Page last updated: 2024-08-22

misonidazole and Glioma

misonidazole has been researched along with Glioma in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199025 (51.02)18.7374
1990's5 (10.20)18.2507
2000's4 (8.16)29.6817
2010's15 (30.61)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barré, L; Bekaert, L; Bernaudin, M; Bordji, K; Branger, P; Collet, S; Constans, JM; Emery, E; Guillamo, JS; Lechapt-Zalcman, E; Levallet, G; Manrique, A; Petit, E; Ponte, K; Valable, S1
Al Jaberi, M; Förster, S; Gempt, J; Göttler, J; Kluge, A; Lukas, M; Meyer, B; Preibisch, C; Pyka, T; Ringel, F; Schlegel, J; Shi, K; Wiestler, B; Zimmer, C1
Hirata, K; Houkin, K; Kobayashi, H; Shiga, T; Terasaka, S; Yamaguchi, S1
Cao, WD; Haba, R; Kawai, N; Lin, W; Maeda, Y; Miyake, K; Nishiyama, Y; Ogawa, D; Tamiya, T; Yamamoto, Y1
Hawkins-Daarud, AJ; Hendrickson, K; Jacobs, J; Kinahan, P; Krohn, KA; Mrugala, MM; Neal, ML; Rockhill, JK; Rockne, RC; Swanson, KR; Trister, AD1
Bell, C; Dowson, N; Fay, M; Gal, Y; Puttick, S; Rose, S; Thomas, P1
Chen, J; Fan, D; Qian, J; Wang, F; Zhang, Z; Zhu, J1
Wang, H; Xu, H; Xue, Y; Yu, W; Zhang, Y; Zhao, X1
Hirata, K; Houkin, K; Ishi, Y; Kobayashi, H; Kobayashi, K; Motegi, H; Shiga, T; Tamaki, N; Terasaka, S; Toyonaga, T; Yamaguchi, S1
Alessio, AM; Alvord, EC; Anderson, AR; Chakraborty, G; Champley, K; Claridge, J; Gu, S; Kinahan, PE; Krohn, KA; Muzi, M; Rockne, R; Spence, AM; Swanson, KR1
Barré, L; Bernaudin, M; Delamare, J; Divoux, D; Marteau, L; Petit, E; Roussel, S; Sobrio, F; Toutain, J; Valable, S1
Hattori, N; Hirata, K; Houkin, K; Kobayashi, H; Kuge, Y; Magota, K; Shiga, T; Tamaki, N; Tanaka, S; Terasaka, S; Yamaguchi, S1
Aga, F; Kawai, N; Kudomi, N; Maeda, Y; Nishiyama, Y; Ono, Y; Yamamoto, Y1
Hanzawa, H; Hatano, T; Kuge, Y; Kuno, N; Nishijima, K; Sakamoto, T; Tamaki, N; Zhao, S; Zhao, Y1
Barré, L; Bernaudin, M; Corroyer-Dulmont, A; Divoux, D; Durand, L; MacKenzie, ET; Marteau, L; Pérès, EA; Petit, E; Roussel, S; Toutain, J; Valable, S1
Berlangieri, SU; Cher, LM; Fabinyi, G; Hannah, A; Lawrentschuk, N; Murone, C; O'Keefe, GJ; Papenfuss, A; Ramdave, S; Sachinidis, JI; Scott, AM1
Lee, ST; Scott, AM1
Allen, J; Edwards, MS; Levin, VA; Ortega, J; Vestnys, P; Wara, WM1
Fulton, DS; Geggie, PH; Johnson, E; Mielke, B; Moody, J; Muller, PJ; Shin, KH; Tanasichuk, H; Thomas, H; Urtasun, RC1
Handa, H; Oda, Y; Ono, K; Otsuka, S; Suda, K; Takeuchi, J; Yamashita, J; Yumitori, K1
Strike, TA; Walker, MD1
Carabell, S; Goodman, RL; Nelson, DF; Nelson, JS; Schoenfeld, D; Wasserman, T; Weinstein, AS1
Onoyama, Y1
Davis, DR; Diener, MD; Gillespie, BW; Nelson, DF; Phillips, TL; Stetz, J; Wasserman, T1
Gi, H; Handa, H; Oda, Y; Ono, K; Otsuka, S; Suda, K; Takeuchi, J; Yamashita, J1
Ang, KK; Chenal, C; Fauchon, F; Goffin, JC; Horiot, JC; Notter, G; Raps, J; van der Schueren, E; van Glabbeke, M; van Peperzeel, H; Vessière, M1
Bleehen, NM1
Bamberg, M; Scherer, E; Streffer, C; Tamulevicius, P2
Phillips, TL; Stetz, J; Wasserman, TH1
Barcellos, MH; Bernstein, M; Deen, DF; Gutin, PH; Sano, Y; Shrieve, DC1
Otsuka, S1
Bruno, LA; Carabell, SC; Chang, CH; Goodman, RL; Richter, MP; Weiler, CB; Weinstein, AS1
Allalunis-Turner, MJ; Franko, AJ; Mercer, JR; Mielke, BW; Parliament, MB; Santos, CL; Wolokoff, BG1
Allalunis-Turner, MJ; Franko, AJ; Parliament, MB; Wolokoff, BG1
Chin, LK; Hofstrand, PD; Rasey, JS; Tewson, TJ1
Casciari, JJ; Chin, LK; Graham, MM; Hofstrand, PD; Muzi, M; Rasey, JS1
Chan, F; Chan, JG; Cher, L; Hall, C; Hill, J; Kaye, A; Sachinidis, JI; Scott, AM; Stylli, S; Tochon-Danguy, HJ1
Bataini, JP; Bernier, J; Brugère, J; Brunin, F; de Narbonne, J; Jaulerry, C1
Boisvert, DP; Franko, AJ; Koch, CJ1
Burger, PC; Deutsch, M; Green, SB; Mealey, J; Paoletti, P; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Strike, TA1
Arai, M; Hayakawa, K; Niibe, H; Tamura, M1
Fulton, DS; McKinnon, S; Tanasichuk, H; Urtasun, RC1
Gutin, PH; Nelson, DF; Saunders, WM; Sheline, GE; Urtasun, RC1
Diener-West, M; Nelson, DF; Pakuris, E; Weinstein, AS1
Carabell, S; Chang, CH; Diener-West, M; Goodman, R; Nelson, DF; Nelson, JS; Sause, WT; Schoenfeld, D; Weinstein, AS1
Inoue, H; Koizumi, H; Murata, M; Nakamura, M; Niibe, H; Tamura, M; Yonome, I1

