misonidazole has been researched along with Glioma in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (51.02) | 18.7374 |
| 1990's | 5 (10.20) | 18.2507 |
| 2000's | 4 (8.16) | 29.6817 |
| 2010's | 15 (30.61) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barré, L; Bekaert, L; Bernaudin, M; Bordji, K; Branger, P; Collet, S; Constans, JM; Emery, E; Guillamo, JS; Lechapt-Zalcman, E; Levallet, G; Manrique, A; Petit, E; Ponte, K; Valable, S | 1 |
| Al Jaberi, M; Förster, S; Gempt, J; Göttler, J; Kluge, A; Lukas, M; Meyer, B; Preibisch, C; Pyka, T; Ringel, F; Schlegel, J; Shi, K; Wiestler, B; Zimmer, C | 1 |
| Hirata, K; Houkin, K; Kobayashi, H; Shiga, T; Terasaka, S; Yamaguchi, S | 1 |
| Cao, WD; Haba, R; Kawai, N; Lin, W; Maeda, Y; Miyake, K; Nishiyama, Y; Ogawa, D; Tamiya, T; Yamamoto, Y | 1 |
| Hawkins-Daarud, AJ; Hendrickson, K; Jacobs, J; Kinahan, P; Krohn, KA; Mrugala, MM; Neal, ML; Rockhill, JK; Rockne, RC; Swanson, KR; Trister, AD | 1 |
| Bell, C; Dowson, N; Fay, M; Gal, Y; Puttick, S; Rose, S; Thomas, P | 1 |
| Chen, J; Fan, D; Qian, J; Wang, F; Zhang, Z; Zhu, J | 1 |
| Wang, H; Xu, H; Xue, Y; Yu, W; Zhang, Y; Zhao, X | 1 |
| Hirata, K; Houkin, K; Ishi, Y; Kobayashi, H; Kobayashi, K; Motegi, H; Shiga, T; Tamaki, N; Terasaka, S; Toyonaga, T; Yamaguchi, S | 1 |
| Alessio, AM; Alvord, EC; Anderson, AR; Chakraborty, G; Champley, K; Claridge, J; Gu, S; Kinahan, PE; Krohn, KA; Muzi, M; Rockne, R; Spence, AM; Swanson, KR | 1 |
| Barré, L; Bernaudin, M; Delamare, J; Divoux, D; Marteau, L; Petit, E; Roussel, S; Sobrio, F; Toutain, J; Valable, S | 1 |
| Hattori, N; Hirata, K; Houkin, K; Kobayashi, H; Kuge, Y; Magota, K; Shiga, T; Tamaki, N; Tanaka, S; Terasaka, S; Yamaguchi, S | 1 |
| Aga, F; Kawai, N; Kudomi, N; Maeda, Y; Nishiyama, Y; Ono, Y; Yamamoto, Y | 1 |
| Hanzawa, H; Hatano, T; Kuge, Y; Kuno, N; Nishijima, K; Sakamoto, T; Tamaki, N; Zhao, S; Zhao, Y | 1 |
| Barré, L; Bernaudin, M; Corroyer-Dulmont, A; Divoux, D; Durand, L; MacKenzie, ET; Marteau, L; Pérès, EA; Petit, E; Roussel, S; Toutain, J; Valable, S | 1 |
| Berlangieri, SU; Cher, LM; Fabinyi, G; Hannah, A; Lawrentschuk, N; Murone, C; O'Keefe, GJ; Papenfuss, A; Ramdave, S; Sachinidis, JI; Scott, AM | 1 |
| Lee, ST; Scott, AM | 1 |
| Allen, J; Edwards, MS; Levin, VA; Ortega, J; Vestnys, P; Wara, WM | 1 |
| Fulton, DS; Geggie, PH; Johnson, E; Mielke, B; Moody, J; Muller, PJ; Shin, KH; Tanasichuk, H; Thomas, H; Urtasun, RC | 1 |
| Handa, H; Oda, Y; Ono, K; Otsuka, S; Suda, K; Takeuchi, J; Yamashita, J; Yumitori, K | 1 |
| Strike, TA; Walker, MD | 1 |
| Carabell, S; Goodman, RL; Nelson, DF; Nelson, JS; Schoenfeld, D; Wasserman, T; Weinstein, AS | 1 |
| Onoyama, Y | 1 |
| Davis, DR; Diener, MD; Gillespie, BW; Nelson, DF; Phillips, TL; Stetz, J; Wasserman, T | 1 |
| Gi, H; Handa, H; Oda, Y; Ono, K; Otsuka, S; Suda, K; Takeuchi, J; Yamashita, J | 1 |
| Ang, KK; Chenal, C; Fauchon, F; Goffin, JC; Horiot, JC; Notter, G; Raps, J; van der Schueren, E; van Glabbeke, M; van Peperzeel, H; Vessière, M | 1 |
| Bleehen, NM | 1 |
| Bamberg, M; Scherer, E; Streffer, C; Tamulevicius, P | 2 |
