Page last updated: 2024-08-22

misonidazole and Lung Neoplasms

misonidazole has been researched along with Lung Neoplasms in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (59.72)	18.7374
1990's	7 (9.72)	18.2507
2000's	4 (5.56)	29.6817
2010's	16 (22.22)	24.3611
2020's	2 (2.78)	2.80

Authors

Authors	Studies
Bourigault, P; Higgins, GS; Macpherson, RE; McGowan, DR; Skwarski, M	1
Calderoni, L; Castellucci, P; Fanti, S; Telo, S; Vichi, S; Zagni, F	1
Fenwick, JD; Gleeson, FV; Hackett, SL; Higgins, GS; Liu, D; Macpherson, RE; McGowan, DR; McKenna, WG	1
Huang, Y; Li, L; Liu, W; Lu, H; Wei, Y; Yu, J; Yu, Q; Yuan, S; Zhao, S; Zheng, J	1
Dong, M; Guo, S; Han, X; Li, G; Li, H; Lin, Y; Mi, Y; Ruan, Q; Wang, B; Xu, D; Zhang, X	1
Bradley, KM; Campo, L; Fenwick, JD; Gleeson, FV; Green, M; Higgins, GS; Horne, A; Macpherson, RE; Maughan, TS; McCole, MG; McGowan, DR; McKenna, WG; Mohammed, S; Muschel, RJ; Ng, SM; Panakis, N; Prevo, R; Skwarski, M; Strauss, VY; Stuart, R; Tacconi, EMC; Vallis, KA	1
Aide, N; Berriolo-Riedinger, A; Blagosklonov, O; Brenot-Rossi, I; Bridji, B; Cachin, F; Caignon, JM; Chaumet-Riffaud, P; Collombier, L; Courbon, F; Devillers, A; Doyeux, K; Dubray, B; Fernandez, P; Gremillet, E; Houzard, C; Kolesnikov-Gauthier, H; Modzelewski, R; Olivier, P; Roux, J; Tessonnier, L; Thureau, S; Vera, P; Vervueren, L	1
Carson, RE; Chan, C; Fung, EK; Jin, X; Liu, C; Mulnix, T; Naganawa, M	1
Arvold, ND; Heidari, P; Kunawudhi, A; Mahmood, U; Sequist, LV	1
Akula, MR; Bois, F; Carlson, DJ; Collier, L; Hammond, K; Huang, Y; Kabalka, GW; Kelada, OJ; Ropchan, J; Zheng, MQ	1
Francis, RJ; Lee, YC; Millward, MJ; Morandeau, L; Nowak, AK; Segal, A; Segard, T	1
Bradley, KM; Fenwick, JD; Gleeson, FV; Higgins, GS; Macpherson, RE; McGowan, DR	1
Cui, YL; Li, XF; Wang, X	1
Hu, X; Huang, Y; Wang, S; Wei, Y; Yu, J; Yu, Q; Yuan, S; Zhao, S; Zhao, W; Zhu, S	1
Bohn, P; Dubray, B; Edet-Sanson, A; Gardin, I; Hapdey, S; Ménard, JF; Modzelewski, R; Salles, A; Thiberville, L; Vera, P	1
Kong, FM; Meng, X; Yu, J	1
Civelek, AC; Huang, T; Jiang, H; Li, J; Li, XF; Ng, CK; Postel, GC; Shen, B	1
Askoxylakis, V; Bischof, M; Debus, J; Dimitrakopoulou-Strauss, A; Dinkel, J; Eichinger, M; Haberkorn, U; Huber, PE; Kopp-Schneider, A; Sommer, G; Stieltjes, B; Strauss, LG; Thieke, C	1
Bares, R; Dittmann, H; Eschmann, SM; Machulla, HJ; Paulsen, F; Reimold, M; Reischl, G; Welz, S	1
Asadpour, B; Buell, U; Coenen, HH; Demirel, C; Eble, MJ; Gagel, B; Hamacher, K; Kaiser, HJ; Pinkawa, M; Piroth, M; Reinartz, P; Stanzel, S; Zimny, M	1
Cherk, MH; Foo, SS; Knight, SR; Murone, C; O'Keefe, GJ; Papenfuss, AT; Poon, AM; Sachinidis, JI; Saunder, TH; Scott, AM	1
Lee, ST; Scott, AM	1
Hansen, HS; Hansen, JM; Kamieniecka, Z; Køhler, O; Melgaard, B; Paulson, OB; Pedersen, AG; Tang, X; Trojaborg, W	1
Heller, EH; Mameghan, H	1
Chaplin, DJ; Jinks, S; Millar, BC	1
Byhardt, RW; Cox, JD; Greenberg, M; Komaki, R	1
Hansen, HH; Kjaer, M; Panduro, J; Wolff-Jensen, J	1
Hunter, N; Ito, H; Milas, L	1
Onoyama, Y	1
Dar'ialova, SL; Kiseleva, ES	1
Clarke, C; Dawson, KB; Sheldon, PW; Simmons, DJ; Simpson, W	1
Irvin, CG; Nierenburg, M; Rockwell, S	1
Adams, GE; Ahmed, I; Chaplin, DJ; Sheldon, PW	1
Breccia, A; Busutti, L; Gattavecchia, E; Stagni, G	1
Mitsuhashi, N; Mogi, K; Nakajima, N; Niibe, H; Okazaki, A; Saito, K; Sakaino, K; Sudo, H; Suzuki, Y; Yonome, I	1
Asakura, H; Kanazawa, A; Maruhashi, A; Mashima, Y	1
Bleehen, NM; Jones, DH; Walton, MI; Workman, P	1
Abe, M; Dodo, Y; Ono, K; Takahashi, M	1
Abe, M; Dodo, Y; Hiraoka, M; Jo, S; Nishidai, T; Ono, K; Takahashi, M	1
Asakawa, H; Hoshino, T; Watarai, J	1
Kylmämaa, TT; Mäntylä, MJ; Nordman, EM; Ruotsalainen, PJ	1
Grdina, DJ; Mian, TA; Theiss, JC	1
Ash, DV	1
Carella, RJ; Concannon, JP; Perez, CA; Phillips, TL; Simpson, JR	1
Hansen, HS; Kamieniecka, Z; Melgaard, B; Paulson, OB; Pedersen, AG; Tang, X; Trojaborg, W	1
Kochanski, K; Siemann, DW	1
