Page last updated: 2024-08-22

misonidazole and EHS Tumor

misonidazole has been researched along with EHS Tumor in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	64 (85.33)	18.7374
1990's	11 (14.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adams, GE; Cole, S; Fielden, EM; Naylor, MA; O'Neill, P; Stephens, MA; Stratford, IJ; Threadgill, MD; Webb, P	1
Mulcahy, RT; Siemann, DW; Sutherland, RM	2
Twentyman, PR	1
McNally, NJ	1
Denekamp, J; Rojas, A; Stewart, FA	1
Denekamp, J; Rojas, A	1
Brown, DM; Brown, JM; Lee, WW; Yu, NY	1
Siemann, DW	4
Brown, JM; Evans, JW; Horsman, MR	1
Hill, SA; Keng, PC; Siemann, DW	1
Bauer, KD; Hill, SA; Keng, PC; Siemann, DW	1
Hill, SA; Siemann, DW	2
Maddison, K; Siemann, DW; Wolf, K	1
Grdina, DJ; Milas, L; Thames, HD	1
Lee, FY; Workman, P	2
Alvarez, R; Burgos, S; Correa, JN; Figueroa, A; Guzman, P; Infante, GA; Lanier, LJ; Myers, JA; Vera, J; Williams, TM	1
Meyn, RE; Murray, D	1
Morrissey, S; Siemann, DW; Wolf, K	1
Baer, K; Chapman, JD; Lee, J	1
Twentyman, PR; Workman, P	1
de Ronde, J; Hinchliffe, M; McNally, NJ	1
Mulcahy, RT; Siemann, DW	1
Brown, JM; Twentyman, PR; Zamvil, SS	1
Goldfeder, A	1
Crabtree, KE; Curtis, SB; Flynn, MJ; Howard, J; Lyman, JT; Parr, SS; Tenforde, SD; Tenforde, TS	1
Twentyman, P; Workman, P	1
Brown, JM; Hirst, DG	1
Denekamp, J; Hill, SA	1
Reinhold, HS; van den Berg-Blok, A	1
Chin, JB; Rauth, AM	1
Kochanski, K; Siemann, DW	1
Chapman, JD; Franko, AJ; Sharplin, J	1
De Ronde, J; Martin, WM; McNally, NJ	1
Brown, JM; Hirst, DG; Law, MP	1
Grimmett, EV; Hofer, KG; Lehr, JE; MacKinnon, AR; Schubert, AL	1
Denekamp, J; Hirst, DG; Stewart, FA; Terry, NH	1
Grdina, DJ; Jovonovich, JA; Sigdestad, CP	1
Tannock, IF	2
Adams, GE; Bradley, JK; Bremner, JC; Naylor, MA; Sansom, JM; Stratford, IJ	1
Chin, LK; Hofstrand, PD; Rasey, JS; Tewson, TJ	1
Deys, BF; Stap, J	1
Brown, JM	1
Siemann, DW; Sutherland, RM	1
Adams, GE; Cole, S; Elliott, W; Fielden, EM; Leopold, W; Sebolt-Leopold, J; Stratford, IJ; Suto, M	1
Binger, M; Workman, P	1
Adams, GE; Bowler, J; Cole, S; Lorimore, SA; Nolan, J; Stratford, IJ; Wright, EG	1
Hunter, N; Ito, H; Milas, L; Nakayama, T	1
Adams, GE; Bowler, J; Bremner, JC; Stratford, IJ	1
Adams, GE; Cole, S; Fielden, EM; Jenkins, TC; Stratford, IJ	1
Herman, TS; Holden, SA; Jones, SM; Teicher, BA	1
Deacon, J; Holliday, S; Stratford, IJ; Walling, JM	1
Herman, TS; Kaufmann, M; Teicher, BA	1
Gulyas, S; Hill, RP; Whitmore, GF	1
Griffiths, JR; Maxwell, RJ; Workman, P	1
Grierson, JR; Grunbaum, Z; Koh, WJ; Krohn, KA; Rasey, JS	1
Hunter, N; Milas, L; Peters, LJ	1
Hofer, KG; Hofer, MG; Lakkis, M	1
Adams, GE; Godden, J; Howells, N; Nolan, J; Stratford, IJ; Timpson, N	1
Murray, JC; Randhawa, VS	1
Allalunis-Turner, MJ; Siemann, DW	1
Gipp, JJ; Mulcahy, RT; Tanner, MA	1
Denekamp, J; Murray, JC; Randhawa, V	1
Dynlacht, J; Friedland, JL; Hofer, KG; Hofer, MG	1
Durand, RE; Grunbaum, Z; Krohn, KA; Magee, S; Nelson, NJ; Olive, PL; Rasey, JS	1
Chaplin, DJ; Durand, RE	1
Workman, P	1
Alliet, KL; Siemann, DW	1
Hill, SA; Keng, PC; Maddison, K; Siemann, DW; Wolf, K	1

Other Studies

75 other study(ies) available for misonidazole and EHS Tumor

Article	Year
Synthesis of a series of nitrothiophenes with basic or electrophilic substituents and evaluation as radiosensitizers and as bioreductively activated cytotoxins. Journal of medicinal chemistry, 1991, Volume: 34, Issue:7 Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Mice; Nitro Compounds; Radiation-Sensitizing Agents; Sarcoma, Experimental; Structure-Activity Relationship; Thiophenes	1991
Nitrosourea-misonidazole combination chemotherapy: effect on KHT sarcomas, marrow stem cells and gut. British journal of cancer, 1982, Volume: 45, Issue:6 Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Streptozocin	1982
Modification of tumour and host response to cyclophosphamide by misonidazole and by WR 2721. British journal of cancer, 1981, Volume: 43, Issue:6 Topics: Amifostine; Animals; Body Weight; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Leukocyte Count; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Organothiophosphorus Compounds; Sarcoma, Experimental	1981
