Page last updated: 2024-10-31

mirtazapine and Parkinsonian Disorders

mirtazapine has been researched along with Parkinsonian Disorders in 5 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Research Excerpts

ExcerptRelevanceReference
"Shortly after initiation of mirtazapine (a noradrenergic and serotonergic antidepressant) treatment in four patients with parkinsonism, the authors observed the appearance of REM sleep behavior disorder (RBD)."7.72Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. ( D'Andreamatteo, G; Iacono, D; Luciano, AL; Onofrj, M; Thomas, A, 2003)
"Shortly after initiation of mirtazapine (a noradrenergic and serotonergic antidepressant) treatment in four patients with parkinsonism, the authors observed the appearance of REM sleep behavior disorder (RBD)."3.72Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. ( D'Andreamatteo, G; Iacono, D; Luciano, AL; Onofrj, M; Thomas, A, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Godschalx-Dekker, JA1
Siegers, HP1
Holtz, NA1
Tedford, SE1
Persons, AL1
Grasso, SA1
Napier, TC1
Hamadjida, A1
Nuara, SG1
Veyres, N1
Frouni, I1
Kwan, C1
Sid-Otmane, L1
Harraka, MJ1
Gourdon, JC1
Huot, P1
Onofrj, M1
Luciano, AL1
Thomas, A1
Iacono, D1
D'Andreamatteo, G1
Nash, JR1
Wilson, SJ1
Potokar, JP1
Nutt, DJ1

Other Studies

5 other studies available for mirtazapine and Parkinsonian Disorders

ArticleYear
Reduction of parkinsonism and psychosis with mirtazapine: a case report.
    Pharmacopsychiatry, 2014, Volume: 47, Issue:3

    Topics: Aged; Histamine H1 Antagonists; Humans; Male; Mianserin; Mirtazapine; Parkinsonian Disorders; Psycho

2014
Pharmacologically distinct pramipexole-mediated akinesia vs. risk-taking in a rat model of Parkinson's disease.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 10-03, Volume: 70

    Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Corpus Striatum; De

2016
The effect of mirtazapine on dopaminergic psychosis and dyskinesia in the parkinsonian marmoset.
    Psychopharmacology, 2017, Volume: 234, Issue:6

    Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Behavior, Animal; Callithrix; Dyski

2017
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
    Neurology, 2003, Jan-14, Volume: 60, Issue:1

    Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Electroencephalography; Humans; Levodopa; Male;

2003
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
    Neurology, 2003, Oct-28, Volume: 61, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Drug Administration Schedule; Hu

2003