Courtenay, VD; Mills, J; Peacock, JH; Rose, CM; Spooner, D; Stephens, TC	1
Allalunis, MJ; Meeker, BE; Pedersen, JE; Turner, AR; Urtasun, RC	1
Bergman, KS; Evans, ML; Graham, MM; Grierson, JR; Koh, WJ; Krohn, KA; Lewellen, TK; Lindsley, KL; Peterson, LM; Rasey, JS	1
Cherif, A; Harrod, VL; Inoue, T; Kim, CG; Kim, EE; Kuang, LR; Newman, RA; Nornoo, A; Podoloff, DA; Wallace, S; Yang, DJ	1
Evans, ML; Graham, MM; Koh, WJ; Krohn, KA; Lewellen, TK; Peterson, LM; Rasey, JS	1
Bugden, RD; Peckham, MJ; Pedersen, JE; Smith, MR	1
Ash, DV; Peckham, MJ; Steel, GG	1
Bonomi, P; Faber, LP; Reddy, S	1
Asbell, S; Isaacson, S; Komarnicky, LT; Martz, K; Phillips, TL; Urtasun, R	1
Hall, EJ; Pirro, JP; Roizin-Towle, L	1
Butler, S; Cobb, LM; Nolan, J	1
Deacon, J; Holliday, S; Stratford, IJ; Walling, JM	1
Bauer, M; Byhardt, RW; Doggett, RL; Emami, B; Mowry, PA; Perez, CA; Phillips, TL; Simpson, JR; Wasserman, TH	1
Agrawal, KC; McNamara, DB; Shalinsky, DR	1
Chapman, JD; Kanclerz, A	1
Artim, RA; Carlson, RW; Coleman, CN; Gribble, M; Halsey, J; Kohler, M; Lawrence, HJ; Sampson, WI; Sikic, BI; Wong, P	1
Abe, M; Fushiki, M; Nishidai, T; Ono, K; Sasai, K; Shibamoto, Y; Takahashi, M; Tsutsui, K	1
Chapman, JD; Franko, AJ; Koch, CJ; Raleigh, JA; Urtasun, RC	1
Jakobsson, M; Kylmämaa, T; Taskinen, PJ	1
Bauer, M; Durbin, LM; Emami, B; Perez, CA; Simpson, JR; Wasserman, TH; Wiegensberg, I; Zinninger, M	1
Eady, JJ; Haslinger, RK; Peacock, JH; Schlappack, OK; Schmidt, WF	1
Chaplin, DJ	2
Acker, B; Chaplin, DJ	1
Chang, CH; Durbin, LM; Komaki, RU; Leibel, SA; Lipshutz, J; Massullo, V; Order, SE; Pajak, TF; Phillips, TL; Wasserman, TH	1
Abratt, RP; Hewitson, RH; Willcox, PA	1

Reviews

5 review(s) available for misonidazole and Lung Neoplasms

Article	Year
Alternative and New Radiopharmaceutical Agents for Lung Cancer. Current radiopharmaceuticals, 2020, Volume: 13, Issue:3 Topics: Acetates; Carbon Radioisotopes; Dideoxynucleosides; Fluorodeoxyglucose F18; Gallium Isotopes; Gallium Radioisotopes; Humans; Lung Neoplasms; Methionine; Misonidazole; Neoplasm Staging; Neuroendocrine Tumors; Peptides; Peptides, Cyclic; Positron Emission Tomography Computed Tomography; Quinolines; Radiopharmaceuticals; Sensitivity and Specificity	2020
Implementation of hypoxia measurement into lung cancer therapy. Lung cancer (Amsterdam, Netherlands), 2012, Volume: 75, Issue:2 Topics: Cell Hypoxia; Humans; Lung Neoplasms; Misonidazole; Oxygen; Positron-Emission Tomography; Prognosis; Radiosurgery	2012
Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole. Seminars in nuclear medicine, 2007, Volume: 37, Issue:6 Topics: Animals; Brain Ischemia; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Misonidazole; Myocardial Ischemia; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Stroke	2007
[Electron acceptor compounds as radiation sensitizers of hypoxic cells in human tumors]. Meditsinskaia radiologiia, 1984, Volume: 29, Issue:9 Topics: Brain Neoplasms; Combined Modality Therapy; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Metronidazole; Misonidazole; Mouth Neoplasms; Neoplasms; Radiation-Sensitizing Agents; Rectal Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms	1984
Concurrent chemotherapy and thoracic irradiation in non-small cell lung cancer. Hematology/oncology clinics of North America, 1990, Volume: 4, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined Modality Therapy; Drug Evaluation; Fluorouracil; Humans; Lung Neoplasms; Misonidazole; Neoplasm Metastasis; Prognosis; Radiotherapy; Radiotherapy Dosage; Survival Rate	1990

Trials

19 trial(s) available for misonidazole and Lung Neoplasms

Article	Year
Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma. European journal of cancer (Oxford, England : 1990), 2019, Volume: 113 Topics: Adenocarcinoma of Lung; Aged; Aminopyridines; Anorexia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemoradiotherapy; Fatigue; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Misonidazole; Morpholines; Nausea; Phosphoinositide-3 Kinase Inhibitors; Positron Emission Tomography Computed Tomography; Radiation-Sensitizing Agents; Radiotherapy; Tumor Hypoxia	2019
Interobserver agreement of qualitative analysis and tumor delineation of 18F-fluoromisonidazole and 3'-deoxy-3'-18F-fluorothymidine PET images in lung cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:9 Topics: Adult; Aged; Algorithms; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Misonidazole; Observer Variation; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tumor Burden	2013
A Comparative Study of Noninvasive Hypoxia Imaging with 18F-Fluoroerythronitroimidazole and 18F-Fluoromisonidazole PET/CT in Patients with Lung Cancer. PloS one, 2016, Volume: 11, Issue:6 Topics: Adult; Aged; Demography; Female; Humans; Hypoxia; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Tissue Distribution	2016
Multimodal hypoxia imaging and intensity modulated radiation therapy for unresectable non-small-cell lung cancer: the HIL trial. Radiation oncology (London, England), 2012, Sep-14, Volume: 7 Topics: Algorithms; Carcinoma, Non-Small-Cell Lung; Humans; Hypoxia; Lung Neoplasms; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Salvage Therapy; Tomography, X-Ray Computed; Treatment Outcome	2012
Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:2 Topics: Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Female; Fluorine Radioisotopes; Germany; Head and Neck Neoplasms; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome	2005
[18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography in response evaluation after chemo-/radiotherapy of non-small-cell lung cancer: a feasibility study. BMC cancer, 2006, Mar-04, Volume: 6 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Combined Modality Therapy; Deoxycytidine; Feasibility Studies; Female; Fluorodeoxyglucose F18; Gemcitabine; Glucose; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Misonidazole; Positron-Emission Tomography; Prospective Studies; Pulmonary Embolism; Radiopharmaceuticals; Treatment Outcome; Vinblastine; Vinorelbine	2006
Misonidazole neuropathy. Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100 Topics: Aged; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nerves; Peripheral Nervous System Diseases; Pharyngeal Neoplasms	1984
Misonidazole combined with radiotherapy in the treatment of inoperable squamous cell carcinoma of the lung. A double-blind randomized trial. Cancer, 1983, Jul-01, Volume: 52, Issue:1 Topics: Aged; Carcinoma, Squamous Cell; Double-Blind Method; Esophagitis; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Placebos; Pneumonia; Radiation Injuries; Radiotherapy Dosage; Random Allocation; Vomiting	1983
[Clinical trials of hypoxic cell sensitizer misonidazole]. Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:6 Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Evaluation; Female; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Random Allocation; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms	1983
[Biological and physical approach to the improvement of radiotherapy]. Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:13 Topics: Animals; Cell Survival; Hot Temperature; Humans; Lung Neoplasms; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiotherapy	1983
[Clinical evaluation of hypoxic cell sensitizer (Misonidazole)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:6 Topics: Aged; Esophageal Neoplasms; Female; Humans; Kidney; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Oxygen; Stomach Neoplasms; Tongue Neoplasms; Uterine Cervical Neoplasms	1984
