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mirtazapine and Mental Disorders

mirtazapine has been researched along with Mental Disorders in 17 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"Mirtazapine is an antidepressant with a mechanism that involves activating serotonin (5-HT1) receptors."6.47Mirtazapine relieves post-electroconvulsive therapy headaches and nausea: a case series and review of the literature. ( Huang, KC; Lee, WK; Li, TC; Shiah, IS; Sun, CJ; Tzang, RF, 2011)
" The most often off-label prescribed drugs were quetiapine and mirtazapine for organic mental disorders (F0/G3), valproate and quetiapine in patients with disorders due to psychoactive substance use (F1), valproate in patients with psychotic disorders (F2), and risperidone and olanzapine in patients with affective disorders (F3)."4.12Off-label use of antidepressants, antipsychotics, and mood-stabilizers in psychiatry. ( Hefner, G; Klimke, A; Reißner, P; Toto, S; Wolff, J, 2022)
"Mirtazapine is an antidepressant with a mechanism that involves activating serotonin (5-HT1) receptors."2.47Mirtazapine relieves post-electroconvulsive therapy headaches and nausea: a case series and review of the literature. ( Huang, KC; Lee, WK; Li, TC; Shiah, IS; Sun, CJ; Tzang, RF, 2011)
"Mirtazapine (7."1.48Very Low-Dose Mirtazapine (7.5 mg) in Treatment of Acute Antipsychotic-Associated Akathisia. ( Poyurovsky, M; Weizman, A, 2018)
"Mirtazapine is an antidepressant that acts by enhancing serotonergic and noradrenergic neurotransmission."1.40Therapeutic drug monitoring of mirtazapine in a routine outpatient setting in Asian psychiatric patients. ( Jang, JH; Kim, DK; Lee, SY; Myung, W; Yoon, H, 2014)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (35.29)29.6817
2010's8 (47.06)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Ciccarone, D1
Shoptaw, S1
Hefner, G1
Wolff, J1
Toto, S1
Reißner, P1
Klimke, A1
Al-Khalil, M1
Sack, A1
Elson, R1
Pleat, J1
Poyurovsky, M2
Weizman, A2
Hutchins, D1
Hall, J1
Sharma, A1
Shinozaki, M1
Pierce, J1
Hayashi, Y1
Watanabe, T1
Sasaki, T1
Komahashi-Sasaki, H1
Akiyama, K1
Kato, K1
Inoue, Y1
Tsuchimine, S1
Yasui-Furukori, N1
Ozeki, Y1
Shimoda, K1
Myung, W1
Jang, JH1
Yoon, H1
Lee, SY1
Kim, DK1
Paulzen, M1
Gründer, G1
Tauber, SC1
Veselinovic, T1
Hiemke, C1
Groppe, SE1
Grover, S1
Avasthi, A1
Tripathi, A1
Tanra, AJ1
Chee, KY1
He, YL1
Chiu, HF1
Kuga, H1
Lee, MS1
Chong, MY1
Udormatn, P1
Kanba, S1
Yang, SY1
Si, TM1
Sim, K1
Tan, CH1
Shen, WW1
Xiang, YT1
Sartorius, N1
Shinfuku, N1
Li, TC1
Shiah, IS1
Sun, CJ1
Tzang, RF1
Huang, KC1
Lee, WK1
Banerjee, S1
Hellier, J1
Dewey, M1
Romeo, R1
Ballard, C1
Baldwin, R1
Bentham, P1
Fox, C1
Holmes, C1
Katona, C1
Knapp, M1
Lawton, C1
Lindesay, J1
Livingston, G1
McCrae, N1
Moniz-Cook, E1
Murray, J1
Nurock, S1
Orrell, M1
O'Brien, J1
Poppe, M1
Thomas, A1
Walwyn, R1
Wilson, K1
Burns, A1
Juckel, G2
Schüle, C1
Pogarell, O2
Rupp, D1
Laakmann, G1
Hegerl, U2
Kozyrev, VN1
Smulevich, AB1
Drobizhev, MIu1
Kraeva, GK1
Kubrakov, MA1
Szegedi, A1
Schwertfeger, N1
Zullino, D1
Mayland, G1
Schmidt, LG1
Fähndrich, E1
Greil, W1
Horvath, A1
Rüther, E1
Engel, R1
Hippius, H1
Baumann, P1
Pashinian, A1
Weizman, R1
Fuchs, C1
Sterr, A1
Padberg, F1
Amann, B1
Mergl, R1
Mulert, C1

