Page last updated: 2024-08-22

misonidazole and Carcinoma, Epidermoid

misonidazole has been researched along with Carcinoma, Epidermoid in 103 studies

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-199045 (43.69)18.7374
1990's13 (12.62)18.2507
2000's13 (12.62)29.6817
2010's31 (30.10)24.3611
2020's1 (0.97)2.80

Authors

AuthorsStudies
Fujima, N; Hirata, K; Kudo, K; Minowa, K; Shima, T; Yamano, S1
Asaka, T; Hirata, K; Kitagawa, Y; Kuge, Y; Ohga, N; Okamoto, S; Sato, J; Shiga, T; Shindoh, M; Tamaki, N; Watanabe, S1
Bandurska-Luque, A; Baumann, M; Kotzerke, J; Krause, M; Löck, S; Perrin, R; Seidlitz, A; Steinbach, J; Troost, EGC; Zips, D; Zöphel, K; Zschaeck, S1
Asaka, T; Hirata, K; Kitagawa, Y; Ohga, N; Sato, J; Satoh, A; Shiga, T; Tamaki, N; Watanabe, S1
Agarwal, J; Budrukkar, A; Chatterjee, A; Ghosh-Laskar, S; Gupta, T; Kunder, S; Murthy, V; Purandare, N; Rangarajan, V1
Bradley, KM; Campo, L; Fenwick, JD; Gleeson, FV; Green, M; Higgins, GS; Horne, A; Macpherson, RE; Maughan, TS; McCole, MG; McGowan, DR; McKenna, WG; Mohammed, S; Muschel, RJ; Ng, SM; Panakis, N; Prevo, R; Skwarski, M; Strauss, VY; Stuart, R; Tacconi, EMC; Vallis, KA1
Hata, H; Kitagawa, Y; Kuge, Y; Okamoto, S; Sato, J; Shiga, T; Shindoh, M; Tamaki, N; Yamazaki, Y1
Alber, M; Kaanders, JH; Mönnich, D; Oyen, WJ; Thorwarth, D; Troost, EG; Zips, D1
de Clermont-Gallerande, H; Fernandez, P; Hatt, M; Henriques de Figueiredo, B; Lamare, F; Merlin, T; Vimont, D1
Baumann, M; Bergmann, R; Beuthien-Baumann, B; Brüchner, K; Hessel, F; Kotzerke, J; Krause, M; Mosch, B; Schütze, C; Steinbach, J; Thames, H; Yaromina, A; Zips, D1
Asaka, T; Hata, H; Kitagawa, Y; Kuge, Y; Miyakoshi, M; Okamoto, S; Sato, J; Shiga, T; Shindoh, M; Tamaki, N; Yamazaki, Y1
Giraud, P; Servagi-Vernat, S1
Benech, J; De Clermont-Gallerande, H; De Mones del Pujol, E; Digue, L; Fernandez, P; Galland-Girodet, S; Hatt, M; Henriques de Figueiredo, B; Lamare, F; Zacharatou, C1
Aguilera, TA; Giaccia, AJ1
Galoforo, S; Grills, IS; Kane, JL; Krueger, SA; Marples, B; Wilson, GD; Wobb, J1
Abolmaali, N; Appold, S; Baumann, M; Gudziol, V; Haase, R; Kotzerke, J; Krause, M; Perrin, R; Richter, C; Steinbach, J; Stützer, K; Zips, D; Zöphel, K; Zschaeck, S1
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Mix, M; Nestle, U; Pfeiffer, J; Vach, W; Weber, WA; Wiedenmann, NE1
la Fougère, C; Mauz, PS; Mönnich, D; Nikolaou, K; Pfannenberg, C; Reischl, G; Thorwarth, D; Welz, S; Zips, D1
Carlin, SD; Gönen, M; Grkovski, M; Humm, JL; Lee, NY; Nehmeh, SA; Schöder, H; Schwartz, J; Zanzonico, PB1
Krohn, KA; Muzi, M1
Andrzejewski, P; Baltzer, P; Georg, D; Georg, P; Grimm, C; Helbich, TH; Karanikas, G; Mitterhauser, M; Pinker, K; Poetter, R; Polanec, SH; Polterauer, S; Sturdza, A; Wadsak, W1
Baumann, M; Mönnich, D; Thorwarth, D; Wack, LJ; Yaromina, A; Zips, D1
Anzellotti, AI; Frank, JE; Hillesheim, DA; Khachaturian, MH; Merrill, JR; Yuan, H1
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Kayser, G; Meyer, PT; Mix, M; Rücker, G; Weber, WA; Werner, M; Wiedenmann, N1
Krohn, KA; Yeuh, B1
Fury, MG; Humm, JL; Jansen, JF; Koutcher, JA; Lee, NY; Pfister, DG; Schöder, H; Shukla-Dave, A; Stambuk, HE; Wang, Y1
Ando, K; Hirayama, R; Kashino, G; Kinashi, Y; Koike, S; Liu, Y; Masunaga, S; Ono, K; Suzuki, M; Takata, T; Tanaka, H; Uzawa, A1
Kikuchi, M; Senda, M; Shinohara, S; Yamane, T1
Bentzen, L; Buus, S; Keiding, S; Mortensen, LS; Munk, OL; Nordsmark, M; Overgaard, J1
Astner, ST; Bayer, C; Maftei, CA; Shi, K; Vaupel, P1
Fujiwara, K; Hori, SY; Kikuchi, M; Naito, Y; Senda, M; Shinohara, S; Tona, Y; Yamane, T; Yamazaki, H1
Dierckx, RA; Halmos, GB; Langedijk, JA; Pruim, J; Roodenburg, JL; van der Laan, BF; Wedman, J1
Anderson, NJ; Chang, JH; Gan, HK; Gong, SJ; Gunawardana, DH; Khoo, V; Lee, ST; Lim Joon, D; O'Keefe, G; Sachinidis, J; Scott, AM; Wada, M1
Ballinger, JR; Hsue, V; Rauth, AM1
Carson, J; Chan, P; Fyles, A; Milosevic, M; Pintilie, M; Rauth, M; Thomas, G1
Büll, U; Coenen, HH; Dimartino, E; Eble, MJ; Gagel, B; Hamacher, K; Maneschi, P; Pinkawa, M; Reinartz, P; Stanzel, S; Westhofen, M; Zimny, M1
Cumming, P; Horsman, MR; Keiding, S; Munk, OL; Sørensen, M1