Misonidazole and radiotherapy in lung cancer: a randomized double-blind trial. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:10 Topics: Aged; Carcinoma, Bronchogenic; Clinical Trials as Topic; Double-Blind Method; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Random Allocation	1982
Concurrent chemotherapy and thoracic irradiation in non-small cell lung cancer. Hematology/oncology clinics of North America, 1990, Volume: 4, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined Modality Therapy; Drug Evaluation; Fluorouracil; Humans; Lung Neoplasms; Misonidazole; Neoplasm Metastasis; Prognosis; Radiotherapy; Radiotherapy Dosage; Survival Rate	1990
A randomized phase III protocol for the evaluation of misonidazole combined with radiation in the treatment of patients with brain metastases (RTOG-7916). International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:1 Topics: Adenocarcinoma; Adult; Aged; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Prospective Studies; Radiation-Sensitizing Agents; Survival Analysis	1991
Radiation therapy alone or combined with misonidazole in the treatment of locally advanced non-oat cell lung cancer: report of an RTOG prospective randomized trial. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:6 Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Lung Neoplasms; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prognosis; Prospective Studies; Random Allocation	1989
Enhancement of the clinical activity of melphalan by the hypoxic cell sensitizer misonidazole. Cancer research, 1988, Jun-15, Volume: 48, Issue:12 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Melphalan; Middle Aged; Misonidazole	1988
Misonidazole combined with radiotherapy in the treatment of non-small cell lung cancer. A randomized double-blind trial. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1987, Volume: 163, Issue:2 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation	1987
Large fraction irradiation with or without misonidazole in advanced non-oat cell carcinoma of the lung: a phase III randomized trial of the RTOG. Radiation Therapy Oncology Group. International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:6 Topics: Adolescent; Adult; Aged; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation	1987
A comparison of misonidazole sensitized radiation therapy to radiation therapy alone for the palliation of hepatic metastases: results of a Radiation Therapy Oncology Group randomized prospective trial. International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:7 Topics: Alkaline Phosphatase; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Misonidazole; Prognosis	1987

Other Studies

49 other study(ies) available for misonidazole and Lung Neoplasms

Article	Year
Timing of hypoxia PET/CT imaging after 18F-fluoromisonidazole injection in non-small cell lung cancer patients. Scientific reports, 2022, 12-16, Volume: 12, Issue:1 Topics: Atovaquone; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Humans; Hypoxia; Lung Neoplasms; Misonidazole; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals	2022
Medical physics, 2017, Volume: 44, Issue:9 Topics: Bayes Theorem; Carcinoma, Non-Small-Cell Lung; Humans; Kinetics; Lung Neoplasms; Misonidazole; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals	2017
To Explore a Representative Hypoxic Parameter to Predict the Treatment Response and Prognosis Obtained by [ Molecular imaging and biology, 2018, Volume: 20, Issue:6 Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Female; Humans; Hypoxia; Kaplan-Meier Estimate; Logistic Models; Lung Neoplasms; Male; Middle Aged; Misonidazole; Progression-Free Survival; Proportional Hazards Models; Treatment Outcome	2018
Dosimetry study of Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018, Volume: 20, Issue:10 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Humans; Hypoxia; Lung Neoplasms; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron Emission Tomography Computed Tomography; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated	2018
