Page last updated: 2024-10-31

mirtazapine and Stroke

mirtazapine has been researched along with Stroke in 3 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"Patients with ischemic stroke received either 30 mg mirtazapine or no antidepressant medication from day 1 after the stroke in an open, randomized study design."9.11Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke. ( Bohrer, E; Heuser, I; Niedermaier, N; Schlattmann, P; Schulte, K, 2004)
"Mirtazapine may be a probably effective treatment in stroke survivors with obstructive sleep apnea who refuse nasal CPAP treatment."6.73Success and failure of mirtazapine as alternative treatment in elderly stroke patients with sleep apnea-a preliminary open trial. ( Brunner, H, 2008)
"Patients with ischemic stroke received either 30 mg mirtazapine or no antidepressant medication from day 1 after the stroke in an open, randomized study design."5.11Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke. ( Bohrer, E; Heuser, I; Niedermaier, N; Schlattmann, P; Schulte, K, 2004)
" He had an ischemic stroke and developed a psychotic condition that was successfully treated by lowering the cabergoline and administering quetiapine and mirtazapine together."3.91Giant cabergoline-resistant prolactinoma in a man who presented with a psychotic episode during treatment: a case report. ( Casulari, LA; de Castro, LF; de Fátima Magalhães Gonzaga, M; Kessler, IM; Mendonça, JL, 2019)
"Mirtazapine may be a probably effective treatment in stroke survivors with obstructive sleep apnea who refuse nasal CPAP treatment."2.73Success and failure of mirtazapine as alternative treatment in elderly stroke patients with sleep apnea-a preliminary open trial. ( Brunner, H, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casulari, LA1
de Castro, LF1
Kessler, IM1
Mendonça, JL1
de Fátima Magalhães Gonzaga, M1
Niedermaier, N1
Bohrer, E1
Schulte, K1
Schlattmann, P1
Heuser, I1
Brunner, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Agomelatine in the Prevention of Poststroke Depression[NCT05426304]Phase 4420 participants (Anticipated)Interventional2022-10-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for mirtazapine and Stroke

ArticleYear
Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:12

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Administration Schedule; Female; F

2004
Success and failure of mirtazapine as alternative treatment in elderly stroke patients with sleep apnea-a preliminary open trial.
    Sleep & breathing = Schlaf & Atmung, 2008, Volume: 12, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Body Mass Index; Continuous Positive Airway Pressure; Electromyo

2008

Other Studies

1 other study available for mirtazapine and Stroke

ArticleYear
Giant cabergoline-resistant prolactinoma in a man who presented with a psychotic episode during treatment: a case report.
    Journal of medical case reports, 2019, Jun-16, Volume: 13, Issue:1

    Topics: Cabergoline; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans;

2019