| Phillips, TL; Stetz, J; Wasserman, TH | 1 |
| Barcellos, MH; Bernstein, M; Deen, DF; Gutin, PH; Sano, Y; Shrieve, DC | 1 |
| Otsuka, S | 1 |
| Bruno, LA; Carabell, SC; Chang, CH; Goodman, RL; Richter, MP; Weiler, CB; Weinstein, AS | 1 |
| Allalunis-Turner, MJ; Franko, AJ; Mercer, JR; Mielke, BW; Parliament, MB; Santos, CL; Wolokoff, BG | 1 |
| Allalunis-Turner, MJ; Franko, AJ; Parliament, MB; Wolokoff, BG | 1 |
| Chin, LK; Hofstrand, PD; Rasey, JS; Tewson, TJ | 1 |
| Casciari, JJ; Chin, LK; Graham, MM; Hofstrand, PD; Muzi, M; Rasey, JS | 1 |
| Chan, F; Chan, JG; Cher, L; Hall, C; Hill, J; Kaye, A; Sachinidis, JI; Scott, AM; Stylli, S; Tochon-Danguy, HJ | 1 |
| Bataini, JP; Bernier, J; Brugère, J; Brunin, F; de Narbonne, J; Jaulerry, C | 1 |
| Boisvert, DP; Franko, AJ; Koch, CJ | 1 |
| Burger, PC; Deutsch, M; Green, SB; Mealey, J; Paoletti, P; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Strike, TA | 1 |
| Arai, M; Hayakawa, K; Niibe, H; Tamura, M | 1 |
| Fulton, DS; McKinnon, S; Tanasichuk, H; Urtasun, RC | 1 |
| Gutin, PH; Nelson, DF; Saunders, WM; Sheline, GE; Urtasun, RC | 1 |
| Diener-West, M; Nelson, DF; Pakuris, E; Weinstein, AS | 1 |
| Carabell, S; Chang, CH; Diener-West, M; Goodman, R; Nelson, DF; Nelson, JS; Sause, WT; Schoenfeld, D; Weinstein, AS | 1 |
| Inoue, H; Koizumi, H; Murata, M; Nakamura, M; Niibe, H; Tamura, M; Yonome, I | 1 |
4 review(s) available for misonidazole and Glioma
| Article | Year |
|---|---|
Usefulness of FMISO-PET for glioma analysis.
Topics: Adult; Animals; Brain Neoplasms; Diagnosis, Differential; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Misonidazole; Oxygen; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results | 2013 |
Hypoxia imaging in gliomas with 18F-fluoromisonidazole PET: toward clinical translation.
Topics: Animals; Cell Hypoxia; Glioma; Humans; Misonidazole; Positron-Emission Tomography; Translational Research, Biomedical; Treatment Failure | 2015 |
Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole.
Topics: Animals; Brain Ischemia; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Misonidazole; Myocardial Ischemia; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Stroke | 2007 |
Recent and current investigations of radiation therapy of malignant gliomas.
Topics: Brachytherapy; Brain; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Glioma; Helium; Humans; Hyperbaric Oxygenation; Hyperthermia, Induced; Mesons; Metronidazole; Middle Aged; Misonidazole; Neon; Neutrons; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy, High-Energy | 1986 |
16 trial(s) available for misonidazole and Glioma
| Article | Year |
|---|---|
[18F]-FMISO PET study of hypoxia in gliomas before surgery: correlation with molecular markers of hypoxia and angiogenesis.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Biomarkers, Tumor; Brain Neoplasms; Cerebral Blood Volume; Disease-Free Survival; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Neovascularization, Pathologic; Positron-Emission Tomography; Radiosurgery; Tumor Hypoxia | 2017 |
¹⁸F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas.
