 |
| Chapman, JD; Kanclerz, A | 1 |
| Chapman, JD; Franko, AJ; Koch, CJ; Raleigh, JA; Urtasun, RC | 2 |
| Ahmed, I; Deacon, JM; Holliday, SB; Jenkins, TC | 1 |
| Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Saunders, MI; Stratford, MR; Wardman, P | 1 |
| Guichard, M; Lespinasse, F; Malaise, EP | 1 |
20 other study(ies) available for misonidazole and Melanoma
| Article | Year |
|---|---|
Hypoxia-selective antitumor agents. 10. bis(nitroimidazoles) and related Bis(nitroheterocycles): development of derivatives with higher rates of metabolic activation under hypoxia and improved aqueous solubility.
Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Hypoxia; Cell Line; Chemical Phenomena; Chemistry, Physical; Cricetinae; Cricetulus; Heterocyclic Compounds; Humans; Mammary Neoplasms, Experimental; Melanoma; Mice; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Solubility; Structure-Activity Relationship; Water | 1995 |
Broad-shouldered survival curves of a human melanoma xenograft. Implications for radiation therapy in the absence and presence of misonidazole.
Topics: Animals; Humans; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Prognosis; Radiation-Sensitizing Agents; Transplantation, Heterologous | 1981 |
Interstitial misonidazole. A preliminary report on a new perspective in clinical radiation sensitization and hypoxic cell chemotherapy.
Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Injections; Male; Melanoma; Middle Aged; Misonidazole; Nitroimidazoles; Skin Neoplasms | 1984 |
Potentiation of cyclophosphamide cytotoxicity in vivo: a study with misonidazole and fifteen other 1-substituted 2-nitroimidazoles.
Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors | 1984 |
Effect of combined misonidazole and accelerated neon ions on a human melanoma transplanted into nude mice.
Topics: Animals; Cell Survival; Colony-Forming Units Assay; Female; Male; Melanoma; Mice; Mice, Nude; Misonidazole; Neon; Neoplasm Transplantation; Nitroimidazoles; Radiotherapy, High-Energy; Skin Neoplasms | 1982 |
Misonidazole enhancement of the action of BCNU and melphalan against human melanoma xenografts.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; Cell Line; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Melphalan; Mice; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Transplantation, Heterologous | 1982 |
[Enhancement of MeCCNU potency (chemosensitization) by misonidazole in a human melanoma xenograft system].
Topics: Animals; Cell Line; Drug Interactions; Female; Humans; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Semustine | 1982 |
Radiation response of the cells of a human malignant melanoma xenograft. Effect of hypoxic cell radiosensitizers.
Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Humans; In Vitro Techniques; Injections, Intraperitoneal; Male; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Time Factors; Transplantation, Heterologous | 1981 |
Effect of combined misonidazole and d(50)-Be neutrons on a human melanoma transplanted into nude mice.
Topics: Animals; Cell Line; Cell Survival; DNA Repair; Fast Neutrons; Half-Life; Humans; Injections, Intraperitoneal; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Neutrons; Nitroimidazoles; Radiotherapy Dosage; Time Factors; Transplantation, Heterologous | 1980 |
Radiosensitization by misonidazole of a human malignant melanoma grown in athymic nude mice.
Topics: Animals; Humans; Male; Melanoma; Mice; Mice, Nude; Misonidazole; Radiography; Radiotherapy Dosage | 1980 |
Radiosensitizing effect of misonidazole in fractionated gamma-ray treatment of a human malignant melanoma grown in athymic nude mice.
Topics: Animals; Gamma Rays; Humans; Male; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiotherapy Dosage; Time Factors; Transplantation, Heterologous | 1979 |
Influence of misonidazole on the radiosensitivity of a human melanoma in nude mice: time-dependent increase in surviving fraction.
Topics: Animals; Cell Survival; Female; Humans; Hypoxia; In Vitro Techniques; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Time Factors | 1979 |
High uptake of RSU 1069 and its analogues melanotic melanomas.
Topics: Animals; Cell Line; Cell Membrane Permeability; Deoxyribonucleases; Drug Evaluation, Preclinical; Half-Life; Humans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Microbial Collagenase; Misonidazole; Sarcoma, Experimental; Tissue Distribution; Trypsin; Tumor Cells, Cultured | 1989 |
Manipulation of radiobiological hypoxia in a human melanoma xenograft to exploit the bioreductive cytotoxicity of RSU-1069.
Topics: Animals; Cell Hypoxia; Combined Modality Therapy; Constriction; Female; Hydralazine; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Radiation-Sensitizing Agents; Transplantation, Heterologous | 1989 |
Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice.
Topics: Amifostine; Animals; Etanidazole; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Metastasis; Neoplasms, Experimental; Nitroimidazoles; Radiation-Protective Agents; Radiation-Sensitizing Agents | 1988 |
Binding of 3H-misonidazole to solid human tumors as a measure of tumor hypoxia.
Topics: Autoradiography; Carcinoma, Small Cell; Humans; Lung Neoplasms; Melanoma; Misonidazole; Neoplasms; Oxygen; Tritium | 1986 |
Experimental pharmacokinetics of RSU-1069 and its analogues: high tumor/plasma ratios.
Topics: Animals; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Radiation-Sensitizing Agents | 1986 |
A novel technique for measuring human tissue pO2 at the cellular level.
Topics: Adult; Autoradiography; Carbon Radioisotopes; Humans; Male; Melanoma; Methods; Misonidazole; Oxygen Consumption; Skin Neoplasms; Tritium | 1986 |
A comparison of the tumour concentrations obtainable with misonidazole and Ro 03-8799.
Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cricetinae; Cricetulus; Female; Humans; Male; Melanoma; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1986 |
Influence of buthionine sulfoximine and misonidazole on glutathione level and radiosensitivity of human tumor xenografts.
Topics: Adenocarcinoma; Animals; Buthionine Sulfoximine; Cell Line; Colonic Neoplasms; Female; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Radiation Tolerance; Transplantation, Heterologous | 1986 |