The effect of misonidazole combined with WR2721 on tumour response and leucopenia due to cyclophosphamide or melphalan. British journal of cancer, 1982, Volume: 46, Issue:4 Topics: Amifostine; Animals; Cell Survival; Cyclophosphamide; Drug Therapy, Combination; Leukopenia; Melphalan; Mice; Mice, Inbred Strains; Misonidazole; Nitroimidazoles; Organothiophosphorus Compounds; Sarcoma, Experimental	1982
Interaction of misonidazole and WR-2721--II. Modification of tumour radiosensitization. British journal of cancer, 1983, Volume: 47, Issue:1 Topics: Amifostine; Animals; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Fibrosarcoma; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Organothiophosphorus Compounds; Radiation Tolerance; Sarcoma, Experimental	1983
Time dependence of interaction of misonidazole and WR-2721. The British journal of radiology, 1983, Volume: 56, Issue:668 Topics: Amifostine; Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Fibrosarcoma; Mice; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Organothiophosphorus Compounds; Sarcoma, Experimental; Time Factors	1983
SR-2508: a 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use. International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:6 Topics: Animals; Carcinoma; Cell Line; Central Nervous System; Cricetinae; Dogs; Etanidazole; Female; In Vitro Techniques; Lipid Metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; X-Rays	1981
Response of murine tumours to combinations of CCNU with misonidazole and other radiation sensitizers. British journal of cancer, 1982, Volume: 45, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanidazole; Female; Leukocyte Count; Lomustine; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Sarcoma, Experimental	1982
Enhancement of melphalan-induced tumour cell killing by misonidazole: an interaction of competing mechanisms. British journal of cancer, 1984, Volume: 50, Issue:3 Topics: Animals; Body Temperature; Cell Survival; Drug Synergism; Female; Kinetics; Melphalan; Metabolic Clearance Rate; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Sarcoma, Experimental; Time Factors	1984
Survival in subpopulations of cells derived from solid KHT sarcomas by centrifugal elutriation following treatment with CCNU and MISO. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Cell Cycle; Cell Separation; Cell Survival; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental	1984
The effect in the KHT sarcoma of CCNU and MISO on cell cycle progression evaluated by flow-cytometry. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Cell Cycle; DNA, Neoplasm; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; RNA, Neoplasm; Sarcoma, Experimental	1984
Enhanced tumor responses through therapies combining CCNU, MISO and radiation. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Combined Modality Therapy; Drug Synergism; Drug Therapy, Combination; Female; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; Time Factors	1984
Chemopotentiation in vivo: no loss of sensitization with fractionation. British journal of cancer, 1984, Volume: 50, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Leukocyte Count; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Sarcoma, Experimental	1984
Potentiation of melphalan activity in the KHT sarcoma by the radiosensitizer RSU 1069. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Aziridines; Azirines; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Melphalan; Mice; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; Time Factors	1984
Tumor sensitizing effect by misonidazole in a clinically relevant radiation dose range. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:3 Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Radiation; Female; Fibrosarcoma; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation Tolerance; Sarcoma, Experimental; Tumor Stem Cell Assay	1984