Reviews

4 review(s) available for misonidazole and Glioma

ArticleYear
Usefulness of FMISO-PET for glioma analysis.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Adult; Animals; Brain Neoplasms; Diagnosis, Differential; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Misonidazole; Oxygen; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results

2013
Hypoxia imaging in gliomas with 18F-fluoromisonidazole PET: toward clinical translation.
    Seminars in nuclear medicine, 2015, Volume: 45, Issue:2

    Topics: Animals; Cell Hypoxia; Glioma; Humans; Misonidazole; Positron-Emission Tomography; Translational Research, Biomedical; Treatment Failure

2015
Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole.
    Seminars in nuclear medicine, 2007, Volume: 37, Issue:6

    Topics: Animals; Brain Ischemia; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Misonidazole; Myocardial Ischemia; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Stroke

2007
Recent and current investigations of radiation therapy of malignant gliomas.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Brachytherapy; Brain; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Glioma; Helium; Humans; Hyperbaric Oxygenation; Hyperthermia, Induced; Mesons; Metronidazole; Middle Aged; Misonidazole; Neon; Neutrons; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy, High-Energy

1986

Trials

16 trial(s) available for misonidazole and Glioma

ArticleYear
[18F]-FMISO PET study of hypoxia in gliomas before surgery: correlation with molecular markers of hypoxia and angiogenesis.
    European journal of nuclear medicine and molecular imaging, 2017, Volume: 44, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Biomarkers, Tumor; Brain Neoplasms; Cerebral Blood Volume; Disease-Free Survival; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Neovascularization, Pathologic; Positron-Emission Tomography; Radiosurgery; Tumor Hypoxia

2017
¹⁸F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas.
    European journal of nuclear medicine and molecular imaging, 2012, Volume: 39, Issue:5

    Topics: Adult; Aged; Anaplasia; Biological Transport; Brain Neoplasms; Diagnosis, Differential; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Misonidazole; Neoplasm Grading; Positron-Emission Tomography

2012
Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:3

    Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Glioma; Glucose; Humans; Male; Metabolic Clearance Rate; Middle Aged; Misonidazole; Neovascularization, Pathologic; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Statistics as Topic

2006
Misonidazole combined with hyperfractionation in the management of malignant glioma.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Glioblastoma; Glioma; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy Dosage; Random Allocation

1984
Misonidazole in radiotherapy of supratentorial malignant brain gliomas in adult patients: a randomized double-blind study.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:1

