misonidazole has been researched along with Carcinoma, Epidermoid in 103 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 45 (43.69) | 18.7374 |
1990's | 13 (12.62) | 18.2507 |
2000's | 13 (12.62) | 29.6817 |
2010's | 31 (30.10) | 24.3611 |
2020's | 1 (0.97) | 2.80 |
Authors | Studies |
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Fujima, N; Hirata, K; Kudo, K; Minowa, K; Shima, T; Yamano, S | 1 |
Asaka, T; Hirata, K; Kitagawa, Y; Kuge, Y; Ohga, N; Okamoto, S; Sato, J; Shiga, T; Shindoh, M; Tamaki, N; Watanabe, S | 1 |
Bandurska-Luque, A; Baumann, M; Kotzerke, J; Krause, M; Löck, S; Perrin, R; Seidlitz, A; Steinbach, J; Troost, EGC; Zips, D; Zöphel, K; Zschaeck, S | 1 |
Asaka, T; Hirata, K; Kitagawa, Y; Ohga, N; Sato, J; Satoh, A; Shiga, T; Tamaki, N; Watanabe, S | 1 |
Agarwal, J; Budrukkar, A; Chatterjee, A; Ghosh-Laskar, S; Gupta, T; Kunder, S; Murthy, V; Purandare, N; Rangarajan, V | 1 |
Bradley, KM; Campo, L; Fenwick, JD; Gleeson, FV; Green, M; Higgins, GS; Horne, A; Macpherson, RE; Maughan, TS; McCole, MG; McGowan, DR; McKenna, WG; Mohammed, S; Muschel, RJ; Ng, SM; Panakis, N; Prevo, R; Skwarski, M; Strauss, VY; Stuart, R; Tacconi, EMC; Vallis, KA | 1 |
Hata, H; Kitagawa, Y; Kuge, Y; Okamoto, S; Sato, J; Shiga, T; Shindoh, M; Tamaki, N; Yamazaki, Y | 1 |
Alber, M; Kaanders, JH; Mönnich, D; Oyen, WJ; Thorwarth, D; Troost, EG; Zips, D | 1 |
de Clermont-Gallerande, H; Fernandez, P; Hatt, M; Henriques de Figueiredo, B; Lamare, F; Merlin, T; Vimont, D | 1 |
Baumann, M; Bergmann, R; Beuthien-Baumann, B; Brüchner, K; Hessel, F; Kotzerke, J; Krause, M; Mosch, B; Schütze, C; Steinbach, J; Thames, H; Yaromina, A; Zips, D | 1 |
Asaka, T; Hata, H; Kitagawa, Y; Kuge, Y; Miyakoshi, M; Okamoto, S; Sato, J; Shiga, T; Shindoh, M; Tamaki, N; Yamazaki, Y | 1 |
Giraud, P; Servagi-Vernat, S | 1 |
Benech, J; De Clermont-Gallerande, H; De Mones del Pujol, E; Digue, L; Fernandez, P; Galland-Girodet, S; Hatt, M; Henriques de Figueiredo, B; Lamare, F; Zacharatou, C | 1 |
Aguilera, TA; Giaccia, AJ | 1 |
Galoforo, S; Grills, IS; Kane, JL; Krueger, SA; Marples, B; Wilson, GD; Wobb, J | 1 |
Abolmaali, N; Appold, S; Baumann, M; Gudziol, V; Haase, R; Kotzerke, J; Krause, M; Perrin, R; Richter, C; Steinbach, J; Stützer, K; Zips, D; Zöphel, K; Zschaeck, S | 1 |
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Mix, M; Nestle, U; Pfeiffer, J; Vach, W; Weber, WA; Wiedenmann, NE | 1 |
la Fougère, C; Mauz, PS; Mönnich, D; Nikolaou, K; Pfannenberg, C; Reischl, G; Thorwarth, D; Welz, S; Zips, D | 1 |
Carlin, SD; Gönen, M; Grkovski, M; Humm, JL; Lee, NY; Nehmeh, SA; Schöder, H; Schwartz, J; Zanzonico, PB | 1 |
Krohn, KA; Muzi, M | 1 |
Andrzejewski, P; Baltzer, P; Georg, D; Georg, P; Grimm, C; Helbich, TH; Karanikas, G; Mitterhauser, M; Pinker, K; Poetter, R; Polanec, SH; Polterauer, S; Sturdza, A; Wadsak, W | 1 |
Baumann, M; Mönnich, D; Thorwarth, D; Wack, LJ; Yaromina, A; Zips, D | 1 |
Anzellotti, AI; Frank, JE; Hillesheim, DA; Khachaturian, MH; Merrill, JR; Yuan, H | 1 |
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Kayser, G; Meyer, PT; Mix, M; Rücker, G; Weber, WA; Werner, M; Wiedenmann, N | 1 |
Krohn, KA; Yeuh, B | 1 |
Fury, MG; Humm, JL; Jansen, JF; Koutcher, JA; Lee, NY; Pfister, DG; Schöder, H; Shukla-Dave, A; Stambuk, HE; Wang, Y | 1 |
Ando, K; Hirayama, R; Kashino, G; Kinashi, Y; Koike, S; Liu, Y; Masunaga, S; Ono, K; Suzuki, M; Takata, T; Tanaka, H; Uzawa, A | 1 |
Kikuchi, M; Senda, M; Shinohara, S; Yamane, T | 1 |
