Page last updated: 2024-10-31

mirtazapine and Psychomotor Agitation

mirtazapine has been researched along with Psychomotor Agitation in 6 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.

Research Excerpts

ExcerptRelevanceReference
"This parallel-group, double-blind, placebo-controlled trial-the Study of Mirtazapine for Agitated Behaviours in Dementia trial (SYMBAD)-was done in 26 UK centres."9.41Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial. ( Ballard, C; Banerjee, S; Bentham, P; Burns, A; Farina, N; Fox, C; Francis, P; Henderson, C; High, J; Howard, R; Knapp, M; Leroi, I; Livingston, G; Nilforooshan, R; Nurock, S; O'Brien, J; Price, A; Shepstone, L; Stirling, S; Swart, AM; Tabet, N; Telling, T; Thomas, AJ, 2021)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."5.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"This parallel-group, double-blind, placebo-controlled trial-the Study of Mirtazapine for Agitated Behaviours in Dementia trial (SYMBAD)-was done in 26 UK centres."5.41Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial. ( Ballard, C; Banerjee, S; Bentham, P; Burns, A; Farina, N; Fox, C; Francis, P; Henderson, C; High, J; Howard, R; Knapp, M; Leroi, I; Livingston, G; Nilforooshan, R; Nurock, S; O'Brien, J; Price, A; Shepstone, L; Stirling, S; Swart, AM; Tabet, N; Telling, T; Thomas, AJ, 2021)
"Antipsychotic-induced akathisia is optimally managed by reducing the medication dose or switching to a second generation antipsychotic that is less prone to inducing akathisia."2.72Struggling to find Effective Pharmacologic Options for Akathisia? B-CALM! ( Birur, B; Fargason, RE; Thippaiah, SM, 2021)
"Mirtazapine-treated patients demonstrated a statistically significant (p < or = ."2.40A meta-analysis of eight randomized, double-blind, controlled clinical trials of mirtazapine for the treatment of patients with major depression and symptoms of anxiety. ( Barkin, RL; Fawcett, J, 1998)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."1.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Banerjee, S1
High, J1
Stirling, S1
Shepstone, L1
Swart, AM1
Telling, T1
Henderson, C1
Ballard, C1
Bentham, P1
Burns, A1
Farina, N1
Fox, C1
Francis, P1
Howard, R1
Knapp, M1
Leroi, I1
Livingston, G1
Nilforooshan, R1
Nurock, S1
O'Brien, J1
Price, A1
Thomas, AJ1
Tabet, N1
Naguy, A1
Moodliar-Rensburg, S1
Alamiri, B1
Thippaiah, SM1
Fargason, RE1
Birur, B1
de Witte, LD1
Dekker, D1
Veraart, J1
Kromkamp, M1
Kaasjager, K1
Vinkers, CH1
Fawcett, J1
Barkin, RL2
Davis, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pragmatic, Multi Centre, Double-blind, Placebo Controlled Randomised Trial to Assess the Safety, Clinical and Cost Effectiveness of Mirtazapine in Patients With Alzheimer's Disease (AD) and Agitated Behaviours[NCT03031184]Phase 3207 participants (Actual)Interventional2017-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for mirtazapine and Psychomotor Agitation

ArticleYear
Struggling to find Effective Pharmacologic Options for Akathisia? B-CALM!
    Psychopharmacology bulletin, 2021, 06-01, Volume: 51, Issue:3

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Humans; Mirtazapine; Propranolol; Psychomotor Agitati

2021
A meta-analysis of eight randomized, double-blind, controlled clinical trials of mirtazapine for the treatment of patients with major depression and symptoms of anxiety.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Depress

1998

Trials

1 trial available for mirtazapine and Psychomotor Agitation

ArticleYear
Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2021, 10-23, Volume: 398, Issue:10310

    Topics: Aged, 80 and over; Anti-Anxiety Agents; Brief Psychiatric Rating Scale; Caregivers; Dementia; Double

2021

Other Studies

3 other studies available for mirtazapine and Psychomotor Agitation

ArticleYear
Mirtazapine Treatment for Azithromycin-Associated Akathisia.
    American journal of therapeutics, 2020, 10-01, Volume: 28, Issue:6

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Azithromycin; Humans; Mirtazapine; Psychomotor Agitat

2020
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
    Nederlands tijdschrift voor geneeskunde, 2016, Volume: 160

    Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans;

2016
Clinical pharmacology of mirtazapine: revisited.
    American family physician, 1999, Sep-15, Volume: 60, Issue:4

    Topics: Agranulocytosis; Antidepressive Agents, Tricyclic; Anxiety; Depression; Humans; Mianserin; Mirtazapi

1999