Page last updated: 2024-08-22

misonidazole and Anoxemia

misonidazole has been researched along with Anoxemia in 141 studies

Research

Studies (141)

Timeframe	Studies, this research(%)	All Research%
pre-1990	61 (43.26)	18.7374
1990's	13 (9.22)	18.2507
2000's	14 (9.93)	29.6817
2010's	41 (29.08)	24.3611
2020's	12 (8.51)	2.80

Authors

Authors	Studies
Chan, YW; Cyr, JE; Linder, KE; Malley, MF; Nowotnik, DP; Nunn, AD	1
Angermeier, A; Della Manna, D; Larimer, BM; Li, Y; Reeves, KM; Song, PN; Sorace, AG; Wang, J; Yang, ES	1
Baltas, D; Fennell, JT; Grosu, AL; Mix, M; Nicolay, NH; Ruf, J; Rühle, A; Stoian, R; Thomsen, AR; Vaupel, P; Wiedenmann, N	1
Alber, M; Belka, C; La Fougère, C; Nikolaou, K; Paulsen, F; Pfannenberg, C; Reimold, M; Reischl, G; Thorwarth, D; Welz, S; Zips, D	1
Barbier, EL; Bernaudin, M; Chakhoyan, A; Chazalviel, L; Corroyer-Dulmont, A; Divoux, D; Guillouet, S; Toutain, J; Touzani, O; Valable, S	1
Bourigault, P; Higgins, GS; Macpherson, RE; McGowan, DR; Skwarski, M	1
Boeke, S; Bowden, G; Cotton, J; Krueger, MA; Leibfarth, S; Pichler, BJ; Thorwarth, D; Winter, RM; Zips, D	1
Furuya, S; Hirata, K; Kobayashi, H; Kobayashi, K; Kudo, K; Kuge, Y; Magota, K; Manabe, O; Shiga, T; Tamaki, N; Terasaka, S; Toyonaga, T; Yamaguchi, S	1
Baell, JB; Davis, TP; Davydova, M; Goos, JACM; Greguric, I; Lengkeek, N; Lewis, JS; Quinn, JF; Whittaker, MR	1
Baumann, M; Boeke, S; Gregoire, V; Hofheinz, F; Johansen, J; Krause, M; Löck, S; Mönnich, D; Overgaard, J; Saksø Mortensen, L; Saksø, M; Seidlitz, A; Skripcak, T; Troost, EGC; Zips, D; Zöphel, K; Zschaeck, S	1
Arnberg, F; Holmin, S; Ingemann Jensen, A; Jussing, E; Little, PV; Lu, L; Mitsios, N; Mulder, J; Tran, TA	1
Christophi, C; Fang, C; Gan, H; Lee, ST; Liu, Z; Muralidharan, V; Pathmaraj, K; Sachinidis, J; Scott, AM; Tebbutt, N; Wong, P	1
Andreev, DN; Bellaye, PS; Bonniaud, P; Bouchard, A; Cochet, A; Collin, B; Frenay, J; Goirand, F; Guillemin, M; Helbling, A; Kucheryavy, YA; Mayev, IV; Moreau, M; Mothes, C; Oudot, A; Tanguy, J	1
Grimes, DR; Warren, DR; Warren, S	1
Huang, Y; Li, L; Liu, W; Lu, H; Wei, Y; Yu, J; Yu, Q; Yuan, S; Zhao, S; Zheng, J	1
Dong, M; Guo, S; Han, X; Li, G; Li, H; Lin, Y; Mi, Y; Ruan, Q; Wang, B; Xu, D; Zhang, X	1
Shimizu, Y	1
Carson, RE; Chan, C; Fung, EK; Jin, X; Liu, C; Mulnix, T; Naganawa, M	1
Badimon, JJ; Fayad, ZA; Fuster, V; Izquierdo-Garcia, D; Mateo, J	1
Fatema, CN; Kitagawa, Y; Kuge, Y; Nishijima, K; Tamaki, N; Yasuda, K; Yu, W; Zhao, S; Zhao, Y	1
Hawkins-Daarud, AJ; Hendrickson, K; Jacobs, J; Kinahan, P; Krohn, KA; Mrugala, MM; Neal, ML; Rockhill, JK; Rockne, RC; Swanson, KR; Trister, AD	1
Banerjee, S; Mallia, MB; Mathur, A; Sarma, HD	1
Akula, MR; Bois, F; Carlson, DJ; Collier, L; Hammond, K; Huang, Y; Kabalka, GW; Kelada, OJ; Ropchan, J; Zheng, MQ	1
Bezak, E; Jennings, M; Marcu, LG	1
Fink, JR; Krohn, KA; Mankoff, DA; McLaughlin, LJ; Muzi, JP; Muzi, M; O'Sullivan, JN; Peterson, LM; Rajendran, JG	1
Mönnich, D; Thorwarth, D; Troost, EG; van Elmpt, W; Wack, LJ; Zegers, CM; Zips, D	1
Cui, YL; Li, XF; Wang, X	1
Hamaji, M; Harada, H; Kimura, H; Koizumi, K; Koyasu, S; Nakamoto, Y; Nobashi, T; Sano, K; Togashi, K; Tsuji, Y	1
Abolmaali, N; Appold, S; Baumann, M; Gudziol, V; Haase, R; Kotzerke, J; Krause, M; Perrin, R; Richter, C; Steinbach, J; Stützer, K; Zips, D; Zöphel, K; Zschaeck, S	1
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Mix, M; Nestle, U; Pfeiffer, J; Vach, W; Weber, WA; Wiedenmann, NE	1
la Fougère, C; Mauz, PS; Mönnich, D; Nikolaou, K; Pfannenberg, C; Reischl, G; Thorwarth, D; Welz, S; Zips, D	1
Higashino, K; Kuge, Y; Masaki, Y; Nishijima, K; Numata, Y; Sakamoto, S; Shimizu, Y; Tamaki, N; Tanaka, Y; Yamaguchi, Y; Yoshioka, T; Zhao, S	1
Carlin, SD; Gönen, M; Grkovski, M; Humm, JL; Lee, NY; Nehmeh, SA; Schöder, H; Schwartz, J; Zanzonico, PB	1
Yoshimoto, M	1
Aigbirhio, FI; Carter, EL; Coles, JP; Fryer, TD; Gee, GS; Geeraerts, T; Grossac, J; Hong, YT; Lupson, V; Menon, DK; Newcombe, VF; Outtrim, J; Smith, R; Veenith, TV	1
Hu, X; Huang, Y; Wang, S; Wei, Y; Yu, J; Yu, Q; Yuan, S; Zhao, S; Zhao, W; Zhu, S	1
Baumann, M; Mönnich, D; Thorwarth, D; Wack, LJ; Yaromina, A; Zips, D	1
Anzellotti, AI; Frank, JE; Hillesheim, DA; Khachaturian, MH; Merrill, JR; Yuan, H	1
Partridge, M; Warren, DR	1
Cheguillaume, A; De Bast, M; de Groot, T; Gillart, J; Grégoire, V; Haustermans, K; Labar, D; Mahy, P	1
Bol, A; Bormans, G; Cloetens, L; Dubois, L; Grégoire, V; Haustermans, K; Labar, D; Landuyt, W; Mortelmans, L; Nuyts, J	1
Adamsen, TC; Chakraborty, G; Harpold, HL; Krohn, KA; Muzi, M; Rockne, R; Spence, AM; Swanson, KR; Wang, CH	1
Ametamey, S; Dominietto, M; Honer, M; Keist, R; Kotevic, I; Lehmann, S; Rudin, M; Stiehl, DP; Wenger, RH; Wollenick, K	1
Georgi, JC; Guillem, J; Humm, JL; Lee, NY; Narayanan, M; Schöder, H; Wang, W	1
Bentzen, L; Buus, S; Keiding, S; Mortensen, LS; Munk, OL; Nordsmark, M; Overgaard, J	1
Donnan, GA; Howells, DW; McLeod, DD; Spratt, NJ	1
Chitneni, SK; Dewhirst, MW; Palmer, GM; Zalutsky, MR	1
Alber, M; Kaanders, JH; Mönnich, D; Oyen, WJ; Thorwarth, D; Troost, EG	2