Bentzen, L; Buus, S; Keiding, S; Mortensen, LS; Munk, OL; Nordsmark, M; Overgaard, J | 1 |
Astner, ST; Bayer, C; Maftei, CA; Shi, K; Vaupel, P | 1 |
Fujiwara, K; Hori, SY; Kikuchi, M; Naito, Y; Senda, M; Shinohara, S; Tona, Y; Yamane, T; Yamazaki, H | 1 |
Dierckx, RA; Halmos, GB; Langedijk, JA; Pruim, J; Roodenburg, JL; van der Laan, BF; Wedman, J | 1 |
Anderson, NJ; Chang, JH; Gan, HK; Gong, SJ; Gunawardana, DH; Khoo, V; Lee, ST; Lim Joon, D; O'Keefe, G; Sachinidis, J; Scott, AM; Wada, M | 1 |
Ballinger, JR; Hsue, V; Rauth, AM | 1 |
Carson, J; Chan, P; Fyles, A; Milosevic, M; Pintilie, M; Rauth, M; Thomas, G | 1 |
Büll, U; Coenen, HH; Dimartino, E; Eble, MJ; Gagel, B; Hamacher, K; Maneschi, P; Pinkawa, M; Reinartz, P; Stanzel, S; Westhofen, M; Zimny, M | 1 |
Cumming, P; Horsman, MR; Keiding, S; Munk, OL; Sørensen, M | 1 |
Campa, J; Finn, R; Forster, G; Humm, J; Larson, S; Ling, C; Polycarpe-Holman, D; Zanzonico, P | 1 |
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, M; Troost, EG; van der Kogel, AJ | 1 |
Grierson, JR; Krohn, KA; Ng, P; O'Sullivan, J; Peterson, LM; Rajendran, JG; Scharnhorst, J; Schwartz, DL | 1 |
Bacharach, SL; Carson, J; Cook, JA; Eckelman, WC; English, S; Green, MV; Grimes, K; Krishna, MC; Matsumoto, K; Mitchell, JB; Seidel, J; Sowers, AL; Szajek, L | 1 |
Bamberg, M; Bares, R; Bedeshem, C; Eschmann, SM; Hehr, T; Machulla, HJ; Paulsen, F | 1 |
Asadpour, B; Coenen, HH; Demirel, C; DiMartino, E; Eble, MJ; Gagel, B; Hamacher, K; Kaiser, HJ; Maneschi, P; Pinkawa, M; Piroth, M; Reinartz, P; Scholbach, T; Stanzel, S; Zimny, M | 1 |
Byhardt, RW; Cox, JD; Greenberg, M; Komaki, R | 1 |
Ando, K; Furukawa, S; Hiraoka, T; Kanai, T; Kawachi, K; Koike, S; Majima, H | 1 |
Awwad, HK; Barsoum, M; El Badawy, S; El Baki, HA; El Merzabani, M; Ezzat, S; Omar, S; Zaki, A | 1 |
Hansen, HH; Kjaer, M; Panduro, J; Wolff-Jensen, J | 1 |
Anderson, PJ; Bennett, MH; Dische, S; Saunders, MI | 1 |
Cridland, S; Sealy, R | 1 |
Demange, L; Froissart, D; Nguyen, TD; Panis, X | 1 |
Blekkenhorst, G; Cridland, S; Korrubel, J; Sealy, R | 1 |
Abd El Baki, H; Abd El Moneim, H; Awwad, HK; El Merzabani, M; Farag, HI; Omar, S | 1 |
Omura, M | 1 |
Kishino, Y | 1 |
Okada, S; Sakamoto, K; Takada, C; Takahashi, M; Yasunaga, T | 1 |
Ho, KC; Kun, LE; Moulder, JE | 1 |
Carella, RJ; Concannon, JP; Perez, CA; Phillips, TL; Simpson, JR | 1 |
Hansen, HS; Kamieniecka, Z; Melgaard, B; Paulson, OB; Pedersen, AG; Tang, X; Trojaborg, W | 1 |
Arcangeli, G; Chaplain, G; Gonzalez, D; Horiot, JC; Svoboda, V; Van den Bogaert, W; van der Schueren, E | 1 |
Aritake, S; Sakamoto, K | 1 |
Dawes, PJ; Henk, JM; Moore, JL; Paterson, IC | 1 |
Maimonis, P; Michaels, HB; Sedlacek, R; Suit, HD | 1 |
Moore, JL; Newman, H; Paterson, IC; Venables, S | 1 |
Fazekas, JT; Goodman, RL; McLean, CJ | 1 |
Olive, PL | 3 |
Tada, T | 1 |
Abe, M; Iwai, H; Matsuno, E; Sasai, K; Shibamoto, Y | 1 |
Hori, H; Inayama, S; Mori, T; Murayama, C; Nagasawa, H; Nakajima, T; Onoyama, Y; Tada, T | 1 |
Brown, JM; Kim, IH; Lemmon, MJ | 1 |
Ebe, K; Honma, Y; Kuramitsu, T; Matsunaga, N; Miyata, Y; Nakanishi, T; Sakaguchi, M; Suda, H | 1 |
Akuta, K; Kinashi, Y; Masunaga, S; Ono, K; Suzuki, M | 1 |
Adams, GE; Horsman, MR; Khalil, AA; Overgaard, J; Steinberg, F; Stratford, IJ; Streffer, C; Wood, PJ | 1 |
Asbell, SO; Cooper, J; Grigsby, PW; Keys, H; Marcial, V; Phillips, TL; Rotman, M; Wasserman, TH; Winter, K | 1 |
Clavo, AC; Fisher, SJ; Minn, H; Wahl, RL | 1 |