Misonidazole and CCNU: further evidence for a pharmacokinetic mechanism of chemosensitization and therapeutic gain. British journal of cancer, 1984, Volume: 49, Issue:5 Topics: Animals; Bone Marrow; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Intestine, Small; Kinetics; Lomustine; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1984
Radiosensitization by derivatives of isoindole-4,7-dione. Radiation research, 1984, Volume: 98, Issue:2 Topics: Animals; Chemical Phenomena; Chemistry; Indoles; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasm Transplantation; Pulse Radiolysis; Radiation-Sensitizing Agents; Sarcoma, Experimental	1984
Enhancement of the DNA cross-linking activity of melphalan by misonidazole in vivo. British journal of cancer, 1983, Volume: 47, Issue:2 Topics: Animals; Cross-Linking Reagents; DNA; DNA Repair; DNA, Neoplasm; Fibrosarcoma; Glutathione; Jejunum; Maleates; Melphalan; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Spleen	1983
In vivo potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea by the radiation sensitizer benznidazole. Cancer research, 1983, Volume: 43, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Sarcoma, Experimental; Time Factors	1983
Characteristics of the metabolism-induced binding of misonidazole to hypoxic mammalian cells. Cancer research, 1983, Volume: 43, Issue:4 Topics: Anaerobiosis; Animals; Binding, Competitive; Cell Line; Cricetinae; Cricetulus; Fibrosarcoma; Kidney; Kinetics; Mice; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Temperature	1983
Chemosensitization by lipophilic nitroimidazoles. British journal of cancer, 1983, Volume: 48, Issue:1 Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Leukocyte Count; Lomustine; Male; Melphalan; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Time Factors	1983
Enhancement of the action of alkylating agents by single high, or chronic low doses of misonidazole. British journal of cancer, 1983, Volume: 48, Issue:2 Topics: Animals; Cell Survival; Cyclophosphamide; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Leukopenia; Melphalan; Mice; Mice, Inbred Strains; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Time Factors	1983
In vivo chemosensitization by misonidazole in sensitive and resistant tumor lines. Cancer research, 1983, Volume: 43, Issue:10 Topics: Animals; Carmustine; Cell Line; Drug Resistance; Drug Synergism; Humans; Leukemia L1210; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Sarcoma, Experimental	1983
Response to the RIF-1 tumor in vitro and in C3H/Km mice to X-radiation (cell survival, regrowth delay, and tumor control), chemotherapeutic agents, and activated macrophages. Journal of the National Cancer Institute, 1980, Volume: 64, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cytotoxicity, Immunologic; Female; Immunotherapy; Macrophages; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Radiation-Induced; Sarcoma, Experimental	1980
Cell kinetics, cell structure, and radiotherapy. Annals of the New York Academy of Sciences, 1982, Dec-10, Volume: 397 Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Computers; Female; Hot Temperature; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Microscopy, Electron; Misonidazole; Sarcoma, Experimental	1982
Misonidazole enhancement of radiation-induced growth delay in rat rhabdomyosarcoma tumours exposed to accelerated carbon and neon ions. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1981, Volume: 40, Issue:2 Topics: Animals; Carbon; Cell Survival; Dose-Response Relationship, Radiation; Energy Transfer; Misonidazole; Neon; Nitroimidazoles; Particle Accelerators; Radiation-Sensitizing Agents; Rats; Rhabdomyosarcoma; Sarcoma, Experimental	1981
Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU. British journal of cancer, 1982, Volume: 45, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Survival; Chlorambucil; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Lethal Dose 50; Leukocyte Count; Lomustine; Male; Melphalan; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1982