Alessio, AM; Alvord, EC; Anderson, AR; Chakraborty, G; Champley, K; Claridge, J; Gu, S; Kinahan, PE; Krohn, KA; Muzi, M; Rockne, R; Spence, AM; Swanson, KR	1
Blower, PJ; Handley, MG; Medina, RA; Nagel, E; Southworth, R	1
Allen, PD; Cornelissen, B; Dilworth, JR; Falzone, N; Gouverneur, V; Hill, SA; Hueting, R; Hussien, K; Kersemans, V; Muschel, RJ; Smart, SC; Tredwell, M	1
Aga, F; Kawai, N; Kudomi, N; Maeda, Y; Nishiyama, Y; Ono, Y; Yamamoto, Y	1
Chowdhury, NF; Kuge, Y; Murakami, M; Nishijima, K; Takiguchi, M; Tamaki, N; Yu, W; Zhao, S; Zhao, Y	1
Askoxylakis, V; Bischof, M; Debus, J; Dimitrakopoulou-Strauss, A; Dinkel, J; Eichinger, M; Haberkorn, U; Huber, PE; Kopp-Schneider, A; Sommer, G; Stieltjes, B; Strauss, LG; Thieke, C	1
Ito, YM; Kasai, K; Kuge, Y; Magota, K; Okamoto, S; Shiga, T; Shirato, H; Tamaki, N; Yasuda, K	1
Dallaudiere, B; Hess, A; Hummel, V; Lincot, J; Maubon, A; Monteil, J; Preux, PM	1
Barré, L; Bernaudin, M; Corroyer-Dulmont, A; Divoux, D; Durand, L; MacKenzie, ET; Marteau, L; Pérès, EA; Petit, E; Roussel, S; Toutain, J; Valable, S	1
Ballinger, JR; Hsue, V; Rauth, AM	1
Bolton, DM; Davis, ID; Foo, SS; Lawrentschuk, N; Murone, C; Poon, AM; Putra, LG; Scott, AM	1
Alber, M; Eschmann, SM; Paulsen, F; Scheiderbauer, J; Thorwarth, D	1
Buell, U; Coenen, HH; DiMartino, E; Eble, M; Gagel, B; Hamacher, K; Reinartz, P; Westhofen, M; Zimny, M	1
Chang, CW; Chen, CH; Chou, TK; Lin, WJ; Liu, RS; Wang, HE; Wang, SJ	1
Brader, P; Fong, Y; Hricak, H; Humm, JL; Ling, CC; Reid, V; Riedl, CC; Wen, B; Woo, Y; Zanzonico, P	1
Smith, BR	1
Gutin, PH; Phillips, TL; Wara, WM; Wilson, CB	1
Brustad, T; Pettersen, EO; Rofstad, EK	1
Chapman, JD	1
Petin, VG	1
Okajima, S; Okumura, Y	1
Adams, GE	1
Maezawa, H; Mori, T; Murayama, C; Ohizumi, Y	1
Asao, T; Fujita, E; Mori, T; Murayama, C; Nagao, Y; Suzue, T; Takao, S	1
Kogelnik, HD	1
Brown, JM; Bump, EA; Taylor, YC	1
Grdina, DJ; Mian, TA; Theiss, JC	1
Born, JL; Garcia, DJ; Smith, BR	1
Josephy, PD; Palcic, B; Skarsgard, LD	1
Goldman, P; Koch, RL; Rich, TA; Rose, C	1
Brown, JM; Bump, EA; Yu, NY	1
Adams, GE; Horsman, MR; Kandaiya, S; Rajaratnam, S; Smith, E; Stratford, IJ; Williamson, C	1
Hori, H; Inayama, S; Mori, T; Shibata, C	1
Korbelik, M; Palcic, B; Skarsgard, LD	1
Epp, ER; Ling, CC; Michaels, HB; Peterson, EC	1
Fielden, EM; Jenkins, TC; Millar, BC	1
Feinendegen, LE; Gewehr, K; Mühlensiepen, H; Porschen, W	1
Denekamp, J	1
Allalunis, MJ; Meeker, BE; Pedersen, JE; Turner, AR; Urtasun, RC	1
Casciari, JJ; Graham, MM; Rasey, JS	1
Baumgardner, KR; Born, JL; Osborne, JW; Walton, RE	1
MacPhail, S; Skov, KA	1
Berridge, MS; Lim, JL	1
Hill, RP; Hu, Q; Kavanagh, MC; Sun, A	1
Allalunis-Turner, MJ; Franko, AJ; Mercer, JR; Mielke, BW; Parliament, MB; Santos, CL; Wolokoff, BG	1
Olive, PL; Zheng, H	1
Allalunis-Turner, MJ; Franko, AJ; Parliament, MB; Wolokoff, BG	1
Bentzen, L; Falborg, L; Hansen, SB; Horsman, MR; Keiding, S; Overgaard, J	1
Born, J; Catron, T; Mendiola, MA; Smith, SM; Walker, MK	1
Donnan, GA; Hirano, T; Kazui, S; Markus, R; O'Keefe, GJ; Read, S; Reutens, DC; Sachinidis, JI; Scott, AM; Tochon-Danguy, HJ	1
Airley, R; Cowen, RL; Honess, D; Jaffar, M; Patterson, AV; Saunders, M; Stratford, IJ; Telfer, BA; van der Kogel, AJ; Williams, KJ; Wolf, CR	1
Karim, AB	1
Hall, EJ; Roizin-Towle, L	1
Deys, BF; Stap, J	1
Flockhart, IR; Sheldon, PW; Stratford, IJ; Watts, ME	1
Fowler, JF	2
Field, SB; Hornsey, S	1
Overgaard, J	1
de Langen-Omri, F; Guichard, M; Malaise, EP	1
Palcic, B; Skarsgard, LD; Skov, KA	1
Bareham, B; Eddy, HA; Reich, K; Sutherland, RM; Vanantwerp, D	1
Gulyas, S; Whitmore, GF; Wong, TW	1
Li, AP; Yuhas, JM	1
Dence, CS; Hotchkiss, RS; Hwang, DR; Karl, IE; Rust, RS; Song, SK; Wasserman, TH; Welch, MJ	1
Biskupiak, JE; Grierson, JR; Krohn, KA; Martin, GV; Rasey, JS	1
Abe, M; Hori, H; Inayama, S; Nagasawa, H; Sasai, K; Shibamoto, Y; Shibata, T; Takahashi, M; Zhou, L	1
Caldwell, JH; Cerqueira, MD; Embree, L; Krohn, KA; Martin, GV; Rasey, JS	1
Agrawal, KC; McNamara, DB; Shalinsky, DR	1
Caldwell, JH; Cerqueira, M; Grunbaum, Z; Krohn, KA; Martin, GV; Rasey, JS	1
Bergmann, SR; Dence, CS; Hwang, DR; Shelton, ME; Welch, MJ	1
Hlatky, L; Ring, CS; Sachs, RK	1
Franko, AJ; Raleigh, JA; Soderlind, KJ; Sutherland, RG	1
Adams, GE; Stratford, IJ	1
Astor, MB; Biaglow, JE; Clark, EP; Epp, ER; Hall, EJ; Roizen-Towle, L; Varnes, ME	1
Inch, WR; Jacobson, EA; Tustanoff, ER	1
Dischino, DD; Jerabek, PA; Kilbourn, MR; Patrick, TB; Welch, MJ	1
Okada, S; Sakamoto, K; Takai, Y	1
Hirst, DG; Wood, PJ	1
Miyamoto, Y; Mori, T; Murayama, C; Sakaguchi, M; Tanaka, N	1
Salwińska, E; Suwiński, J; Watras, J; Wideł, M	1
Durand, RE; Grunbaum, Z; Krohn, KA; Magee, S; Nelson, NJ; Olive, PL; Rasey, JS	1
Franko, AJ; Garrecht, BM; Hughes, D; Koch, CJ; Sharplin, J	1
Adams, GE; O'Neill, P; Sheldon, PW; Silver, AR; Stratford, IJ; Walling, JM	1
Freauff, SJ; Grunbaum, Z; Krohn, KA; Magee, S; Rasey, JS; Wilbur, DS	1
Ahmed, I; Chibber, R; Lee, B; O'Neill, P; Sheldon, PW; Stratford, IJ	1
Mulcahy, RT; Siemann, DW	1
Hattori, T; Hori, H; Igarashi, T; Inayama, S; Kitagawa, H; Noguchi, K; Satoh, T; Shibata, T; Ueno, K	1
Denekamp, J; Shrieve, DC	1
Brown, JM; Bump, EA	1
Franko, AJ	1