D'Costa, I; Fisher, R; Hart, R; Hicks, R; Hughes, P; Peters, L; Rischin, D; Sexton, M; von Roemeling, R | 1 |
Bleehen, NM; Owen, LN; White, RA; Workman, P | 1 |
Brown, JM; Lemmon, MJ | 1 |
Cooper, J; Curran, WJ; Davis, LW; Fazekas, JT; Laramore, GE; Marcial, VA; Pajak, TF; Rubin, P | 1 |
Asbell, S; Isaacson, S; Komarnicky, LT; Martz, K; Phillips, TL; Urtasun, R | 1 |
Hammond, A; Sealy, R; Welsh, D | 1 |
Bauer, M; Byhardt, RW; Doggett, RL; Emami, B; Mowry, PA; Perez, CA; Phillips, TL; Simpson, JR; Wasserman, TH | 1 |
Fischer, JJ; Lee, DJ; Order, SE; Pajak, TF; Stetz, J; Weissberg, JB | 1 |
Andersen, AP; Berthelsen, A; Hammer, R; Hansen, HS; Hjelm-Hansen, M; Jørgensen, K; Overgaard, J; Pedersen, M; Sandberg, E | 1 |
Bentzen, SM; Bertelsen, K; Davy, M; Frankendal, B; Kjoerstad, K; Kolstad, P; Löftquist, I; Mäntyla, M; Overgaard, J; Skryten, A | 1 |
Cooper, JS; Davis, LW; Fazekas, JT; Marcial, V; Scott, C; Wasserman, T | 1 |
Durand, RE; Olive, PL | 1 |
Bauer, M; Conner, N; Cooper, J; Gillespie, B; Hornback, N; Leibel, S; Marcial, V; Pakuris, E; Rotman, M; Wasserman, T | 2 |
Okada, S; Sakamoto, K; Takai, Y | 1 |
Epp, ER; Hsieh, CC; Ngo, FQ; Roberts, WK; Sedlacek, R; Silver, G; Suit, HD; Verhey, L | 1 |
Bundy, BN; Creasman, WT; Currie, JL; Keys, H; Mortel, R; Stehman, FB | 1 |
Davis, L; Fazekas, J; Kramer, S; Marcial, V; Pajak, TF; Rotman, M; Stetz, J; Wasserman, T | 1 |
Barry, L; Blekkenhorst, G; Cridland, S; Rombouts, T; Sealy, R | 1 |
Hambraeus, GM; Lamm, IL; Landberg, T; Mercke, CE; Ranstam, J; Samuelsson, L; Willeń, R | 1 |
Akita, Y; Asakura, H; Kosaka, N; Majima, H; Suzuki, N | 1 |
Barry, L; Cridland, S; Norris, R; Sealy, R | 1 |
Bamberg, M; Brust, V; Calcanis, A; Godehard, E; Herbst, M; Karstens, JH; Kleibel, F; Makoski, HB; Prignitz, R; Scherer, E | 1 |
Hansen, HS; Hjelm Hansen, M; Jørgensen, K; Overgaard, J | 1 |
Denekamp, J; Hermeking, H; Kummermehr, J; Lindenberger, J | 1 |
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Saunders, MI; Stratford, MR; Wardman, P | 1 |
3 review(s) available for misonidazole and Carcinoma, Epidermoid
Article | Year |
---|---|
[Metabolic tailoring in radiotherapy for head and neck cancer].
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Diffusion Magnetic Resonance Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Tumor Burden | 2014 |
Novel imaging approaches to head and neck cancer.
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Diagnostic Imaging; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Oxygen; Positron-Emission Tomography | 2008 |
Alternative PET tracers in head and neck cancer. A review.
Topics: Amino Acids; Antibodies, Monoclonal; Carbon Radioisotopes; Carcinoma, Squamous Cell; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Positron-Emission Tomography; Radiopharmaceuticals | 2013 |
28 trial(s) available for misonidazole and Carcinoma, Epidermoid
Article | Year |
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Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma.
Topics: Adenocarcinoma of Lung; Aged; Aminopyridines; Anorexia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemoradiotherapy; Fatigue; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Misonidazole; Morpholines; Nausea; Phosphoinositide-3 Kinase Inhibitors; Positron Emission Tomography Computed Tomography; Radiation-Sensitizing Agents; Radiotherapy; Tumor Hypoxia | 2019 |
Potential of [18F]-fluoromisonidazole positron-emission tomography for radiotherapy planning in head and neck squamous cell carcinomas.