Event-by-event respiratory motion correction for PET with 3D internal-1D external motion correlation. Medical physics, 2013, Volume: 40, Issue:11 Topics: Carcinoma, Non-Small-Cell Lung; Fluorine Radioisotopes; Healthy Volunteers; Humans; Hypoxia; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Insulin-Secreting Cells; Kidney; Lung Neoplasms; Misonidazole; Movement; Pancreas; Positron-Emission Tomography; Regression Analysis; Reproducibility of Results; Respiration; Signal Processing, Computer-Assisted; Tetrabenazine; X-Ray Microtomography	2013
Tumor Hypoxia Response After Targeted Therapy in EGFR-Mutant Non-Small Cell Lung Cancer: Proof of Concept for FMISO-PET. Technology in cancer research & treatment, 2016, Volume: 15, Issue:2 Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; Mice, Nude; Misonidazole; Molecular Targeted Therapy; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Xenograft Model Antitumor Assays	2016
Synthesis of [(18)F]FMISO in a flow-through microfluidic reactor: Development and clinical application. Nuclear medicine and biology, 2015, Volume: 42, Issue:6 Topics: Adenocarcinoma; Aged; Carcinoma, Non-Small-Cell Lung; Fluorine Radioisotopes; Humans; Hypoxia; Image Processing, Computer-Assisted; Lung Neoplasms; Male; Microfluidics; Misonidazole; Pilot Projects; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiochemistry; Tissue Distribution	2015
Characterization of hypoxia in malignant pleural mesothelioma with FMISO PET-CT. Lung cancer (Amsterdam, Netherlands), 2015, Volume: 90, Issue:1 Topics: Aged; Aged, 80 and over; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Middle Aged; Misonidazole; Pilot Projects; Pleural Neoplasms; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiopharmaceuticals; Tomography, X-Ray Computed	2015
18F-Misonidazole PET-CT scan detection of occult bone metastasis. Thorax, 2016, Volume: 71, Issue:1 Topics: Aged; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Diagnosis, Differential; Humans; Lung Neoplasms; Male; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed	2016
(18)F-fluoromisonidazole PET reveals spatial and temporal heterogeneity of hypoxia in mouse models of human non-small-cell lung cancer. Future oncology (London, England), 2015, Volume: 11, Issue:20 Topics: Animals; Autoradiography; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Disease Models, Animal; Heterografts; Humans; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Nude; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals	2015
Simultaneous positron emission tomography (PET) assessment of metabolism with ¹⁸F-fluoro-2-deoxy-d-glucose (FDG), proliferation with ¹⁸F-fluoro-thymidine (FLT), and hypoxia with ¹⁸fluoro-misonidazole (F-miso) before and during radiotherapy in patients wit Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 98, Issue:1 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed	2011
Tumor microenvironment-dependent 18F-FDG, 18F-fluorothymidine, and 18F-misonidazole uptake: a pilot study in mouse models of human non-small cell lung cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:8 Topics: Animals; Biological Transport; Bromodeoxyuridine; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Disease Models, Animal; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Mice; Misonidazole; Necrosis; Nitroimidazoles; Pilot Projects; Positron-Emission Tomography; Radioactive Tracers; Tumor Microenvironment	2012
Lack of correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in non-small cell lung cancer assessed by 18F-Fluoromisonidazole and 18F-FDG PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:12 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Fluorodeoxyglucose F18; Glucose; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Misonidazole; Neovascularization, Pathologic; Radionuclide Imaging; Radiopharmaceuticals; Statistics as Topic	2006