Effect of clinical levels of misonidazole on the response of tumour and normal tissues in the mouse to alkylating agents. British journal of cancer, 1982, Volume: 45, Issue:5 Topics: Animals; Bone Marrow; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Female; Lethal Dose 50; Leukocyte Count; Melphalan; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1982
Site dependent response of tumours to combined heat and radiation. The British journal of radiology, 1982, Volume: 55, Issue:660 Topics: Animals; Dose-Response Relationship, Radiation; Foot; Hindlimb; Hot Temperature; Mice; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Regional Blood Flow; Sarcoma, Experimental; Soft Tissue Neoplasms; Tail; Temperature; Thorax	1982
Enhancement of thermal damage to the microcirculation of 'sandwich' tumours by additional treatment. European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7 Topics: Animals; Glucose; Hot Temperature; Microcirculation; Misonidazole; Radiation-Sensitizing Agents; Rats; Rats, Inbred Strains; Rhabdomyosarcoma; Sarcoma, Experimental; Time Factors	1981
In vivo combination of misonidazole and the chemotherapeutic agent CCNU. British journal of cancer, 1981, Volume: 43, Issue:3 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Lomustine; Mice; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Sarcoma, Experimental; Time Factors	1981
The metabolism and pharmacokinetics of the hypoxic cell radiosensitizer and cytotoxic agent, misonidazole, in C3H mice. Radiation research, 1981, Volume: 86, Issue:2 Topics: Animals; Autoradiography; Chromatography, Paper; Kinetics; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Oxygen; Polarography; Sarcoma, Experimental; Time Factors; Tissue Distribution	1981
Combinations of radiation and misonidazole in a murine lung tumor model. Radiation research, 1981, Volume: 86, Issue:2 Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Female; Lung; Lung Neoplasms; Mice; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radiotherapy; Sarcoma, Experimental; Time Factors	1981
A marker for hypoxic cells in tumours with potential clinical applicability. British journal of cancer, 1981, Volume: 43, Issue:4 Topics: Animals; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Cricetinae; Fibrosarcoma; Mice; Mice, Inbred BALB C; Misonidazole; Oxygen Consumption; Sarcoma, Experimental	1981
Enhancement of the effect of cytotoxic drugs by radiosensitizers. British journal of cancer, 1981, Volume: 43, Issue:6 Topics: Animals; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Fibrosarcoma; In Vitro Techniques; Melphalan; Mice; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; Urination	1981
Enhancing effect of misonidazole on the response of the RIF-1 tumour to cyclophosphamide. British journal of cancer, 1981, Volume: 44, Issue:2 Topics: Animals; Cell Line; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Hematopoietic Stem Cells; Leukocytes; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1981
Radiosensitization of tumors and normal tissues by combined treatment with misonidazole and heat. Radiology, 1981, Volume: 141, Issue:3 Topics: Animals; Bone Marrow; Cell Survival; Cells, Cultured; Dose-Response Relationship, Radiation; Female; Hot Temperature; Intestinal Mucosa; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Oxygen; Radiation Tolerance; Sarcoma, Experimental; Skin	1981
Is tumour radiosensitization by misonidazole a general phenomenon? British journal of cancer, 1980, Volume: 41, Issue:1 Topics: Animals; Carcinoma; Cell Line; Dose-Response Relationship, Radiation; Male; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance; Sarcoma, Experimental; Time Factors	1980
The effect of misonidazole in situ on the radiation response of selected tumor subpopoulations. Cancer clinical trials, 1980,Summer, Volume: 3, Issue:2 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Fibrosarcoma; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental	1980