Topics: Adult; Aged; Anaplasia; Biological Transport; Brain Neoplasms; Diagnosis, Differential; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Misonidazole; Neoplasm Grading; Positron-Emission Tomography | 2012 |
Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies.
Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Glioma; Glucose; Humans; Male; Metabolic Clearance Rate; Middle Aged; Misonidazole; Neovascularization, Pathologic; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Statistics as Topic | 2006 |
Misonidazole combined with hyperfractionation in the management of malignant glioma.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Glioblastoma; Glioma; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy Dosage; Random Allocation | 1984 |
Misonidazole in radiotherapy of supratentorial malignant brain gliomas in adult patients: a randomized double-blind study.
Topics: Adult; Brain Neoplasms; Clinical Trials as Topic; Double-Blind Method; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Prognosis; Radiotherapy Dosage; Time Factors | 1983 |
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Glioma; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation | 1983 |
[Clinical trials of hypoxic cell sensitizer misonidazole].
Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Evaluation; Female; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Random Allocation; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1983 |
Is misonidazole neurotoxicity altered by the use of phenytoin and/or dexamethasone in RTOG 79-18 and RTOG 79-16?
Topics: Brain Neoplasms; Clinical Trials as Topic; Dexamethasone; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Phenytoin; Radiation-Sensitizing Agents | 1984 |
The Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies.
Topics: Brain Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Glioma; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Phenobarbital; Phenytoin; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1980 |
Misonidazole as a radiosensitizer in the radiotherapy of glioblastomas and oesophageal cancer. Pharmacokinetic and clinical studies.
Topics: Adult; Aged; Brain Neoplasms; Clinical Trials as Topic; Esophageal Neoplasms; Female; Glioma; Humans; Kinetics; Male; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles | 1981 |
Radiation Therapy Oncology Group clinical trials with misonidazole.
Topics: Brain Neoplasms; Clinical Trials as Topic; Drug Administration Schedule; Glioma; Head and Neck Neoplasms; Humans; Misonidazole; Nausea; Nervous System Diseases; Nitroimidazoles; Radiotherapy Dosage; Random Allocation; Vomiting | 1981 |
[Clinical testing of the radiosensitizer RO-07-0582 (misonidazole). Dose tolerance, toxicity and pharmacokinetic studies, preliminary report (author's transl)].
Topics: Bone Neoplasms; Clinical Trials as Topic; Glioma; Humans; Kinetics; Misonidazole; Neoplasms; Nitroimidazoles; Otorhinolaryngologic Diseases; Sarcoma | 1978 |
Prognostic factors for high-grade malignant glioma: development of a prognostic index. A Report of the Medical Research Council Brain Tumour Working Party.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Multivariate Analysis; Prognosis; Proportional Hazards Models | 1990 |
Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma.
Topics: Adolescent; Adult; Aged; Astrocytoma; Carmustine; Combined Modality Therapy; Glioblastoma; Glioma; Humans; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prognosis; Radiotherapy Dosage; Random Allocation; Streptozocin; Supratentorial Neoplasms | 1989 |
Pulmonary toxicity of carmustine in patients treated for malignant glioma.
Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Glioma; Humans; Lung Diseases; Male; Middle Aged; Misonidazole; Random Allocation; Risk | 1986 |
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study.
Topics: Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Glioma; Humans; Middle Aged; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation | 1986 |
29 other study(ies) available for misonidazole and Glioma
| Article | Year |
|---|---|
Characterizing hypoxia in human glioma: A simultaneous multimodal MRI and PET study.
Topics: Aged; Brain Neoplasms; Cell Hypoxia; Female; Glioma; Humans; Image Enhancement; Immunohistochemistry; Magnetic Resonance Imaging; Male; Middle Aged; Misonidazole; Positron-Emission Tomography | 2017 |
Correlation between ¹⁸F-fluoromisonidazole PET and expression of HIF-1α and VEGF in newly diagnosed and recurrent malignant gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; Female; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Vascular Endothelial Growth Factor A | 2014 |
A patient-specific computational model of hypoxia-modulated radiation resistance in glioblastoma using 18F-FMISO-PET.
Topics: Aged; Brain Neoplasms; Glioma; Humans; Hypoxia; Male; Misonidazole; Models, Biological; Positron-Emission Tomography; Precision Medicine; Radiation-Sensitizing Agents; Radiography | 2015 |
Preparation and Biodistribution of Technetium-99m-Labeled Bis- Misonidazole (MISO) as an Imaging Agent for Tumour Hypoxia.