Reviews

11 review(s) available for misonidazole and Anoxemia

Article	Year
Individual patient data meta-analysis of FMISO and FAZA hypoxia PET scans from head and neck cancer patients undergoing definitive radio-chemotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 149 Topics: Cell Hypoxia; Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Multicenter Studies as Topic; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals	2020
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2021, Volume: 121, Issue:1 Topics: Abdominal Pain; Animals; Biomarkers; Disease Progression; Dyspepsia; Fluorodeoxyglucose F18; Humans; Hypoxia; Idiopathic Pulmonary Fibrosis; Mice; Misonidazole; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Prevalence; Radiopharmaceuticals; Sleep Wake Disorders	2021
Hypoxia imaging and radiotherapy: bridging the resolution gap. The British journal of radiology, 2017, Volume: 90, Issue:1076 Topics: Cell Hypoxia; Humans; Hypoxia; Misonidazole; Neoplasms; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiotherapy Dosage	2017
[Accumulation Mechanism of 2-Nitroimidazole-based Hypoxia Imaging Probes Revealed by Imaging Mass Spectrometry]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:11 Topics: Animals; Glutathione; Glutathione Transferase; Humans; Hypoxia; Mass Spectrometry; Mice; Misonidazole; Molecular Imaging; Molecular Probes; Multidrug Resistance-Associated Proteins; Neoplasms; Nitroimidazoles; Positron-Emission Tomography	2018
PET-specific parameters and radiotracers in theoretical tumour modelling. Computational and mathematical methods in medicine, 2015, Volume: 2015 Topics: Cell Proliferation; Coordination Complexes; Dideoxynucleosides; Diffusion; Fluorodeoxyglucose F18; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glucose; Humans; Hydrogen-Ion Concentration; Hypoxia; Misonidazole; Models, Theoretical; Multimodal Imaging; Neoplasms; Neovascularization, Pathologic; Organometallic Compounds; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Thiosemicarbazones; Tomography, X-Ray Computed	2015
[Current Status and Prospects on PET Radiopharmaceuticals for Radiotherapy]. Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2015, Volume: 35, Issue:1 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Coordination Complexes; Fluorine Radioisotopes; Humans; Hypoxia; Misonidazole; Neoplasms; Nitroimidazoles; Organometallic Compounds; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Thiosemicarbazones	2015
Molecular imaging of hypoxia. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:2 Topics: Humans; Hypoxia; Misonidazole; Neoplasms; Neovascularization, Pathologic; Nitroimidazoles; Positron-Emission Tomography; Radiography; Radiopharmaceuticals	2011
PET imaging of cardiac hypoxia: opportunities and challenges. Journal of molecular and cellular cardiology, 2011, Volume: 51, Issue:5 Topics: Acidosis; Animals; Copper; Copper Radioisotopes; Coronary Artery Disease; Coronary Circulation; Humans; Hypoxia; Misonidazole; Myocardial Ischemia; Myocardium; Oxygen; Positron-Emission Tomography; Radiation-Sensitizing Agents; Rats; Reducing Agents; Sensitivity and Specificity; Thiosemicarbazones; Tissue Distribution	2011
Hypoxia-mediated nitro-heterocyclic drugs in the radio- and chemotherapy of cancer. An overview. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Alkylating Agents; Animals; Cell Survival; Drug Synergism; Etanidazole; Hypoxia; Misonidazole; Neoplasms, Experimental; Nitrofurans; Nitrofurazone; Nitroimidazoles; Oxidation-Reduction; Radiation-Sensitizing Agents; Structure-Activity Relationship	1986
Biochemistry of reduction of nitro heterocycles. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Animals; Buthionine Sulfoximine; Catalase; Cell Division; Cell Survival; Etanidazole; Free Radicals; Glucose; Glutathione; Glycolysis; Hexosephosphates; Humans; Hypoxia; Methionine Sulfoximine; Microbodies; Microsomes; Misonidazole; Mitochondria; Nitroimidazoles; Oxidation-Reduction; Pentoses; Peroxidases; Sulfhydryl Compounds	1986
Eighth annual Juan del Regato lecture. Chemical modifiers of radiosensitivity--theory and reality: a review. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:4 Topics: Dose-Response Relationship, Radiation; Humans; Hyperbaric Oxygenation; Hypoxia; Misonidazole; Neoplasms; Radiation Tolerance; Radiation-Protective Agents; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Vasoconstriction	1985

Trials

8 trial(s) available for misonidazole and Anoxemia

Article	Year
Interleukin-6 as surrogate marker for imaging-based hypoxia dynamics in patients with head-and-neck cancers undergoing definitive chemoradiation-results from a prospective pilot trial. European journal of nuclear medicine and molecular imaging, 2022, Volume: 49, Issue:5 Topics: Biomarkers; Cell Hypoxia; Head and Neck Neoplasms; Humans; Hypoxia; Interleukin-6; Misonidazole; Pilot Projects; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck	2022
Dose escalation to hypoxic subvolumes in head and neck cancer: A randomized phase II study using dynamic [ Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 171 Topics: Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals	2022
Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure. Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9 Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed	2015
Serial [18F]-fluoromisonidazole PET during radiochemotherapy for locally advanced head and neck cancer and its correlation with outcome. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemoradiotherapy; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypoxia; Kaplan-Meier Estimate; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Treatment Outcome; Tumor Burden	2015
Robustness of quantitative hypoxia PET image analysis for predicting local tumor control. Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9 Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multicenter Studies as Topic; Positron-Emission Tomography; Radiopharmaceuticals; ROC Curve; Squamous Cell Carcinoma of Head and Neck	2015
A Comparative Study of Noninvasive Hypoxia Imaging with 18F-Fluoroerythronitroimidazole and 18F-Fluoromisonidazole PET/CT in Patients with Lung Cancer. PloS one, 2016, Volume: 11, Issue:6 Topics: Adult; Aged; Demography; Female; Humans; Hypoxia; Lung Neoplasms; Male; Middle Aged; Misonidazole; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Tissue Distribution	2016
Multimodal hypoxia imaging and intensity modulated radiation therapy for unresectable non-small-cell lung cancer: the HIL trial. Radiation oncology (London, England), 2012, Sep-14, Volume: 7 Topics: Algorithms; Carcinoma, Non-Small-Cell Lung; Humans; Hypoxia; Lung Neoplasms; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Salvage Therapy; Tomography, X-Ray Computed; Treatment Outcome	2012
Hypoxic cell radiosensitizers. Strahlentherapie. Sonderbande, 1978, Volume: 75 Topics: Animals; Clinical Trials as Topic; Humans; Hyperbaric Oxygenation; Hypoxia; Metronidazole; Mice; Misonidazole; Neoplasms; Radiation-Sensitizing Agents	1978