Topics: Aged; Carcinoma, Squamous Cell; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Reproducibility of Results; Sensitivity and Specificity; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Burden | 2013 |
Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure.
Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed | 2015 |
Serial [18F]-fluoromisonidazole PET during radiochemotherapy for locally advanced head and neck cancer and its correlation with outcome.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemoradiotherapy; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypoxia; Kaplan-Meier Estimate; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Treatment Outcome; Tumor Burden | 2015 |
Robustness of quantitative hypoxia PET image analysis for predicting local tumor control.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multicenter Studies as Topic; Positron-Emission Tomography; Radiopharmaceuticals; ROC Curve; Squamous Cell Carcinoma of Head and Neck | 2015 |
Reduction of [(18)F]fluoromisonidazole uptake after neoadjuvant chemotherapy for head and neck squamous cell carcinoma.
Topics: Aged; Carcinoma, Squamous Cell; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Lymph Nodes; Male; Middle Aged; Misonidazole; Neoadjuvant Therapy; Positron-Emission Tomography; Treatment Outcome | 2011 |
A phase III randomized study of misonidazole plus radiation vs. radiation alone for cervix cancer.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Disease-Free Survival; Double-Blind Method; Female; Humans; Misonidazole; Radiation-Sensitizing Agents; Radiotherapy Dosage; Survival Rate; Uterine Cervical Neoplasms | 2004 |
pO(2) Polarography versus positron emission tomography ([(18)F] fluoromisonidazole, [(18)F]-2-fluoro-2'-deoxyglucose). An appraisal of radiotherapeutically relevant hypoxia.
Topics: Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Misonidazole; Oximetry; Oxygen; Oxygen Consumption; Polarography; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2004 |
Misonidazole combined with radiotherapy in the treatment of inoperable squamous cell carcinoma of the lung. A double-blind randomized trial.
Topics: Aged; Carcinoma, Squamous Cell; Double-Blind Method; Esophagitis; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Placebos; Pneumonia; Radiation Injuries; Radiotherapy Dosage; Random Allocation; Vomiting | 1983 |
A study of the effect of misonidazole in conjunction with radiotherapy for the treatment of head and neck cancer. MRC working party on misonidazole in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Radiotherapy; Radiotherapy Dosage; Random Allocation | 1984 |
Primary tumor control after radiotherapy for carcinoma of the bronchus.
Topics: Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Double-Blind Method; Humans; Misonidazole; Neoplasm Metastasis; Nitroimidazoles; Radiation Tolerance | 1984 |
The treatment of locally advanced head and neck cancer with misonidazole, hyperbaric oxygen and irradiation: an interim report.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation | 1984 |
Hyperfractionated radiotherapy with or without misonidazole: results of a prospective randomized study in stage III-IV squamous cell carcinoma of the head and neck.
Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cobalt Radioisotopes; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Radioisotope Teletherapy; Radiotherapy Dosage; Random Allocation | 1984 |
Irradiation with or without misonidazole for patients with stages IIIB and IVA carcinoma of the cervix: final results of RTOG 80-05. Radiation Therapy Oncology Group.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Humans; Middle Aged; Misonidazole; Neoplasm Staging; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Failure; Uterine Cervical Neoplasms | 1999 |
Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Hypoxia; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Administration Schedule; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Middle Aged; Misonidazole; Radiation-Sensitizing Agents; Radiopharmaceuticals; Survival Analysis; Tirapazamine; Tomography, Emission-Computed; Triazines | 2001 |
Elapsed treatment days--a critical item for radiotherapy quality control review in head and neck trials: RTOG report.
Topics: Carcinoma, Squamous Cell; Clinical Protocols; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Misonidazole; Outcome and Process Assessment, Health Care; Radiation-Sensitizing Agents | 1991 |
A randomized phase III protocol for the evaluation of misonidazole combined with radiation in the treatment of patients with brain metastases (RTOG-7916).
Topics: Adenocarcinoma; Adult; Aged; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Prospective Studies; Radiation-Sensitizing Agents; Survival Analysis | 1991 |
Radiation therapy alone or combined with misonidazole in the treatment of locally advanced non-oat cell lung cancer: report of an RTOG prospective randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Lung Neoplasms; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prognosis; Prospective Studies; Random Allocation | 1989 |
A phase I/II study of the hypoxic cell sensitizer misonidazole as an adjunct to high fractional dose radiotherapy in patients with unresectable squamous cell carcinoma of the head and neck: a RTOG randomized study (#79-04).
Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prospective Studies; Radiotherapy; Radiotherapy Dosage; Random Allocation | 1989 |
Misonidazole combined with split-course radiotherapy in the treatment of invasive carcinoma of larynx and pharynx: report from the DAHANCA 2 study.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Double-Blind Method; Female; Humans; Laryngeal Neoplasms; Male; Misonidazole; Multicenter Studies as Topic; Neoplasm Invasiveness; Pharyngeal Neoplasms; Prognosis; Random Allocation | 1989 |
Misonidazole combined with radiotherapy in the treatment of carcinoma of the uterine cervix.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Double-Blind Method; Female; Humans; Misonidazole; Multicenter Studies as Topic; Random Allocation; Uterine Cervical Neoplasms | 1989 |
The role of hemoglobin concentration in the outcome of misonidazole-sensitized radiotherapy of head and neck cancers: based on RTOG trial #79-15.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Hemoglobins; Humans; Male; Misonidazole; Multicenter Studies as Topic; United States | 1989 |
Radiotherapy with or without misonidazole for patients with stage IIIB or stage IVA squamous cell carcinoma of the uterine cervix: preliminary report of a Radiation Therapy Oncology Group randomized trial.