Topics: Animals; Autoradiography; Cell Hypoxia; Glioma; Male; Mice; Mice, Inbred ICR; Misonidazole; Oils; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Water | 2015 |
Radiosensitizing effect of irisquinone on glioma through the downregulation of HIF-1α evaluated by 18F-FDG and 18F-FMISO PET/CT.
Topics: Animals; Benzoquinones; Cell Line, Tumor; Down-Regulation; Fluorodeoxyglucose F18; Glioma; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Misonidazole; Positron Emission Tomography Computed Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tumor Hypoxia | 2016 |
Change in 18F-Fluoromisonidazole PET Is an Early Predictor of the Prognosis in the Patients with Recurrent High-Grade Glioma Receiving Bevacizumab Treatment.
Topics: Adult; Aged; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Glioma; Humans; Magnetic Resonance Imaging; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Retrospective Studies | 2016 |
Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images.
Topics: Adult; Brain Neoplasms; Cell Proliferation; Computer Simulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Mathematical Concepts; Misonidazole; Models, Biological; Necrosis; Neoplasm Invasiveness; Neovascularization, Pathologic; Positron-Emission Tomography; Precision Medicine; Radiopharmaceuticals; User-Computer Interface | 2012 |
Complementary information from magnetic resonance imaging and (18)F-fluoromisonidazole positron emission tomography in the assessment of the response to an antiangiogenic treatment in a rat brain tumor model.
Topics: Angiogenesis Inhibitors; Animals; Biological Transport; Brain; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cerebrovascular Circulation; Disease Models, Animal; Glioma; Indoles; Kinetics; Magnetic Resonance Imaging; Misonidazole; Neovascularization, Pathologic; Permeability; Positron-Emission Tomography; Pyrroles; Rats; Sunitinib; Treatment Outcome | 2011 |
Hypoxia assessed by 18F-fluoromisonidazole positron emission tomography in newly diagnosed gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Hypoxia; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiation-Sensitizing Agents; Retrospective Studies; Young Adult | 2012 |
Biological characteristics of intratumoral [F-18]‑fluoromisonidazole distribution in a rodent model of glioma.
Topics: Animals; Autoradiography; Biological Transport; Brain Neoplasms; Cell Hypoxia; Cell Proliferation; Fluorodeoxyglucose F18; Glioma; Glucose; Glucose Transporter Type 1; Hexokinase; Hypoxia-Inducible Factor 1; Ki-67 Antigen; Male; Misonidazole; Nitroimidazoles; Rats; Rats, Wistar; Tissue Distribution | 2013 |
Noninvasive assessment of hypoxia with 3-[18F]-fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([18F]-FMISO): a PET study in two experimental models of human glioma.
Topics: Glioma; Humans; Hypoxia; Immunohistochemistry; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Misonidazole; Positron-Emission Tomography | 2013 |
5-Fluorouracil and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) followed by hydroxyurea, misonidazole, and irradiation for brain stem gliomas: a pilot study of the Brain Tumor Research Center and the Childrens Cancer Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Lomustine; Male; Misonidazole; Prognosis; Radioisotope Teletherapy | 1984 |
[Radiosensitizing effect of misonidazole on intracranially transplanted tumors in mice and its clinical application (author's transl)].
Topics: Adult; Aged; Animals; Brain Neoplasms; Cobalt Radioisotopes; Female; Glioma; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1982 |
Misonidazole peripheral neuropathy: its relationship to plasma concentration and other drugs.
Topics: Adrenal Cortex Hormones; Barbiturates; Brain Neoplasms; Drug Interactions; Female; Glioma; Half-Life; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Phenytoin | 1980 |
[Local administration of radiosensitizer misonidazole].
Topics: Adult; Aged; Animals; Astrocytoma; Brain Neoplasms; Dogs; Drug Implants; Female; Glioma; Humans; Injections, Spinal; Kinetics; Male; Mice; Mice, Inbred C57BL; Misonidazole; Nitroimidazoles; Rats; Silicone Elastomers; Uterine Neoplasms | 1983 |
Split course multiple daily fractionated radiotherapy schedule combined with misonidazole for the management of grade III and IV gliomas. A pilot feasibility study of the Radiotherapy Group of the EORTC.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Female; Glioma; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prognosis; Radiotherapy Dosage; Radiotherapy, High-Energy | 1982 |
Further evidence for the absence of a hypoxic fraction in the 9L rat tumour multicellular spheroid system.