Campa, J; Finn, R; Forster, G; Humm, J; Larson, S; Ling, C; Polycarpe-Holman, D; Zanzonico, P1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, M; Troost, EG; van der Kogel, AJ1
Grierson, JR; Krohn, KA; Ng, P; O'Sullivan, J; Peterson, LM; Rajendran, JG; Scharnhorst, J; Schwartz, DL1
Bacharach, SL; Carson, J; Cook, JA; Eckelman, WC; English, S; Green, MV; Grimes, K; Krishna, MC; Matsumoto, K; Mitchell, JB; Seidel, J; Sowers, AL; Szajek, L1
Bamberg, M; Bares, R; Bedeshem, C; Eschmann, SM; Hehr, T; Machulla, HJ; Paulsen, F1
Asadpour, B; Coenen, HH; Demirel, C; DiMartino, E; Eble, MJ; Gagel, B; Hamacher, K; Kaiser, HJ; Maneschi, P; Pinkawa, M; Piroth, M; Reinartz, P; Scholbach, T; Stanzel, S; Zimny, M1
Byhardt, RW; Cox, JD; Greenberg, M; Komaki, R1
Ando, K; Furukawa, S; Hiraoka, T; Kanai, T; Kawachi, K; Koike, S; Majima, H1
Awwad, HK; Barsoum, M; El Badawy, S; El Baki, HA; El Merzabani, M; Ezzat, S; Omar, S; Zaki, A1
Hansen, HH; Kjaer, M; Panduro, J; Wolff-Jensen, J1
Anderson, PJ; Bennett, MH; Dische, S; Saunders, MI1
Cridland, S; Sealy, R1
Demange, L; Froissart, D; Nguyen, TD; Panis, X1
Blekkenhorst, G; Cridland, S; Korrubel, J; Sealy, R1
Abd El Baki, H; Abd El Moneim, H; Awwad, HK; El Merzabani, M; Farag, HI; Omar, S1
Omura, M1
Kishino, Y1
Okada, S; Sakamoto, K; Takada, C; Takahashi, M; Yasunaga, T1
Ho, KC; Kun, LE; Moulder, JE1
Carella, RJ; Concannon, JP; Perez, CA; Phillips, TL; Simpson, JR1
Hansen, HS; Kamieniecka, Z; Melgaard, B; Paulson, OB; Pedersen, AG; Tang, X; Trojaborg, W1
Arcangeli, G; Chaplain, G; Gonzalez, D; Horiot, JC; Svoboda, V; Van den Bogaert, W; van der Schueren, E1
Aritake, S; Sakamoto, K1
Dawes, PJ; Henk, JM; Moore, JL; Paterson, IC1
Maimonis, P; Michaels, HB; Sedlacek, R; Suit, HD1
Moore, JL; Newman, H; Paterson, IC; Venables, S1
Fazekas, JT; Goodman, RL; McLean, CJ1
Olive, PL3
Tada, T1
Abe, M; Iwai, H; Matsuno, E; Sasai, K; Shibamoto, Y1
Hori, H; Inayama, S; Mori, T; Murayama, C; Nagasawa, H; Nakajima, T; Onoyama, Y; Tada, T1
Brown, JM; Kim, IH; Lemmon, MJ1
Ebe, K; Honma, Y; Kuramitsu, T; Matsunaga, N; Miyata, Y; Nakanishi, T; Sakaguchi, M; Suda, H1
Akuta, K; Kinashi, Y; Masunaga, S; Ono, K; Suzuki, M1
Adams, GE; Horsman, MR; Khalil, AA; Overgaard, J; Steinberg, F; Stratford, IJ; Streffer, C; Wood, PJ1
Asbell, SO; Cooper, J; Grigsby, PW; Keys, H; Marcial, V; Phillips, TL; Rotman, M; Wasserman, TH; Winter, K1
Clavo, AC; Fisher, SJ; Minn, H; Wahl, RL1
D'Costa, I; Fisher, R; Hart, R; Hicks, R; Hughes, P; Peters, L; Rischin, D; Sexton, M; von Roemeling, R1
Bleehen, NM; Owen, LN; White, RA; Workman, P1
Brown, JM; Lemmon, MJ1
Cooper, J; Curran, WJ; Davis, LW; Fazekas, JT; Laramore, GE; Marcial, VA; Pajak, TF; Rubin, P1
Asbell, S; Isaacson, S; Komarnicky, LT; Martz, K; Phillips, TL; Urtasun, R1
Hammond, A; Sealy, R; Welsh, D1
Bauer, M; Byhardt, RW; Doggett, RL; Emami, B; Mowry, PA; Perez, CA; Phillips, TL; Simpson, JR; Wasserman, TH1
Fischer, JJ; Lee, DJ; Order, SE; Pajak, TF; Stetz, J; Weissberg, JB1
Andersen, AP; Berthelsen, A; Hammer, R; Hansen, HS; Hjelm-Hansen, M; Jørgensen, K; Overgaard, J; Pedersen, M; Sandberg, E1
Bentzen, SM; Bertelsen, K; Davy, M; Frankendal, B; Kjoerstad, K; Kolstad, P; Löftquist, I; Mäntyla, M; Overgaard, J; Skryten, A1
Cooper, JS; Davis, LW; Fazekas, JT; Marcial, V; Scott, C; Wasserman, T1
Durand, RE; Olive, PL1
Bauer, M; Conner, N; Cooper, J; Gillespie, B; Hornback, N; Leibel, S; Marcial, V; Pakuris, E; Rotman, M; Wasserman, T2
Okada, S; Sakamoto, K; Takai, Y1
Epp, ER; Hsieh, CC; Ngo, FQ; Roberts, WK; Sedlacek, R; Silver, G; Suit, HD; Verhey, L1
Bundy, BN; Creasman, WT; Currie, JL; Keys, H; Mortel, R; Stehman, FB1
Davis, L; Fazekas, J; Kramer, S; Marcial, V; Pajak, TF; Rotman, M; Stetz, J; Wasserman, T1
Barry, L; Blekkenhorst, G; Cridland, S; Rombouts, T; Sealy, R1
Hambraeus, GM; Lamm, IL; Landberg, T; Mercke, CE; Ranstam, J; Samuelsson, L; Willeń, R1
Akita, Y; Asakura, H; Kosaka, N; Majima, H; Suzuki, N1
Barry, L; Cridland, S; Norris, R; Sealy, R1
Bamberg, M; Brust, V; Calcanis, A; Godehard, E; Herbst, M; Karstens, JH; Kleibel, F; Makoski, HB; Prignitz, R; Scherer, E1
Hansen, HS; Hjelm Hansen, M; Jørgensen, K; Overgaard, J1
Denekamp, J; Hermeking, H; Kummermehr, J; Lindenberger, J1
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Saunders, MI; Stratford, MR; Wardman, P1