Other Studies

122 other study(ies) available for misonidazole and Anoxemia

Article	Year
TcO(PnA.O-1-(2-nitroimidazole)) [BMS-181321], a new technetium-containing nitroimidazole complex for imaging hypoxia: synthesis, characterization, and xanthine oxidase-catalyzed reduction. Journal of medicinal chemistry, 1994, Jan-07, Volume: 37, Issue:1 Topics: Chromatography, High Pressure Liquid; Crystallization; Crystallography, X-Ray; Dimethylformamide; Electrochemistry; Hypoxia; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Nitroimidazoles; Organotechnetium Compounds; Radionuclide Imaging; Stereoisomerism; Xanthine Oxidase	1994
Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 01-15, Volume: 28, Issue:2 Topics: Cell Hypoxia; CTLA-4 Antigen; Humans; Hypoxia; Misonidazole; Neoplasms; Nitroimidazoles; Phosphoramide Mustards; Positron-Emission Tomography; Programmed Cell Death 1 Receptor; Tumor Microenvironment	2022
Magnetic resonance imaging of hypoxia in acute stroke compared with fluorine-18 fluoromisonidazole-positron emission tomography: A cross-validation study? NMR in biomedicine, 2023, Volume: 36, Issue:3 Topics: Animals; Hypoxia; Ischemic Stroke; Magnetic Resonance Imaging; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Stroke	2023
Timing of hypoxia PET/CT imaging after 18F-fluoromisonidazole injection in non-small cell lung cancer patients. Scientific reports, 2022, 12-16, Volume: 12, Issue:1 Topics: Atovaquone; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Humans; Hypoxia; Lung Neoplasms; Misonidazole; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals	2022
Machine learning identifies multi-parametric functional PET/MR imaging cluster to predict radiation resistance in preclinical head and neck cancer models. European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:10 Topics: Animals; Diffusion Magnetic Resonance Imaging; Head and Neck Neoplasms; Humans; Hypoxia; Magnetic Resonance Imaging; Mice; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals	2023
Influence of the scan time point when assessing hypoxia in European journal of nuclear medicine and molecular imaging, 2020, Volume: 47, Issue:8 Topics: Glioblastoma; Humans; Hypoxia; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals	2020
pH-Responsive Polymers for Improving the Signal-to-Noise Ratio of Hypoxia PET Imaging with [ Macromolecular rapid communications, 2020, Volume: 41, Issue:11 Topics: Fluorine Radioisotopes; Humans; Hydrogen-Ion Concentration; Hypoxia; Misonidazole; Molecular Structure; Positron-Emission Tomography; Signal-To-Noise Ratio	2020
The cellular basis of increased PET hypoxia tracer uptake in focal cerebral ischemia with comparison between [ Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021, Volume: 41, Issue:3 Topics: Animals; Astrocytes; Autoradiography; Brain; Brain Ischemia; Cerebellar Cortex; Coordination Complexes; Copper Radioisotopes; Disease Models, Animal; Fluorine Radioisotopes; Hypoxia; Male; Misonidazole; Neurons; Organometallic Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Thiosemicarbazones	2021
Prevalence of hypoxia and correlation with glycolytic metabolism and angiogenic biomarkers in metastatic colorectal carcinoma. European journal of nuclear medicine and molecular imaging, 2021, Volume: 48, Issue:5 Topics: Biomarkers; Colorectal Neoplasms; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Positron-Emission Tomography; Prevalence; Radiopharmaceuticals	2021
To Explore a Representative Hypoxic Parameter to Predict the Treatment Response and Prognosis Obtained by [ Molecular imaging and biology, 2018, Volume: 20, Issue:6 Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Female; Humans; Hypoxia; Kaplan-Meier Estimate; Logistic Models; Lung Neoplasms; Male; Middle Aged; Misonidazole; Progression-Free Survival; Proportional Hazards Models; Treatment Outcome	2018
Dosimetry study of Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018, Volume: 20, Issue:10 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Humans; Hypoxia; Lung Neoplasms; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron Emission Tomography Computed Tomography; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated	2018
Event-by-event respiratory motion correction for PET with 3D internal-1D external motion correlation. Medical physics, 2013, Volume: 40, Issue:11 Topics: Carcinoma, Non-Small-Cell Lung; Fluorine Radioisotopes; Healthy Volunteers; Humans; Hypoxia; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Insulin-Secreting Cells; Kidney; Lung Neoplasms; Misonidazole; Movement; Pancreas; Positron-Emission Tomography; Regression Analysis; Reproducibility of Results; Respiration; Signal Processing, Computer-Assisted; Tetrabenazine; X-Ray Microtomography	2013
Noninvasive assessment of hypoxia in rabbit advanced atherosclerosis using ¹⁸F-fluoromisonidazole positron emission tomographic imaging. Circulation. Cardiovascular imaging, 2014, Volume: 7, Issue:2 Topics: Animals; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Disease Models, Animal; Disease Progression; Fluorine Radioisotopes; Hypoxia; Male; Misonidazole; Positron-Emission Tomography; Rabbits; Radiation-Sensitizing Agents; Reproducibility of Results; Severity of Illness Index	2014
Dual tracer evaluation of dynamic changes in intratumoral hypoxic and proliferative states after radiotherapy of human head and neck cancer xenografts using radiolabeled FMISO and FLT. BMC cancer, 2014, Sep-22, Volume: 14 Topics: Animals; Cell Proliferation; Disease Models, Animal; Head and Neck Neoplasms; Heterografts; Humans; Hypoxia; Male; Mice; Misonidazole; Radionuclide Imaging; Radiopharmaceuticals; Tumor Burden	2014
A patient-specific computational model of hypoxia-modulated radiation resistance in glioblastoma using 18F-FMISO-PET. Journal of the Royal Society, Interface, 2015, Feb-06, Volume: 12, Issue:103 Topics: Aged; Brain Neoplasms; Glioma; Humans; Hypoxia; Male; Misonidazole; Models, Biological; Positron-Emission Tomography; Precision Medicine; Radiation-Sensitizing Agents; Radiography	2015
A (99m)Tc-labeled misonidazole analogue: step toward a (99m)Tc-alternative to [18F]fluromisonidazole for detecting tumor hypoxia. Cancer biotherapy & radiopharmaceuticals, 2015, Volume: 30, Issue:2 Topics: Animals; Fibrosarcoma; Hypoxia; Mice; Misonidazole; Organotechnetium Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	2015
Synthesis of [(18)F]FMISO in a flow-through microfluidic reactor: Development and clinical application. Nuclear medicine and biology, 2015, Volume: 42, Issue:6 Topics: Adenocarcinoma; Aged; Carcinoma, Non-Small-Cell Lung; Fluorine Radioisotopes; Humans; Hypoxia; Image Processing, Computer-Assisted; Lung Neoplasms; Male; Microfluidics; Misonidazole; Pilot Projects; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiochemistry; Tissue Distribution	2015
18F-Fluoromisonidazole Quantification of Hypoxia in Human Cancer Patients Using Image-Derived Blood Surrogate Tissue Reference Regions. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Aorta; Brain Neoplasms; Cerebellum; Disease Progression; Female; Heart; Humans; Hypoxia; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Misonidazole; Neoplasms; Oxygen; Positron-Emission Tomography; Predictive Value of Tests; Proportional Hazards Models; Radiopharmaceuticals; Tissue Distribution; Treatment Outcome	2015
Comparison of [18F]-FMISO, [18F]-FAZA and [18F]-HX4 for PET imaging of hypoxia--a simulation study. Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9 Topics: Humans; Hypoxia; Imidazoles; Misonidazole; Models, Theoretical; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Triazoles	2015
(18)F-fluoromisonidazole PET reveals spatial and temporal heterogeneity of hypoxia in mouse models of human non-small-cell lung cancer. Future oncology (London, England), 2015, Volume: 11, Issue:20 Topics: Animals; Autoradiography; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Disease Models, Animal; Heterografts; Humans; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Nude; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals	2015
Evaluation of Tumor-associated Stroma and Its Relationship with Tumor Hypoxia Using Dynamic Contrast-enhanced CT and (18)F Misonidazole PET in Murine Tumor Models. Radiology, 2016, Volume: 278, Issue:3 Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Contrast Media; Disease Models, Animal; Female; Glioblastoma; Hypoxia; Immunohistochemistry; Mice; Misonidazole; Pancreatic Neoplasms; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiographic Image Interpretation, Computer-Assisted; Tomography, X-Ray Computed	2016
