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mirtazapine and Renal Insufficiency, Chronic

mirtazapine has been researched along with Renal Insufficiency, Chronic in 3 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)

Research Excerpts

ExcerptRelevanceReference
" Although, compared to baseline, both gabapentin and mirtazapine treatment resulting in significant improvement in VAS scores, decreasing in pruritus severity was significantly greater in the mirtazapine treatment period compared with the gabapentin treatment period (Pā€‰<ā€‰0."9.34Effect of mirtazapine on pruritus in patients on hemodialysis: a cross-over pilot study. ( Gholyaf, M; Mehrpooya, M; Mirjalili, M; Mohammadi, Y; Sheikh, V; Yasrebifar, F, 2020)
" Although, compared to baseline, both gabapentin and mirtazapine treatment resulting in significant improvement in VAS scores, decreasing in pruritus severity was significantly greater in the mirtazapine treatment period compared with the gabapentin treatment period (Pā€‰<ā€‰0."5.34Effect of mirtazapine on pruritus in patients on hemodialysis: a cross-over pilot study. ( Gholyaf, M; Mehrpooya, M; Mirjalili, M; Mohammadi, Y; Sheikh, V; Yasrebifar, F, 2020)
"Cats with chronic kidney disease (CKD) often experience inappetence and vomiting and might benefit from the administration of mirtazapine, a medication with appetite stimulant and anti-nausea properties."5.17Mirtazapine as an appetite stimulant and anti-emetic in cats with chronic kidney disease: a masked placebo-controlled crossover clinical trial. ( Lunn, KF; Quimby, JM, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Gholyaf, M1
Sheikh, V1
Yasrebifar, F1
Mohammadi, Y1
Mirjalili, M1
Mehrpooya, M1
Quimby, JM2
Benson, KK1
Summers, SC1
Saffire, A1
Herndon, AK1
Bai, S1
Gustafson, DL1
Lunn, KF1

Trials

3 trials available for mirtazapine and Renal Insufficiency, Chronic

ArticleYear
Effect of mirtazapine on pruritus in patients on hemodialysis: a cross-over pilot study.
    International urology and nephrology, 2020, Volume: 52, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cross-Over Studies; Female; Histamine H1 Antagonists; Humans; Male;

2020
Assessment of compounded transdermal mirtazapine as an appetite stimulant in cats with chronic kidney disease.
    Journal of feline medicine and surgery, 2020, Volume: 22, Issue:4

    Topics: Administration, Cutaneous; Animals; Appetite Stimulants; Cat Diseases; Cats; Double-Blind Method; Mi

2020
Mirtazapine as an appetite stimulant and anti-emetic in cats with chronic kidney disease: a masked placebo-controlled crossover clinical trial.
    Veterinary journal (London, England : 1997), 2013, Volume: 197, Issue:3

    Topics: Animals; Anorexia; Antiemetics; Appetite Stimulants; Cat Diseases; Cats; Cross-Over Studies; Female;

2013