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: methotrexate, 5-fluorouracil and adriamycin. British journal of cancer, 1980, Volume: 42, Issue:6 Topics: Animals; Body Weight; Doxorubicin; Drug Therapy, Combination; Fibrosarcoma; Fluorouracil; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Methotrexate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1980
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: cyclophosphamide and BCNU. British journal of cancer, 1980, Volume: 42, Issue:6 Topics: Animals; Body Weight; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Fibrosarcoma; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1980
In vivo response of KHT sarcomas to combination chemotherapy with radiosensitizers and BCNU. British journal of cancer, 1981, Volume: 43, Issue:1 Topics: Animals; Carmustine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Time Factors	1981
Comparing the anti-tumor effect of several bioreductive drugs when used in combination with photodynamic therapy (PDT). International journal of radiation oncology, biology, physics, 1994, May-15, Volume: 29, Issue:2 Topics: Animals; Antineoplastic Agents; Mice; Mice, Inbred C3H; Misonidazole; Mitomycin; Nitroimidazoles; Photochemotherapy; Sarcoma, Experimental	1994
Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:6 Topics: Animals; Binding Sites; Blood-Brain Barrier; Cell Hypoxia; Chromatography, High Pressure Liquid; Contrast Media; Cricetinae; Cricetulus; Etanidazole; Female; Fibroblasts; Fibrosarcoma; Fluorine Radioisotopes; Glioma; Lung; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Rats; Sarcoma, Experimental; Time Factors; Tissue Distribution; Tumor Cells, Cultured	1999
Influence of the hypoxic cell sensitizer misonidazole on the proliferation of well-oxygenated cells in vitro during prolonged exposure. British journal of cancer, 1979, Volume: 40, Issue:5 Topics: Animals; Cell Cycle; Cell Division; Cell Line; Hypoxia; Mice; Misonidazole; Mitosis; Nitroimidazoles; Osteosarcoma; Oxygen; Sarcoma, Experimental; Time Factors	1979
Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation. The British journal of radiology, 1979, Volume: 52, Issue:620 Topics: Animals; Cell Survival; Mice; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen; Radiation Tolerance; Sarcoma, Experimental; Transplantation, Homologous	1979
Potentiation of alkylating chemotherapy by dual function nitrofurans in multi-cell spheroids and solid tumors. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1992, Volume: 24, Issue:4 Topics: Animals; Antineoplastic Agents; Aziridines; Bone Marrow; Carcinoma; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Lomustine; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Misonidazole; Nitrofurans; Radiation-Sensitizing Agents; Sarcoma, Experimental; Stem Cells; Tumor Cells, Cultured	1992
Dual function nitroimidazoles less toxic than RSU 1069: selection of candidate drugs for clinical trial (RB 6145 and/or PD 130908. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Animals; Cell Hypoxia; Combined Modality Therapy; Drug Evaluation; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental	1992
Pharmacokinetic contribution to the improved therapeutic selectivity of a novel bromoethylamino prodrug (RB 6145) of the mixed-function hypoxic cell sensitizer/cytotoxin alpha-(1-aziridinomethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069). Cancer chemotherapy and pharmacology, 1991, Volume: 29, Issue:1 Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Female; Half-Life; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Prodrugs; Sarcoma, Experimental	1991
Oral (po) dosing with RSU 1069 or RB 6145 maintains their potency as hypoxic cell radiosensitizers and cytotoxins but reduces systemic toxicity compared with parenteral (ip) administration in mice. International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:2 Topics: Administration, Oral; Animals; Combined Modality Therapy; Injections, Intraperitoneal; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental	1991