    Topics: Adult; Brain Neoplasms; Clinical Trials as Topic; Double-Blind Method; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Prognosis; Radiotherapy Dosage; Time Factors

1983
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study.
    International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Glioma; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation

1983
[Clinical trials of hypoxic cell sensitizer misonidazole].
    Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:6

    Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Evaluation; Female; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Random Allocation; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms

1983
Is misonidazole neurotoxicity altered by the use of phenytoin and/or dexamethasone in RTOG 79-18 and RTOG 79-16?
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dexamethasone; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Phenytoin; Radiation-Sensitizing Agents

1984
The Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies.
    Cancer clinical trials, 1980,Fall, Volume: 3, Issue:3

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Glioma; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Phenobarbital; Phenytoin; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

1980
Misonidazole as a radiosensitizer in the radiotherapy of glioblastomas and oesophageal cancer. Pharmacokinetic and clinical studies.
    The British journal of radiology, 1981, Volume: 54, Issue:640

    Topics: Adult; Aged; Brain Neoplasms; Clinical Trials as Topic; Esophageal Neoplasms; Female; Glioma; Humans; Kinetics; Male; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles

1981
Radiation Therapy Oncology Group clinical trials with misonidazole.
    Cancer, 1981, May-15, Volume: 47, Issue:10

    Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Administration Schedule; Glioma; Head and Neck Neoplasms; Humans; Misonidazole; Nausea; Nervous System Diseases; Nitroimidazoles; Radiotherapy Dosage; Random Allocation; Vomiting

1981
[Clinical testing of the radiosensitizer RO-07-0582 (misonidazole). Dose tolerance, toxicity and pharmacokinetic studies, preliminary report (author's transl)].
    Bulletin du cancer, 1978, Volume: 65, Issue:4

    Topics: Bone Neoplasms; Clinical Trials as Topic; Glioma; Humans; Kinetics; Misonidazole; Neoplasms; Nitroimidazoles; Otorhinolaryngologic Diseases; Sarcoma

1978
Prognostic factors for high-grade malignant glioma: development of a prognostic index. A Report of the Medical Research Council Brain Tumour Working Party.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Multivariate Analysis; Prognosis; Proportional Hazards Models

1990
Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Astrocytoma; Carmustine; Combined Modality Therapy; Glioblastoma; Glioma; Humans; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prognosis; Radiotherapy Dosage; Random Allocation; Streptozocin; Supratentorial Neoplasms

1989
Pulmonary toxicity of carmustine in patients treated for malignant glioma.
    Cancer treatment reports, 1986, Volume: 70, Issue:8

    Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Glioma; Humans; Lung Diseases; Male; Middle Aged; Misonidazole; Random Allocation; Risk

1986
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:10

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Glioma; Humans; Middle Aged; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation

1986

Other Studies

29 other study(ies) available for misonidazole and Glioma

ArticleYear
Characterizing hypoxia in human glioma: A simultaneous multimodal MRI and PET study.
    NMR in biomedicine, 2017, Volume: 30, Issue:11

    Topics: Aged; Brain Neoplasms; Cell Hypoxia; Female; Glioma; Humans; Image Enhancement; Immunohistochemistry; Magnetic Resonance Imaging; Male; Middle Aged; Misonidazole; Positron-Emission Tomography

2017
Correlation between ¹⁸F-fluoromisonidazole PET and expression of HIF-1α and VEGF in newly diagnosed and recurrent malignant gliomas.
    European journal of nuclear medicine and molecular imaging, 2014, Volume: 41, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; Female; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Vascular Endothelial Growth Factor A

2014
A patient-specific computational model of hypoxia-modulated radiation resistance in glioblastoma using 18F-FMISO-PET.
    Journal of the Royal Society, Interface, 2015, Feb-06, Volume: 12, Issue:103

    Topics: Aged; Brain Neoplasms; Glioma; Humans; Hypoxia; Male; Misonidazole; Models, Biological; Positron-Emission Tomography; Precision Medicine; Radiation-Sensitizing Agents; Radiography

2015
Preparation and Biodistribution of Technetium-99m-Labeled Bis- Misonidazole (MISO) as an Imaging Agent for Tumour Hypoxia.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2015, Volume: 11, Issue:7

    Topics: Animals; Autoradiography; Cell Hypoxia; Glioma; Male; Mice; Mice, Inbred ICR; Misonidazole; Oils; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Water

2015
Radiosensitizing effect of irisquinone on glioma through the downregulation of HIF-1α evaluated by 18F-FDG and 18F-FMISO PET/CT.
    Nuclear medicine communications, 2016, Volume: 37, Issue:7

