mirtazapine has been researched along with MPTP Neurotoxicity Syndrome in 2 studies
Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mirtazapine was also reported to increase dopamine release in the cortical neurons with 5-HT dependent manner." | 1.40 | Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease. ( Fukano, T; Kadoguchi, N; Kasahara, J; Okabe, S; Shono, M; Tanabe, A; Yamamura, Y; Yokoyama, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kadoguchi, N | 1 |
| Okabe, S | 1 |
| Yamamura, Y | 1 |
| Shono, M | 1 |
| Fukano, T | 1 |
| Tanabe, A | 1 |
| Yokoyama, H | 1 |
| Kasahara, J | 1 |
| Hamadjida, A | 1 |
| Nuara, SG | 1 |
| Veyres, N | 1 |
| Frouni, I | 1 |
| Kwan, C | 1 |
| Sid-Otmane, L | 1 |
| Harraka, MJ | 1 |
| Gourdon, JC | 1 |
| Huot, P | 1 |
2 other studies available for mirtazapine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Disease Models, Animal; Feasibility Studies; Male; | 2014 |
The effect of mirtazapine on dopaminergic psychosis and dyskinesia in the parkinsonian marmoset.
Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Behavior, Animal; Callithrix; Dyski | 2017 |