Misonidazole & radiotherapy in the palliative treatment of lung cancer. Australasian radiology, 1983, Volume: 27, Issue:3 Topics: Administration, Oral; Aged; Carcinoma, Bronchogenic; Drug Evaluation; Female; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Palliative Care	1983
Studies on the protection against misonidazole-induced toxicity by antiinflammatory agents. Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 12 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dexamethasone; Female; Flurbiprofen; Lung; Lung Neoplasms; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Phospholipases; Phospholipases A; Propionates	1983
Reduced fractionation and the potential of hypoxic cell sensitizers in irradiation of malignant epithelial tumors. International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:1 Topics: Adenocarcinoma; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Misonidazole; Mouth Neoplasms; Nitroimidazoles; Oropharynx; Pharyngeal Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Retrospective Studies	1980
Effect of tumor size on S-2-(3-aminopropylamino)ethylphosphorothioic acid and misonidazole alteration of tumor response to cyclophosphamide. Cancer research, 1983, Volume: 43, Issue:7 Topics: Amifostine; Animals; Cyclophosphamide; Drug Interactions; Drug Therapy, Combination; Extremities; Female; Fibrosarcoma; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Organothiophosphorus Compounds; Time Factors	1983
Intestinal microflora as potential modifiers of sensitizer activity in vivo. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Bacteria; Body Temperature; Combined Modality Therapy; Drug Synergism; Female; Intestines; Lung Neoplasms; Melphalan; Mice; Misonidazole; Nitroimidazoles; Penicillins; Radiation-Sensitizing Agents	1984
Enhancement of artificial lung metastases by misonidazole. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Cell Line; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Potentiation of cyclophosphamide cytotoxicity in vivo: a study with misonidazole and fifteen other 1-substituted 2-nitroimidazoles. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1984
Clinical trials with cyclophosphamide and misonidazole combination for maintaining treatment after radiation therapy of lung carcinoma. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Adult; Aged; Combined Modality Therapy; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1984
[Clinical evaluation of radiosensitizing effects of misonidazole]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1984, Jul-25, Volume: 44, Issue:7 Topics: Brain Neoplasms; Combined Modality Therapy; Drug Evaluation; Esophageal Neoplasms; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles	1984
[Radiotherapy in combination with misonidazole and ACNU in lung neoplasms]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1983, Nov-25, Volume: 43, Issue:11 Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nimustine; Nitroimidazoles; Nitrosourea Compounds; Radiotherapy Dosage	1983
The role of dexamethasone in the modification of misonidazole pharmacokinetics. British journal of cancer, 1983, Volume: 48, Issue:4 Topics: Adult; Aged; Dexamethasone; Drug Interactions; Female; Humans; Kinetics; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Misonidazole; Nitroimidazoles; Phenobarbital; Phenytoin	1983
[Clinical study on radiotherapy in combination with misonidazole]. Nihon Gan Chiryo Gakkai shi, 1983, Aug-20, Volume: 18, Issue:5 Topics: Aged; Esophageal Neoplasms; Female; Humans; Lung Neoplasms; Middle Aged; Misonidazole; Neoplasms; Nitroimidazoles; Pharyngeal Neoplasms; Radiation-Sensitizing Agents	1983