Reviews

4 reviews available for mirtazapine and Mental Disorders

ArticleYear
Understanding Stimulant Use and Use Disorders in a New Era.
    The Medical clinics of North America, 2022, Volume: 106, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Anticonvulsants; Behavior Therapy; Bupropion; Centra

2022
Mirtazapine relieves post-electroconvulsive therapy headaches and nausea: a case series and review of the literature.
    The journal of ECT, 2011, Volume: 27, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Electroconvulsive Therapy; Fema

2011
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial.
    Lancet (London, England), 2011, Jul-30, Volume: 378, Issue:9789

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Do

2011
Mirtazapine: a review of its clinical efficacy and tolerability.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:4

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Humans; Mental Disorder

2005

Trials

2 trials available for mirtazapine and Mental Disorders

ArticleYear
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial.
    Lancet (London, England), 2011, Jul-30, Volume: 378, Issue:9789

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Do

2011
Low-dose mirtazapine: a new option in the treatment of antipsychotic-induced akathisia. A randomized, double-blind, placebo- and propranolol-controlled trial.
    Biological psychiatry, 2006, Jun-01, Volume: 59, Issue:11

    Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents, Tr

2006

Other Studies

12 other studies available for mirtazapine and Mental Disorders

ArticleYear
Off-label use of antidepressants, antipsychotics, and mood-stabilizers in psychiatry.
    Journal of neural transmission (Vienna, Austria : 1996), 2022, Volume: 129, Issue:11

    Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Female; Humans; Male; Mental Disorders

2022
A 5-year single-centre retrospective study of potential drug interactions in burns inpatients with psychiatric comorbidities.
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:5

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents; Arrhythmias, Cardiac; Burns; Comorbidity; Drug Int

2020
Very Low-Dose Mirtazapine (7.5 mg) in Treatment of Acute Antipsychotic-Associated Akathisia.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:6

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Female; Humans; Male; Mental Disorders; Middle

2018
Mirtazapine-Induced Transient Dyskinesia.
    The primary care companion for CNS disorders, 2019, Apr-04, Volume: 21, Issue:2

    Topics: Antidepressive Agents; Dyskinesia, Drug-Induced; Female; Humans; Mental Disorders; Middle Aged; Mirt

2019
8-Hydroxylation and Glucuronidation of Mirtazapine in Japanese Psychiatric Patients: Significance of the Glucuronidation Pathway of 8-Hydroxy-Mirtazapine.
    Pharmacopsychiatry, 2019, Volume: 52, Issue:5

    Topics: Age Factors; Alleles; Anti-Anxiety Agents; Asian People; Cytochrome P-450 CYP2D6; Genotype; Glucuron

2019
Therapeutic drug monitoring of mirtazapine in a routine outpatient setting in Asian psychiatric patients.
    Pharmacopsychiatry, 2014, Volume: 47, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Age Factors; Aged; Dose-Response Relationship, Drug; Drug Monit

2014
Distribution pattern of mirtazapine and normirtazapine in blood and CSF.
    Psychopharmacology, 2015, Volume: 232, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Blood-Brain Barrier; Female; Humans; Male; Mental Dis

2015
Antidepressant Prescription Pattern in the Presence of Medical Co-morbidity: REAP-AD 2013 Study.
    East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2015, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Tricyclic;

2015
Epileptiform EEG patterns induced by mirtazapine in both psychiatric patients and healthy volunteers.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:4

    Topics: Adult; Antidepressive Agents; Electroencephalography; Epilepsy; Female; Humans; Mental Disorders; Mi

2003
[Psychotropic drugs used in a psychiatric hospital (pharmaco-epidemiologic aspects)].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:11

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepin

2003
Prescribing practices in German and Swiss psychiatric university and in non-university hospitals: national differences.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Community Mental Health Centers; Drug Presc

2005
Electroencephalographic abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine, and amitriptyline.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Cerebral Cortex; Citalopram; Cyclohexanols; Electroence

2006