The accumulation mechanism of the hypoxia imaging probe "FMISO" by imaging mass spectrometry: possible involvement of low-molecular metabolites. Scientific reports, 2015, Nov-19, Volume: 5 Topics: Animals; Diagnostic Imaging; Hypoxia; Male; Mass Spectrometry; Metabolome; Metabolomics; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Molecular Probes; Molecular Weight; Neoplasms; Radionuclide Imaging; Reproducibility of Results; Tandem Mass Spectrometry; Tissue Distribution	2015
Feasibility of 18F-Fluoromisonidazole Kinetic Modeling in Head and Neck Cancer Using Shortened Acquisition Times. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:3 Topics: Algorithms; Animals; Carcinoma, Squamous Cell; Cohort Studies; Colorectal Neoplasms; Head and Neck Neoplasms; HT29 Cells; Humans; Hypoxia; Image Processing, Computer-Assisted; Misonidazole; Neoplasm Transplantation; Perfusion; Radionuclide Imaging; Radiopharmaceuticals; Rats; Reproducibility of Results; Retrospective Studies; ROC Curve	2016
Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury. JAMA neurology, 2016, 05-01, Volume: 73, Issue:5 Topics: Adult; Aged; Brain Injuries, Traumatic; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulation; Female; Humans; Hypoxia; Male; Middle Aged; Misonidazole; Oximetry; Oxygen; Positron-Emission Tomography	2016
Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O2 consumption? Medical physics, 2016, Volume: 43, Issue:7 Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Computer Simulation; Feasibility Studies; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Hypoxia; Mice, Nude; Misonidazole; Models, Biological; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment	2016
Hypoxia Radiotracer Produced Automatically in Dose-on-Demand Fashion. Current radiopharmaceuticals, 2016, Volume: 9, Issue:2 Topics: Animals; Automation; Chemistry Techniques, Synthetic; Drug Industry; Humans; Hypoxia; Mice; Misonidazole; Positron-Emission Tomography; Quality Control; Radiopharmaceuticals	2016
The role of necrosis, acute hypoxia and chronic hypoxia in Physics in medicine and biology, 2016, 12-21, Volume: 61, Issue:24 Topics: Computer Simulation; Humans; Hypoxia; Misonidazole; Models, Theoretical; Necrosis; Neoplasms; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Spheroids, Cellular	2016
Comparative pharmacokinetics, biodistribution, metabolism and hypoxia-dependent uptake of [18F]-EF3 and [18F]-MISO in rodent tumor models. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 89, Issue:3 Topics: Animals; Fluorine Radioisotopes; Hypoxia; Male; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiopharmaceuticals; Tissue Distribution	2008
[18F]EF3 is not superior to [18F]FMISO for PET-based hypoxia evaluation as measured in a rat rhabdomyosarcoma tumour model. European journal of nuclear medicine and molecular imaging, 2009, Volume: 36, Issue:2 Topics: Animals; Autoradiography; Biomarkers; Heart; Hypoxia; Male; Misonidazole; Myocardium; Nitroimidazoles; Positron-Emission Tomography; Rats; Reference Values; Rhabdomyosarcoma; Tissue Distribution	2009
Complementary but distinct roles for MRI and 18F-fluoromisonidazole PET in the assessment of human glioblastomas. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2009, Volume: 50, Issue:1 Topics: Adult; Aged; Female; Gadolinium; Glioblastoma; Humans; Hypoxia; Magnetic Resonance Imaging; Male; Middle Aged; Misonidazole; Neovascularization, Pathologic; Positron-Emission Tomography; Prognosis; Survival Analysis; Tumor Burden	2009
Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events. Proceedings of the National Academy of Sciences of the United States of America, 2009, Aug-18, Volume: 106, Issue:33 Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Luciferases; Mice; Misonidazole; Models, Biological; Neoplasm Transplantation; Positron-Emission Tomography; Response Elements; Time Factors; Transcription, Genetic	2009
Pharmacokinetic analysis of hypoxia (18)F-fluoromisonidazole dynamic PET in head and neck cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:1 Topics: Aged; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Neoplasm Staging; Plasma; Positron-Emission Tomography; Radiopharmaceuticals; Regional Blood Flow	2010
Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode. Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:7 Topics: Biosensing Techniques; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Hypoxia; Microchemistry; Microelectrodes; Misonidazole; Neoplasms; Oxygen; Positron-Emission Tomography; Sarcoma; Soft Tissue Neoplasms	2010
'Salvaged' stroke ischaemic penumbra shows significant injury: studies with the hypoxia tracer FMISO. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:3 Topics: Animals; Autoradiography; Brain; Brain Ischemia; Cerebral Infarction; Hypoxia; Misonidazole; Rats; Rats, Sprague-Dawley; Stroke; Time Factors; Tissue Distribution	2011
Modelling and simulation of [18F]fluoromisonidazole dynamics based on histology-derived microvessel maps. Physics in medicine and biology, 2011, Apr-07, Volume: 56, Issue:7 Topics: Diffusion; Finite Element Analysis; Hypoxia; Microvessels; Misonidazole; Models, Biological; Oxygen; Positron-Emission Tomography; Staining and Labeling	2011
Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images. Mathematical medicine and biology : a journal of the IMA, 2012, Volume: 29, Issue:1 Topics: Adult; Brain Neoplasms; Cell Proliferation; Computer Simulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Mathematical Concepts; Misonidazole; Models, Biological; Necrosis; Neoplasm Invasiveness; Neovascularization, Pathologic; Positron-Emission Tomography; Precision Medicine; Radiopharmaceuticals; User-Computer Interface	2012
Hypoxia imaging using PET and SPECT: the effects of anesthetic and carrier gas on [Cu]-ATSM, [Tc]-HL91 and [F]-FMISO tumor hypoxia accumulation. PloS one, 2011, Volume: 6, Issue:11 Topics: Adenocarcinoma; Anesthesia; Animals; Coordination Complexes; Copper Radioisotopes; Female; Fluorine Radioisotopes; Gases; Hypoxia; Mice; Mice, Inbred CBA; Misonidazole; Muscles; Neoplasms, Experimental; Organometallic Compounds; Organotechnetium Compounds; Oxygen; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Thiosemicarbazones; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	2011
Modelling and simulation of the influence of acute and chronic hypoxia on [18F]fluoromisonidazole PET imaging. Physics in medicine and biology, 2012, Mar-21, Volume: 57, Issue:6 Topics: Acute Disease; Chronic Disease; Computer Simulation; Fluorine Radioisotopes; Humans; Hypoxia; Misonidazole; Models, Biological; Neoplasms; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals	2012
Hypoxia assessed by 18F-fluoromisonidazole positron emission tomography in newly diagnosed gliomas. Nuclear medicine communications, 2012, Volume: 33, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Hypoxia; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiation-Sensitizing Agents; Retrospective Studies; Young Adult	2012
Evaluation of changes in the tumor microenvironment after sorafenib therapy by sequential histology and 18F-fluoromisonidazole hypoxia imaging in renal cell carcinoma. International journal of oncology, 2012, Volume: 41, Issue:5 Topics: Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Humans; Hypoxia; Kidney Neoplasms; Mice; Mice, Nude; Misonidazole; Niacinamide; Phenylurea Compounds; Platelet Endothelial Cell Adhesion Molecule-1; Radiopharmaceuticals; Sorafenib; Tumor Microenvironment; Xenograft Model Antitumor Assays	2012
High reproducibility of tumor hypoxia evaluated by 18F-fluoromisonidazole PET for head and neck cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:2 Topics: Adult; Aged; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypoxia; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Nuclear Medicine; Positron-Emission Tomography; Prognosis; Radiation Oncology; Radiopharmaceuticals; Reproducibility of Results; Time Factors	2013
Tumoral hypoxia in osteosarcoma in rats: preliminary study of blood oxygenation level-dependent functional MRI and 18F-misonidazole PET/CT with diffusion-weighted MRI correlation. AJR. American journal of roentgenology, 2013, Volume: 200, Issue:2 Topics: Animals; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Femoral Neoplasms; Hypoxia; Magnetic Resonance Imaging; Male; Misonidazole; Multimodal Imaging; Osteosarcoma; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tomography, X-Ray Computed	2013
Noninvasive assessment of hypoxia with 3-[18F]-fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([18F]-FMISO): a PET study in two experimental models of human glioma. Biological chemistry, 2013, Volume: 394, Issue:4 Topics: Glioma; Humans; Hypoxia; Immunohistochemistry; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Misonidazole; Positron-Emission Tomography	2013
Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models. Nuclear medicine communications, 2003, Volume: 24, Issue:5 Topics: Animals; Azides; Carcinoma, Squamous Cell; CHO Cells; Cricetinae; Cricetulus; Fibrosarcoma; Fructose; Glucaric Acid; Hypoxia; Male; Metabolic Clearance Rate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Organotechnetium Compounds; Oxygen; Potassium Cyanide; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution	2003
Assessing regional hypoxia in human renal tumours using 18F-fluoromisonidazole positron emission tomography. BJU international, 2005, Volume: 96, Issue:4 Topics: Adult; Aged; Carcinoma, Renal Cell; Female; Humans; Hypoxia; Immunohistochemistry; Kidney Neoplasms; Male; Middle Aged; Misonidazole; Neovascularization, Pathologic; Nephrectomy; Oxygen; Polarography; Positron-Emission Tomography; Radiopharmaceuticals	2005
Kinetic analysis of dynamic 18F-fluoromisonidazole PET correlates with radiation treatment outcome in head-and-neck cancer. BMC cancer, 2005, Dec-01, Volume: 5 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Processing, Computer-Assisted; Kinetics; Male; Middle Aged; Misonidazole; Models, Statistical; Positron-Emission Tomography; Radiation-Sensitizing Agents; Software; Treatment Outcome	2005
FDG--a marker of tumour hypoxia? A comparison with [18F]fluoromisonidazole and pO2-polarography in metastatic head and neck cancer. European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:12 Topics: Biomarkers, Tumor; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Neoplasm Metastasis; Oxygen; Polarography; Positron-Emission Tomography; Reference Standards	2006
A robotic synthesis of [18F]fluoromisonidazole ([18F]FMISO). Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2007, Volume: 65, Issue:6 Topics: Fluorine Radioisotopes; Hypoxia; Misonidazole; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Robotics	2007
Tumor hypoxia imaging in orthotopic liver tumors and peritoneal metastasis: a comparative study featuring dynamic 18F-MISO and 124I-IAZG PET in the same study cohort. European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:1 Topics: Animals; Disease Models, Animal; Half-Life; Hypoxia; Liver Neoplasms, Experimental; Misonidazole; Monosaccharides; Nitroimidazoles; Peritoneal Neoplasms; Positron-Emission Tomography; Rats; Tissue Distribution	2008
Hypoxia-enhanced reduction and covalent binding of [2-3H]misonidazole in the perfused rat liver. Biochemical pharmacology, 1984, Apr-15, Volume: 33, Issue:8 Topics: Animals; DNA; Glutathione; Hypoxia; Liver; Male; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Oxygen; Perfusion; Protein Binding; Rats; Rats, Inbred Strains; RNA	1984
Hypoxic cell radiosensitizers in the treatment of malignant brain tumors. Neurosurgery, 1980, Volume: 6, Issue:5 Topics: Animals; Brain Neoplasms; Cricetinae; DNA; Glioblastoma; Humans; Hypoxia; In Vitro Techniques; Metronidazole; Misonidazole; Oxygen Consumption; Radiation-Sensitizing Agents	1980
Sensitising effect of misonidazole on NHIK 1922 cells irradiated in vitro or as solid tumour in athymic nude mice. Acta radiologica. Oncology, 1981, Volume: 20, Issue:2 Topics: Animals; Cell Line; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Hypoxia; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Protective Agents	1981
The detection and measurement of hypoxic cells in solid tumors. Cancer, 1984, Dec-01, Volume: 54, Issue:11 Topics: Anaerobiosis; Animals; Brain Neoplasms; Carbon Radioisotopes; Cell Line; Cell Survival; Cricetinae; Cricetulus; Humans; Hypoxia; Lung; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Mice; Misonidazole; Neoplasms; Radiation-Sensitizing Agents; Rats; Tomography, Emission-Computed	1984
Influence of misonidazole on survival of wild-type and radiosensitive mutants of yeast. Mutation research, 1983, Volume: 108, Issue:1-3 Topics: Dose-Response Relationship, Drug; Gamma Rays; Haploidy; Hypoxia; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Saccharomyces cerevisiae	1983
The effect of a hypoxic cell sensitizer on cancer radiotherapy: an analysis by a model. Strahlentherapie, 1984, Volume: 160, Issue:10 Topics: Humans; Hypoxia; Mathematics; Misonidazole; Models, Theoretical; Neoplasms; Nitroimidazoles	1984
Radiosensitizing drugs in relation to individualized treatment. Strahlentherapie, 1984, Volume: 160, Issue:11 Topics: Alkylating Agents; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Hypoxia; In Vitro Techniques; Misonidazole; Neoplasms; Nervous System; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Sulfhydryl Reagents	1984
Polarographic measurement of misonidazole in mouse mammary tumors. The Tokai journal of experimental and clinical medicine, 1984, Volume: 9, Issue:3 Topics: Animals; Half-Life; Hypoxia; In Vitro Techniques; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Polarography; Tissue Distribution	1984
Development of new hypoxic cell sensitizers: amides of nitrobenzoic acid with spermidine and spermine. Experientia, 1983, Oct-15, Volume: 39, Issue:10 Topics: Cell Survival; HeLa Cells; Humans; Hypoxia; Misonidazole; Radiation-Sensitizing Agents; Spermidine; Spermine	1983
[Radiosensitization of hypoxic tumor cells with special reference to head and neck cancers]. Wiener klinische Wochenschrift, 1983, Aug-05, Volume: 95, Issue:15 Topics: Half-Life; Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents	1983
Role of glutathione in the hypoxic cell cytotoxicity of misonidazole. Cancer research, 1983, Volume: 43, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Cricetulus; Female; Glutathione; Glutathione Transferase; Hypoxia; Maleates; Misonidazole; Nitroimidazoles; Ovary	1983
Lung tumorigenic response of strain A mice exposed to hypoxic cell sensitizers alone and in combination with gamma-radiation. Cancer research, 1983, Volume: 43, Issue:1 Topics: Adenoma; Animals; Hypoxia; Lung; Lung Neoplasms; Metronidazole; Mice; Mice, Inbred A; Misonidazole; Neoplasms, Radiation-Induced; Radiation-Sensitizing Agents	1983
Influence of hypoxia on the metabolism and excretion of misonidazole by the isolated perfused rat liver--a model system. Biochemical pharmacology, 1983, May-15, Volume: 32, Issue:10 Topics: Animals; Chromatography, High Pressure Liquid; Hypoxia; Kinetics; Liver; Male; Misonidazole; Nitroimidazoles; Rats	1983
Reduction of misonidazole and its derivatives by xanthine oxidase. Biochemical pharmacology, 1981, Apr-15, Volume: 30, Issue:8 Topics: Hypoxia; In Vitro Techniques; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Xanthine Oxidase	1981
Comparative misonidazole metabolism in anaerobic bacteria and hypoxic Chinese hamster lung fibroblast (V-79-473) cells. Biochemical pharmacology, 1982, Feb-01, Volume: 31, Issue:3 Topics: Animals; Biotransformation; Cells, Cultured; Cricetinae; Enterobacteriaceae; Fibroblasts; Hypoxia; Lung; Mesocricetus; Misonidazole; Mutagens; Nitroimidazoles; Oxidation-Reduction	1982
Radiosensitization of hypoxic tumor cells by depletion of intracellular glutathione. Science (New York, N.Y.), 1982, Aug-06, Volume: 217, Issue:4559 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Drug Synergism; Glutathione; Hypoxia; Maleates; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms, Experimental; Oxygen Consumption	1982
The interaction of misonidazole with radiation, chemotherapeutic agents, or heat: a preliminary report. Cancer clinical trials, 1980,Fall, Volume: 3, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Cisplatin; Cricetinae; Hot Temperature; Hypoxia; Mechlorethamine; Melphalan; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1980
Radiosensitizing effect of 2,4-dinitroimidazole-1-ethanol and its cytotoxicity in HeLa S3 cells. Strahlentherapie, 1981, Volume: 157, Issue:7 Topics: HeLa Cells; Humans; Hypoxia; Imidazoles; Misonidazole; Radiation-Sensitizing Agents	1981
Radiation-enhanced cytotoxicity of misonidazole. Radiation research, 1981, Volume: 88, Issue:2 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Female; Hypoxia; Misonidazole; Nitroimidazoles; Ovary; X-Rays	1981
Combined effects of misonidazole radiosensitization and hypoxic cell toxicity in mammalian cells. Radiation research, 1981, Volume: 88, Issue:2 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Female; Hypoxia; Misonidazole; Nitroimidazoles; Ovary; X-Rays	1981
The effect of combinations of nitroaromatic and nitroxyl radiosensitizers on the radiation survival response of Chinese hamster cells, V.79-753B, in vitro. Radiation research, 1981, Volume: 88, Issue:2 Topics: Acetophenones; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cyclic N-Oxides; Female; Hypoxia; Misonidazole; Nitroimidazoles; Ovary; Radiation-Sensitizing Agents; Spin Labels	1981