Reviews

3 review(s) available for misonidazole and Carcinoma, Epidermoid

ArticleYear
[Metabolic tailoring in radiotherapy for head and neck cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Diffusion Magnetic Resonance Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Tumor Burden

2014
Novel imaging approaches to head and neck cancer.
    Seminars in oncology, 2008, Volume: 35, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Diagnostic Imaging; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Oxygen; Positron-Emission Tomography

2008
Alternative PET tracers in head and neck cancer. A review.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:10

    Topics: Amino Acids; Antibodies, Monoclonal; Carbon Radioisotopes; Carcinoma, Squamous Cell; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Positron-Emission Tomography; Radiopharmaceuticals

2013

Trials

28 trial(s) available for misonidazole and Carcinoma, Epidermoid

ArticleYear
Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma.
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 113

    Topics: Adenocarcinoma of Lung; Aged; Aminopyridines; Anorexia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemoradiotherapy; Fatigue; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Misonidazole; Morpholines; Nausea; Phosphoinositide-3 Kinase Inhibitors; Positron Emission Tomography Computed Tomography; Radiation-Sensitizing Agents; Radiotherapy; Tumor Hypoxia

2019
Potential of [18F]-fluoromisonidazole positron-emission tomography for radiotherapy planning in head and neck squamous cell carcinomas.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2013, Volume: 189, Issue:12

    Topics: Aged; Carcinoma, Squamous Cell; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Reproducibility of Results; Sensitivity and Specificity; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Burden

2013
Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2015
Serial [18F]-fluoromisonidazole PET during radiochemotherapy for locally advanced head and neck cancer and its correlation with outcome.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemoradiotherapy; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypoxia; Kaplan-Meier Estimate; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Treatment Outcome; Tumor Burden

2015
Robustness of quantitative hypoxia PET image analysis for predicting local tumor control.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multicenter Studies as Topic; Positron-Emission Tomography; Radiopharmaceuticals; ROC Curve; Squamous Cell Carcinoma of Head and Neck

2015
Reduction of [(18)F]fluoromisonidazole uptake after neoadjuvant chemotherapy for head and neck squamous cell carcinoma.
    Molecular imaging and biology, 2011, Volume: 13, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Lymph Nodes; Male; Middle Aged; Misonidazole; Neoadjuvant Therapy; Positron-Emission Tomography; Treatment Outcome

2011
A phase III randomized study of misonidazole plus radiation vs. radiation alone for cervix cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 70, Issue:3

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Disease-Free Survival; Double-Blind Method; Female; Humans; Misonidazole; Radiation-Sensitizing Agents; Radiotherapy Dosage; Survival Rate; Uterine Cervical Neoplasms

2004
pO(2) Polarography versus positron emission tomography ([(18)F] fluoromisonidazole, [(18)F]-2-fluoro-2'-deoxyglucose). An appraisal of radiotherapeutically relevant hypoxia.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2004, Volume: 180, Issue:10