Topics: Adolescent; Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Humans; Middle Aged; Misonidazole; Radiotherapy; Radiotherapy, High-Energy; Random Allocation; Uterine Cervical Neoplasms | 1987 |
A randomized trial of hydroxyurea versus misonidazole adjunct to radiation therapy in carcinoma of the cervix. A preliminary report of a Gynecologic Oncology Group study.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Hydroxyurea; Middle Aged; Misonidazole; Random Allocation; Uterine Cervical Neoplasms | 1988 |
Failure of misonidazole-sensitized radiotherapy to impact upon outcome among stage III-IV squamous cancers of the head and neck.
Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation | 1987 |
Effect of misonidazole dose on survival in patients with stage IIIB-IVA squamous cell carcinoma of the uterine cervix: an RTOG randomized trial.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation; Uterine Cervical Neoplasms | 1986 |
Irradiation with misonidazole and hyperbaric oxygen: final report on a randomized trial in advanced head and neck cancer.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Misonidazole; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation | 1986 |
[Esophageal carcinoma: the final results of a multicenter and controlled German study with misonidazole and radiation].
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Esophageal Neoplasms; Esophagus; Female; Humans; Male; Middle Aged; Misonidazole; Neoplasm Staging; Prospective Studies; Radiotherapy Dosage; Random Allocation | 1986 |
72 other study(ies) available for misonidazole and Carcinoma, Epidermoid
Article | Year |
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Evaluation of non-Gaussian model-based diffusion-weighted imaging in oral squamous cell carcinoma: comparison with tumour functional information derived from positron-emission tomography.
Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Diffusion Magnetic Resonance Imaging; Female; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals | 2020 |
Topics: Adult; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Proliferation; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Hypoxia | 2017 |
Residual tumour hypoxia in head-and-neck cancer patients undergoing primary radiochemotherapy, final results of a prospective trial on repeat FMISO-PET imaging.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prospective Studies; Squamous Cell Carcinoma of Head and Neck; Tumor Burden | 2017 |
Hypoxic volume evaluated by
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Neck Dissection; Neoplasm Grading; Neoplasm Recurrence, Local; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Survival Rate; Treatment Outcome; Tumor Hypoxia | 2018 |
Optimal timing of fluorine-18-fluoromisonidazole positron emission tomography/computed tomography for assessment of tumor hypoxia in patients with head and neck squamous cell carcinoma.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Positron Emission Tomography Computed Tomography; Time Factors; Tumor Hypoxia; Young Adult | 2018 |
18F-fluoromisonidazole PET uptake is correlated with hypoxia-inducible factor-1α expression in oral squamous cell carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic | 2013 |
Correlation between tumor oxygenation and 18F-fluoromisonidazole PET data simulated based on microvessel images.
Topics: Animals; Carcinoma, Squamous Cell; Computer Simulation; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Mice; Microvessels; Misonidazole; Oxygen; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Cells, Cultured | 2013 |
Effect of [(18)F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Radiation-Sensitizing Agents; Radionuclide Imaging; Radiopharmaceuticals; Random Allocation; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays | 2014 |
Advantage of FMISO-PET over FDG-PET for predicting histological response to preoperative chemotherapy in patients with oral squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Positron-Emission Tomography; Preoperative Period; Treatment Outcome | 2014 |
Hypoxia imaging with [18F]-FMISO-PET for guided dose escalation with intensity-modulated radiotherapy in head-and-neck cancers.
Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Humans; Male; Middle Aged; Misonidazole; Neoplasm Staging; Otorhinolaryngologic Neoplasms; Positron-Emission Tomography; Prognosis; Radiotherapy; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Tumor Burden | 2015 |
The end of the hypoxic EPOch.
Topics: Anemia; Blood Transfusion; Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Erythropoietin; Etanidazole; Female; Head and Neck Neoplasms; Humans; Male; Misonidazole; Radiation-Sensitizing Agents; Receptors, Erythropoietin; Treatment Failure; Uterine Cervical Neoplasms | 2015 |
The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Heterografts; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden | 2015 |
Feasibility of 18F-Fluoromisonidazole Kinetic Modeling in Head and Neck Cancer Using Shortened Acquisition Times.
Topics: Algorithms; Animals; Carcinoma, Squamous Cell; Cohort Studies; Colorectal Neoplasms; Head and Neck Neoplasms; HT29 Cells; Humans; Hypoxia; Image Processing, Computer-Assisted; Misonidazole; Neoplasm Transplantation; Perfusion; Radionuclide Imaging; Radiopharmaceuticals; Rats; Reproducibility of Results; Retrospective Studies; ROC Curve | 2016 |
Imaging Hypoxia with ¹⁸F-Fluoromisonidazole: Challenges in Moving to a More Complicated Analysis.