Improvement in therapeutic ratio of radiotherapy for a murine sarcoma by indomethacin plus misonidazole. Cancer research, 1991, Jul-15, Volume: 51, Issue:14 Topics: Animals; Drug Therapy, Combination; Female; Indomethacin; Mice; Mice, Inbred C3H; Misonidazole; Radiation Tolerance; Sarcoma, Experimental	1991
Bioreductive drugs and the selective induction of tumour hypoxia. British journal of cancer, 1990, Volume: 61, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Constriction; Hydralazine; Mice; Mice, Inbred C3H; Misonidazole; Mitomycin; Mitomycins; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tirapazamine; Triazines	1990
Enhancement of chemotherapy and nitroimidazole-induced chemopotentiation by the vasoactive agent hydralazine. British journal of cancer, 1990, Volume: 62, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cyclophosphamide; Drug Synergism; Female; Hydralazine; Lomustine; Melphalan; Mice; Mice, Inbred C3H; Misonidazole; Sarcoma, Experimental; Stem Cells	1990
Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas. Radiation research, 1990, Volume: 124, Issue:1 Suppl Topics: Animals; Antineoplastic Agents; Female; Mice; Mice, Inbred C3H; Misonidazole; Prodrugs; Radiation-Sensitizing Agents; Sarcoma, Experimental	1990
Addition of misonidazole, etanidazole, or hyperthermia to treatment with fluosol-DA/carbogen/radiation. Journal of the National Cancer Institute, 1989, Jun-21, Volume: 81, Issue:12 Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Drug Combinations; Etanidazole; Fibrosarcoma; Fluorocarbons; Hydroxyethyl Starch Derivatives; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental	1989
High uptake of RSU 1069 and its analogues melanotic melanomas. Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:1 Topics: Animals; Cell Line; Cell Membrane Permeability; Deoxyribonucleases; Drug Evaluation, Preclinical; Half-Life; Humans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Microbial Collagenase; Misonidazole; Sarcoma, Experimental; Tissue Distribution; Trypsin; Tumor Cells, Cultured	1989
Platinum complexes of triaminotriphenylmethanes: interaction with DNA and radiosensitization. Cancer letters, 1989, Volume: 47, Issue:3 Topics: Animals; Cell Hypoxia; Cell Survival; DNA; Dose-Response Relationship, Drug; Fibrosarcoma; Male; Methyl Green; Mice; Mice, Inbred C3H; Misonidazole; Molecular Conformation; Neoplasm Transplantation; Organoplatinum Compounds; Radiation-Sensitizing Agents; Rosaniline Dyes; Sarcoma, Experimental; Tumor Cells, Cultured	1989
Toxicity of RSU-1069 for KHT cells treated in vivo or in vitro: evidence for a diffusible toxic product. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Cell Count; Cell Survival; Diffusion; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tumor Cells, Cultured	1989
The chemosensitizing and cytotoxic effects of RSU 1164 and RSU 1165 in a murine tumor model. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Synergism; Lomustine; Mice; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tumor Cells, Cultured; Tumor Stem Cell Assay	1989
Demonstration of tumor-selective retention of fluorinated nitroimidazole probes by 19F magnetic resonance spectroscopy in vivo. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental	1989
Radiolabelled fluoromisonidazole as an imaging agent for tumor hypoxia. International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:5 Topics: Adenocarcinoma; Animals; Bone Neoplasms; Cell Hypoxia; Cells, Cultured; Contrast Media; Cricetinae; Cricetulus; Dogs; Fibroblasts; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Osteosarcoma; Radiation Tolerance; Radionuclide Imaging; Sarcoma, Experimental	1989
Tumor bed effect-induced reduction of tumor radiocurability through the increase in hypoxic cell fraction. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:1 Topics: Aerobiosis; Anaerobiosis; Animals; Extremities; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen; Radiation Tolerance; Sarcoma, Experimental	1989
Cytocidal effects of misonidazole, Ro 03-8799, and RSU-1164 on euoxic and hypoxic BP-8 murine sarcoma cells at normal and elevated temperatures. Cancer, 1989, Apr-15, Volume: 63, Issue:8 Topics: Animals; Combined Modality Therapy; Female; Hyperthermia, Induced; Iodine Radioisotopes; Mice; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tumor Cells, Cultured	1989
Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine. British journal of cancer, 1988, Volume: 58, Issue:2 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Hydralazine; Male; Melphalan; Mice; Mice, Inbred C3H; Misonidazole; Oxygen Consumption; Sarcoma, Experimental; Time Factors	1988
Misonidazole reduces blood flow in two experimental murine tumours. British journal of cancer, 1988, Volume: 58, Issue:2 Topics: Animals; Blood Volume; Carcinoma; Depression, Chemical; Kidney; Mice; Mice, Inbred Strains; Misonidazole; Muscles; Regional Blood Flow; Sarcoma, Experimental; Skin; Time Factors	1988
Potentiation of combination chemotherapy by nitroheterocyclics. International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Synergism; Female; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Radiation-Sensitizing Agents; Sarcoma, Experimental	1988
Enhancement of misonidazole chemopotentiation by mild hyperthermia (41 degrees C) in vitro and selective enhancement in vivo. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1987, Volume: 52, Issue:1 Topics: Aerobiosis; Animals; Cell Line; Combined Modality Therapy; Drug Synergism; Female; Hot Temperature; Hyperthermia, Induced; Lomustine; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Oxygen; Sarcoma, Experimental	1987
The effects of melphalan and misonidazole on the vasculature of a murine sarcoma. British journal of cancer, 1987, Volume: 55, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Basement Membrane; Benzimidazoles; Blood Vessels; Fluorescent Antibody Technique; Fluorescent Dyes; Melphalan; Mice; Mice, Inbred Strains; Misonidazole; Sarcoma, Experimental	1987
Radiosensitizing and cytocidal effects of misonidazole: evidence for separate modes of action. Radiation research, 1987, Volume: 111, Issue:1 Topics: Animals; Cell Cycle; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Idoxuridine; Mathematics; Mice; Misonidazole; Radiation Tolerance; Sarcoma, Experimental	1987
Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells. Radiation research, 1987, Volume: 111, Issue:2 Topics: Animals; Autoradiography; Biotransformation; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hypoxia; Mice; Mice, Inbred C3H; Misonidazole; Oxygen; Radionuclide Imaging; Sarcoma, Experimental; Tritium	1987
Chemosensitization by misonidazole in CCNU-treated spheroids and tumours. British journal of cancer, 1987, Volume: 56, Issue:2 Topics: Animals; Cell Line; Cell Separation; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Lomustine; Misonidazole; Sarcoma, Experimental	1987
Altered pharmacokinetics in the mechanism of chemosensitization: effects of nitroimidazoles and other chemical modifiers on the pharmacokinetics, antitumour activity and acute toxicity of selected nitrogen mustards. Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:1 Topics: Animals; Blood Proteins; Chromatography, High Pressure Liquid; Drug Interactions; Hydrolysis; Kinetics; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitrogen Mustard Compounds; Nitroimidazoles; Protein Binding; Sarcoma, Experimental	1986
Chemosensitization of lomustine by misonidazole, benznidazole, and RSU 1069. Cancer treatment reports, 1986, Volume: 70, Issue:9 Topics: Animals; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1986
Combinations of CCNU, MISO, and fractionated radiotherapy. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:8 Topics: Animals; Combined Modality Therapy; Lomustine; Mice; Misonidazole; Radiation-Sensitizing Agents; Radiotherapy Dosage; Sarcoma, Experimental	1986
In vivo interaction between radiation and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in the absence or presence of misonidazole in mice. Cancer research, 1985, Volume: 45, Issue:1 Topics: Animals; Combined Modality Therapy; Female; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental; Tumor Stem Cell Assay	1985