    Topics: Animals; Benzoquinones; Cell Line, Tumor; Down-Regulation; Fluorodeoxyglucose F18; Glioma; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Misonidazole; Positron Emission Tomography Computed Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tumor Hypoxia

2016
Change in 18F-Fluoromisonidazole PET Is an Early Predictor of the Prognosis in the Patients with Recurrent High-Grade Glioma Receiving Bevacizumab Treatment.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Glioma; Humans; Magnetic Resonance Imaging; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Retrospective Studies

2016
Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images.
    Mathematical medicine and biology : a journal of the IMA, 2012, Volume: 29, Issue:1

    Topics: Adult; Brain Neoplasms; Cell Proliferation; Computer Simulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Mathematical Concepts; Misonidazole; Models, Biological; Necrosis; Neoplasm Invasiveness; Neovascularization, Pathologic; Positron-Emission Tomography; Precision Medicine; Radiopharmaceuticals; User-Computer Interface

2012
Complementary information from magnetic resonance imaging and (18)F-fluoromisonidazole positron emission tomography in the assessment of the response to an antiangiogenic treatment in a rat brain tumor model.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Biological Transport; Brain; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cerebrovascular Circulation; Disease Models, Animal; Glioma; Indoles; Kinetics; Magnetic Resonance Imaging; Misonidazole; Neovascularization, Pathologic; Permeability; Positron-Emission Tomography; Pyrroles; Rats; Sunitinib; Treatment Outcome

2011
Hypoxia assessed by 18F-fluoromisonidazole positron emission tomography in newly diagnosed gliomas.
    Nuclear medicine communications, 2012, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Hypoxia; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiation-Sensitizing Agents; Retrospective Studies; Young Adult

2012
Biological characteristics of intratumoral [F-18]‑fluoromisonidazole distribution in a rodent model of glioma.
    International journal of oncology, 2013, Volume: 42, Issue:3

    Topics: Animals; Autoradiography; Biological Transport; Brain Neoplasms; Cell Hypoxia; Cell Proliferation; Fluorodeoxyglucose F18; Glioma; Glucose; Glucose Transporter Type 1; Hexokinase; Hypoxia-Inducible Factor 1; Ki-67 Antigen; Male; Misonidazole; Nitroimidazoles; Rats; Rats, Wistar; Tissue Distribution

2013
Noninvasive assessment of hypoxia with 3-[18F]-fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([18F]-FMISO): a PET study in two experimental models of human glioma.
    Biological chemistry, 2013, Volume: 394, Issue:4

    Topics: Glioma; Humans; Hypoxia; Immunohistochemistry; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Misonidazole; Positron-Emission Tomography

2013
5-Fluorouracil and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) followed by hydroxyurea, misonidazole, and irradiation for brain stem gliomas: a pilot study of the Brain Tumor Research Center and the Childrens Cancer Group.
    Neurosurgery, 1984, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Lomustine; Male; Misonidazole; Prognosis; Radioisotope Teletherapy

1984
[Radiosensitizing effect of misonidazole on intracranially transplanted tumors in mice and its clinical application (author's transl)].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:5

    Topics: Adult; Aged; Animals; Brain Neoplasms; Cobalt Radioisotopes; Female; Glioma; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage

1982
Misonidazole peripheral neuropathy: its relationship to plasma concentration and other drugs.
    Cancer clinical trials, 1980,Summer, Volume: 3, Issue:2

    Topics: Adrenal Cortex Hormones; Barbiturates; Brain Neoplasms; Drug Interactions; Female; Glioma; Half-Life; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Phenytoin

1980
[Local administration of radiosensitizer misonidazole].
    No to shinkei = Brain and nerve, 1983, Volume: 35, Issue:3

    Topics: Adult; Aged; Animals; Astrocytoma; Brain Neoplasms; Dogs; Drug Implants; Female; Glioma; Humans; Injections, Spinal; Kinetics; Male; Mice; Mice, Inbred C57BL; Misonidazole; Nitroimidazoles; Rats; Silicone Elastomers; Uterine Neoplasms

1983
Split course multiple daily fractionated radiotherapy schedule combined with misonidazole for the management of grade III and IV gliomas. A pilot feasibility study of the Radiotherapy Group of the EORTC.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:10

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prognosis; Radiotherapy Dosage; Radiotherapy, High-Energy

1982
Further evidence for the absence of a hypoxic fraction in the 9L rat tumour multicellular spheroid system.
    The British journal of radiology, 1982, Volume: 55, Issue:657