Lung tumorigenic response of strain A mice exposed to hypoxic cell sensitizers alone and in combination with gamma-radiation. Cancer research, 1983, Volume: 43, Issue:1 Topics: Adenoma; Animals; Hypoxia; Lung; Lung Neoplasms; Metronidazole; Mice; Mice, Inbred A; Misonidazole; Neoplasms, Radiation-Induced; Radiation-Sensitizing Agents	1983
Growth delay studies in patients with multiple metastases. The British journal of cancer. Supplement, 1980, Volume: 4 Topics: Clinical Trials as Topic; Follow-Up Studies; Humans; Lung Neoplasms; Misonidazole; Time Factors	1980
Large fraction radiotherapy plus misonidazole for treatment of advanced lung cancer: report of a phase I/II trial. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:2 Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Radiotherapy; Radiotherapy Dosage	1982
Misonidazole Neuropathy: a clinical, electrophysiological, and histological study. Annals of neurology, 1982, Volume: 12, Issue:1 Topics: Aged; Carcinoma, Squamous Cell; Electromyography; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Median Nerve; Middle Aged; Misonidazole; Nerve Fibers, Myelinated; Nervous System Diseases; Neural Conduction; Neuromuscular Diseases; Nitroimidazoles; Paresthesia; Peroneal Nerve; Pharyngeal Neoplasms; Sensation; Sural Nerve; Tibial Nerve	1982
Combinations of radiation and misonidazole in a murine lung tumor model. Radiation research, 1981, Volume: 86, Issue:2 Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Female; Lung; Lung Neoplasms; Mice; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radiotherapy; Sarcoma, Experimental; Time Factors	1981
Enhanced cell killing in lewis lung carcinoma and a human pancreatic-carcinoma xenograft by the combination of cytotoxic drugs and misonidazole. British journal of cancer, 1981, Volume: 43, Issue:4 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Pancreatic Neoplasms; Transplantation, Heterologous	1981
Cytotoxic and radiosensitizing effects of misonidazole on hematopoiesis in normal and tumor-bearing mice. International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:9 Topics: Animals; Colony-Forming Units Assay; Dose-Response Relationship, Radiation; Hematopoiesis; Hematopoietic Stem Cells; Hypoxia; Lung Neoplasms; Male; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles	1980
Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography. International journal of radiation oncology, biology, physics, 1995, Sep-30, Volume: 33, Issue:2 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Oxygen Consumption; Radiation-Sensitizing Agents; Tomography, Emission-Computed	1995
Development of new markers for hypoxic cells: [131I]Iodomisonidazole and [131I]Iodoerythronitroimidazole. Journal of drug targeting, 1996, Volume: 4, Issue:1 Topics: Animals; Breast Neoplasms; Cell Hypoxia; Female; Iodine Radioisotopes; Lung Neoplasms; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Radionuclide Imaging; Rats; Rats, Inbred F344; Tissue Distribution; Tumor Cells, Cultured	1996
Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: a pretherapy study of 37 patients. International journal of radiation oncology, biology, physics, 1996, Sep-01, Volume: 36, Issue:2 Topics: Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Fluorine Radioisotopes; Humans; Lung Neoplasms; Male; Misonidazole; Neoplasms; Prostatic Neoplasms; Tomography, Emission-Computed	1996
Distribution and tumour cytotoxicity of the radiosensitizer misonidazole (Ro-07-0582) in C57 mice. British journal of cancer, 1979, Volume: 39, Issue:4 Topics: Animals; Cell Survival; Guinea Pigs; Lung Neoplasms; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Tissue Distribution	1979
The quantitative response of human tumours to radiation and misonidazole. British journal of cancer, 1979, Volume: 40, Issue:6 Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Radiation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Skin Neoplasms	1979