    Topics: Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Misonidazole; Oximetry; Oxygen; Oxygen Consumption; Polarography; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity

2004
Misonidazole combined with radiotherapy in the treatment of inoperable squamous cell carcinoma of the lung. A double-blind randomized trial.
    Cancer, 1983, Jul-01, Volume: 52, Issue:1

    Topics: Aged; Carcinoma, Squamous Cell; Double-Blind Method; Esophagitis; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Placebos; Pneumonia; Radiation Injuries; Radiotherapy Dosage; Random Allocation; Vomiting

1983
A study of the effect of misonidazole in conjunction with radiotherapy for the treatment of head and neck cancer. MRC working party on misonidazole in head and neck cancer.
    The British journal of radiology, 1984, Volume: 57, Issue:679

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Radiotherapy; Radiotherapy Dosage; Random Allocation

1984
Primary tumor control after radiotherapy for carcinoma of the bronchus.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:4

    Topics: Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Double-Blind Method; Humans; Misonidazole; Neoplasm Metastasis; Nitroimidazoles; Radiation Tolerance

1984
The treatment of locally advanced head and neck cancer with misonidazole, hyperbaric oxygen and irradiation: an interim report.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation

1984
Hyperfractionated radiotherapy with or without misonidazole: results of a prospective randomized study in stage III-IV squamous cell carcinoma of the head and neck.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:10

    Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cobalt Radioisotopes; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Prospective Studies; Radiation-Sensitizing Agents; Radioisotope Teletherapy; Radiotherapy Dosage; Random Allocation

1984
Irradiation with or without misonidazole for patients with stages IIIB and IVA carcinoma of the cervix: final results of RTOG 80-05. Radiation Therapy Oncology Group.
    International journal of radiation oncology, biology, physics, 1999, Jun-01, Volume: 44, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Humans; Middle Aged; Misonidazole; Neoplasm Staging; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Failure; Uterine Cervical Neoplasms

1999
Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jan-15, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Hypoxia; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Administration Schedule; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Middle Aged; Misonidazole; Radiation-Sensitizing Agents; Radiopharmaceuticals; Survival Analysis; Tirapazamine; Tomography, Emission-Computed; Triazines

2001
Elapsed treatment days--a critical item for radiotherapy quality control review in head and neck trials: RTOG report.
    International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:1

    Topics: Carcinoma, Squamous Cell; Clinical Protocols; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Misonidazole; Outcome and Process Assessment, Health Care; Radiation-Sensitizing Agents

1991
A randomized phase III protocol for the evaluation of misonidazole combined with radiation in the treatment of patients with brain metastases (RTOG-7916).
    International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Prospective Studies; Radiation-Sensitizing Agents; Survival Analysis

1991
Radiation therapy alone or combined with misonidazole in the treatment of locally advanced non-oat cell lung cancer: report of an RTOG prospective randomized trial.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Lung Neoplasms; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prognosis; Prospective Studies; Random Allocation

1989
A phase I/II study of the hypoxic cell sensitizer misonidazole as an adjunct to high fractional dose radiotherapy in patients with unresectable squamous cell carcinoma of the head and neck: a RTOG randomized study (#79-04).
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Multicenter Studies as Topic; Prospective Studies; Radiotherapy; Radiotherapy Dosage; Random Allocation

1989
Misonidazole combined with split-course radiotherapy in the treatment of invasive carcinoma of larynx and pharynx: report from the DAHANCA 2 study.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Double-Blind Method; Female; Humans; Laryngeal Neoplasms; Male; Misonidazole; Multicenter Studies as Topic; Neoplasm Invasiveness; Pharyngeal Neoplasms; Prognosis; Random Allocation

1989
Misonidazole combined with radiotherapy in the treatment of carcinoma of the uterine cervix.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Double-Blind Method; Female; Humans; Misonidazole; Multicenter Studies as Topic; Random Allocation; Uterine Cervical Neoplasms

1989
The role of hemoglobin concentration in the outcome of misonidazole-sensitized radiotherapy of head and neck cancers: based on RTOG trial #79-15.
    International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:6

    Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Hemoglobins; Humans; Male; Misonidazole; Multicenter Studies as Topic; United States

1989
Radiotherapy with or without misonidazole for patients with stage IIIB or stage IVA squamous cell carcinoma of the uterine cervix: preliminary report of a Radiation Therapy Oncology Group randomized trial.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Humans; Middle Aged; Misonidazole; Radiotherapy; Radiotherapy, High-Energy; Random Allocation; Uterine Cervical Neoplasms

1987
A randomized trial of hydroxyurea versus misonidazole adjunct to radiation therapy in carcinoma of the cervix. A preliminary report of a Gynecologic Oncology Group study.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Hydroxyurea; Middle Aged; Misonidazole; Random Allocation; Uterine Cervical Neoplasms

1988
Failure of misonidazole-sensitized radiotherapy to impact upon outcome among stage III-IV squamous cancers of the head and neck.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:8

    Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation

1987
Effect of misonidazole dose on survival in patients with stage IIIB-IVA squamous cell carcinoma of the uterine cervix: an RTOG randomized trial.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7

    Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Misonidazole; Prognosis; Radiation-Sensitizing Agents; Random Allocation; Uterine Cervical Neoplasms

1986
Irradiation with misonidazole and hyperbaric oxygen: final report on a randomized trial in advanced head and neck cancer.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:8

    Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Misonidazole; Prospective Studies; Radiation-Sensitizing Agents; Random Allocation

1986
[Esophageal carcinoma: the final results of a multicenter and controlled German study with misonidazole and radiation].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1986, Volume: 162, Issue:11

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Esophageal Neoplasms; Esophagus; Female; Humans; Male; Middle Aged; Misonidazole; Neoplasm Staging; Prospective Studies; Radiotherapy Dosage; Random Allocation

1986

Other Studies

72 other study(ies) available for misonidazole and Carcinoma, Epidermoid

ArticleYear
Evaluation of non-Gaussian model-based diffusion-weighted imaging in oral squamous cell carcinoma: comparison with tumour functional information derived from positron-emission tomography.
    Clinical radiology, 2020, Volume: 75, Issue:5

    Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Diffusion Magnetic Resonance Imaging; Female; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals

2020
    Oral surgery, oral medicine, oral pathology and oral radiology, 2017, Volume: 124, Issue:3

    Topics: Adult; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Proliferation; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Hypoxia

2017
Residual tumour hypoxia in head-and-neck cancer patients undergoing primary radiochemotherapy, final results of a prospective trial on repeat FMISO-PET imaging.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 124, Issue:3

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prospective Studies; Squamous Cell Carcinoma of Head and Neck; Tumor Burden

2017
Hypoxic volume evaluated by
    International journal of oral and maxillofacial surgery, 2018, Volume: 47, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Neck Dissection; Neoplasm Grading; Neoplasm Recurrence, Local; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Survival Rate; Treatment Outcome; Tumor Hypoxia

2018
Optimal timing of fluorine-18-fluoromisonidazole positron emission tomography/computed tomography for assessment of tumor hypoxia in patients with head and neck squamous cell carcinoma.
    Nuclear medicine communications, 2018, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Positron Emission Tomography Computed Tomography; Time Factors; Tumor Hypoxia; Young Adult

2018
18F-fluoromisonidazole PET uptake is correlated with hypoxia-inducible factor-1α expression in oral squamous cell carcinoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:7

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic

2013
Correlation between tumor oxygenation and 18F-fluoromisonidazole PET data simulated based on microvessel images.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Computer Simulation; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Mice; Microvessels; Misonidazole; Oxygen; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Cells, Cultured

2013
Effect of [(18)F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 111, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Radiation-Sensitizing Agents; Radionuclide Imaging; Radiopharmaceuticals; Random Allocation; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays

2014
Advantage of FMISO-PET over FDG-PET for predicting histological response to preoperative chemotherapy in patients with oral squamous cell carcinoma.
    European journal of nuclear medicine and molecular imaging, 2014, Volume: 41, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Positron-Emission Tomography; Preoperative Period; Treatment Outcome

2014
Hypoxia imaging with [18F]-FMISO-PET for guided dose escalation with intensity-modulated radiotherapy in head-and-neck cancers.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015, Volume: 191, Issue:3

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Humans; Male; Middle Aged; Misonidazole; Neoplasm Staging; Otorhinolaryngologic Neoplasms; Positron-Emission Tomography; Prognosis; Radiotherapy; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Tumor Burden

2015
The end of the hypoxic EPOch.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Anemia; Blood Transfusion; Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Erythropoietin; Etanidazole; Female; Head and Neck Neoplasms; Humans; Male; Misonidazole; Radiation-Sensitizing Agents; Receptors, Erythropoietin; Treatment Failure; Uterine Cervical Neoplasms

2015
The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Heterografts; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden

2015
Feasibility of 18F-Fluoromisonidazole Kinetic Modeling in Head and Neck Cancer Using Shortened Acquisition Times.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:3

    Topics: Algorithms; Animals; Carcinoma, Squamous Cell; Cohort Studies; Colorectal Neoplasms; Head and Neck Neoplasms; HT29 Cells; Humans; Hypoxia; Image Processing, Computer-Assisted; Misonidazole; Neoplasm Transplantation; Perfusion; Radionuclide Imaging; Radiopharmaceuticals; Rats; Reproducibility of Results; Retrospective Studies; ROC Curve

2016
Imaging Hypoxia with ¹⁸F-Fluoromisonidazole: Challenges in Moving to a More Complicated Analysis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Misonidazole; Radionuclide Imaging; Radiopharmaceuticals

2016
Multiparametric [18F]Fluorodeoxyglucose/ [18F]Fluoromisonidazole Positron Emission Tomography/ Magnetic Resonance Imaging of Locally Advanced Cervical Cancer for the Non-Invasive Detection of Tumor Heterogeneity: A Pilot Study.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Middle Aged; Misonidazole; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Retrospective Studies; Tumor Burden; Uterine Cervical Neoplasms

2016
Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O2 consumption?
    Medical physics, 2016, Volume: 43, Issue:7

    Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Computer Simulation; Feasibility Studies; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Hypoxia; Mice, Nude; Misonidazole; Models, Biological; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment

2016
Automated PET Radiotracer Manufacture on the BG75 System and Imaging Validation Studies of [18F]fluoromisonidazole ([18F]FMISO).
    Current radiopharmaceuticals, 2016, Volume: 9, Issue:3

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chromatography, High Pressure Liquid; Glioblastoma; Humans; Mice; Misonidazole; Positron Emission Tomography Computed Tomography; Radiographic Image Interpretation, Computer-Assisted; Radiopharmaceuticals; Tissue Distribution