Topics: Animals; Cell Survival; Glioma; Misonidazole; Neoplasms, Experimental; Oxygen; Rats | 1982 |
[Radiosensitizing effect of misonidazole in radiotherapy for intracranial tumors].
Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Child; Drug Implants; Female; Glioma; Humans; Male; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Silicone Elastomers | 1982 |
Misonidazole and radiotherapy to treat malignant glioma: a phase II trial of the radiation therapy oncology group.
Topics: Astrocytoma; Brain Neoplasms; Drug Evaluation; Glioma; Humans; Misonidazole; Nitroimidazoles; Prognosis | 1981 |
[Clinical experiences with the radiosensitizer Misonidazol (author's transl)].
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Dexamethasone; Drug Interactions; Esophageal Neoplasms; Exanthema; Female; Glioma; Half-Life; Humans; Male; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Phenytoin | 1981 |
Anomalous patterns of nitroimidazole binding adjacent to necrosis in human glioma xenografts: possible role of decreased oxygen consumption.
Topics: Animals; Antineoplastic Agents; Autoradiography; Binding Sites; Cell Line; Glioblastoma; Glioma; Humans; Hypoxia; Mice; Mice, SCID; Misonidazole; Necrosis; Oxygen Consumption; Rats; Rats, Nude; Transplantation, Heterologous; Tritium; Tumor Cells, Cultured | 1997 |
Variable presence of hypoxia in M006 human glioma spheroids and in spheroids and xenografts of clonally derived sublines.
Topics: Animals; Brain Neoplasms; Clone Cells; Deuterium; Glioma; Humans; Hypoxia; Mice; Mice, SCID; Misonidazole; Necrosis; Radiation-Sensitizing Agents; Spheroids, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia.
Topics: Animals; Binding Sites; Blood-Brain Barrier; Cell Hypoxia; Chromatography, High Pressure Liquid; Contrast Media; Cricetinae; Cricetulus; Etanidazole; Female; Fibroblasts; Fibrosarcoma; Fluorine Radioisotopes; Glioma; Lung; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Rats; Sarcoma, Experimental; Time Factors; Tissue Distribution; Tumor Cells, Cultured | 1999 |
Determining hypoxic fraction in a rat glioma by uptake of radiolabeled fluoromisonidazole.
Topics: Administration, Inhalation; Animals; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Radiation; Glioma; Male; Misonidazole; Models, Biological; Oxygen; Oxygen Consumption; Predictive Value of Tests; Radiation-Sensitizing Agents; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tomography, Emission-Computed | 2000 |
Imaging and quantitation of the hypoxic cell fraction of viable tumor in an animal model of intracerebral high grade glioma using [18F]fluoromisonidazole (FMISO).
Topics: Animals; Brain Neoplasms; Cell Hypoxia; Fluorine Radioisotopes; Glioma; Intestinal Mucosa; Kidney; Liver; Male; Misonidazole; Rats; Rats, Wistar; Tissue Distribution; Tomography, Emission-Computed | 2002 |
Distribution of misonidazole adducts in 9L gliosarcoma tumors and spheroids: implications for oxygen distribution.
Topics: Animals; Capillaries; Cell Hypoxia; Glioma; Misonidazole; Oxygen; Radiation Tolerance; Rats; Tumor Cells, Cultured | 1992 |
[Radiation therapy of adult cerebral glioblastoma:].
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Evaluation Studies as Topic; Female; Glioma; Humans; Male; Methods; Middle Aged; Misonidazole; Radiation-Sensitizing Agents; Radiotherapy Dosage; Supratentorial Neoplasms; Survival Rate | 1989 |
Misonidazole and CCNU chemotherapy for recurrent primary brain tumor.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Glioblastoma; Glioma; Humans; Lomustine; Middle Aged; Misonidazole; Neoplasm Recurrence, Local | 1987 |
Radiation therapy of rat brain tumor using misonidazole as hypoxic cell sensitizer.
Topics: Animals; Brain Neoplasms; Dose-Response Relationship, Radiation; Glioma; Misonidazole; Nitroimidazoles; Oxygen; Rats | 1985 |