Studies with bifunctional bioreductive drugs. II. Cytotoxicity assayed with A-549 lung carcinoma cells of human origin. Radiation research, 1990, Volume: 124, Issue:1 Suppl Topics: Antineoplastic Agents; Aziridines; Cell Line; Cell Survival; Humans; In Vitro Techniques; Lung Neoplasms; Misonidazole; Nitrofurans; Radiation-Sensitizing Agents	1990
Tissue distribution of 14C- and 3H-labelled misonidazole in the tumor-bearing mouse. International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:2 Topics: Adenocarcinoma; Animals; Carbon Radioisotopes; Female; Lung Neoplasms; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Tissue Distribution; Tritium	1990
High uptake of RSU 1069 and its analogues melanotic melanomas. Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:1 Topics: Animals; Cell Line; Cell Membrane Permeability; Deoxyribonucleases; Drug Evaluation, Preclinical; Half-Life; Humans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Microbial Collagenase; Misonidazole; Sarcoma, Experimental; Tissue Distribution; Trypsin; Tumor Cells, Cultured	1989
Modulation of prostaglandin biosynthesis in hypoxic murine mammary adenocarcinoma cells by misonidazole. Cancer research, 1989, Jul-15, Volume: 49, Issue:14 Topics: Adenocarcinoma; Anaerobiosis; Animals; Cell Line; Hypoxia; Indomethacin; Kinetics; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Misonidazole; Prostaglandins; Tumor Cells, Cultured	1989
Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice. International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:2 Topics: Amifostine; Animals; Etanidazole; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Metastasis; Neoplasms, Experimental; Nitroimidazoles; Radiation-Protective Agents; Radiation-Sensitizing Agents	1988
[Present status of hypoxic cell sensitizers and PLDR inhibitors]. Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:13 Topics: Animals; Cell Cycle; Cell Line; Etanidazole; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy Dosage	1987
Binding of 3H-misonidazole to solid human tumors as a measure of tumor hypoxia. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Autoradiography; Carcinoma, Small Cell; Humans; Lung Neoplasms; Melanoma; Misonidazole; Neoplasms; Oxygen; Tritium	1986
Lack of radiosensitization in Lewis lung carcinoma and a murine plasmacytoma by MTDQ and MTDQ-DA. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1988, Volume: 164, Issue:11 Topics: Animals; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Misonidazole; Plasmacytoma; Quinolines; Radiation-Sensitizing Agents; Radiotherapy Dosage	1988
Postirradiation modification of tumor blood flow: a method to increase the effectiveness of chemical radiosensitizers. Radiation research, 1988, Volume: 115, Issue:2 Topics: Animals; Cell Survival; Combined Modality Therapy; Female; Hydralazine; Lung Neoplasms; Mice; Mice, Inbred C57BL; Misonidazole; Radiation-Sensitizing Agents; Regional Blood Flow; Vasodilator Agents	1988
The effect of hydralazine on the tumor cytotoxicity of the hypoxic cell cytotoxin RSU-1069: evidence for therapeutic gain. International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:4 Topics: Animals; Cell Survival; Cells, Cultured; Female; Hydralazine; Lung Neoplasms; Mice; Mice, Inbred C57BL; Misonidazole; Radiation-Sensitizing Agents	1987
Radical irradiation of localized inoperable lung cancer with concurrent chemotherapy and misonidazole: a phase I/II study. European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:7 Topics: Combined Modality Therapy; Drug Evaluation; Humans; Lung Neoplasms; Misonidazole	1987
Potentiation of RSU-1069 tumour cytotoxicity by 5-hydroxytryptamine (5-HT). British journal of cancer, 1986, Volume: 54, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Lung Neoplasms; Mice; Mice, Inbred C57BL; Misonidazole; Serotonin	1986