Topics: Animals; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Misonidazole; Radionuclide Imaging; Radiopharmaceuticals | 2016 |
Multiparametric [18F]Fluorodeoxyglucose/ [18F]Fluoromisonidazole Positron Emission Tomography/ Magnetic Resonance Imaging of Locally Advanced Cervical Cancer for the Non-Invasive Detection of Tumor Heterogeneity: A Pilot Study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Middle Aged; Misonidazole; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Retrospective Studies; Tumor Burden; Uterine Cervical Neoplasms | 2016 |
Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O2 consumption?
Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Computer Simulation; Feasibility Studies; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Hypoxia; Mice, Nude; Misonidazole; Models, Biological; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment | 2016 |
Automated PET Radiotracer Manufacture on the BG75 System and Imaging Validation Studies of [18F]fluoromisonidazole ([18F]FMISO).
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chromatography, High Pressure Liquid; Glioblastoma; Humans; Mice; Misonidazole; Positron Emission Tomography Computed Tomography; Radiographic Image Interpretation, Computer-Assisted; Radiopharmaceuticals; Tissue Distribution | 2016 |
Analysis of relation between hypoxia PET imaging and tissue-based biomarkers during head and neck radiochemotherapy.
Topics: Adult; Aged; Biomarkers, Tumor; Carbonic Anhydrase IX; Carcinoma, Squamous Cell; Chemoradiotherapy; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Immunohistochemistry; Ku Autoantigen; Male; Middle Aged; Misonidazole; Papillomavirus Infections; Positron-Emission Tomography; Proportional Hazards Models; Radiopharmaceuticals; Tomography, X-Ray Computed; Tumor Hypoxia | 2016 |
Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases.
Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Retrospective Studies; Statistics, Nonparametric | 2010 |
Influence of manipulating hypoxia in solid tumors on the radiation dose-rate effect in vivo, with reference to that in the quiescent cell population.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Carbon Radioisotopes; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Fluorescent Antibody Technique; Gamma Rays; Mice; Mice, Inbred C3H; Misonidazole; Niacinamide; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Vitamin B Complex | 2010 |
Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode.
Topics: Biosensing Techniques; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Hypoxia; Microchemistry; Microelectrodes; Misonidazole; Neoplasms; Oxygen; Positron-Emission Tomography; Sarcoma; Soft Tissue Neoplasms | 2010 |
Comparison of (immuno-)fluorescence data with serial [¹⁸F]Fmiso PET/CT imaging for assessment of chronic and acute hypoxia in head and neck cancers.
Topics: Acute Disease; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chronic Disease; Disease Progression; Head and Neck Neoplasms; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Mice; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Radiation-Sensitizing Agents; Tomography, X-Ray Computed; Transplantation, Heterologous | 2011 |
18F-fluoromisonidazole positron emission tomography before treatment is a predictor of radiotherapy outcome and survival prognosis in patients with head and neck squamous cell carcinoma.
Topics: Adult; Aged; Analysis of Variance; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome | 2011 |
Hypoxia-targeted radiotherapy dose painting for head and neck cancer using (18)F-FMISO PET: a biological modeling study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Cohort Studies; Fluorodeoxyglucose F18; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Models, Biological; Neoplasm Staging; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated | 2013 |
Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models.
Topics: Animals; Azides; Carcinoma, Squamous Cell; CHO Cells; Cricetinae; Cricetulus; Fibrosarcoma; Fructose; Glucaric Acid; Hypoxia; Male; Metabolic Clearance Rate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Organotechnetium Compounds; Oxygen; Potassium Cyanide; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution | 2003 |
Effect of intratumoral heterogeneity in oxygenation status on FMISO PET, autoradiography, and electrode Po2 measurements in murine tumors.
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Oxygen Consumption; Partial Pressure; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals | 2005 |
Animal-specific positioning molds for registration of repeat imaging studies: comparative microPET imaging of F18-labeled fluoro-deoxyglucose and fluoro-misonidazole in rodent tumors.
Topics: Animals; Carcinoma, Squamous Cell; Equipment Design; Equipment Failure Analysis; Fluorodeoxyglucose F18; Humans; Male; Misonidazole; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Rats; Reproducibility of Results; Restraint, Physical; Sensitivity and Specificity; Species Specificity; Subtraction Technique | 2006 |
Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Glioblastoma; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging | 2006 |
Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer.
Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorodeoxyglucose F18; Follow-Up Studies; Head and Neck Neoplasms; Humans; Middle Aged; Misonidazole; Multivariate Analysis; Positron-Emission Tomography; Survival Analysis | 2006 |
The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coordination Complexes; Mice; Misonidazole; Neoplasm Transplantation; Organometallic Compounds; Oxygen; Positron-Emission Tomography; Thiosemicarbazones | 2007 |
Hypoxia-imaging with (18)F-Misonidazole and PET: changes of kinetics during radiotherapy of head-and-neck cancer.
Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Kinetics; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prospective Studies; Radiation-Sensitizing Agents | 2007 |
pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle o
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Misonidazole; Oxygen Consumption; Polarography; Positron-Emission Tomography; Prognosis; Ultrasonography, Doppler, Color | 2007 |
Reduced fractionation and the potential of hypoxic cell sensitizers in irradiation of malignant epithelial tumors.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Misonidazole; Mouth Neoplasms; Nitroimidazoles; Oropharynx; Pharyngeal Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Retrospective Studies | 1980 |
[Biological studies of proton irradiation under combination with a hypoxic cell sensitizer].
Topics: Animals; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Protons; Radiotherapy, High-Energy; Skin Neoplasms | 1982 |
The use of misonidazole in association with a three-fractions per day regimen in advanced head and neck epidermoid cancer. A pilot study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Erythema; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Pilot Projects; Radiotherapy Dosage | 1983 |
Interstitial misonidazole. A preliminary report on a new perspective in clinical radiation sensitization and hypoxic cell chemotherapy.
Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Injections; Male; Melanoma; Middle Aged; Misonidazole; Nitroimidazoles; Skin Neoplasms | 1984 |
The topical use of misonidazole in bladder cancer.
Topics: Administration, Oral; Administration, Topical; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Humans; Kinetics; Misonidazole; Mucous Membrane; Nitroimidazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
[Experimental studies on radiosensitization of hypoxic cancer cells].
Topics: Animals; Carcinoma, Squamous Cell; Female; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Uterine Cervical Neoplasms | 1983 |
[Flow-microfluorometric studies on the effect of misonidazole as a radiosensitizer for human uterine cervical carcinoma transplanted to nude mice].
Topics: Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Flow Cytometry; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Uterine Cervical Neoplasms | 1983 |
[Effect of even or uneven dose fractionation regime on murine squamous cell carcinoma with combined use of misonidazole].
Topics: Animals; Carcinoma, Squamous Cell; Combined Modality Therapy; Fibrosarcoma; Mice; Mice, Inbred Strains; Misonidazole; Nitroimidazoles; Radiotherapy Dosage | 1983 |
Fatal misonidazole-induced encephalopathy: an RTOG case report.
Topics: Brain Diseases; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Palatal Neoplasms; Tongue Neoplasms | 1982 |
Large fraction radiotherapy plus misonidazole for treatment of advanced lung cancer: report of a phase I/II trial.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Radiotherapy; Radiotherapy Dosage | 1982 |
Misonidazole Neuropathy: a clinical, electrophysiological, and histological study.
Topics: Aged; Carcinoma, Squamous Cell; Electromyography; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Median Nerve; Middle Aged; Misonidazole; Nerve Fibers, Myelinated; Nervous System Diseases; Neural Conduction; Neuromuscular Diseases; Nitroimidazoles; Paresthesia; Peroneal Nerve; Pharyngeal Neoplasms; Sensation; Sural Nerve; Tibial Nerve | 1982 |
The feasibility of high-dose multiple daily fractionation and its combination with anoxic cell sensitizers in the treatment of head and neck cancer. A pilot study of the Radiotherapy Group of the EORTC (European Organisation for Research on Treatment of C
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prognosis; Radiotherapy Dosage | 1982 |
Effects of misonidazole on tumor cell radiation sensitivity and potentially lethal damage repair in vivo and in vitro.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Time Factors | 1981 |
Pilot study of radiotherapy with misonidazole in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Pilot Projects; Radiotherapy Dosage | 1981 |
Comparison of hyperbaric oxygen and misonidazole in fractionated irradiation of murine tumors.
Topics: Animals; Carcinoma, Squamous Cell; Female; Hyperbaric Oxygenation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Skin | 1981 |
Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients.
Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Half-Life; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Nitroimidazoles; Phenytoin; Time Factors | 1981 |
The value of adjuvant misonidazole in the definitive irradiation of advanced head and neck squamous cancer: an RTOG pilot study (#78-02).
Topics: Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Nausea; Neoplasm Recurrence, Local; Neoplasm Staging; Nitroimidazoles; Paresthesia; Pharyngeal Neoplasms; Prognosis | 1981 |
Use of the comet assay to detect hypoxic cells in murine tumours and normal tissues exposed to bioreductive drugs.
Topics: Aerobiosis; Animals; Antineoplastic Agents; Bone Marrow; Carcinoma, Squamous Cell; Cell Hypoxia; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Electrophoresis, Agar Gel; Hydrogen-Ion Concentration; Male; Mice; Mice, Inbred C3H; Misonidazole; Organ Specificity; Oxidation-Reduction; Radiation-Sensitizing Agents; Spleen; Tirapazamine; Triazines | 1995 |
Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. II. RSU 1069.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Damage; DNA Repair; DNA, Neoplasm; Fibroblasts; Flow Cytometry; Kinetics; Male; Mice; Mice, Inbred C3H; Misonidazole | 1995 |
[Radiosensitizing effects of nitroimidazole derivative, KIN-804].
Topics: Animals; Carcinoma, Squamous Cell; Hydroxamic Acids; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms | 1995 |
Radiosensitizing activity and pharmacokinetics of multiple dose administered KU-2285 in peripheral nerve tissue in mice.