2016
Analysis of relation between hypoxia PET imaging and tissue-based biomarkers during head and neck radiochemotherapy.
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:11

    Topics: Adult; Aged; Biomarkers, Tumor; Carbonic Anhydrase IX; Carcinoma, Squamous Cell; Chemoradiotherapy; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Immunohistochemistry; Ku Autoantigen; Male; Middle Aged; Misonidazole; Papillomavirus Infections; Positron-Emission Tomography; Proportional Hazards Models; Radiopharmaceuticals; Tomography, X-Ray Computed; Tumor Hypoxia

2016
Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases.
    International journal of radiation oncology, biology, physics, 2010, Aug-01, Volume: 77, Issue:5

    Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Retrospective Studies; Statistics, Nonparametric

2010
Influence of manipulating hypoxia in solid tumors on the radiation dose-rate effect in vivo, with reference to that in the quiescent cell population.
    Japanese journal of radiology, 2010, Volume: 28, Issue:2

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Carbon Radioisotopes; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Fluorescent Antibody Technique; Gamma Rays; Mice; Mice, Inbred C3H; Misonidazole; Niacinamide; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Vitamin B Complex

2010
Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:7

    Topics: Biosensing Techniques; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Hypoxia; Microchemistry; Microelectrodes; Misonidazole; Neoplasms; Oxygen; Positron-Emission Tomography; Sarcoma; Soft Tissue Neoplasms

2010
Comparison of (immuno-)fluorescence data with serial [¹⁸F]Fmiso PET/CT imaging for assessment of chronic and acute hypoxia in head and neck cancers.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:3

    Topics: Acute Disease; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chronic Disease; Disease Progression; Head and Neck Neoplasms; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Mice; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Radiation-Sensitizing Agents; Tomography, X-Ray Computed; Transplantation, Heterologous

2011
18F-fluoromisonidazole positron emission tomography before treatment is a predictor of radiotherapy outcome and survival prognosis in patients with head and neck squamous cell carcinoma.
    Annals of nuclear medicine, 2011, Volume: 25, Issue:9

    Topics: Adult; Aged; Analysis of Variance; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome

2011
Hypoxia-targeted radiotherapy dose painting for head and neck cancer using (18)F-FMISO PET: a biological modeling study.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:8

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Cohort Studies; Fluorodeoxyglucose F18; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Models, Biological; Neoplasm Staging; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated

2013
Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models.
    Nuclear medicine communications, 2003, Volume: 24, Issue:5

    Topics: Animals; Azides; Carcinoma, Squamous Cell; CHO Cells; Cricetinae; Cricetulus; Fibrosarcoma; Fructose; Glucaric Acid; Hypoxia; Male; Metabolic Clearance Rate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Organotechnetium Compounds; Oxygen; Potassium Cyanide; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution

2003
Effect of intratumoral heterogeneity in oxygenation status on FMISO PET, autoradiography, and electrode Po2 measurements in murine tumors.
    International journal of radiation oncology, biology, physics, 2005, Jul-01, Volume: 62, Issue:3

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Oxygen Consumption; Partial Pressure; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals

2005
Animal-specific positioning molds for registration of repeat imaging studies: comparative microPET imaging of F18-labeled fluoro-deoxyglucose and fluoro-misonidazole in rodent tumors.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Equipment Design; Equipment Failure Analysis; Fluorodeoxyglucose F18; Humans; Male; Misonidazole; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Rats; Reproducibility of Results; Restraint, Physical; Sensitivity and Specificity; Species Specificity; Subtraction Technique

2006
Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Glioblastoma; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging

2006
Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Sep-15, Volume: 12, Issue:18

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorodeoxyglucose F18; Follow-Up Studies; Head and Neck Neoplasms; Humans; Middle Aged; Misonidazole; Multivariate Analysis; Positron-Emission Tomography; Survival Analysis

2006
The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography.
    International journal of oncology, 2007, Volume: 30, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coordination Complexes; Mice; Misonidazole; Neoplasm Transplantation; Organometallic Compounds; Oxygen; Positron-Emission Tomography; Thiosemicarbazones

2007
Hypoxia-imaging with (18)F-Misonidazole and PET: changes of kinetics during radiotherapy of head-and-neck cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2007, Volume: 83, Issue:3

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Kinetics; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prospective Studies; Radiation-Sensitizing Agents

2007
pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle o
    BMC cancer, 2007, Jun-28, Volume: 7

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Misonidazole; Oxygen Consumption; Polarography; Positron-Emission Tomography; Prognosis; Ultrasonography, Doppler, Color

2007
Reduced fractionation and the potential of hypoxic cell sensitizers in irradiation of malignant epithelial tumors.
    International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Misonidazole; Mouth Neoplasms; Nitroimidazoles; Oropharynx; Pharyngeal Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Retrospective Studies

1980
[Biological studies of proton irradiation under combination with a hypoxic cell sensitizer].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1982, Apr-25, Volume: 42, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Protons; Radiotherapy, High-Energy; Skin Neoplasms

1982
The use of misonidazole in association with a three-fractions per day regimen in advanced head and neck epidermoid cancer. A pilot study.
    American journal of clinical oncology, 1983, Volume: 6, Issue:1

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Erythema; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Pilot Projects; Radiotherapy Dosage

1983
Interstitial misonidazole. A preliminary report on a new perspective in clinical radiation sensitization and hypoxic cell chemotherapy.
    Cancer, 1984, Oct-15, Volume: 54, Issue:8

    Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Injections; Male; Melanoma; Middle Aged; Misonidazole; Nitroimidazoles; Skin Neoplasms

1984
The topical use of misonidazole in bladder cancer.
    Progress in clinical and biological research, 1983, Volume: 132D

    Topics: Administration, Oral; Administration, Topical; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Humans; Kinetics; Misonidazole; Mucous Membrane; Nitroimidazoles; Urinary Bladder; Urinary Bladder Neoplasms

1983
[Experimental studies on radiosensitization of hypoxic cancer cells].
    Nihon Sanka Fujinka Gakkai zasshi, 1983, Volume: 35, Issue:11

    Topics: Animals; Carcinoma, Squamous Cell; Female; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Uterine Cervical Neoplasms

1983
[Flow-microfluorometric studies on the effect of misonidazole as a radiosensitizer for human uterine cervical carcinoma transplanted to nude mice].
    Nihon Sanka Fujinka Gakkai zasshi, 1983, Volume: 35, Issue:12

    Topics: Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Flow Cytometry; Humans; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Uterine Cervical Neoplasms

1983
[Effect of even or uneven dose fractionation regime on murine squamous cell carcinoma with combined use of misonidazole].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1983, Oct-25, Volume: 43, Issue:10

    Topics: Animals; Carcinoma, Squamous Cell; Combined Modality Therapy; Fibrosarcoma; Mice; Mice, Inbred Strains; Misonidazole; Nitroimidazoles; Radiotherapy Dosage

1983
Fatal misonidazole-induced encephalopathy: an RTOG case report.
    Cancer, 1982, Feb-01, Volume: 49, Issue:3

    Topics: Brain Diseases; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Misonidazole; Nitroimidazoles; Palatal Neoplasms; Tongue Neoplasms

1982
Large fraction radiotherapy plus misonidazole for treatment of advanced lung cancer: report of a phase I/II trial.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Radiotherapy; Radiotherapy Dosage

1982
Misonidazole Neuropathy: a clinical, electrophysiological, and histological study.
    Annals of neurology, 1982, Volume: 12, Issue:1

    Topics: Aged; Carcinoma, Squamous Cell; Electromyography; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Median Nerve; Middle Aged; Misonidazole; Nerve Fibers, Myelinated; Nervous System Diseases; Neural Conduction; Neuromuscular Diseases; Nitroimidazoles; Paresthesia; Peroneal Nerve; Pharyngeal Neoplasms; Sensation; Sural Nerve; Tibial Nerve

1982
The feasibility of high-dose multiple daily fractionation and its combination with anoxic cell sensitizers in the treatment of head and neck cancer. A pilot study of the Radiotherapy Group of the EORTC (European Organisation for Research on Treatment of C
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:10

    Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Pilot Projects; Prognosis; Radiotherapy Dosage

1982
Effects of misonidazole on tumor cell radiation sensitivity and potentially lethal damage repair in vivo and in vitro.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Time Factors

1981
Pilot study of radiotherapy with misonidazole in head and neck cancer.
    Clinical radiology, 1981, Volume: 32, Issue:2

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Pilot Projects; Radiotherapy Dosage

1981
Comparison of hyperbaric oxygen and misonidazole in fractionated irradiation of murine tumors.
    Radiation research, 1981, Volume: 87, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Female; Hyperbaric Oxygenation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Skin

1981
Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients.
    British journal of cancer, 1981, Volume: 44, Issue:4

    Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Half-Life; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Nitroimidazoles; Phenytoin; Time Factors

1981
The value of adjuvant misonidazole in the definitive irradiation of advanced head and neck squamous cancer: an RTOG pilot study (#78-02).
    International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:12

    Topics: Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Mouth Neoplasms; Nausea; Neoplasm Recurrence, Local; Neoplasm Staging; Nitroimidazoles; Paresthesia; Pharyngeal Neoplasms; Prognosis

1981
Use of the comet assay to detect hypoxic cells in murine tumours and normal tissues exposed to bioreductive drugs.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:3

    Topics: Aerobiosis; Animals; Antineoplastic Agents; Bone Marrow; Carcinoma, Squamous Cell; Cell Hypoxia; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Electrophoresis, Agar Gel; Hydrogen-Ion Concentration; Male; Mice; Mice, Inbred C3H; Misonidazole; Organ Specificity; Oxidation-Reduction; Radiation-Sensitizing Agents; Spleen; Tirapazamine; Triazines

1995
Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. II. RSU 1069.
    British journal of cancer, 1995, Volume: 71, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Damage; DNA Repair; DNA, Neoplasm; Fibroblasts; Flow Cytometry; Kinetics; Male; Mice; Mice, Inbred C3H; Misonidazole

1995
[Radiosensitizing effects of nitroimidazole derivative, KIN-804].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1995, Volume: 55, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Hydroxamic Acids; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Skin Neoplasms

1995
Radiosensitizing activity and pharmacokinetics of multiple dose administered KU-2285 in peripheral nerve tissue in mice.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Etanidazole; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Peripheral Nerves; Radiation-Sensitizing Agents

1994
In vivo radiosensitizing effect of nitroimidazole derivative KIN-804.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Hydroxamic Acids; Lethal Dose 50; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents

