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mirtazapine and REM Sleep Behavior Disorder

mirtazapine has been researched along with REM Sleep Behavior Disorder in 3 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

REM Sleep Behavior Disorder: A disorder characterized by episodes of vigorous and often violent motor activity during REM sleep (SLEEP, REM). The affected individual may inflict self injury or harm others, and is difficult to awaken from this condition. Episodes are usually followed by a vivid recollection of a dream that is consistent with the aggressive behavior. This condition primarily affects adult males. (From Adams et al., Principles of Neurology, 6th ed, p393)

Research Excerpts

ExcerptRelevanceReference
"Shortly after initiation of mirtazapine (a noradrenergic and serotonergic antidepressant) treatment in four patients with parkinsonism, the authors observed the appearance of REM sleep behavior disorder (RBD)."7.72Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. ( D'Andreamatteo, G; Iacono, D; Luciano, AL; Onofrj, M; Thomas, A, 2003)
"Shortly after initiation of mirtazapine (a noradrenergic and serotonergic antidepressant) treatment in four patients with parkinsonism, the authors observed the appearance of REM sleep behavior disorder (RBD)."3.72Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. ( D'Andreamatteo, G; Iacono, D; Luciano, AL; Onofrj, M; Thomas, A, 2003)
"Haloperidol was discontinued, but mirtazapine was continued, and the vivid dream activity persisted; however, reality testing when awake was intact."1.36Acute psychosis associated with dissociated sleep-wakefulness state after mirtazapine treatment. ( Felthous, AR; Hoevet, R; Wenger, PJ, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Felthous, AR1
Wenger, PJ1
Hoevet, R1
Onofrj, M1
Luciano, AL1
Thomas, A1
Iacono, D1
D'Andreamatteo, G1
Nash, JR1
Wilson, SJ1
Potokar, JP1
Nutt, DJ1

Other Studies

3 other studies available for mirtazapine and REM Sleep Behavior Disorder

ArticleYear
Acute psychosis associated with dissociated sleep-wakefulness state after mirtazapine treatment.
    Pharmacotherapy, 2010, Volume: 30, Issue:4

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Depressive Disorder, Major; Dreams; Ha

2010
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
    Neurology, 2003, Jan-14, Volume: 60, Issue:1

    Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Electroencephalography; Humans; Levodopa; Male;

2003
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
    Neurology, 2003, Oct-28, Volume: 61, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Drug Administration Schedule; Hu

2003