    Topics: Animals; Cell Survival; Glioma; Misonidazole; Neoplasms, Experimental; Oxygen; Rats

1982
[Radiosensitizing effect of misonidazole in radiotherapy for intracranial tumors].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1982, Nov-01, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Child; Drug Implants; Female; Glioma; Humans; Male; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Silicone Elastomers

1982
Misonidazole and radiotherapy to treat malignant glioma: a phase II trial of the radiation therapy oncology group.
    International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Drug Evaluation; Glioma; Humans; Misonidazole; Nitroimidazoles; Prognosis

1981
[Clinical experiences with the radiosensitizer Misonidazol (author's transl)].
    Strahlentherapie, 1981, Volume: 157, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Dexamethasone; Drug Interactions; Esophageal Neoplasms; Exanthema; Female; Glioma; Half-Life; Humans; Male; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Phenytoin

1981
Anomalous patterns of nitroimidazole binding adjacent to necrosis in human glioma xenografts: possible role of decreased oxygen consumption.
    British journal of cancer, 1997, Volume: 75, Issue:3

    Topics: Animals; Antineoplastic Agents; Autoradiography; Binding Sites; Cell Line; Glioblastoma; Glioma; Humans; Hypoxia; Mice; Mice, SCID; Misonidazole; Necrosis; Oxygen Consumption; Rats; Rats, Nude; Transplantation, Heterologous; Tritium; Tumor Cells, Cultured

1997
Variable presence of hypoxia in M006 human glioma spheroids and in spheroids and xenografts of clonally derived sublines.
    British journal of cancer, 1998, Volume: 78, Issue:10

    Topics: Animals; Brain Neoplasms; Clone Cells; Deuterium; Glioma; Humans; Hypoxia; Mice; Mice, SCID; Misonidazole; Necrosis; Radiation-Sensitizing Agents; Spheroids, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured

1998
Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:6

    Topics: Animals; Binding Sites; Blood-Brain Barrier; Cell Hypoxia; Chromatography, High Pressure Liquid; Contrast Media; Cricetinae; Cricetulus; Etanidazole; Female; Fibroblasts; Fibrosarcoma; Fluorine Radioisotopes; Glioma; Lung; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Rats; Sarcoma, Experimental; Time Factors; Tissue Distribution; Tumor Cells, Cultured

1999
Determining hypoxic fraction in a rat glioma by uptake of radiolabeled fluoromisonidazole.
    Radiation research, 2000, Volume: 153, Issue:1

    Topics: Administration, Inhalation; Animals; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Radiation; Glioma; Male; Misonidazole; Models, Biological; Oxygen; Oxygen Consumption; Predictive Value of Tests; Radiation-Sensitizing Agents; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tomography, Emission-Computed

2000
Imaging and quantitation of the hypoxic cell fraction of viable tumor in an animal model of intracerebral high grade glioma using [18F]fluoromisonidazole (FMISO).
    Nuclear medicine and biology, 2002, Volume: 29, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Hypoxia; Fluorine Radioisotopes; Glioma; Intestinal Mucosa; Kidney; Liver; Male; Misonidazole; Rats; Rats, Wistar; Tissue Distribution; Tomography, Emission-Computed

2002
Distribution of misonidazole adducts in 9L gliosarcoma tumors and spheroids: implications for oxygen distribution.
    Cancer research, 1992, Jul-15, Volume: 52, Issue:14

    Topics: Animals; Capillaries; Cell Hypoxia; Glioma; Misonidazole; Oxygen; Radiation Tolerance; Rats; Tumor Cells, Cultured

1992
[Radiation therapy of adult cerebral glioblastoma:].
    Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: 35, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Evaluation Studies as Topic; Female; Glioma; Humans; Male; Methods; Middle Aged; Misonidazole; Radiation-Sensitizing Agents; Radiotherapy Dosage; Supratentorial Neoplasms; Survival Rate

1989
Misonidazole and CCNU chemotherapy for recurrent primary brain tumor.
    Journal of neuro-oncology, 1987, Volume: 4, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Glioblastoma; Glioma; Humans; Lomustine; Middle Aged; Misonidazole; Neoplasm Recurrence, Local

1987
Radiation therapy of rat brain tumor using misonidazole as hypoxic cell sensitizer.
    Journal of cancer research and clinical oncology, 1985, Volume: 109, Issue:3

    Topics: Animals; Brain Neoplasms; Dose-Response Relationship, Radiation; Glioma; Misonidazole; Nitroimidazoles; Oxygen; Rats

1985