1994
The influence of irradiation of the tumor bed on tumor hypoxia: measurements by radiation response, oxygen electrodes, and nitroimidazole binding.
    Radiation research, 1993, Volume: 135, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen; Partial Pressure; Sarcoma; Tumor Cells, Cultured

1993
Evaluation of the radiosensitizing effects of RK28 intravenous, intraarterial, and intratumoral injections on the rabbit VX2 tumor system.
    International journal of radiation oncology, biology, physics, 1996, Dec-01, Volume: 36, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Injections, Intra-Arterial; Injections, Intravenous; Male; Misonidazole; Neoplasms, Experimental; Rabbits; Radiation-Sensitizing Agents

1996
The radiosensitizing effects of hypoxic cell sensitizer on SCCVII tumors in mice evaluated by highly accurate colony formation assay assisted by microcomputer.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1996, Volume: 56, Issue:14

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Etanidazole; Male; Mice; Mice, Inbred C3H; Microcomputers; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
A comparison of the physiological effects of RSU1069 and RB6145 in the SCCVII murine tumour.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C3H; Misonidazole; Neovascularization, Pathologic; Nitroimidazoles; Oxygen; Phosphorus Radioisotopes

1996
Effect of nitroimidazole sensitizers on in vitro glycolytic metabolism of hypoxic squamous cell carcinoma.
    Acta oncologica (Stockholm, Sweden), 2000, Volume: 39, Issue:2

    Topics: Carcinoma, Squamous Cell; Cell Death; Cell Hypoxia; Fluorodeoxyglucose F18; Humans; Misonidazole; Nimorazole; Radiation-Sensitizing Agents; Tomography, Emission-Computed; Tritium; Tumor Cells, Cultured

2000
The penetration of misonidazole into spontaneous canine tumours.
    British journal of cancer, 1979, Volume: 40, Issue:2

    Topics: Adenocarcinoma; Anesthesia, Intravenous; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Dog Diseases; Dogs; Female; Fibrosarcoma; Half-Life; Lymphoma, Non-Hodgkin; Male; Mammary Glands, Animal; Meningioma; Misonidazole; Neoplasms; Nitroimidazoles; Osteosarcoma; Pentobarbital

1979
Hydralazine does not increase hypoxia in tumors growing in preirradiated tissue.
    International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:6

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Squamous Cell; Cell Hypoxia; Drug Administration Schedule; Female; Hydralazine; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Radiotherapy Dosage

1991
Palliative topical and systemic misonidazole with low-dose irradiation for recurrent carcinoma of the cervix uteri.
    Cancer, 1986, Sep-01, Volume: 58, Issue:5

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Misonidazole; Neoplasm Recurrence, Local; Palliative Care; Radiotherapy Dosage; Uterine Cervical Neoplasms

1986
Distribution, oxygenation, and clonogenicity of macrophages in a murine tumor.
    Cancer communications, 1989, Volume: 1, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Survival; DNA Replication; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Macrophages; Mice; Mice, Inbred C3H; Misonidazole; Reference Values; Thymidine; Tritium

1989
Misonidazole binding in SCCVII tumors in relation to the tumor blood supply.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Separation; Flow Cytometry; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen

1989
Oxic and hypoxic cells in a murine squamous cell carcinoma.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Constriction; Dose-Response Relationship, Radiation; Female; Hypoxia; Idoxuridine; Iodine Radioisotopes; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Oxygen Consumption; Skin Neoplasms

1988
Therapeutic gain factors for fractionated radiation treatment of spontaneous murine tumors using fast neutrons, photons plus O2(1) or 3 ATA, or photons plus misonidazole.
    Radiation research, 1988, Volume: 116, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Combined Modality Therapy; Fast Neutrons; Female; Fibrosarcoma; Hyperbaric Oxygenation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Oxygen; Radiotherapy Dosage

1988
Interstitial misonidazole: clinical experience in advanced mouth cancer.
    Clinical radiology, 1988, Volume: 39, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Drug Implants; Humans; Misonidazole; Mouth Neoplasms; Needles; Neoplasm Recurrence, Local; Swine

1988
Prognostic factors influencing survival in combined radiotherapy and surgery of squamous cell carcinoma of the esophagus with special reference to a histopathologic grading system.
    Cancer, 1988, Sep-01, Volume: 62, Issue:5

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Esophageal Neoplasms; Humans; Misonidazole; Prognosis; Time Factors

1988
[Enhancement of radiation response of SqII mouse tumors by combined treatment with misonidazole, vidarabine, and ACNU].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1987, Jan-25, Volume: 47, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Male; Mice; Misonidazole; Nimustine; Nitrosourea Compounds; Vidarabine

1987
Primary radiotherapy of larynx and pharynx carcinoma--an analysis of some factors influencing local control and survival.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:4

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Hemoglobins; Humans; Laryngeal Neoplasms; Male; Misonidazole; Pharyngeal Neoplasms; Prognosis

1986
Response of human tumour xenografts to fractionated X-irradiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1986, Volume: 6, Issue:1

    Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Humans; Male; Mice; Mice, Nude; Misonidazole; Mouth Neoplasms; Neoplasm Transplantation; Photochemotherapy; Radiotherapy Dosage; Tonsillar Neoplasms; Transplantation, Heterologous

1986
A comparison of the tumour concentrations obtainable with misonidazole and Ro 03-8799.
    The British journal of radiology, 1986, Volume: 59, Issue:705

    Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cricetinae; Cricetulus; Female; Humans; Male; Melanoma; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

1986