Topics: Animals; Carcinoma, Squamous Cell; Etanidazole; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Peripheral Nerves; Radiation-Sensitizing Agents | 1994 |
In vivo radiosensitizing effect of nitroimidazole derivative KIN-804.
Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Hydroxamic Acids; Lethal Dose 50; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents | 1994 |
The influence of irradiation of the tumor bed on tumor hypoxia: measurements by radiation response, oxygen electrodes, and nitroimidazole binding.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen; Partial Pressure; Sarcoma; Tumor Cells, Cultured | 1993 |
Evaluation of the radiosensitizing effects of RK28 intravenous, intraarterial, and intratumoral injections on the rabbit VX2 tumor system.
Topics: Animals; Carcinoma, Squamous Cell; Injections, Intra-Arterial; Injections, Intravenous; Male; Misonidazole; Neoplasms, Experimental; Rabbits; Radiation-Sensitizing Agents | 1996 |
The radiosensitizing effects of hypoxic cell sensitizer on SCCVII tumors in mice evaluated by highly accurate colony formation assay assisted by microcomputer.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Etanidazole; Male; Mice; Mice, Inbred C3H; Microcomputers; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
A comparison of the physiological effects of RSU1069 and RB6145 in the SCCVII murine tumour.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C3H; Misonidazole; Neovascularization, Pathologic; Nitroimidazoles; Oxygen; Phosphorus Radioisotopes | 1996 |
Effect of nitroimidazole sensitizers on in vitro glycolytic metabolism of hypoxic squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Death; Cell Hypoxia; Fluorodeoxyglucose F18; Humans; Misonidazole; Nimorazole; Radiation-Sensitizing Agents; Tomography, Emission-Computed; Tritium; Tumor Cells, Cultured | 2000 |
The penetration of misonidazole into spontaneous canine tumours.
Topics: Adenocarcinoma; Anesthesia, Intravenous; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Dog Diseases; Dogs; Female; Fibrosarcoma; Half-Life; Lymphoma, Non-Hodgkin; Male; Mammary Glands, Animal; Meningioma; Misonidazole; Neoplasms; Nitroimidazoles; Osteosarcoma; Pentobarbital | 1979 |
Hydralazine does not increase hypoxia in tumors growing in preirradiated tissue.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Squamous Cell; Cell Hypoxia; Drug Administration Schedule; Female; Hydralazine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Radiotherapy Dosage | 1991 |
Palliative topical and systemic misonidazole with low-dose irradiation for recurrent carcinoma of the cervix uteri.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Misonidazole; Neoplasm Recurrence, Local; Palliative Care; Radiotherapy Dosage; Uterine Cervical Neoplasms | 1986 |
Distribution, oxygenation, and clonogenicity of macrophages in a murine tumor.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Survival; DNA Replication; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Macrophages; Mice; Mice, Inbred C3H; Misonidazole; Reference Values; Thymidine; Tritium | 1989 |
Misonidazole binding in SCCVII tumors in relation to the tumor blood supply.
Topics: Animals; Carcinoma, Squamous Cell; Cell Separation; Flow Cytometry; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen | 1989 |
Oxic and hypoxic cells in a murine squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Constriction; Dose-Response Relationship, Radiation; Female; Hypoxia; Idoxuridine; Iodine Radioisotopes; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Oxygen Consumption; Skin Neoplasms | 1988 |
Therapeutic gain factors for fractionated radiation treatment of spontaneous murine tumors using fast neutrons, photons plus O2(1) or 3 ATA, or photons plus misonidazole.
Topics: Animals; Carcinoma, Squamous Cell; Combined Modality Therapy; Fast Neutrons; Female; Fibrosarcoma; Hyperbaric Oxygenation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen; Radiotherapy Dosage | 1988 |
Interstitial misonidazole: clinical experience in advanced mouth cancer.
Topics: Animals; Carcinoma, Squamous Cell; Drug Implants; Humans; Misonidazole; Mouth Neoplasms; Needles; Neoplasm Recurrence, Local; Swine | 1988 |
Prognostic factors influencing survival in combined radiotherapy and surgery of squamous cell carcinoma of the esophagus with special reference to a histopathologic grading system.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Esophageal Neoplasms; Humans; Misonidazole; Prognosis; Time Factors | 1988 |
[Enhancement of radiation response of SqII mouse tumors by combined treatment with misonidazole, vidarabine, and ACNU].
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Male; Mice; Misonidazole; Nimustine; Nitrosourea Compounds; Vidarabine | 1987 |
Primary radiotherapy of larynx and pharynx carcinoma--an analysis of some factors influencing local control and survival.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Hemoglobins; Humans; Laryngeal Neoplasms; Male; Misonidazole; Pharyngeal Neoplasms; Prognosis | 1986 |
Response of human tumour xenografts to fractionated X-irradiation.
Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Humans; Male; Mice; Mice, Nude; Misonidazole; Mouth Neoplasms; Neoplasm Transplantation; Photochemotherapy; Radiotherapy Dosage; Tonsillar Neoplasms; Transplantation, Heterologous | 1986 |
A comparison of the tumour concentrations obtainable with misonidazole and Ro 03-8799.
Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cricetinae; Cricetulus; Female; Humans; Male; Melanoma; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1986 |