Measurements of in vivo effects of an electron-affinic radiosensitizer using a double tracer technique. Strahlentherapie, 1980, Volume: 156, Issue:8 Topics: Animals; Female; Hypoxia; Methods; Mice; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Sarcoma 180	1980
Testing of hypoxic cell radiosensitizers in vivo. Cancer clinical trials, 1980,Summer, Volume: 3, Issue:2 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Humans; Hypoxia; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1980
Cytotoxic and radiosensitizing effects of misonidazole on hematopoiesis in normal and tumor-bearing mice. International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:9 Topics: Animals; Colony-Forming Units Assay; Dose-Response Relationship, Radiation; Hematopoiesis; Hematopoietic Stem Cells; Hypoxia; Lung Neoplasms; Male; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles	1980
A modeling approach for quantifying tumor hypoxia with [F-18]fluoromisonidazole PET time-activity data. Medical physics, 1995, Volume: 22, Issue:7 Topics: Animals; Biological Transport, Active; Biophysical Phenomena; Biophysics; Computer Simulation; Evaluation Studies as Topic; Humans; Hypoxia; Misonidazole; Models, Biological; Monte Carlo Method; Neoplasms; Radiation-Sensitizing Agents; Rats; Tomography, Emission-Computed	1995
Characterization of induced pulpal hypoxia using 3H-misonidazole. Journal of endodontics, 1994, Volume: 20, Issue:12 Topics: Analysis of Variance; Animals; Cell Hypoxia; Dental Pulp Diseases; Hyperbaric Oxygenation; Hypoxia; Male; Misonidazole; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tritium	1994
Low concentrations of nitroimidazoles: effective radiosensitizers at low doses. International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1 Topics: Animals; CHO Cells; Cricetinae; Etanidazole; Hypoxia; In Vitro Techniques; Misonidazole; Nimorazole; Radiation-Sensitizing Agents	1994
An efficient radiosynthesis of [18F]fluoromisonidazole. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 1993, Volume: 44, Issue:8 Topics: Fluorine Radioisotopes; Hypoxia; Isotope Labeling; Misonidazole; Tomography, Emission-Computed	1993
Comparing techniques of measuring tumor hypoxia in different murine tumors: Eppendorf pO2 Histograph, [3H]misonidazole binding and paired survival assay. Radiation research, 1996, Volume: 145, Issue:4 Topics: Animals; Cell Survival; Female; Hypoxia; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Polarography	1996
Anomalous patterns of nitroimidazole binding adjacent to necrosis in human glioma xenografts: possible role of decreased oxygen consumption. British journal of cancer, 1997, Volume: 75, Issue:3 Topics: Animals; Antineoplastic Agents; Autoradiography; Binding Sites; Cell Line; Glioblastoma; Glioma; Humans; Hypoxia; Mice; Mice, SCID; Misonidazole; Necrosis; Oxygen Consumption; Rats; Rats, Nude; Transplantation, Heterologous; Tritium; Tumor Cells, Cultured	1997
Influence of oxygen on radiation-induced DNA damage in testicular cells of C3H mice. International journal of radiation biology, 1997, Volume: 71, Issue:3 Topics: Animals; DNA; DNA Damage; DNA Repair; Hypoxia; Male; Mice; Mice, Inbred C3H; Misonidazole; Oxygen; Sertoli Cells; Spermatids; Spermatocytes; Spleen; Testis; Tumor Cells, Cultured	1997
Variable presence of hypoxia in M006 human glioma spheroids and in spheroids and xenografts of clonally derived sublines. British journal of cancer, 1998, Volume: 78, Issue:10 Topics: Animals; Brain Neoplasms; Clone Cells; Deuterium; Glioma; Humans; Hypoxia; Mice; Mice, SCID; Misonidazole; Necrosis; Radiation-Sensitizing Agents; Spheroids, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured	1998
Feasibility of detecting hypoxia in experimental mouse tumours with 18F-fluorinated tracers and positron emission tomography--a study evaluating [18F]Fluoro-2-deoxy-D-glucose. Acta oncologica (Stockholm, Sweden), 2000, Volume: 39, Issue:5 Topics: Animals; Binding Sites; Carbon Dioxide; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Hypoxia; Mammary Neoplasms, Experimental; Mice; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tomography, Emission-Computed	2000
Hypoxia regulates avian cardiac Arnt and HIF-1alpha mRNA expression. Biochemical and biophysical research communications, 2001, Mar-30, Volume: 282, Issue:2 Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Base Sequence; Chick Embryo; Disease Models, Animal; DNA Primers; DNA-Binding Proteins; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Misonidazole; Molecular Sequence Data; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nuclear Proteins; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Transcription Factors	2001
Statistical parametric mapping of hypoxic tissue identified by [(18)F]fluoromisonidazole and positron emission tomography following acute ischemic stroke. NeuroImage, 2002, Volume: 16, Issue:2 Topics: Acute Disease; Aged; Brain; Brain Ischemia; Female; Fluorine Radioisotopes; Humans; Hypoxia; Male; Middle Aged; Misonidazole; Reference Values; Statistics as Topic; Stroke; Tomography, Emission-Computed	2002
Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours. Gene therapy, 2002, Volume: 9, Issue:14 Topics: Animals; Combined Modality Therapy; Female; Fibrosarcoma; Genetic Therapy; Genetic Vectors; Humans; Hypoxia; Mice; Mice, Nude; Misonidazole; NADPH-Ferrihemoprotein Reductase; Neoplasm Transplantation; Nitroimidazoles; Prodrugs; Radiation Tolerance; Radiation-Sensitizing Agents; Transplantation, Heterologous; Tumor Cells, Cultured	2002
Hypoxic-cell sensitisers. Lancet (London, England), 1978, Sep-16, Volume: 2, Issue:8090 Topics: Cell Survival; Humans; Hypoxia; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen Consumption; Radiation Tolerance	1978
Hypoxic-cell sensitisers. Lancet (London, England), 1978, Oct-21, Volume: 2, Issue:8095 Topics: Dose-Response Relationship, Drug; Drug Evaluation; Humans; Hypoxia; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles	1978
The effect of bleomycin on aerated and hypoxic cells in vitro, in combination with irradiation. International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:9 Topics: Animals; Bleomycin; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Drug Synergism; Hot Temperature; Hypoxia; Misonidazole; Oxygen; Time Factors	1979
Influence of the hypoxic cell sensitizer misonidazole on the proliferation of well-oxygenated cells in vitro during prolonged exposure. British journal of cancer, 1979, Volume: 40, Issue:5 Topics: Animals; Cell Cycle; Cell Division; Cell Line; Hypoxia; Mice; Misonidazole; Mitosis; Nitroimidazoles; Osteosarcoma; Oxygen; Sarcoma, Experimental; Time Factors	1979
A metabolite of the 2-nitroimidazole misonidazole with radiosensitizing properties. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1978, Volume: 34, Issue:1 Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Hypoxia; Lung; Mice; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Radiation Tolerance	1978
The effects of single and fractionated doses of X-rays and neutrons on the oesophagus. European journal of cancer, 1979, Volume: 15, Issue:4 Topics: Animals; Esophagus; Fast Neutrons; Female; Hypoxia; Mice; Misonidazole; Oxygen; Radiation Dosage; Radiation Injuries, Experimental; Radiation Tolerance; Relative Biological Effectiveness; X-Rays	1979
[New aspects of radiotherapy. I. Significance of hypoxia in irradiation of solid tumors]. Ugeskrift for laeger, 1979, Apr-09, Volume: 141, Issue:15 Topics: Dose-Response Relationship, Radiation; Hot Temperature; Humans; Hyperbaric Oxygenation; Hypoxia; Misonidazole; Neoplasms; Nitroimidazoles	1979
Influence of misonidazole on the radiosensitivity of a human melanoma in nude mice: time-dependent increase in surviving fraction. International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:4 Topics: Animals; Cell Survival; Female; Humans; Hypoxia; In Vitro Techniques; Melanoma; Mice; Mice, Nude; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Time Factors	1979
Radiosensitization of mammalian cells by misonidazole and oxygen: DNA damage exposed by Micrococcus luteus enzymes. Radiation research, 1979, Volume: 79, Issue:3 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA; Gamma Rays; Hypoxia; Micrococcus; Misonidazole; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Ultraviolet Rays	1979
Resistance to adriamycin in multicellular spheroids. International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:8 Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Doxorubicin; Drug Resistance; Female; Hypoxia; Mammary Neoplasms, Experimental; Mice; Misonidazole	1979
