Page last updated: 2024-10-31

mirtazapine and Headache

mirtazapine has been researched along with Headache in 7 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Mirtazapine is an antidepressant with a mechanism that involves activating serotonin (5-HT1) receptors."6.47Mirtazapine relieves post-electroconvulsive therapy headaches and nausea: a case series and review of the literature. ( Huang, KC; Lee, WK; Li, TC; Shiah, IS; Sun, CJ; Tzang, RF, 2011)
"Primary care patients with a major depressive disorder and 17-item Hamilton Rating Scale for Depression (17-HAM-D) score >18 were randomized to 24 weeks of treatment with mirtazapine 30-45 mg/day (n=99) or paroxetine 20-30 mg/day (n=98)."5.10A randomized, double-blind, 24-week study comparing the efficacy and tolerability of mirtazapine and paroxetine in depressed patients in primary care. ( Angus, M; Crawford, GM; Hamilton, L; Wade, A; Wilson, R, 2003)
"Mirtazapine is a third-generation antidepressant with a dual mode of action."2.72Intravenous mirtazapine is safe and effective in the treatment of depressed inpatients. ( Egger, C; Eichberger, G; Hinterhuber, H; Hofmann, P; Kasper, S; Konstantinidis, A; Mühlbacher, M; Nickel, M; Nimmerrichter, A; Schubert, H; Stuppaeck, C, 2006)
"Mirtazapine is an antidepressant with a mechanism that involves activating serotonin (5-HT1) receptors."2.47Mirtazapine relieves post-electroconvulsive therapy headaches and nausea: a case series and review of the literature. ( Huang, KC; Lee, WK; Li, TC; Shiah, IS; Sun, CJ; Tzang, RF, 2011)
" The rates for individual side effects with the serotonin selective reuptake inhibitors, nefazodone, and venlafaxine are presented and compared with the adverse event experience for mirtazapine."2.40Safety and tolerability of the new antidepressants. ( Nelson, JC, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, JH1
Li, TC1
Shiah, IS1
Sun, CJ1
Tzang, RF1
Huang, KC1
Lee, WK1
Wade, A1
Crawford, GM1
Angus, M1
Wilson, R1
Hamilton, L1
Mühlbacher, M1
Konstantinidis, A1
Kasper, S1
Eichberger, G1
Hinterhuber, H1
Hofmann, P1
Nimmerrichter, A1
Schubert, H1
Egger, C1
Nickel, M1
Stuppaeck, C1
Nelson, JC1
Wheatley, DP1
van Moffaert, M1
Timmerman, L1
Kremer, CM1
Spierings, EL1

Reviews

2 reviews available for mirtazapine and Headache

ArticleYear
Mirtazapine relieves post-electroconvulsive therapy headaches and nausea: a case series and review of the literature.
    The journal of ECT, 2011, Volume: 27, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Electroconvulsive Therapy; Fema

2011
Safety and tolerability of the new antidepressants.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 6

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressiv

1997

Trials

3 trials available for mirtazapine and Headache

ArticleYear
A randomized, double-blind, 24-week study comparing the efficacy and tolerability of mirtazapine and paroxetine in depressed patients in primary care.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepress

2003
Intravenous mirtazapine is safe and effective in the treatment of depressed inpatients.
    Neuropsychobiology, 2006, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Fatigue; Fema

2006
Mirtazapine: efficacy and tolerability in comparison with fluoxetine in patients with moderate to severe major depressive disorder. Mirtazapine-Fluoxetine Study Group.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:6

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Administration

1998

Other Studies

2 other studies available for mirtazapine and Headache

ArticleYear
Mirtazapine for new daily persistent headache-associated chronic nausea.
    Headache, 2015, Volume: 55, Issue:1

    Topics: Chronic Disease; Female; Headache; Histamine H1 Antagonists; Humans; Mianserin; Middle Aged; Mirtaza

2015
Acute and chronic hypertensive headache and hypertensive encephalopathy.
    Cephalalgia : an international journal of headache, 2002, Volume: 22, Issue:4

    Topics: Acute Disease; Antidepressive Agents; Antihypertensive Agents; Anxiety; Arterioles; Cerebral Arterie

2002