Page last updated: 2024-10-31

mirtazapine and HIV Infections

mirtazapine has been researched along with HIV Infections in 8 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

HIV Infections: Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).

Research Excerpts

ExcerptRelevanceReference
"Mirtazapine use was safe and well tolerated."2.74Mirtazapine use in human immunodeficiency virus-infected patients with progressive multifocal leukoencephalopathy. ( Cettomai, D; McArthur, JC, 2009)
"Treatment with mirtazapine 30 mg orally daily and mefloquine hydrochloride 250 mg orally for three days, then 250 mg weekly, was initiated."1.38Mirtazapine and mefloquine therapy for progressive multifocal leukoencephalopathy in a patient infected with human immunodeficiency virus. ( Jett, RA; Moenster, RP, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Lee, F1
Sheeler, D1
Hotton, A1
Vecchio, ND1
Flores, R1
Fujimoto, K1
Harawa, N1
Schneider, JA1
Khanna, AS1
Cifci, B1
Yildiz, Y1
Altin, E1
Habibi, H1
Kocer, B1
Dizbay, M1
Coffin, PO1
Santos, GM1
Hern, J1
Vittinghoff, E1
Walker, JE1
Matheson, T1
Santos, D1
Colfax, G1
Batki, SL1
Iannetta, M1
Bellizzi, A1
Lo Menzo, S1
Anzivino, E1
D'Abramo, A1
Oliva, A1
D'Agostino, C1
d'Ettorre, G1
Pietropaolo, V1
Vullo, V1
Ciardi, MR1
Loignon, M1
Toma, E1
Cettomai, D1
McArthur, JC1
Mischo, M1
Nigg, C1
Kiss, A1
Moenster, RP1
Jett, RA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Mirtazapine for the Treatment of Methamphetamine Dependence Among MSM: a 6-month Randomized Controlled Trial With 3 Months of Follow-up[NCT01888835]Phase 2120 participants (Actual)Interventional2013-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for mirtazapine and HIV Infections

ArticleYear
Treatment options for progressive multifocal leukoencephalopathy in HIV-infected persons: current status and future directions.
    Expert review of anti-infective therapy, 2016, Volume: 14, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Coinfection; Cy

2016
[Depression].
    Praxis, 2010, Mar-03, Volume: 99, Issue:5

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; C

2010

Trials

2 trials available for mirtazapine and HIV Infections

ArticleYear
Effects of Mirtazapine for Methamphetamine Use Disorder Among Cisgender Men and Transgender Women Who Have Sex With Men: A Placebo-Controlled Randomized Clinical Trial.
    JAMA psychiatry, 2020, 03-01, Volume: 77, Issue:3

    Topics: Adult; Amphetamine-Related Disorders; Double-Blind Method; Female; HIV Infections; Homosexuality, Ma

2020
Mirtazapine use in human immunodeficiency virus-infected patients with progressive multifocal leukoencephalopathy.
    Archives of neurology, 2009, Volume: 66, Issue:2

    Topics: Adult; Blood-Brain Barrier; Brain; Drug Administration Schedule; Early Diagnosis; Female; HIV Infect

2009

Other Studies

4 other studies available for mirtazapine and HIV Infections

ArticleYear
Stimulant use interventions may strengthen 'Getting to Zero' HIV elimination initiatives in Illinois: Insights from a modeling study.
    The International journal on drug policy, 2022, Volume: 103

    Topics: Central Nervous System Stimulants; HIV Infections; Homosexuality, Male; Humans; Illinois; Male; Meth

2022
Successful treatment of HIV-associated progressive multifocal leukoencephalopathy (PML) with mirtazapine, mefloquine, and IVIG combination therapy: a case report.
    Journal of neurovirology, 2023, Volume: 29, Issue:1

    Topics: HIV Infections; Humans; Immunoglobulins, Intravenous; JC Virus; Leukoencephalopathy, Progressive Mul

2023
HIV-associated progressive multifocal leukoencephalopathy: longitudinal study of JC virus non-coding control region rearrangements and host immunity.
    Journal of neurovirology, 2013, Volume: 19, Issue:3

    Topics: Adrenal Cortex Hormones; Antiretroviral Therapy, Highly Active; Antiviral Agents; Coinfection; Fatal

2013
Mirtazapine and mefloquine therapy for progressive multifocal leukoencephalopathy in a patient infected with human immunodeficiency virus.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Mar-15, Volume: 69, Issue:6

    Topics: Cognition Disorders; Histamine H1 Antagonists; HIV Infections; Humans; JC Virus; Leukoencephalopathy

2012