Studies on the toxicity and radiosensitizing ability of misonidazole under conditions of prolonged incubation. Radiation research, 1978, Volume: 75, Issue:3 Topics: Cell Survival; Cells, Cultured; Cobalt Radioisotopes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Hypoxia; Misonidazole; Nitroimidazoles; Radiation Tolerance; Temperature; Time Factors	1978
In vitro studies on the radioresistance of oxic and hypoxic cells in the presence of both radioprotective and radiosensitizing drugs. Radiation research, 1978, Volume: 75, Issue:3 Topics: Cell Survival; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Combinations; Hypoxia; Misonidazole; Oxygen; Radiation Tolerance; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy; X-Rays	1978
Evaluation of the role of cellular hypoxia in sepsis by the hypoxic marker [18F]fluoromisonidazole. The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 2 Topics: Animals; Female; Fluorine Radioisotopes; Gases; Hypoxia; Infections; Misonidazole; Rats; Rats, Inbred Strains; Regional Blood Flow; Time Factors	1991
Synthesis of an (iodovinyl)misonidazole derivative for hypoxia imaging. Journal of medicinal chemistry, 1991, Volume: 34, Issue:7 Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Cricetulus; Hypoxia; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms, Experimental; Radiation-Sensitizing Agents; Structure-Activity Relationship	1991
KIH-802, an acetohydroxamic acid derivative of 2-nitroimidazole, as a new potent hypoxic cell radiosensitizer: radiosensitizing activity, acute toxicity, and pharmacokinetics. Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:2 Topics: Animals; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Etanidazole; Female; Hydroxamic Acids; Hypoxia; Injections, Intravenous; Lethal Dose 50; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1990
Fluoromisonidazole. A metabolic marker of myocyte hypoxia. Circulation research, 1990, Volume: 67, Issue:1 Topics: Animals; Creatine Kinase; Hypoxia; Misonidazole; Myocardium; Oxygen; Partial Pressure; Reference Values	1990
Modulation of prostaglandin biosynthesis in hypoxic murine mammary adenocarcinoma cells by misonidazole. Cancer research, 1989, Jul-15, Volume: 49, Issue:14 Topics: Adenocarcinoma; Anaerobiosis; Animals; Cell Line; Hypoxia; Indomethacin; Kinetics; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Misonidazole; Prostaglandins; Tumor Cells, Cultured	1989
Enhanced binding of the hypoxic cell marker [3H]fluoromisonidazole in ischemic myocardium. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989, Volume: 30, Issue:2 Topics: Animals; Coronary Disease; Dogs; Hypoxia; Misonidazole; Myocardium; Tritium	1989
Myocardial kinetics of fluorine-18 misonidazole: a marker of hypoxic myocardium. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989, Volume: 30, Issue:3 Topics: Animals; Coronary Disease; Dogs; Fluorine Radioisotopes; Hypoxia; Male; Misonidazole; Myocardium; Rabbits; Radionuclide Imaging	1989
Detection of an intrinsic marker in hypoxic cells. Cancer research, 1989, Sep-15, Volume: 49, Issue:18 Topics: Animals; Autoradiography; Biomarkers; Cell Line; Culture Techniques; Hypoxia; Misonidazole; Organelles; Tritium; Tumor Cells, Cultured	1989
Metabolic binding of misonidazole to mouse tissues. Comparison between labels on the ring and side chain, and the production of tritiated water. Biochemical pharmacology, 1989, Feb-15, Volume: 38, Issue:4 Topics: Aerobiosis; Animals; Chromatography, High Pressure Liquid; Hypoxia; Mice; Mice, Inbred BALB C; Misonidazole; Neoplasms, Experimental; Solubility; Tissue Distribution	1989
Changes in ultrastructure and function of hypoxic V79 fibroblast cells after treatment with misonidazole. Cancer, 1985, Feb-15, Volume: 55, Issue:4 Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Electron Transport Complex IV; Fibroblasts; Hypoxia; Microscopy, Electron; Misonidazole; Mitochondrial Swelling; Nitroimidazoles; Oxygen; Time Factors	1985
Synthesis and biodistribution of 18F-labeled fluoronitroimidazoles: potential in vivo markers of hypoxic tissue. International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1986, Volume: 37, Issue:7 Topics: Animals; Fluorine; Hypoxia; Metronidazole; Misonidazole; Nitroimidazoles; Radioisotopes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution	1986
Oxic and hypoxic cells in a murine squamous cell carcinoma. Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:4 Topics: Animals; Carcinoma, Squamous Cell; Constriction; Dose-Response Relationship, Radiation; Female; Hypoxia; Idoxuridine; Iodine Radioisotopes; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Oxygen Consumption; Skin Neoplasms	1988
The adaptive response of mouse tumours to anaemia and retransfusion. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1987, Volume: 51, Issue:4 Topics: Anemia; Animals; Female; Hypoxia; Mice; Misonidazole; Neoplasms, Experimental; Radiotherapy Dosage	1987
In vitro and in vivo radiosensitizing effects of 2-nitroimidazole derivatives with sugar component. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1987, Volume: 163, Issue:6 Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Combined Modality Therapy; Cricetinae; Cricetulus; HeLa Cells; Hypoxia; Mice; Mice, Inbred ICR; Misonidazole; Radiation-Sensitizing Agents; Sarcoma 180	1987
Chloronitroimidazoles as radiosensitizers of hypoxic cells in vitro. Neoplasma, 1987, Volume: 34, Issue:3 Topics: Aerobiosis; Animals; Cell Survival; Chlorine; Glutathione; Hypoxia; Metronidazole; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Structure-Activity Relationship	1987
Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells. Radiation research, 1987, Volume: 111, Issue:2 Topics: Animals; Autoradiography; Biotransformation; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hypoxia; Mice; Mice, Inbred C3H; Misonidazole; Oxygen; Radionuclide Imaging; Sarcoma, Experimental; Tritium	1987
Oxygen dependence of binding of misonidazole to rodent and human tumors in vitro. Cancer research, 1987, Oct-15, Volume: 47, Issue:20 Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Humans; Hypoxia; Male; Mice; Mice, Inbred BALB C; Misonidazole; Oxygen; Prostatic Neoplasms	1987
RSU 1069, a nitroimidazole containing an aziridine group. Bioreduction greatly increases cytotoxicity under hypoxic conditions. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; DNA; Female; Glutathione; Hydrolysis; Hypoxia; Kinetics; Misonidazole; Oxidation-Reduction; Radiation-Sensitizing Agents; Structure-Activity Relationship; X-Rays	1986
Synthesis and characterization of congeners of misonidazole for imaging hypoxia. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1987, Volume: 28, Issue:1 Topics: Animals; Bromine; Chromatography, Gel; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Fluorine; Hypoxia; Isotope Labeling; Mice; Misonidazole; Neoplasms, Experimental; Radioisotopes; Radionuclide Imaging; Tissue Distribution; Tritium	1987
The interaction between radiation and complexes of cis-Pt(II) and Rh(II): studies at the molecular and cellular level. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:4 Topics: Animals; Cell Survival; Cisplatin; Combined Modality Therapy; Cricetinae; DNA; Female; Glutathione; Hypoxia; Mice; Misonidazole; Neoplasms, Experimental; Oxidation-Reduction; Radiation-Sensitizing Agents; Rhodium; Spectrum Analysis	1985
Sensitization of cancer chemotherapeutic agents by nitroheterocyclics. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Survival; Drug Synergism; Heterocyclic Compounds; Hydroxamic Acids; Hypoxia; Lomustine; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Effect of hypoxic cell radiosensitizers on glutathione level and related enzyme activities in isolated rat hepatocytes. Life sciences, 1985, Aug-19, Volume: 37, Issue:7 Topics: Animals; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hydrogen Peroxide; Hypoxia; Imidazoles; Liver; Male; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rats, Inbred Strains; Time Factors	1985
Glutathione and misonidazole: independent or interactive mechanisms of action? The British journal of radiology, 1985, Volume: 58, Issue:688 Topics: Glutathione; Hypoxia; Misonidazole; Oxygen; Radiation Tolerance	1985
Glutathione depletion and misonidazole efficiency. The British journal of radiology, 1985, Volume: 58, Issue:688 Topics: Glutathione; Hypoxia; Misonidazole; Oxygen; Radiation Tolerance	1985
Hypoxic fraction and binding of misonidazole in EMT6/Ed multicellular tumor spheroids. Radiation research, 1985, Volume: 103, Issue:1 Topics: Animals; Autoradiography; Cell Line; Cell Survival; Hypoxia; Misonidazole; Neoplasms, Experimental; Oxygen; Time Factors	1985