mirtazapine has been researched along with Torsade de Pointes in 4 studies
Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Citalopram is a selective serotonin reuptake inhibitor with a favorable cardiac-safety profile." | 1.38 | Prolonged QTc interval and torsades de pointes induced by citalopram. ( Abuissa, H; Airey, K; Alla, V; Deshmukh, A; Ulveling, K, 2012) |
| "Citalopram overdose was more likely to be associated with QT higher than the nomogram compared with the other agents (difference 7." | 1.36 | Evaluation of a QT nomogram for risk assessment after antidepressant overdose. ( Bateman, DN; Graham, A; Gray, J; Howell, C; Waring, WS; Wilson, AD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ryan, K | 1 |
| Benz, P | 1 |
| Zosel, A | 1 |
| Farkas, A | 1 |
| Theobald, J | 1 |
| Al-Khalil, M | 1 |
| Sack, A | 1 |
| Elson, R | 1 |
| Pleat, J | 1 |
| Waring, WS | 1 |
| Graham, A | 1 |
| Gray, J | 1 |
| Wilson, AD | 1 |
| Howell, C | 1 |
| Bateman, DN | 1 |
| Deshmukh, A | 1 |
| Ulveling, K | 1 |
| Alla, V | 1 |
| Abuissa, H | 1 |
| Airey, K | 1 |
4 other studies available for mirtazapine and Torsade de Pointes
| Article | Year |
|---|---|
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long | 2022 |
A 5-year single-centre retrospective study of potential drug interactions in burns inpatients with psychiatric comorbidities.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents; Arrhythmias, Cardiac; Burns; Comorbidity; Drug Int | 2020 |
Evaluation of a QT nomogram for risk assessment after antidepressant overdose.
Topics: Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Drug Overdose; Electrocardiography; Female; | 2010 |
Prolonged QTc interval and torsades de pointes induced by citalopram.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Depre | 2012 |